Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Ella Mae Matsumura, Rachna Prakash, Sandra C. Vera‐Muñoz · 2022 · Review of Accounting Studies
Abstract Managers are required to disclose material climate risk in Form 10-K, but their decision whether or not to disclose is confounded by the lack of consensus on whether climate risk is material to the firms, as well as uncertainty about enforcement of disclosure regulations. Using the SASB Materiality Map™ to proxy for market expectations of climate risk materiality, we test whether the association between disclosing climate risk in 10-Ks and firm risk (proxied by cost of equity (COE)) varies with market expectations of climate risk materiality. Using S&P 500 firms’ decisions whether
View details →Negative / Null Result ReportEconomics, Econometrics and Finance
Ahmet Köseoğlu, Ali Gökhan Yücel, Recep Ulucak · 2022 · Sustainable Development
Abstract The ecological pressure of humanity on the planet measured by ecological footprint has been enlarging, which upsurges environmental threats. At this point, green innovation emerges as an optimal solution to sustainable development…
View details →Negative / Null Result ReportOpen accessMedicine
Nina Johnston, Johan Bodegård, Susanna Jerström et al. · 2016 · American Heart Journal
BACKGROUND: Patients with myocardial infarction (MI) seldom reach recommended targets for secondary prevention. This study evaluated a smartphone application ("app") aimed at improving treatment adherence and cardiovascular lifestyle in MI…
View details →Negative / Null Result ReportMedicine
Shannon Fraser, Paul A. Gardner, Maria Koutourousiou et al. · 2017 · Journal of neurosurgery
OBJECTIVE The aim in this paper was to determine risk factors for the development of a postoperative CSF leak after an endoscopic endonasal approach (EEA) for resection of skull base tumors. METHODS A retrospective review of patients who…
View details →Negative / Null Result ReportOpen accessMedicine
Roham T. Zamanian, David B. Badesch, Lorinda Chung et al. · 2021 · American Journal of Respiratory and Critical Care Medicine
Abstract Rationale Systemic sclerosis (SSc)–pulmonary arterial hypertension (PAH) is one of the most prevalent and deadly forms of PAH. B cells may contribute to SSc pathogenesis. Objectives We investigated the safety and efficacy of…
View details →Negative / Null Result ReportPsychology
Sara E. Rimm‐Kaufman, Ross Larsen, Alison E. Baroody et al. · 2014 · American Educational Research Journal
This randomized controlled field trial examined the efficacy of the Responsive Classroom ( RC) approach on student achievement. Schools ( n = 24) were randomized into intervention and control conditions; 2,904 children were studied from…
View details →Negative / Null Result ReportMedicine
Angela Kuznia, Anita K Hernandez, Lydia U Lee · 2020 · PubMed
Adolescent idiopathic scoliosis affects 1% to 3% of U.S. adolescents. It is defined by a lateral curvature of the spine (Cobb angle) of at least 10 degrees in the absence of underlying congenital or neuromuscular abnormalities. Adolescent…
View details →Negative / Null Result ReportMedicine
Peter Sundström, Anders Wåhlin, Khalid Ambarki et al. · 2010 · Annals of Neurology
The prevailing view on multiple sclerosis etiopathogenesis has been challenged by the suggested new entity chronic cerebrospinal venous insufficiency. To test this hypothesis, we studied 21 relapsing-remitting multiple sclerosis cases and…
View details →Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology
Konstantinos K. Tsilidis, Despoina Capothanassi, Naomi E. Allen et al. · 2014 · Diabetes Care
OBJECTIVE: Meta-analyses of epidemiologic studies have suggested that metformin may reduce cancer incidence, but randomized controlled trials did not support this hypothesis. RESEARCH DESIGN AND METHODS: A retrospective cohort study,…
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Haibo Zhou, Rommert Dekker, A.H. Kleinknecht · 2011 · Industrial and Corporate Change
Firms with high shares of workers on fixed-term contracts tend to have higher sales of imitative new products but perform significantly worse on sales of innovative new products ("first on the market"). High functional flexibility in…
View details →Negative / Null Result ReportOpen accessMedicine
Myung‐Ju Ahn, Kentaro Tanaka, Luis Paz‐Ares et al. · 2024 · Journal of Clinical Oncology
