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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 655 of 725

Negative / Null Result ReportMedicine

The relationship between smoking and clinical outcome in ischemic stroke patients undergoing reperfusion therapy.

Kömürcü HF, Sever N, Gökdereli NS et al. · 2025 · Neurological research

Background It has been suggested that smokers have higher recanalization rate, lower risk of cerebral hemorrhage and better prognosis than non-smokers (smoking paradox) after reperfusion therapy in patients with acute ischemic stroke (IS).…

View details →DOI: 10.1080/01616412.2024.2448628
Negative / Null Result ReportMedicine

Behavior of Listeria monocytogenes in commercial queso fresco and queso cotija and investigation of salt concentration as a control factor

Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science

Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…

Negative / Null Result ReportOpen accessMedicine

Adolescent Exposure to Nicotine and Ethanol Attenuates Adult Nicotine Reward Sensitivity in Rats.

Toyoshima M, Toyofuku R, Shimoda S et al. · 2026 · Neuropsychopharmacology reports

Adolescence is a sensitive developmental stage in which exposure to addictive substances can produce long-lasting changes in the neural circuits that regulate reward. Nicotine and ethanol are frequently co-used among adolescents, and…

View details →DOI: 10.1002/npr2.70132
Negative / Null Result ReportOpen accessMedicine

An Occurrence of Mass Psychogenic Illness: LeRoy, New York.

McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology

Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…

View details →DOI: 10.1177/08830738251369759
Negative / Null Result ReportMedicine

Presence and potential impact of anthropogenic nesting materials on a colonial breeding waterbird.

Ferreira HRS, Hadden AC, Champagnon J et al. · 2025 · The Science of the total environment

Despite the vital importance of wetlands globally, these habitats have increasingly received anthropogenic materials, such as plastics, which can impact the wildlife these habitats support. Despite commonly found in the nests of Eurasian…

View details →DOI: 10.1016/j.scitotenv.2025.178588
Negative / Null Result ReportOpen accessMedicine

Do ChatGPT and Gemini provide accurate answers to patient questions about glenohumeral arthritis?

Ohlsen SM, Pirkle SB, Yang J et al. · 2026 · JSES reviews, reports, and techniques

Background Machine learning, a subset of artificial intelligence, enables large language models (LLMs) like ChatGPT and Gemini to analyze data, learn from context, and generate responses without explicit programming. While machine learning…

View details →DOI: 10.1016/j.xrrt.2026.100715
Negative / Null Result ReportMedicine

Thrombectomy in Stroke Patients with Large Vessel Occlusion and Mild Symptoms: Insights from a Multicenter Observational Study.

Qiu K, Hang Y, Lv P et al. · 2025 · Translational stroke research

To evaluate whether endovascular thrombectomy (EVT) combined with best medical management (BMM) is more effective than BMM alone in treating mild stroke patients (National Institutes of Health Stroke Scale score pri ) group and the primary…

View details →DOI: 10.1007/s12975-025-01337-1
Negative / Null Result ReportOpen accessMedicine

Psoas muscle variables and adjuvant chemotherapy-related and survival outcomes following pancreaticoduodenectomy for periampullary malignancy.

Hajibandeh S, Hajibandeh S, Mckittrick H et al. · 2026 · World journal of gastrointestinal surgery

Background Early skeletal muscle wasting has been demonstrated to be associated with chemotherapy-related toxicity in patients with cancer. Hounsfield unit average calculation (HUAC) or psoas muscle index (PMI) can be used to diagnose…

View details →DOI: 10.4240/wjgs.v18.i2.114743
Negative / Null Result ReportMedicine

Variation in song structure does not predict associative learning performance in zebra finches (Taeniopygia castanotis) raised under controlled cultural conditions.

