Negative / Null Result ReportOpen accessMedicine
Gary Cook, Connie Yip, Muhammad Siddique et al. · 2012 · Journal of Nuclear Medicine
UNLABELLED: There is evidence in some solid tumors that textural features of tumoral uptake in (18)F-FDG PET images are associated with response to chemoradiotherapy and survival. We have investigated whether a similar relationship exists…
View details →DOI: 10.2967/jnumed.112.107375Cited by 394 Negative / Null Result ReportOpen accessMedicine
Kevin C. Soares, Agnieszka A. Rucki, Annie A. Wu et al. · 2014 · Journal of Immunotherapy
Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis due to late detection and resistance to conventional therapies. Published studies show that the PDA tumor microenvironment is predominantly infiltrated with immune suppressive…
View details →DOI: 10.1097/cji.0000000000000062Cited by 394 Negative / Null Result ReportOpen accessHealth Professions
Amy Chesser, Nikki Keene Woods, Kyle Smothers et al. · 2016 · Gerontology and Geriatric Medicine
Objective: The objective of this review was to assess published literature relating to health literacy and older adults. Method: The current review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta…
View details →DOI: 10.1177/2333721416630492Cited by 392 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Hansong Chen, Zhen Tian · 2021 · Journal of Business Research
Digital transformation is essential if enterprises are to obtain a competitive advantage in the digital economy. However, successful transformation is a problem for both academia and industry. The literature mainly focuses on the net…
View details →DOI: 10.1016/j.jbusres.2021.09.048Cited by 392 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Georgina Mansell, T.J. Gorrie-Stone, Yanchun Bao et al. · 2019 · BMC Genomics
There has been a steady increase in the number of studies aiming to identify DNA methylation differences associated with complex phenotypes. Many of the challenges of epigenetic epidemiology regarding study design and interpretation have been discussed in detail, however there are analytical concerns that are outstanding and require further exploration. In this study we seek to address three analytical issues. First, we quantify the multiple testing burden and propose a standard statistical significance threshold for identifying DNA methylation sites that are associated with an outcome. Second
View details →DOI: 10.1186/s12864-019-5761-7Cited by 391 Negative / Null Result ReportOpen accessMedicine
Matthew J. Ward, Stephen M. Thirdborough, Toby Mellows et al. · 2013 · British Journal of Cancer
BACKGROUND: Human papillomavirus (HPV)-positive oropharyngeal cancer (OPSCC) is associated with improved survival compared with HPV-negative disease. However, a minority of HPV-positive patients have poor prognosis. Currently, there is no…
View details →DOI: 10.1038/bjc.2013.639Cited by 391 Negative / Null Result ReportOpen accessMedicine
Lai-ping Zhong, Chen-ping Zhang, Guo-xin Ren et al. · 2012 · Journal of Clinical Oncology
PURPOSE: To evaluate induction chemotherapy with docetaxel, cisplatin, and fluorouracil (TPF) followed by surgery and postoperative radiotherapy versus up-front surgery and postoperative radiotherapy in patients with locally advanced…
View details →DOI: 10.1200/jco.2012.43.8820Cited by 391 Negative / Null Result ReportOpen accessEnvironmental Science
Rachel E. McNeish, L. H. Kim, Heather A. Barrett et al. · 2018 · Scientific Reports
Abstract Microplastic is a contaminant of concern worldwide. Rivers are implicated as major pathways of microplastic transport to marine and lake ecosystems, and microplastic ingestion by freshwater biota is a risk associated with microplastic contamination, but there is little research on microplastic ecology within freshwater ecosystems. Microplastic uptake by fish is likely affected by environmental microplastic abundance and aspects of fish ecology, but these relationships have rarely been addressed. We measured the abundance and composition of microplastic in fish and surface waters from
View details →DOI: 10.1038/s41598-018-29980-9Cited by 391 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Gerhard Kling, Ulrich Volz, Victor Murinde et al. · 2020 · World Development
This article presents the first systematic investigation of the effects of climate-related vulnerability on firms’ cost of capital and access to finance and sheds light on a hitherto under-appreciated cost of climate change for climate vulnerable developing economies. We first show theoretically how climate vulnerability could affect firms’ cost of capital and access to finance. Apart from a possible impact on cost of debt and equity, which drive cost of capital, firms in countries with high exposure to climate risk might be more financially constrained. The latter results in low levels of deb
View details →DOI: 10.1016/j.worlddev.2020.105131Cited by 390 Negative / Null Result ReportOpen accessDentistry
Mario Imburgia, Silvia Logozzo, Uli Hauschild et al. · 2017 · BMC Oral Health
