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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21770 results · page 699 of 726

Negative / Null Result ReportMedicine

Preferences for Gender Stereotypicality in Artificial Intelligence: Existence, Comparison to Human Biases, and Implications for Choice.

Spielmann J, Stern C · 2026 · Personality & social psychology bulletin

Do people prefer that artificial intelligence (AI) aligns with gender stereotypes when requesting help to answer a question? We found that people preferred gender stereotypicality (over counterstereotypicality and androgyny) in voice-based…

View details →DOI: 10.1177/01461672241307276
Failed Experiment ReportMedicine

Optimizing Genome Editing in Mollusks (<i>Crassostrea gigas</i>) <i>in Vitro</i> Validation of sgRNA and Identifying Key Factors Influencing Efficiency.

Li Q, Yu H, Du S et al. · 2025 · The CRISPR journal

CRISPR-Cas9 genome editing holds tremendous potential for accelerating genetic improvements in aquaculture. The success of the CRISPR-Cas9 system relies on the specificity and efficiency of engineered single-guide RNAs (sgRNAs). In this…

View details →DOI: 10.1089/crispr.2024.0086
Negative / Null Result ReportMedicine

Are Elaeagnus umbellata invasions limited by microbial mutualists?

Leverette CA, Meiners SJ · 2025 · Biol Invasions.

Mutualistic interactions with soil microbes are a key component of plant invasions. Mutualists such as Rhizobia bacteria often limit invasive plant establishment and performance, but the role of nitrogen-fixing Frankia bacteria in…

View details →DOI: 10.1007/s10530-024-03456-6
Negative / Null Result ReportMedicine

Disentangling the effects of environmental and anthropogenic drivers on fungal fruitbody and spore diversity in a Mediterranean coniferous forest.

Centenaro G, Ponce Á, de-Miguel S et al. · 2025 · Journal of environmental management

Wild macrofungal species are important non-wood forest products in Mediterranean forests, where their ability to release and disperse spores is crucial for completing their life cycle. However, the ecological drivers behind fruitbody…

View details →DOI: 10.1016/j.jenvman.2025.125897
Negative / Null Result ReportMedicine

Earth's record-high greenness and its attributions in 2020

Zhang Y, Mao J, Sun G et al. · 2025 · Remote Sensing of Environment

Terrestrial vegetation is a crucial component of Earth's biosphere, regulating global carbon and water cycles and contributing to human welfare. Despite an overall greening trend, terrestrial vegetation exhibits a significant inter-annual…

Negative / Null Result ReportOpen accessMedicine

Spurious effects in random-intercept cross-lagged panel models: Results from simulations and reanalyses of data on self-esteem and problematic eating behaviors used by Beckers et al. (2023).

Sorjonen K, Nilsonne G, Ghaderi A et al. · 2026 · PloS one

The random-intercept cross-lagged panel model (RI-CLPM) is an extension of the traditional cross-lagged panel model. The RI-CPLM specifically addresses prospective effects within individuals. In the present simulations, we found that the…

View details →DOI: 10.1371/journal.pone.0351302
Negative / Null Result Report

Leaf nutrient resorption efficiency is related to leaf economic spectrum but not root economic spectrum in a tropical mangrove forest

Jiang D, Nie T, He Q et al. · 2024 · Preprint

not-yet-known not-yet-known not-yet-known unknown Leaf nutrient resorption efficiency (NuRE) serves as a metric for delineating plant strategies that range from ‘slow-fast’ performance to conservative-acquisitive resource management.…

View details →DOI: 10.22541/au.173269104.41827173/v1
Negative / Null Result ReportMedicine

Soil aggregation alterations under soil microplastic and biochar addition and aging process.

Li H, Yang L, Luo C et al. · 2025 · Environmental pollution (Barking, Essex : 1987)

Soil microplastics (MPs) are a substantial threat to soil health, particularly by disrupting soil aggregation. Additionally, MPs undergo aging processes in the soil, which may significantly alter their long-term impacts on soil structure.…

View details →DOI: 10.1016/j.envpol.2025.125655
Negative / Null Result ReportMedicine

Are horned cows in loose housing more stressed than hornless cows? a cross-sectional study in organic dairy farms.

