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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21770 results · page 726 of 726

Negative / Null Result ReportMedicine

Does Communication Effectiveness Assessed by Communication Scholars Correlate with Patient Perception of Clinician Empathy?

Ponce H, Cordero R, Tran J et al. · 2025 · Journal of patient experience

In a prior study, communication scholar ratings of clinician communication effectiveness did not correlate with perceived clinician empathy, which is one aspect of patient experience. We repeated the analysis with a different rating of…

View details →DOI: 10.1177/23743735251323674
Negative / Null Result ReportOpen accessMedicine

Single-Cell and Plasma Proteomics Do Not Differentiate Patients With and Without SARS-CoV-2 Antigenemia in Convalescence in a Cohort of 100 Patients.

Pienkos S, Swank Z, Hamlin RE et al. · 2025 · Open forum infectious diseases

Plasma samples obtained approximately 3 ( n = 100) and 12 months ( n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins or single-cell protein…

View details →DOI: 10.1093/ofid/ofaf515
Negative / Null Result ReportOpen accessMedicine

Fluoroquinolones and the risk of aortic aneurysm or aortic dissection: evidence from a nationwide nested case-control study paralleled with matched experimental models.

Wesley CD, Strange JE, Holt A et al. · 2025 · European heart journal open

Aims Fluoroquinolones (FQ) have been associated with aortic aneurysm and aortic dissection (AA/AD) resulting in an official warning. Recently, large-scale epidemiological studies failed to confirm this. Methods and results The current…

View details →DOI: 10.1093/ehjopen/oeaf021
Negative / Null Result ReportOpen access

Testing the activitystat hypothesis

Physical activity has many health and psychological benefits, however many programs aimed at increasing physical activity have failed to show the expected results. This may be because when people increase their level of exercise, they…

Negative / Null Result ReportOpen accessMedicine

Use of a slow-release GnRH implant in an adult billy goat.

Demattio L, Fietz D, Schuler G et al. · 2024 · Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere

A 9.4 mg deslorelin slow-release implant was inserted into an adult, healthy billy goat to achieve temporary infertility and a reduction in sexual behavior. The implant was inserted in late autumn. No significant change in testis size was…

View details →DOI: 10.1055/a-2289-5640
Negative / Null Result ReportOpen accessAgriculture

Factors Influencing Off‑leash Dog Walking in Public Places

Michaela Sediva, Kristyna Holcova, Lenka Pillerova et al. · 2017 · Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis

Little is known about factors that influence owners’ decisions walking their dogs on or off a leash in public places. We examined the effect of the type of public place, dog’s age, sex and size, and human gender on off‑leash dog walking. Observations of 1850 dogs and their owners were made in streets and parks in Brno (Czech Republic). Multiple logistic regression analysis showed no significant effect of human gender on the frequency of unleashed dogs in streets and parks. Off‑leash dog walking was 2.8 times more likely in parks than in streets. Adult dogs were unleashed 1.9 times more likely

View details →DOI: 10.11118/actaun201765051761
Negative / Null Result ReportOpen accessAquaculture. Fisheries. Angling

Effects of selenium-enriched probiotics on growth performance, antioxidant capacity, intestinal health, and metabolism in mandarin fish (Siniperca chuatsi) juveniles

Fu liang, Ming Li, Meiling Yu et al. · 2026 · Aquaculture Reports

Abstracts: This study investigated the effects of selenium-enriched Bacillus subtilis on the growth performance, antioxidant capacity, intestinal health, and metabolism of mandarin fish (Siniperca chuatsi) juveniles. The experiment included a control group (Y), a Bacillus subtilis group (BS), an inorganic selenium group (Se), and three groups with low, medium, and high concentrations of selenium-enriched B. subtilis (S1, S2, S3) in a 30-day feeding trial. The results showed that selenium-enriched B. subtilis had no significant effect on the final average body weight or specific growth rate of

View details →DOI: 10.1016/j.aqrep.2026.103652
Negative / Null Result ReportOpen accessTechnology

Effect of Low-Temperature Conditioning of Excess Dairy Sewage Sludge with the Use of Solidified Carbon Dioxide on the Efficiency of Methane Fermentation