BACKGROUND: Until now, only a few studies have compared the ability of different intraoral scanners (IOS) to capture high-quality impressions in patients with dental implants. Hence, the aim of this study was to compare the trueness and precision of four IOS in a partially edentulous model (PEM) with three implants and in a fully edentulous model (FEM) with six implants. METHODS: Two gypsum models were prepared with respectively three and six implant analogues, and polyether-ether-ketone cylinders screwed on. These models were scanned with a reference scanner (ScanRider®), and with four IOS (C
View details →DOI: 10.1186/s12903-017-0383-4Cited by 389 Negative / Null Result ReportOpen accessEnvironmental Science
Qiaohong Sun, Xuebin Zhang, Francis W. Zwiers et al. · 2020 · Journal of Climate
Abstract This paper provides an updated analysis of observed changes in extreme precipitation using high-quality station data up to 2018. We examine changes in extreme precipitation represented by annual maxima of 1-day (Rx1day) and 5-day…
View details →DOI: 10.1175/jcli-d-19-0892.1Cited by 389 Negative / Null Result ReportMedicine
Jay H. Traverse, Timothy D. Henry, Carl J. Pepine et al. · 2012 · JAMA
CONTEXT: While the delivery of cell therapy after ST-segment elevation myocardial infarction (STEMI) has been evaluated in previous clinical trials, the influence of the timing of cell delivery on the effect on left ventricular function…
View details →DOI: 10.1001/jama.2012.28726Cited by 388 Negative / Null Result ReportSocial Sciences
Haywantee Ramkissoon, Liam Smith, Betty Weiler · 2012 · Journal of Sustainable Tourism
Place attachment is a multidimensional construct comprising place dependence, place affect, place identity, and place social bonding. Yet, studies investigating the relationships between place attachment, place satisfaction, and…
View details →DOI: 10.1080/09669582.2012.708042Cited by 388 Negative / Null Result ReportOpen accessPsychology
Paola Ferri, Matteo Guadi, Luigi Marcheselli et al. · 2016 · Risk Management and Healthcare Policy
BACKGROUND: Shift work is considered necessary to ensure continuity of care in hospitals and residential facilities. In particular, the night shift is one of the most frequent reasons for the disruption of circadian rhythms, causing…
View details →DOI: 10.2147/rmhp.s115326Cited by 388 Negative / Null Result ReportOpen accessMedicine
Tom Jefferson, Mark Jones, Peter Doshi et al. · 2014 · Cochrane Database of Systematic Reviews
BACKGROUND: Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide. OBJECTIVES: To describe the potential…
View details →DOI: 10.1002/14651858.cd008965.pub4Cited by 388 Negative / Null Result ReportOpen accessPsychology
Kani Ülger · 2018 · Interdisciplinary Journal of Problem-based Learning
The problem-based learning (PBL) approach was implemented as a treatment for higher education visual arts students over one semester to examine its effect on the creative thinking and critical thinking disposition of these students. PBL…
View details →DOI: 10.7771/1541-5015.1649Cited by 387 Negative / Null Result ReportOpen accessImmunology and Microbiology
Dermot McGovern, Michelle R. Jones, Kent D. Taylor et al. · 2010 · Human Molecular Genetics
Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains unknown. We performed a genome-wide association study (GWAS) in 896 CD cases…
View details →DOI: 10.1093/hmg/ddq248Cited by 387 Negative / Null Result ReportEconomics, Econometrics and Finance
David Arnold, Will Dobbie, Crystal Yang · 2018 · The Quarterly Journal of Economics
Abstract This article develops a new test for identifying racial bias in the context of bail decisions—a high-stakes setting with large disparities between white and black defendants. We motivate our analysis using Becker’s model of racial…
View details →DOI: 10.1093/qje/qjy012Cited by 387 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Peiming Zheng, Qin Luo, Weiwei Wang et al. · 2018 · Cell Death and Disease
Abstract Tumor-associated macrophages (TAMs) are a major component of the tumor microenvironment and have been shown to contribute to tumor aggressiveness. However, the detailed mechanisms underlying the pro-metastatic effect of TAMs on gastric cancer are not clearly defined. Here, we show that TAMs are enriched in gastric cancer. TAMs are characterized by M2-polarized phenotype and promote migration of gastric cancer cells in vitro and in vivo. Furthermore, we find that M2-derived exosomes determine the TAMs-mediated pro-migratory activity. Using mass spectrometry, we identify that apolipopro
View details →DOI: 10.1038/s41419-018-0465-5Cited by 387 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Humira Sonah, Louise S. O’Donoughue, Elroy R. Cober et al. · 2014 · Plant Biotechnology Journal
Soya bean is a major source of edible oil and protein for human consumption as well as animal feed. Understanding the genetic basis of different traits in soya bean will provide important insights for improving breeding strategies for this…
View details →DOI: 10.1111/pbi.12249Cited by 387 Negative / Null Result ReportOpen accessSocial Sciences
Christopher R. Berry, Barry C. Burden, William G. Howell · 2010 · American Political Science Review
