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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 638 of 725

Negative / Null Result ReportMedicine

Changes in Distress Screening and Information Reception Among Cancer Patients Following a Training for Oncology Nursing Staff: A Pilot Study.

Dreismann, Zimmermann · 2026 · Cancer medicine

At least half of all cancer patients suffer from significant psychological distress, yet despite well-validated screening procedures, distress often goes unrecognized or untreated. For this reason, a special training (OptiScreen-Training)…

View details →DOI: 10.1002/cam4.71994
Negative / Null Result ReportMedicine

Does the killer turn angle in biceps tenodesis lead to a guillotine effect? A biomechanical study.

Kaymakoglu, Duymaz, Karabag et al. · 2026 · Journal of orthopaedic surgery and research

The purpose of this study was to investigate whether a killer turn angle in biceps tenodesis creates a guillotine-like effect under physiological loading conditions and to evaluate its influence on tendon elongation and tunnel widening. 30…

View details →DOI: 10.1186/s13018-026-07007-8
Negative / Null Result ReportMedicine

Association of lumbar vertebral hemangiomas with low back pain, morphological changes, and quality of life: a cross-sectional study.

Yang, Becker, Mödl et al. · 2026 · BMC musculoskeletal disorders

Vertebral hemangiomas are common benign spinal lesions. But studies of lumbar vertebral hemangiomas (LVHs) are still relatively limited. In this work, we assessed the distribution of LVHs within the study population, and explored their…

View details →DOI: 10.1186/s12891-026-10021-w
Negative / Null Result ReportMedicine

Effect of okara and biovalorised okara consumption on postprandial amino acid response: a crossover randomised controlled trial.

Lee, Mak, Leong et al. · 2026 · European journal of clinical nutrition

Okara is a protein-rich food by-product that can be biovalorised with Rhizopus oligosporus to improve its protein digestibility and quality. This study investigated postprandial circulating amino acid changes following okara and…

View details →DOI: 10.1038/s41430-026-01769-4
Negative / Null Result ReportMedicine

Endoscopic versus open flexor hallucis longus tendon transfer for reconstruction of chronic achilles tendon rupture: A prospective randomized pilot trial.

Afifi, Hewaidy, El Shazly et al. · 2026 · Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons

Chronic Achilles tendon rupture often requires surgical reconstruction. Flexor hallucis longus (FHL) tendon transfer is widely used, and endoscopic techniques may reduce soft-tissue morbidity and facilitate early recovery. Thirty patients…

View details →DOI: 10.1016/j.fas.2026.05.015
Negative / Null Result ReportMedicine

Perception of the malar midface of patients with class III malocclusion after Le Fort I osteotomy.

Brochet, Cresseaux, Varazzani et al. · 2026 · Journal of stomatology, oral and maxillofacial surgery

Maxillo-zygomatic hypoplasia is common in patients with a Class III malocclusion, resulting in a flat and concave appearance of the midface. Le Fort I osteotomy is considered to be an effective treatment for occlusal and facial aesthetic…

View details →DOI: 10.1016/j.jormas.2026.102866
Negative / Null Result ReportMedicine

The environmental cost of learning: CO 2 emission comparisons of virtual reality, online, and alternative distance education.

Istrate, Van Gelder, Szőllősi et al. · 2026 · Intensive care medicine

Environmental sustainability has become a critical concern across various sectors, including education and healthcare. Professional training programmes, particularly in intensive care medicine, are essential for maintaining competency but…

View details →DOI: 10.1007/s00134-026-08460-z
Negative / Null Result ReportMedicine

Lumbar Function and Muscle Preservation Following Hybrid Surgery Versus Selective Thoracic Fusion in Adolescent Idiopathic Scoliosis: A Preliminary Comparative Study.

Tasdemir, Korkmaz, Durak et al. · 2026 · Turkish neurosurgery

To investigate lumbar motion and muscle change following hybrid surgery in adolescent idiopathic scoliosis (AIS). We conducted a prospective study design including 16 patients (14 female, 2 male) who underwent either hybrid surgery or…

View details →DOI: 10.5137/1019-5149.jtn.49086-25.3
Failed Experiment ReportMedicine

Evaluation of Neonatal Sprague-Dawley Rats as a Potential Animal Model for the Neurovirulence Test of an Iranian Mumps Vaccine Strain, RS-12.

Mohammad Kazem, Mohammad, Mohammad Hasan et al. · 2025 · Archives of Razi Institute

Mumps virus (MuV), a neurotropic member of paramyxoviridae, causes mumps disease. Since the 1960s, when the first live-attenuated vaccine against the MuV was developed, mumps outbreaks have dramatically decreased. A monkey-based…

View details →DOI: 10.32598/ari.80.5.3696
Negative / Null Result ReportMedicine

Randomized Phase II Study of Bortezomib, Lenalidomide, and Dexamethasone (VRD) Versus Lenalidomide and Dexamethasone (RD) in Elderly Patients with Newly Diagnosed Multiple Myeloma (KMM1910).

Yi, Yoon, Lee et al. · 2026 · Cancer research and treatment

While triplet regimens are considered optimal for treatment of multiple myeloma (MM), the benefit of adding bortezomib to lenalidomide and dexamethasone remains prospective-wise unclear in elderly patients due to frailty and potential…

View details →DOI: 10.4143/crt.2026.0255
Negative / Null Result ReportMedicine

Robotic segmental ureterectomy for upper tract urothelial carcinoma: comparable short-term oncological outcomes and improved postoperative recovery compared to open approach.