Joanna Kazimierowicz, Izabela Bartkowska, Maria Walery · 2020 · Energies

This study aimed to determine the effect of the low-temperature conditioning of excess dairy sewage sludge using solidified carbon dioxide on the efficiency of methane fermentation. An increase in the solidified carbon dioxide to excess dairy sewage sludge volumetric ratio above 0.3 had no significant effect on chemical oxygen demand concentration in the dissolved phase. The highest chemical oxygen demand values, ranging from 490.6 ± 12.9 to 510.5 ± 28.5 mg·dm −3 , were determined at solidified carbon dioxide to excess dairy sewage sludge ratio ranging from 0.3 to 0.5. The low-temperature cond

View details →DOI: 10.3390/en14010150
Negative / Null Result ReportOpen accessScience

The Effects of COVID-19-related Driving Restrictions on Air Quality in an Industrial City

Daulet Assanov, Aiymgul Kerimray, Birzhan Batkeyev et al. · 2021 · Aerosol and Air Quality Research

Abstract To slow the spread of COVID-19, the state of emergency was announced in Kazakhstan on March 16, 2020. Ust-Kamenogorsk instituted COVID-19 lockdown measures on April 2, 2020. The restrictions reduced the flow of traffic in the city but did not have a major impact on the large industries and power plants. In the areas with a complex profile of emission sources, traffic restriction measures alone may hardly tackle serious air pollution. This natural experiment allowed us to test how the reduction in transport movement affects air quality in Ust-Kamenogorsk, as there is a tendency to hold

View details →DOI: 10.4209/aaqr.200663
Negative / Null Result ReportOpen accessInfectious and parasitic diseases

Assessment of Recovery Time, Worsening, and Death among Inpatients and Outpatients with COVID-19, Treated with Hydroxychloroquine or Chloroquine plus Azithromycin Combination in Burkina Faso

Toussaint Rouamba, Esperance Ouédraogo, Houreratou Barry et al. · 2022 · International Journal of Infectious Diseases

Objectives: Our study aimed to assess the statistical relationship between the use of chloroquine phosphate or hydroxychloroquine plus azithromycin (CQ/HCQ + AZ) and virological recovery, disease worsening, and death among out- and inpatients with COVID-19 in Burkina Faso. Methods and Designs: This was a retrospective observational study that compared outcomes in terms of time to recovery, worsening, and death in patients who received CQ/HCQ + AZ and those who did not using a multivariable Cox or Poisson model before and after propensity matching. Results: Of the 863 patients included in the s

View details →DOI: 10.1016/j.ijid.2022.02.034
Negative / Null Result ReportOpen accessComputer Science

Temporal Adaptation of BERT and Performance on Downstream Document Classification: Insights from Social Media

Paul Röttger, Janet B. Pierrehumbert · 2021 · arXiv

Language use differs between domains and even within a domain, language use changes over time. For pre-trained language models like BERT, domain adaptation through continued pre-training has been shown to improve performance on in-domain downstream tasks. In this article, we investigate whether temporal adaptation can bring additional benefits. For this purpose, we introduce a corpus of social media comments sampled over three years. It contains unlabelled data for adaptation and evaluation on an upstream masked language modelling task as well as labelled data for fine-tuning and evaluation on

Negative / Null Result ReportOpen accessComputer Science

To SMOTE, or not to SMOTE?

Yotam Elor, Hadar Averbuch-Elor · 2022 · arXiv

Balancing the data before training a classifier is a popular technique to address the challenges of imbalanced binary classification in tabular data. Balancing is commonly achieved by duplication of minority samples or by generation of synthetic minority samples. While it is well known that balancing affects each classifier differently, most prior empirical studies did not include strong state-of-the-art (SOTA) classifiers as baselines. In this work, we are interested in understanding whether balancing is beneficial, particularly in the context of SOTA classifiers. Thus, we conduct extensive e

Negative / Null Result ReportOpen accessChemical technology

Wearable Spectroradiometer for Dosimetry

Maximilian J. Chmielinski, Martin A. Cohen, Michael G. Yost et al. · 2022 · Sensors

Available wearable dosimeters suffer from spectral mismatch during the measurement of broadband UV and visible radiation in environments that receive radiation from multiple sources emitting differing spectra. We observed this type of multi-spectra environment in all five Washington State cannabis farms visited during a field study investigating worker exposure to ultraviolet radiation in 2018. Spectroradiometers do not suffer from spectral mismatch in these environments, however, an extensive literature review conducted at the time of writing did not identify any spectroradiometers that were