Scholarship on distributive politics focuses almost exclusively on the internal operations of Congress, paying particular attention to committees and majority parties. This article highlights the president, who has extensive opportunities,…
View details →DOI: 10.1017/s0003055410000377Cited by 387 Negative / Null Result ReportPsychology
Lynne Steinberg, Carla Sharp, Matthew S. Stanford et al. · 2012 · Psychological Assessment
The Barratt Impulsivity Scale (BIS), a 30-item self-report measure, is one of the most commonly used scales for the assessment of the personality construct of impulsiveness. It has recently marked 50 years of use in research and clinical…
View details →DOI: 10.1037/a0030550Cited by 386 Negative / Null Result ReportMaterials Science
Dimitrios Priftis, Matthew Tirrell · 2012 · Soft Matter
Mixing of oppositely charged polyelectrolytes in aqueous solutions may result in the formation of polyelectrolyte complexes (PEC). Phase separation and complex coacervation of polypeptides are investigated in this study. Polypeptides have…
View details →DOI: 10.1039/c2sm25604eCited by 385 Negative / Null Result ReportOpen accessPhysics and Astronomy
Zaven Arzoumanian, P. T. Baker, Adam Brazier et al. · 2024 · Figshare
We search for an isotropic stochastic gravitational-wave background (GWB) in the newly released 11 year data set from the North American Nanohertz Observatory for Gravitational Waves (NANOGrav). While we find no evidence for a GWB, we place constraints on a population of inspiraling supermassive black hole (SMBH) binaries, a network of decaying cosmic strings, and a primordial GWB. For the first time, we find that the GWB constraints are sensitive to the solar system ephemeris (SSE) model used and that SSE errors can mimic a GWB signal. We developed an approach that bridges systematic SSE diff
View details →DOI: 10.25916/sut.26295832.v1Cited by 385 Negative / Null Result ReportSocial Sciences
Gail Kinman, Siobhan Wray, Calista Strange · 2011 · Educational Psychology
Although teaching has been described as a profoundly emotional activity, little is known about the emotional demands faced by teachers or how this impacts on their well-being. This study examined relationships between ‘emotional labour’,…
View details →DOI: 10.1080/01443410.2011.608650Cited by 385 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Jonathan A. Hern, Asma Baig, Gregory I. Mashanov et al. · 2010 · Proceedings of the National Academy of Sciences
G-protein-coupled receptors (GPCRs) are the largest family of transmembrane signaling proteins in the human genome. Events in the GPCR signaling cascade have been well characterized, but the receptor composition and its membrane…
View details →DOI: 10.1073/pnas.0907915107Cited by 383 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Joel Atallah, Lisa Teixeira, Raul Salazar et al. · 2014 · Proceedings of the Royal Society B Biological Sciences
Evolutionary innovation can allow a species access to a new ecological niche, potentially reducing competition with closely related species. While the vast majority of Drosophila flies feed on rotting fruit and other decaying matter, and…
View details →DOI: 10.1098/rspb.2013.2840Cited by 382 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Lasse Folkersen, Eric B. Fauman, Maria Sabater‐Lleal et al. · 2017 · PLoS Genetics
Recent advances in highly multiplexed immunoassays have allowed systematic large-scale measurement of hundreds of plasma proteins in large cohort studies. In combination with genotyping, such studies offer the prospect to 1) identify mechanisms involved with regulation of protein expression in plasma, and 2) determine whether the plasma proteins are likely to be causally implicated in disease. We report here the results of genome-wide association (GWA) studies of 83 proteins considered relevant to cardiovascular disease (CVD), measured in 3,394 individuals with multiple CVD risk factors. We id
View details →DOI: 10.1371/journal.pgen.1006706Cited by 380 Negative / Null Result ReportOpen accessSocial Sciences
Davide Proserpio, Georgios Zervas · 2017 · Marketing Science
We investigate the relationship between a firm’s use of management responses and its online reputation. We focus on the hotel industry and present several findings. First, hotels are likely to start responding following a negative shock to…
View details →DOI: 10.1287/mksc.2017.1043Cited by 380 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Anushree Tandon, Amandeep Dhir, Puneet Kaur et al. · 2020 · Journal of Retailing and Consumer Services
Although consumer interest in organic food has risen over time, resulting in a generally positive attitude toward these organic food products, scholarly research suggests a comparatively low volume of its consumption in the market. This has resulted in an urgent need to study the motivations which enhance consumers’ proclivity to purchase food items produced organically. The current research attempts to understand potential associations between motivations (intrinsic and extrinsic), attitude, and buying behaviour towards organic food. Self-determination theory (SDT) was applied to develop a th
View details →DOI: 10.1016/j.jretconser.2020.102247Cited by 380 