e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 653 of 725

Negative / Null Result ReportMedicine

The urge to fill the void: Emptiness, impulsivity, and mentalizing in the daily life of individuals with borderline personality disorder.

Sheena-Peer L, Rafaeli E, Berenson KR et al. · 2025 · Personality disorders

Emptiness is central to borderline personality disorder (BPD), significantly impacts quality of life, and is associated with increased impulsivity. Nevertheless, studies of emptiness in daily life are scarce and little is known about…

View details →DOI: 10.1037/per0000721
Negative / Null Result ReportMedicine

Industry Interactions at Medical Conferences: Representatives' Credentials and the Disclosure of Data Limitations Influence Clinician Perceptions.

O'Donoghue AC, Aikin KJ, Amoozegar JB et al. · 2025 · Journal of the American Board of Family Medicine : JABFM

Purpose Exhibit hall booths at medical conferences are a key avenue for promoting prescription drugs to health care providers (HCPs). Because HCPs spend considerable time interacting with industry representatives at conferences, we…

View details →DOI: 10.3122/jabfm.2024.240368r1
Negative / Null Result ReportMedicine

Should Communication Campaigns Promoting Vaccination Address Misinformation Beliefs? Implications from a Nationally Representative Longitudinal Survey Study among U.S. Adults.

Clark D, Kikut-Stein A, Jesch E et al. · 2024 · Journal of health communication

Public health communication campaign planners must carefully consider whether misinformation beliefs are important to target and, ideally, correct. Guided by the reasoned action approach, we hypothesized that behavior-specific beliefs…

View details →DOI: 10.1080/10810730.2024.2331488
Negative / Null Result ReportOpen accessMedicine

Social working memory in adolescence.

Grunewald K, Andrews JL, Schweizer S · 2026 · Child development

Little is known about how social network associations are tracked in cognition during adolescence, when social networks change in size and complexity. In 2023, 123 ethnically diverse adolescents and emerging adults (13-24 years; 52.9%…

View details →DOI: 10.1093/chidev/aacaf039
Negative / Null Result ReportOpen accessMedicine

Environmental Supports, Expectations, and Barriers to Leisure-Time Physical Activity During Pregnancy: A Rural-Urban Comparison.

Rogers CW, Crisp A, Wilhite K et al. · 2026 · The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

Background Physical activity (PA) during pregnancy has well-documented benefits, yet pregnant rural residents may face additional barriers to PA. Objective To examine whether leisure-time physical activity (LTPA) and correlates of LTPA,…

View details →DOI: 10.1111/jrh.70166
Negative / Null Result ReportMedicine

Cardiac autonomic function in young, healthy adults: Influence of race and sex.

Taherzadeh Z, Kissell CE, Young BE et al. · 2025 · American journal of physiology. Regulatory, integrative and comparative physiology

Non-Hispanic Black (BL) adults living in the United States are more likely to develop cardiovascular disease (CVD) compared with their non-Hispanic White (WH) counterparts. Although measures of cardiac autonomic function [i.e., spontaneous…

View details →DOI: 10.1152/ajpregu.00288.2024
Negative / Null Result ReportOpen accessMedicine

Specific Association Patterns Between Brain Glutathione Levels, Myelination, and Functional Connectivity in Adults With Autism Spectrum Disorder.

Iwabuchi T, Hirai T, Umeda N et al. · 2025 · Autism research : official journal of the International Society for Autism Research

Recent studies have implicated oxidative stress in the pathophysiology of autism spectrum disorder (ASD). Postmortem brain studies have revealed decreased levels of the reduced form of glutathione (GSH), an important antioxidant, in some…

View details →DOI: 10.1002/aur.70134
Negative / Null Result ReportOpen accessMedicine

Psychotic-Like Experiences and White Matter Microstructure: A Fixel-Based Analysis Approach With Robust Replication Across Two Cohorts.

Goodwin I, Larsen KM, Sangchooli A et al. · 2025 · Human brain mapping

Structural deficits in white matter fibre have been linked to psychosis. However, it remains unclear whether these aberrations are present in individuals that experience non-clinical psychotic-like experiences, predating illness onset.…

View details →DOI: 10.1002/hbm.70414
Negative / Null Result ReportMedicine

Outcomes and performance following posteromedial elbow débridement in Major League Baseball players.

Wollenman CC, Davis PJ, Lane GC et al. · 2024 · Journal of shoulder and elbow surgery

Background Overhead athletes are particularly susceptible to elbow valgus extension overload syndrome and development of pathologic changes in the posteromedial elbow. Though arthroscopic débridement/osteophyte resection is frequently…

View details →DOI: 10.1016/j.jse.2024.05.035
Negative / Null Result ReportMedicine

Effects of Naltrexone on Sleep Quality and Periodic Breathing at High Altitude.