Derégnaucourt S, Le Maguer L, Geberzahn N · 2026 · Animal cognition

Vocal learning in songbirds requires the integration of auditory perception, sensorimotor learning, and performance monitoring, yet its relationship to general cognitive abilities remains unclear. We tested whether interindividual…

View details →DOI: 10.1007/s10071-026-02077-x
Negative / Null Result ReportMedicine

Predictors and Outcomes of Online Health Information Avoidance in the Context of COVID-19: Application and Extension of the PRIA Model.

Guan M, Yang Q, Carey P et al. · 2026 · Health communication

Despite its significant implications for public health and individual decision-making, research on information avoidance remains limited. In this study, we applied and extended the model of planned risk information avoidance (PRIA) to…

View details →DOI: 10.1080/10410236.2026.2678930
Negative / Null Result ReportMedicine

Prenatal and adolescent exposure to metals/metalloids and telomere dynamics at 14 years: Evidence from the Chitwan birth cohort.

Wai KM, Parajuli RP, Umezaki M · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Telomeres are repetitive non-coding DNA sequences at chromosome ends that progressively shorten with each cell division, serving as markers of cellular aging. Recent studies have suggested that prenatal and postnatal exposure to…

View details →DOI: 10.1016/j.jtemb.2026.127856
Replication Failure

Perspective taking predicts acute psychiatric treatment trajectories

Foley E, Bockhorst JL, Beard C et al. · 2026 · Preprint

Objective: Although perspective taking is a well-established transdiagnostic feature of psychopathology, less is known about its role in treatment outcomes. The present study examined whether perspective taking frequency upon admission to…

View details →DOI: 10.31234/osf.io/5w9g8_v1
Replication FailureMedicine

Eating your emotions: Within-person relations of emotional overeating with lability/negativity and emotion regulation from childhood to young adulthood.

Parisi F, Steinsbekk S, Wichstrøm L et al. · 2026 · Child development

Emotional overeating theories posit that lability/negativity and poor emotion regulation increase emotional overeating risk, yet empirical evidence is limited. This longitudinal study followed 878 Norwegian participants (50.1% girls)…

View details →DOI: 10.1093/chidev/aacag104
Negative / Null Result ReportMedicine

Posttraumatic cognitions and PTSD symptom change in massed prolonged exposure: The impact of treatment delivery on mechanisms of change.

Burton M, Haft S, Fiskeaux M et al. · 2026 · Journal of anxiety disorders

Background Prolonged Exposure (PE) is an effective treatment for PTSD and clarification of mechanisms of change can inform training and continued improvements. Posttraumatic cognitions have been shown to predict subsequent symptom change…

View details →DOI: 10.1016/j.janxdis.2026.103186
Negative / Null Result ReportMedicine

Thalamic Volume Asymmetry as a Potential Predictor of Vagus Nerve Stimulation Outcomes in Refractory Epilepsy.

Ujihara M, Kawabori M, Nakajima M et al. · 2026 · Neurologia medico-chirurgica

Vagus nerve stimulation is an established treatment for refractory epilepsy, but predictors of treatment response remain unclear. Given that left-sided vagus nerve stimulation preferentially modulates the left thalamus and that epileptic…

View details →DOI: 10.2176/jns-nmc.2025-0409
Negative / Null Result ReportMedicine

Longitudinal profiles of parental self- and child-focused emotion regulation.

Jordan G, Stockinger K, Schiltz C et al. · 2026 · Communications psychology

Parenting is an emotion-eliciting experience that requires parents to navigate the dual demands of regulating their own and their children's emotions, drawing on regulatory strategies such as reappraisal and rumination. However, patterns…

View details →DOI: 10.1038/s44271-026-00469-w
Negative / Null Result ReportMedicine

Assessing Knowledge About Living Kidney Donation Among Transplant Candidates and Relationship to Seeking a Living Donor.

Werenski H, Stratta R, McCracken E et al. · 2026 · Clinical transplantation

Introduction Despite well-established advantages of living-donor kidney transplantation (LDKT), LDKT growth has stagnated. Barriers to seeking a living donor include insufficient knowledge among candidates and discomfort discussing LDKT.…

View details →DOI: 10.1111/ctr.70591