PURPOSE The randomized, open-label, global phase III TROPION-Lung01 study compared the efficacy and safety of datopotamab deruxtecan (Dato-DXd) versus docetaxel in patients with pretreated advanced/metastatic non–small cell lung cancer…
View details →Negative / Null Result ReportOpen accessMedicine
DK Patel, R Kumar, SK Prasad et al. · 2011 · Asian Pacific Journal of Tropical Biomedicine
OBJECTIVE: To evaluate antidiabetic and antioxidant potential of Hybanthus enneaspermus in different models. METHODS: The oral glucose tolerance test (OGTT) and normoglycemic effect of alcoholic extract of Hybanthus enneaspermus (AHE) were…
View details →Negative / Null Result ReportMedicine
Ilaria Montagni, Elie Guichard, Claire Carpenet et al. · 2015 · Cephalalgia
Objective The objective of this article is to investigate whether excessive screen time exposure is associated with non-migraine headache and migraine in young adults. Background Increased levels of television time have been associated…
View details →Negative / Null Result ReportComputer Science
Guido Makransky, Gustav Bøg Petersen, Sara Klingenberg · 2020 · British Journal of Educational Technology
Abstract Science‐related competencies are demanded in many fields, but attracting more students to scientific educations remains a challenge. This paper uses two studies to investigate the value of using Immersive Virtual Reality (IVR)…
View details →Negative / Null Result ReportOpen accessMedicine
Miriam M. Boxer, Shalini Vinod, Jesmin Shafiq et al. · 2011 · Cancer
BACKGROUND: There is limited evidence regarding the effectiveness of multidisciplinary team (MDT) meetings in lung cancer. The objective of this study was to compare the patterns of care for patients with newly diagnosed lung cancer who…
View details →Negative / Null Result ReportOpen accessMedicine
Ranjani R. Starr · 2015 · American Journal of Public Health
Millions of people in the United States consume dietary supplements hoping to maintain or improve their health; however, extensive research has failed to demonstrate the efficacy of numerous supplements in disease prevention. In addition,…
View details →Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Chinedu Francis Egbunike, Chinedu U. Okerekeoti · 2018 · Asian Journal of Accounting Research
Purpose The purpose of this paper is to explore the interrelationship between macroeconomic factors, firm characteristics and financial performance of quoted manufacturing firms in Nigeria. Specifically, the study investigates the effect of interest rate, inflation rate, exchange rate and the gross domestic product (GDP) growth rate, while the firm characteristics were size, leverage and liquidity. The dependent variable financial performance is measured as return on assets (ROA). Design/methodology/approach The study used the ex post facto research design. The population comprised all quoted
View details →Negative / Null Result ReportMedicine
J. F. Keating, Elizabeth Will · 2011 · Journal of Bone and Joint Surgery - British Volume
A total of 80 patients with an acute rupture of tendo Achillis were randomised to operative repair using an open technique (39 patients) or non-operative treatment in a cast (41 patients). Patients were followed up for one year. Outcome…
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Michele Casini, Filip Käll, Martin Hansson et al. · 2016 · Royal Society Open Science
) in the Baltic Sea has dramatically decreased during the past two decades, with large implications for the fishery relying on this resource. Here, we statistically investigated the potential drivers of the Baltic cod condition during the past 40 years using newly compiled fishery-independent biological data and hydrological observations. We evidenced a combination of different factors operating before and after the ecological regime shift that occurred in the Baltic Sea in the early 1990s. The changes in cod condition related to feeding opportunities, driven either by density-dependence or fo
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Jennifer Stowell, Guannan Geng, Eri Saikawa et al. · 2019 · Environment International
BACKGROUND: exposure. OBJECTIVES: levels. METHODS: for overall and age-stratified outcomes using 2-day averaging windows for cardiovascular disease and 3-day windows for respiratory disease. RESULTS: were observed for asthma and combined respiratory disease in children, and for asthma, bronchitis, COPD, and combined respiratory disease in adults. No significant associations were found in older adults. DISCUSSION: exposure in a changing climate.