Foster K, Anholm JD, Foster G et al. · 2025 · High altitude medicine & biology

Foster, Katharine, James D. Anholm, Gary Foster, Suman Thapamagar, and Prajan Subedi. Effects of naltrexone on sleep quality and periodic breathing at high altitude. High Alt Med Biol. 26:13-19, 2025. Objective: This study examined the…

View details →DOI: 10.1089/ham.2024.0023
Negative / Null Result ReportOpen accessMedicine

Breath-Holding Maneuvers and Airway Closure in Healthy Adults and Parkinson's Disease: Effects of Maneuver Type, Health Status, and Vocal Fold Bowing.

Curtis JA, Beam AB, Nam J et al. · 2025 · Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)

Introduction Breath-holding maneuvers are frequently used to improve airway closure and swallowing safety in people with dysphagia. While their effects on airway closure have been studied in healthy adults, little is known about their…

View details →DOI: 10.1159/000550088
Negative / Null Result ReportOpen accessMedicine

Influence of Immobilization, Stretching, and Activity on the Morphological Properties of Spastic Gastrocnemius Muscles.

Habersack A, Kruse A, Guggenberger B et al. · 2026 · Children (Basel, Switzerland)

Background/Objectives: Children with cerebral palsy (CP) often develop altered muscle architecture and calf muscle contractures. Orthotic immobilization aims to provide prolonged stretch to lengthen the muscle belly and muscle-tendon unit…

View details →DOI: 10.3390/children13030414
Negative / Null Result ReportMedicine

Effects of Time of Arrival on Trauma Patient Outcomes.

LaRosa SK, Stone XA, Fenninger AA et al. · 2024 · The American surgeon

Background Arriving during "off hours" to the hospital can put patients at greater risk of complications or mortality given lesser staff. Our goal was to investigate this in trauma patients with an Injury Severity Score (ISS) of >15. We…

View details →DOI: 10.1177/00031348241248694
Negative / Null Result ReportMedicine

Motor and Cognitive Sequence Tasks Exhibit Different Ramping Patterns in Parietal and Prefrontal Cortices.

Doyle H, Yewbrey R, Kornysheva K et al. · 2025 · Journal of cognitive neuroscience

Humans complete different types of sequences as a part of everyday life. These sequences can be divided into two important categories: those that are abstract, in which the steps unfold according to a rule at super-second to minute time…

View details →DOI: 10.1162/jocn_a_02349
Negative / Null Result ReportMedicine

Climatic resilience: Marine heatwaves do not influence the variations of green crab (Carcinus maenas) megalopae supply patterns to a Western Iberian estuary.

Monteiro M, Azeiteiro UM, Queiroga H · 2024 · Marine environmental research

Extreme climatic events like marine heatwaves (MHWs) are becoming more frequent, intense, and longer lasting all around the world. The consequences of these anomalously warm periods are devastating for marine ecosystems. Still, little is…

View details →DOI: 10.1016/j.marenvres.2024.106567
Negative / Null Result ReportOpen accessMedicine

Flexible Goal Adjustment Predicts Well-Being Before and After Retirement.

Viegas LM, Bermeitinger C, Greve W · 2026 · Journal of aging research

Background and objectives Retirement represents a critical life change and is accompanied by the blocking of professional goals. We assume that the individual capability to adapt goals to changed conditions has a palliative effect on…

View details →DOI: 10.1155/jare/2950011
Negative / Null Result ReportMedicine

An acute social stressor decreases reinforcing value of both high and low energy-dense food in college students in a randomized controlled trial.

McKay NJ, Horvatits EJ, Jean M et al. · 2024 · Physiology & behavior

It is well known that a large portion of the population elevates their intake of high energy-dense foods during times of stress; however, it is understudied whether stress affects the reinforcing value of a food reward. Further knowledge…

View details →DOI: 10.1016/j.physbeh.2024.114531
Negative / Null Result ReportOpen accessMedicine

Oxytocin administration during labor does not affect maternal serum oxytocin levels, early postpartum breastfeeding attitude and maternal attachment.

Özdemir M, Çeber Turfan E, Keskin HL · 2025 · PloS one

The goal was to investigate the effects of synthetic oxytocin administration during labor on maternal and neonatal serum oxytocin levels, early breastfeeding attitudes, and postpartum maternal attachment immediately after birth. This…

View details →DOI: 10.1371/journal.pone.0337762
Negative / Null Result ReportOpen accessMedicine

Contribution of sympathetic nervous system activation to endothelial ischemia reperfusion injury in healthy adults.

Rosenberg AJ, Young BE, Fernandez A et al. · 2025 · Physiological reports

Ischemia-reperfusion injury (IRI) describes the phenomenon through which the restoration of blood flow following prolonged ischemia exacerbates tissue damage during reperfusion. IRI can be modeled by inducing 20-min arm ischemia followed…

View details →DOI: 10.14814/phy2.70502