e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21390 results · page 705 of 713

Negative / Null Result ReportOpen accessMedicine

Group-Based Medical Mistrust and Logistical Factors Influencing Rheumatology Clinical Trial Enrollment: A Single-Center Cross-Sectional Survey.

Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology

Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…

View details →DOI: 10.1002/acr2.90030
Negative / Null Result Report

Similar exercise adherence and physical fitness outcomes are observed across distinct motivation profiles in older adults participating in a home-based structured exercise programme

Munns A, Feron J, Duda J et al. · 2026 · Preprint

Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…

View details →DOI: 10.31234/osf.io/gk74p_v1
Negative / Null Result ReportMedicine

Co-Occurring Substance Use and Psychiatric Disorders in Psychiatric Emergency Services: Suicidality, Substance Use, and Treatment Utilization.

Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis

Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…

View details →DOI: 10.1080/15504263.2025.2606022
Negative / Null Result ReportMedicine

Novel measures of frontal plane knee wobbling predict anterior cruciate ligament injury in Japanese female basketball players: A prospective pilot study.

Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)

Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…

View details →DOI: 10.1016/j.clinbiomech.2026.106768
Negative / Null Result ReportMedicine

Pain, respiratory symptoms, interpretation bias and death anxiety are associated with fear of disease progression in people with asthma.

Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology

Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…

View details →DOI: 10.1111/bjhp.70050
Negative / Null Result ReportMedicine

A longitudinal study on the bidirectional association between mindfulness and insomnia: The mediating role of negative affect.

Ming X, Liu H, Yang J et al. · 2026 · Applied psychology. Health and well-being

Prior studies suggest that mindfulness interventions are viable for alleviating insomnia; however, the potential bidirectional link between mindfulness and insomnia warrants a longitudinal study. This study investigates the bidirectional…

View details →DOI: 10.1111/aphw.70123
Negative / Null Result Report

Impact of Delayed Umbilical Cord Clamping on Days of Phototherapy in Preterm Neonates 23–35 Weeks’ Gestation - A Retrospective, Single-Center Cohort Study

Yanowitz T, Patel A · 2025 · Preprint

Abstract OBJECTIVE: To evaluate whether delayed cord clamping (DCC) duration predicts hyperbilirubinemia and phototherapy days among preterm infants of different gestational ages. STUDY DESIGN: In this retrospective cohort study, 2,421…

View details →DOI: 10.21203/rs.3.rs-8158705/v1
Negative / Null Result ReportOpen accessMedicine

Prognostic value of magnetic resonance imaging in pediatric-onset primary sclerosing cholangitis.

Vanhanen EJ, Lehtimäki TE, Kolho KL et al. · 2026 · Therapeutic advances in gastroenterology

Background The prognostic value of magnetic resonance imaging (MRI) in pediatric-onset primary sclerosing cholangitis (PSC) remains poorly studied. The MRI-based ANALI scores with and without gadolinium (ANALI Gd and ANALI NoGd ) have…

View details →DOI: 10.1177/17562848261426258
Negative / Null Result ReportMedicine

Sex-Specific Prognostic Patterns of Sarcopenia Components in Patients With Heart Failure.

Habaguchi A, Katano S, Yano T et al. · 2026 · Circulation journal : official journal of the Japanese Circulation Society

Background Whether the components of sarcopenia provide sex-specific prognostic information in heart failure (HF) remains uncertain. Methods and results We enrolled 604 patients with HF (259 women; median age, 73 years) undergoing…

View details →DOI: 10.1253/circj.cj-25-0714
Negative / Null Result Report

Psychology at the screen: The flaws of the current VAR protocol

Walker D, Staniforth CE, Thomas J et al. · 2025 · Preprint

The English Premier League claim that the introduction of the Video Assistant Referee (VAR) has led to more correct decisions. However, the psychological mechanisms of the current protocol have yet to be explored, and the current study…

View details →DOI: 10.31234/osf.io/jgcbw_v2
Negative / Null Result Report

The Bidirectional Relationship Between Sleep Disturbance and Exposure-Based Treatment for Social Anxiety Disorder: A Multi-Method Examination

McGrory CM, Fireman GD, Bottary RM et al. · 2025 · Preprint

Abstract Background . Individuals with Social Anxiety Disorder (SAD) often experience poor sleep, which may influence treatment outcomes. Although theoretical models link sleep and fear extinction mechanisms, findings are equivocal and…

View details →DOI: 10.21203/rs.3.rs-7121721/v1
Negative / Null Result ReportMedicine

Examining links between somatosensation and cognition in children with hemiplegic cerebral palsy.