View details →DOI: 10.3390/s22228829
Negative / Null Result ReportOpen accessNursing

Changes in body temperature of critically ill patients submitted to bed bathing: a crossover clinical trial

Luana Vieira Toledo, Bárbara Xavier dos Santos, Patrícia de Oliveira Salgado et al. · Revista Brasileira de Enfermagem

ABSTRACT Objectives: to compare tympanic and axillary body temperature values of critical patients before and after the traditional and dry bed bath. Methods: this is a randomized, open crossover clinical trial conducted with 50 adult critical patients. All patients received both types of bed bathing. The tympanic and axillary temperature values were measured at the beginning and end of the baths. The Wilcoxon test or paired Student’s t test was used. Results: elderly and male patients predominated. There was no significant difference between tympanic temperature medians measured during the tr

View details →DOI: 10.1590/0034-7167-2020-0969
Negative / Null Result ReportOpen accessPhysiology

Response of Vital Capacity (VC) to Multiple Repetitions of Performance and its Relation with Some Anthropometric Measurements for a Sample of Practitioners of Sports Activity

Mazen Samie Hassn · 2018 · مجلة الرافدين للعلوم الرياضية

The subject of the research focuses on identifying the differences between the three attempts to test the viability of VC and the contribution of age ratios, and some anthropometric measurements in the best bioenergy test. It also aims to adjust a regression model to predict the biological capacitance in relation to age and some anthropometric variables. The researcher hypothesizes that there are no significant differences between the three tests of the vital capacity, and that the coefficients of the regression model for linear regression equation in the biomass test are not different from ze

View details →DOI: 10.33899/rajsport.2018.163014
Negative / Null Result ReportOpen accessPlant culture

Flavonoids, chalcones and phenyl-propanoids in apple and pear flowers

Gy. Horváth, A. Farkas, Gy. L. Szabó · 2004 · International Journal of Horticultural Science

The presence of phloretin-glycosides in the hypanthium and pistil of apple and pear flowers can be verified. Thin layer chromatography is a reliable method for detecting phloretin, gained by acidic hydrolysis. The dominance of phloretin was equally characteristic for flowers in apple (`Sampion', 'Freedom') and pear (Tem-re Bosc', 'Conference') cultivars treated with various bioregulators (Biomit, Bion 50WG, Regalis), no significant difference could be found visually as compared to control samples. Chlorogenic acid and caffeic acid was detected in all apple and pear samples, rutin was present o

View details →DOI: 10.31421/ijhs/10/2/459
Negative / Null Result ReportOpen accessScience

Comparative Analysis of High-Intensity versus Low-to-Moderate Intensity Statin Therapy in Patients Undergoing Rotational Atherectomy for Calcified Coronary Artery Disease

Sang-Suk Choi, Jin Jung, Sung-Ho Her et al. · 2023 · Life

(1) Background: Moderate-intensity statin therapy, when compared to high-intensity statin therapy in Asian populations, has shown no significant difference in cardiovascular prognosis in small studies. The aim of this study was to compare the prognosis of patients based on statin intensity following rotational atherectomy (RA) during high-complexity percutaneous coronary intervention (PCI). (2) Methods: The ROCK registry, a multicenter retrospective study, included patients who had undergone rotational atherectomy (RA) during percutaneous coronary intervention (PCI) at nine tertiary medical ce

View details →DOI: 10.3390/life13112232
Negative / Null Result ReportOpen accessMedicine

Reform and exploration of the “4+4” clinical medical talent training model

LU Yongping, PAN Tingfang · 2025 · Jichu yixue yu linchuang

In order to cultivate interdisciplinary innovative medical talents who can adapt to the development of the needs of national medical care and of global file of medical education, Peking Union Medical College has initiated the project of the “4+4” model, which covers a series of education remodeling like candidate trainees’ enrollment, curriculum integration application of new teaching methods, assessment and evaluation, etc., and has made a great progress. The existing evaluation data show that there is no significant difference between the academic performance of students in the “4+4” trainin

View details →DOI: 10.16352/j.issn.1001-6325.2025.04.0551