Lasmanovich, Chepeliuk, Fihman et al. · 2026 · World journal of surgical oncology

Segmental ureterectomy (SU) is an established kidney-sparing strategy for upper tract urothelial carcinoma (UTUC), yet few studies have compared the standard open approach to the emerging robotic modality. We performed a clinical outcome…

View details →DOI: 10.1186/s12957-026-04422-3
Negative / Null Result ReportMedicine

Impact of the MonCœur smartphone application on self-care and quality of life in heart failure: The APPLIMONCOEUR randomized trial.

Berthelot, Audureau, Bouleti et al. · 2026 · Archives of cardiovascular diseases

The MonCœur smartphone application (app) was developed to meet the specific needs of individuals living with heart failure (HF). To evaluate whether the MonCœur smartphone app improves self-care at 6months in patients with HF,…

View details →DOI: 10.1016/j.acvd.2026.04.007
Negative / Null Result ReportMedicine

Ring-augmented versus conventional one-anastomosis gastric bypass: Perioperative and short-term results in the randomized controlled RiMini trial.

Tissink, Timmerman, Vermeer et al. · 2026 · PloS one

Recurrent weight gain remains a challenge in metabolic bariatric surgery (MBS). Recent publications focused on ring-augmented Roux-en-Y gastric bypass (RYGB) and ring-augmented sleeve gastrectomy (SG), but few studies have addressed the…

View details →DOI: 10.1371/journal.pone.0349793
Negative / Null Result ReportMedicine

Impact of virtual reality versus conventional balance training on balance function and fear of falling in older adults: a single blinded, randomized controlled trial.

Shamsoddini, Cheraghifard · 2026 · European geriatric medicine

Balance issues and the fear of falling are among the primary factors contributing to falls in older people, leading to injury and a decline in quality of life. A single-blind, randomized, controlled trial was conducted involving 34 older…

View details →DOI: 10.1007/s41999-026-01493-z
Negative / Null Result ReportMedicine

Outcome of segmentectomy vs. lobectomy in patients with cT1a-b N0 lung cancer and postoperative N1 upstaging.

Kaman, Stork, Okumus et al. · 2026 · Langenbeck's archives of surgery

Segmentectomy is offered in selected patients with clinical T1a-b N0 M0 lung cancer. In case of positive N1 lymph node at fresh frozen section, conversion to lobectomy is recommended. Indication for redo surgery and completion lobectomy in…

View details →DOI: 10.1007/s00423-026-04089-0
Failed Experiment ReportMedicine

Antiviral Prophylaxis for Delayed Facial Nerve Palsy Following Vestibular Schwannoma Resection: Single Institutional Series With Systematic Literature Review and Meta-Analyses of 7136 Patients.

Blue, Alvarez, Hines et al. · 2026 · Neurosurgery

Delayed facial nerve palsy (DFNP) is a recognized complication of vestibular schwannoma resection, with proposed mechanisms including viral reactivation, inflammation, and ischemia. Elevated herpes simplex virus and varicella zoster virus…

View details →DOI: 10.1227/neu.0000000000004096
Negative / Null Result ReportMedicine

Dobutamine versus milrinone for inferior ST-segment elevation myocardial infarction with right ventricular involvement: a retrospective cohort study.

Wang, Xiao, Li et al. · 2026 · Frontiers in pharmacology

Inferior ST-segment elevation myocardial infarction (STEMI) complicated by right ventricular involvement (RVMI) leads to right-heart-dominant failure and a higher incidence of cardiogenic shock (CS). Evidence guiding the choice between…

View details →DOI: 10.3389/fphar.2026.1785400
Negative / Null Result ReportMedicine

[Evaluation of the Efficacy and Tolerance of Tranexamic Acid Combined with Inoserp TM PAN-AFRICA Antivenom in the Treatment of Hemorrhagic Syndrome during Envenomation by Echis ocellatus in Benin].

Larréché, Sodjinou, Tourita et al. · 2026 · Medecine tropicale et sante internationale

Hemorrhagic syndrome accounts for a significant proportion of the mortality and morbidity associated with snakebites in sub-Saharan Africa. Hyperfibrinolysis, which has been reported in some cases, suggests the potential benefit of…

View details →DOI: 10.48327/mtsi.v6i1.2026.745
Negative / Null Result ReportMedicine

Variation of Normal Thymic Veins With Age And Gender in a Large Series of Subjects on Enhanced Multidetector Computed Tomography.

Yang, Dong, Song et al. · 2026 · Current medical imaging

The thymic veins are small vessels located in the anterior superior mediastinum, and thymic tissue undergoes physiological degeneration with age. Multidetector computed tomography (MDCT) with isotropic resolution allows comprehensive…

View details →DOI: 10.2174/0115734056473336260407214814
Failed Experiment ReportMedicine

Transcranial Direct Current Stimulation Combined with Neurofunctional Motor Training in Autistic Children: A Randomized, Sham-Controlled, Double-Blind Clinical Trial.

Araujo, Araujo, Silva et al. · 2026 · Journal of motor behavior

The study investigated the effects of ten 20-minute sessions of neurofunctional motor training combined with anodal transcranial direct current stimulation (tDCS) over the primary motor cortex or cerebellum on motor skills in autistic…

View details →DOI: 10.1080/00222895.2026.2668719
Negative / Null Result ReportMedicine

The Effect of Canagliflozin Dose on Renal and Cardiovascular Outcomes in Type 2 Diabetes and High Cardiovascular Risk.

Elenjickal, Baroz, Boileau et al. · 2026 · Diabetes, obesity & metabolism

Pharmacokinetic data suggest a potential dose-dependent effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on surrogate markers of efficacy, but the impact of SGLT-2 inhibitor dose on renal and cardiovascular outcomes remains…

View details →DOI: 10.1111/dom.70886