Hewitt KM, Bayliss DM, McLean BA et al. · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While…

View details →DOI: 10.1080/09297049.2026.2621691
Negative / Null Result ReportOpen accessMedicine

Does Bone Quality Predict Pseudarthrosis, Subsidence, or Loss of Lordosis After Anterior Cervical Discectomy and Fusion? Minimum 5-Year Cohort Study.

Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal

Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…

View details →DOI: 10.1177/21925682261424749
Negative / Null Result ReportMedicine

Chicken or the egg: The relationship between cognitive deficits and negative symptoms in first episode psychosis.

Au-Yeung C, Christophe NK, Lavigne KM et al. · 2026 · Schizophrenia research

Background Cognitive impairments and negative symptoms (NS) represent an unmet therapeutic need in psychotic disorders. Both NS and cognitive impairments, are key predictors of functioning. Both also appear during the illness prodrome,…

View details →DOI: 10.1016/j.schres.2026.02.008
Negative / Null Result Report

Social Attunement and Alcohol Use: The Role of Age and Gender

Romein C, Colyer-Patel K, Kroon E et al. · 2025 · Preprint

Background: Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…

View details →DOI: 10.31234/osf.io/srk3e_v2
Negative / Null Result Report

The time course of neural activity predictive of self-initiated movement

Jeay-Bizot L, Basbug M, Maoz U et al. · 2025 · Preprint

Decades of research have shown that early ramping activity is a very reliable antecedent of self-initiated movement. However, the dominant paradigm has been to only analyze data epochs culminating in movement, which discounts how often…

View details →DOI: 10.31234/osf.io/vdbg8_v3
Negative / Null Result Report

Cannabis Use, Affect, and Emotion Regulation in Daily Life: A 3-Week Experience Sampling Method Study in People Who Smoke Cannabis Almost Daily

Donate APG, Cousijn J, Kroon E et al. · 2026 · Preprint

Background and Aims: Although many people who use cannabis report mood-enhancing effects, affective responses are thought to vary within and between individuals. This study examined the bidirectional associations between momentary affect…

View details →DOI: 10.31234/osf.io/w5fd3_v1
Negative / Null Result ReportMedicine

On how people describe paintings with mirrors.

Bertamini M, Lucia M, Diaz S et al. · 2025 · British journal of psychology (London, England : 1953)

Since antiquity humans have been fascinated by mirrors; yet, when asked to predict what is made visible in the reflection, or to interpret a scene with a mirror, observers make systematic errors. Many observers claim that a character in a…

View details →DOI: 10.1111/bjop.70042
Negative / Null Result Report

Dynamics of Torque Teno Virus DNA Load in Bronchoalveolar Lavage in COVID-19 associated Acute Respiratory Distress Syndrome

Bumberger AM, Kastner M, Rüsing L et al. · 2026 · Preprint

Background: Torque teno virus (TTV) DNA load has been proposed as a surrogate marker of the net state of immunosuppression. While plasma TTV levels have been associated with infection risk and adverse outcomes, the clinical relevance of…

View details →DOI: 10.22541/au.176770094.44860022/v1
Negative / Null Result Report

Predicting AI Anxiety: An Existential Perspective

Gobet F, Evans N, Chatfield-Jouin F et al. · 2025 · Preprint

Artificial Intelligence (AI) is transforming many aspects of daily life and improving efficiency and outcomes in various sectors, ranging from healthcare to education. However, this rapid integration also introduces significant anxiety…

View details →DOI: 10.31234/osf.io/h7zje_v1
Negative / Null Result ReportMedicine

Patient-reported levels of pain and itch in hypertrophic scar before and after fractional ablative laser treatment.

Carreras JP, Carney BC, Lee D et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association

Skin fibrosis, especially hypertrophic scars (HTS), remains understudied with few effective treatments. Studying HTS is challenging due to its natural tendency to improve over time, making it hard to separate intervention effects. This…

View details →DOI: 10.1093/jbcr/irag012
Negative / Null Result ReportMedicine

Associations of spirituality and craving among individuals in substance use disorder treatment: A latent change score modeling approach.

Rabinowitz JA, Masyn K, Thomas N et al. · 2026 · Drug and alcohol dependence

Objective Using a latent change score modeling approach, we tested the bidirectional relationships between spirituality and craving during the first month of substance use disorder (SUD) treatment. Specifically, we examined whether higher…

View details →DOI: 10.1016/j.drugalcdep.2026.113116
Negative / Null Result ReportMedicine

Evaluating day +90 donor chimerism as a prognostic marker of clinical outcomes among allogeneic hematopoietic cell transplant recipients who received myeloablative conditioning.

Jubas S, Collins K, Obara K et al. · 2026 · Transplantation and cellular therapy

Background Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for hematologic malignancies. However, relationships between donor chimerism and clinical outcomes remain poorly characterized. Objective The…

View details →DOI: 10.1016/j.jtct.2026.06.024