A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
422 results in Replication Failure · page 7 of 15
Mølhave M, Olsen ZL, Svanesøe S et al. · 2025 · Acta oto-laryngologica
Background Tracheostomy is widely used in critically ill patients, yet limited clinical data exist from Danish ENT departments. Aims/objectives To describe clinical outcomes and perioperative care in patients undergoing tracheostomy at a…
Oreskovic NM, Erwin AE, Allon ZA et al. · 2026 · The American journal of managed care
Objectives Office-based care coordination programs are increasingly utilizing social work-trained care coordinators to manage high-cost, high-need (HCHN) patients with increased psychosocial risk, including patients covered by Medicaid.…
Ela Miranda, Iriani Iriani, I. Nasution · 2022 · JRMB (Jurnal Riset Manajemen & Bisnis)
The high income tax expense causes the company to carry out earnings management. Decreased earnings management tends to result in high tax planning. The company's ability to pay off short-term liabilities by using good current assets…
Elsiaulavita Gracia, S. Nurohman, I. Wilujeng · 2024 · Jurnal Penelitian Pendidikan IPA
This study aims to analyze the impact of applying the STEAM (Science, Technology, Engineering, Arts, Mathematics) approach in science education on students' creative thinking skills. The STEAM approach offers an integration of various…
Magno Serrano P, Barros P, Dores M et al. · 2026 · Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
Introduction Antibiotic resistance represents a major public health problem driven by inappropriate antimicrobial use. Cystoscopy is a common urological procedure associated with a low risk of urinary tract infection (UTI), and the role of…
Khadanga S, Yant B, Savage PD et al. · 2026 · Journal of cardiopulmonary rehabilitation and prevention
Purpose Despite the benefits, cardiac rehabilitation (CR) is underutilized, particularly in women. Case management (CM) has been shown to reduce the risk of cardiovascular disease and improve health outcomes. The purpose of this study was…
Takeda Y, Nakai T, Okamoto T et al. · 2026 · The Journal of arthroplasty
Background Mirogabalin, a selective α2δ-1 ligand, has been proposed to exhibit potent analgesic effects with fewer central nervous system (CNS) side effects than prior gabapentinoids. Its effectiveness for acute postoperative pain after…
He Z, Lyu S, Huang M et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
Objective: To investigate the expression of HPV 6/11 in NIP tissues and evaluate the adjuvant therapeutic effect of interferon-α gel on HPV-positive NIP patients. Methods: Forty-two newly diagnosed Nasal Inverted Papilloma（NIP） patients…
Shibasaki S, Endo H, Yamamoto H et al. · 2026 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Objective To evaluate contemporary short-term outcomes of robotic gastrectomy (RG) approximately 5 years after its widespread implementation, compared with laparoscopic gastrectomy (LG) using a nationwide Japanese database. Background RG…
Franco-Ortega JA, Albertos-Alpuche PJ, Mora-Medina P et al. · 2026 · Journal of fish diseases
Immersion anaesthesia is widely used in fish handling and research, yet optimization of protocols requires not only effective immobilization but also consideration of internal physiological responses. This study evaluated the effects of…
A. Bühler, Johannes Thrul, Evelin Strüber et al. · 2015 · Health Promotion International
Because of scarce research, the effectiveness of substance abuse prevention in leisure settings remains unclear. In this study, we evaluated the effectiveness of a peer-led educational prevention measure with adolescent groups in…
Küçükatalay Ö, Kantarcı S, Dağlı U et al. · 2026 · JSLS : Journal of the Society of Laparoendoscopic Surgeons
Introduction Total laparoscopic hysterectomy (TLH) is widely performed for benign gynecologic conditions; however, postoperative pain particularly shoulder pain related to residual intraperitoneal CO 2 remains a clinical concern. This…
Meerman M, Buijser M, Neto AS et al. · 2026 · Critical care medicine
Objectives To determine whether perioperative IV magnesium sulfate infusion, targeting serum magnesium concentrations of 1.5-2.0 mmol/L, reduces the incidence of postoperative atrial fibrillation (POAF) in patients undergoing cardiac…
Liang XQ, Han L, Yan T et al. · 2026 · Journal of anesthesia
Purpose Postoperative pulmonary complications are common and associated with worse long-term outcomes. In our previous trial, prophylactic penehyclidine inhalation reduced pulmonary complications in high-risk patients. Herein, we tested…
Wanqing Huang, Jiuxu Bai, Yanping Zhang et al. · 2024 · Renal Failure
Background Elderly hemodialysis (HD) patients have a high risk of death. The effect of different types of HD membranes on survival is still controversial. The purpose of this study was to determine the relationship between the use of low-flux or high-flux membranes and all-cause and cardiovascular mortality in elderly hemodialysis patients.Methods This was a retrospective clinical study involving maintenance hemodialysis patients which were categorized into low-flux and high-flux groups according to the dialyzer they were using. Propensity score matching was used to balance the baseline data o
