e-ISSN: Pending
Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 178

Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (E2108)

Seema A. Khan; Fengmin Zhao; Lori J. Goldstein; David Cella; Mark Basik; Mehra Golshan; Thomas B. Julian; Barbara A. Pockaj · 2022 · Journal of Clinical Oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

PURPOSE Distant metastases are present in 6% or more of patients with newly diagnosed breast cancer. In this context, locoregional therapy for the intact primary tumor has been hypothesized to improve overall survival (OS), but clinical…

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Metadata source: OpenAlex · DOI 10.1200/jco.21.02006