Ebinghaus A, Thiessen G, Ivemeyer S et al. · 2025 · Animal : an international journal of animal bioscience

In commercial dairy farming, the majority of cows are dehorned or genetically hornless. It is argued that this reduces the risk of injurious and stressful social conflicts. On the other hand, in horned herds, management and housing may be…

View details →DOI: 10.1016/j.animal.2024.101405
Negative / Null Result ReportOpen accessMedicine

Sport fans' self-esteem and supporting the team that won over the favorite.

Takemura E, Matsuoka H · 2026 · Frontiers in sports and active living

Research purpose Most often, when their favorite team loses, sports fans are disappointed by the outcome and hostile to the winning team. However, in the tournaments, they also sometimes voice their support for the team that eliminated…

View details →DOI: 10.3389/fspor.2026.1810401
Negative / Null Result ReportMedicine

Are perceptions of the psychotherapist affected by the audiovisual quality of a teletherapy session?

Glasgow OG, Berman JS · 2025 · Psychotherapy research : journal of the Society for Psychotherapy Research

Objective Remote forms of psychotherapy became more common during the COVID-19 pandemic, increasing the importance of understanding how technological factors might affect remote treatment. Past research on other modes of communication…

View details →DOI: 10.1080/10503307.2024.2429010
Negative / Null Result ReportOpen accessMedicine

Masked and elusive: congruency fails in video-to-photo face matching.

Sagana A, Zhang M, Bekemeier L et al. · 2026 · Cognitive research: principles and implications

Recognizing masked perpetrators in real-world surveillance scenarios poses significant challenges due to facial occlusion and degraded image quality. This study investigated the effects of contextual congruency on matching surveillance…

View details →DOI: 10.1186/s41235-026-00712-2
Negative / Null Result ReportMedicine

Limited association between central pain processing and clinical outcomes in non-specific chronic neck pain after a manual therapy intervention: A secondary analysis.

Zabala-Mata J, Azkue JJ, Bialosky JE et al. · 2025 · Musculoskeletal science & practice

Background Non-specific chronic neck pain (NSCNP) is a prevalent condition causing significant disability. While manual therapy is recommended, its clinical benefits are limited. The relationship between central pain processing and…

View details →DOI: 10.1016/j.msksp.2025.103323
Negative / Null Result ReportMedicine

The impact of reducing cognitive load in RT and P300 concealed information tests with importance related fillers.

Wojciechowski J, Olson JM, Subramanian G et al. · 2025 · International journal of psychophysiology : official journal of the International Organization of Psychophysiology

Lukács et al. (2017) enhanced the Reaction Time Concealed Information Test (RT CIT) by incorporating "filler" items. Fillers are intended to increase attention and cognitive load, which should potentially enhance the P300 based CIT…

View details →DOI: 10.1016/j.ijpsycho.2025.112507
Negative / Null Result ReportMedicine

Positive Body Image in Adolescence: Longitudinal Associations With Identity and Eating Disorder Symptoms.

Uyar A, Vankerckhoven L, Claes L et al. · 2025 · Journal of youth and adolescence

Developmental research has mostly focused on negative body image, somewhat neglecting the role positive body image plays in adolescent development. To fill this gap, the present longitudinal study investigated the directionality of effects…

View details →DOI: 10.1007/s10964-024-02121-4
Negative / Null Result ReportOpen accessMedicine

The impact of frailty on cognitive outcomes in elderly patients with post-stroke subjective cognitive complaints.

Duan J, Zhang Y, Jin X et al. · 2025 · Frontiers in neurology

Background and purpose Frailty delineates a state of poor health characterized by the accumulation of age-related health deficits, and was associated with cognitive decline in patients with subjective cognitive complaints (SCC). However,…

View details →DOI: 10.3389/fneur.2025.1701866