Awwad A, Das Adhikari U, Burdo TH et al. · 2026 · AIDS (London, England)
Objective To determine whether pitavastatin reduces enterocyte injury, assessed by intestinal fatty acid-binding protein (I-FABP), among antiretroviral therapy-treated people with HIV (PWH) enrolled in the REPRIEVE mechanistic substudy.…
Elenjickal EJ, Mavrakanas TA · 2026 · American journal of nephrology
Background Aldosterone regulates genes controlling fluid and electrolyte balance through mineralocorticoid receptor (MR) activation. Sustained MR activation promotes inflammation, fibrosis, sodium retention, and myocardial remodeling. MR…
Aitken D, Cai G, Hill CL et al. · 2026 · JAMA internal medicine
Importance Knee osteoarthritis (OA) is disabling, with few effective treatments. Anti-inflammatory treatments may be effective for patients with an inflammatory phenotype. Objectives To evaluate the efficacy of the interleukin-1β blocker…
Alallah J, Mohtisham F, Ahmed A et al. · 2026 · Journal of neonatal-perinatal medicine
BackgroundThe study examined the medical impact of tahneek with dates on hypoglycemia in high-risk newborns. Tahneek, an Islamic tradition, may offer benefits such as stimulating mouth muscles and aiding in breastfeeding initiation. The…
Hoenle A, Rickert D, Steinhart H et al. · 2026 · The Journal of laryngology and otology
Objectives. To determine whether sex independently predicts survival in oropharyngeal squamous cell carcinoma and whether human papillomavirus status mediates apparent sex-related survival differences at the population level. Methods.…
Gangeri L, Alfieri S, Anselmi V et al. · 2025 · Tumori
Background As part of the improvement plan of the Organisation of European Cancer Institutes at the Fondazione IRCCS Istituto Nazionale dei Tumori of Milan (INT) a Committee composed of patients, caregivers, and representatives of patient…
Suhendy CCV, Koeser AK, Klein RW et al. · 2026 · Preprint
Urban parks are widely recognized for their mental health benefits, especially among frequent visitors. However, the factors underlying regular park use among older urban residents remain poorly understood. This study examined park…
Anum Zahra, Maarten van Smeden, Petra J. M. Elders et al. · 2025 · BMC Geriatrics
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vulnerability in this frail population. However, the prognostic value of these cumulative comorbidity scores like the Charlson comorbidity index (CCI) remained unclear in this population. We evaluated the incremental predictive value of the CCI for predicting 28-day mortality in NH residents with COVID-19, compared to prediction using age and sex only. Methods
Stepanovic Z, Ristic B, Matic A et al. · 2026 · Journal of clinical medicine
Background : The optimal route of tranexamic acid (TXA) administration remains one of the most debated topics in total knee arthroplasty. This study aimed to compare the effects of intravenous (IV), intra-articular (IA), and combined TXA…
Shibata K, Yamaguchi T, Takizawa K et al. · 2026 · Journal of strength and conditioning research
Abstract Shibata, K, Yamaguchi, T, Takizawa, K, and Nosaka, K. Comparison between eccentric-concentric and eccentric-only (ECC-only) dumbbell arm curl exercise for the number of repetitions to failure over five sets. J Strength Cond Res…
Li N, Huang H, Jia Y et al. · 2026 · Clinical rheumatology
Objectives To explore the risk of relapse after glucocorticoids (GCs) withdrawal in patients with stable Sjögren's disease-associated interstitial lung disease (SjD-ILD). Methods This was a single-center, retrospective cohort study…
Ye C, Sheng Y, Zhang X et al. · 2026 · Plant Science.
Gene editing has emerged as a powerful tool in crop breeding, particularly for rice, enabling the creation of germplasm and trait improvement. A thorough understanding of gene functions is essential for precise and efficient crop…
Medeiros CNA, Azevedo IG, Gomes Fernandes SG et al. · 2026 · PeerJ
Background Urinary incontinence (UI) is a common complaint among middle-aged and older women, associated with many negative impacts in health. The aim of this study was to analyze whether an association exists between UI and sarcopenic…
Tidblad L, Öberg Sysojev A, Delcoigne B et al. · 2025 · RMD open
Objective To examine whether obesity and/or overweight are independently associated with an increased risk of remission failure in patients with early rheumatoid arthritis (RA), treated with methotrexate as first disease-modifying…
Alevi KCC, Ravazi A, de Oliveira J et al. · 2025 · Scientific reports
The diversification of Rhodnius species has been primarily attributed to vicariance events. Phylogenomic studies have proposed various evolutionary hypotheses - such as incomplete lineage sorting, hybrid speciation, and introgression - to…