View details →Negative / Null Result ReportNeuroscience
Karl Nordström, Markus Sällman Almén, Monika M. Edstam et al. · 2011 · Molecular Biology and Evolution
Several families of G protein-coupled receptors (GPCRs) show no significant sequence similarities to each other, and it has been debated which of them share a common origin. We developed and performed integrated and independent HHsearch,…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Tim Schneider, Lee-Hsueh Hung, Silke Schreiner et al. · 2016 · Scientific Reports
Circular RNAs (circRNAs) constitute a new class of noncoding RNAs in higher eukaryotes generated from pre-mRNAs by alternative splicing. Here we investigated in mammalian cells the association of circRNAs with proteins. Using glycerol gradient centrifugation, we characterized in cell lysates circRNA-protein complexes (circRNPs) of distinct sizes. By polysome-gradient fractionation we found no evidence for efficient translation of a set of abundant circRNAs in HeLa cells. To identify circRNPs with a specific protein component, we focused on IMP3 (IGF2BP3, insulin-like growth factor 2 binding pr
View details →Negative / Null Result ReportOpen accessHealth Professions
Eva van het Reve, Patrícia Silveira, Florian Daniel et al. · 2014 · Journal of Medical Internet Research
BACKGROUND: Home-based exercise programs can improve physical functioning and health status of elderly people. Successful implementation of exercise interventions for older people presents major challenges and supporting elderly people properly while doing their home-based exercises is essential for training success. We developed a tablet-based system-ActiveLifestyle-that offers older adults a home-based strength-balance training program with incorporated motivation strategies and support features. OBJECTIVE: The goal was to compare 3 different home-based training programs with respect to thei
View details →Negative / Null Result ReportOpen accessMedicine
Robert H. Squires, Anil Dhawan, Estella M. Alonso et al. · 2012 · Hepatology
UNLABELLED: N-acetylcysteine (NAC) was found to improve transplantation-free survival in only those adults with nonacetaminophen (non-APAP) acute liver failure (ALF) and grade 1-2 hepatic encephalopathy (HE). Because non-APAP ALF differs…
View details →Negative / Null Result ReportOpen accessMathematics
Erin Hartman, F. Daniel Hidalgo · 2018 · American Journal of Political Science
Abstract Recent emphasis on credible causal designs has led to the expectation that scholars justify their research designs by testing the plausibility of their causal identification assumptions, often through balance and placebo tests.…
View details →Negative / Null Result ReportOpen accessMedicine
Armin Zittermann, Jana B. Ernst, Sylvana Prokop et al. · 2017 · European Heart Journal
AIMS: Circulating 25-hydroxyvitamin D (25OHD) levels <75 nmol/L are associated with a nonlinear increase in mortality risk. Such 25OHD levels are common in heart failure (HF). We therefore examined whether oral vitamin D supplementation…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Seema A. Khan, Fengmin Zhao, Lori J. Goldstein et al. · 2022 · Journal of Clinical Oncology
PURPOSE Distant metastases are present in 6% or more of patients with newly diagnosed breast cancer. In this context, locoregional therapy for the intact primary tumor has been hypothesized to improve overall survival (OS), but clinical…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Alex Nisthal, Connie Y. Wang, Marylouise Ary et al. · 2019 · Proceedings of the National Academy of Sciences
The accurate prediction of protein stability upon sequence mutation is an important but unsolved challenge in protein engineering. Large mutational datasets are required to train computational predictors, but traditional methods for…
View details →Negative / Null Result ReportOpen accessMaterials Science
Deniz Çakır, Cem Sevik, F. M. Peeters · 2015 · Physical Review B
The effect of the number of stacking layers and the type of stacking on the electronic and optical properties of bilayer and trilayer black phosphorus are investigated by using first-principles calculations within the framework of density…
View details →Negative / Null Result ReportOpen accessMathematics
Joseph L. Dieleman, Tara Templin · 2014 · PLoS ONE
BACKGROUND: When unaccounted-for group-level characteristics affect an outcome variable, traditional linear regression is inefficient and can be biased. The random- and fixed-effects estimators (RE and FE, respectively) are two competing methods that address these problems. While each estimator controls for otherwise unaccounted-for effects, the two estimators require different assumptions. Health researchers tend to favor RE estimation, while researchers from some other disciplines tend to favor FE estimation. In addition to RE and FE, an alternative method called within-between (WB) was sugg
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