e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21363 results · page 626 of 713

Negative / Null Result Report

Adaptive deletion of functional duplicate genes in Drosophila

dos Santos ALC, Assis R · 2025 · Preprint

ABSTRACT Gene deletion is traditionally viewed as a nonadaptive mechanism that eliminates functional redundancy, yet emerging evidence indicates that it disproportionately affects tissue-specific duplicates with unique functions. Here, we…

View details →DOI: 10.64898/2025.12.19.695606
Negative / Null Result ReportMedicine

Assessing Perpetrator Responses to Confrontation: Associations with a DARVO-SF and Posttrauma Symptoms in Two Different Populations.

Durland M, Harsey SJ, Freyd JJ · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

DARVO (Deny, Attack, Reverse Victim and Offender) is a common tactic used by perpetrators of interpersonal violence to deflect blame and responsibility. Individuals' exposure to perpetrator DARVO has previously been measured using the…

View details →DOI: 10.1080/15299732.2025.2599757
Negative / Null Result Report

Beyond the Size Tag: Clothing Influences on Body Image and Mood

Abrevaya S, Rossi C, Rodgers R · 2025 · Preprint

Clothing size labels have been shown to influence women's mood, self-esteem, and body satisfaction. This study examined the effects of different sizing nomenclatures—specifically color-based versus category-based labeling—on women's body…

View details →DOI: 10.31234/osf.io/ruawg_v1
Negative / Null Result ReportMedicine

Parental knowledge, attitudes, and behaviors toward childhood headache: the impact of parental migraine.

Bayır BRH, Ulutaş C, Nazlı E et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Introduction Headache is one of the most common neurological complaints in children and adolescents. Headache especially migraine in childhood significantly impacts daily life activities, including academic performance, and social…

View details →DOI: 10.1007/s10072-026-09145-7
Negative / Null Result ReportMedicine

Exogenous dsRNA made accessible to Dicer by two eukaryotic RNA-dependent RNA polymerases in Paramecium tetraurelia.

Pirritano M, Buescher J, Staubach P et al. · 2026 · Communications biology

Discrimination of self from non-self RNA is a critical requirement for any cell to respond to infections and to maintain cellular integrity. We report novel functions for two RNA-dependent RNA polymerases (RDRs) in Paramecium. In…

View details →DOI: 10.1038/s42003-025-09443-4
Negative / Null Result ReportMedicine

The role of anxiety and self-compassion in the link between trauma and alcohol use among American Indians.

Spicher J, Wood ZJ, John-Henderson NA · 2026 · Journal of health psychology

Historical trauma and ongoing systemic inequities contribute to elevated levels of anxiety and problematic alcohol use among American Indians. The current study examines the relationship between recent trauma and problematic alcohol use,…

View details →DOI: 10.1177/13591053251390400
Negative / Null Result Report

Children’s Social Media Use, Depression, and Socioeconomic Inequalities - A Longitudinal Investigation Based on the ABCD Study®

Ackermans M, Sauce B, Miedzobrodzka E · 2025 · Preprint

This study investigated the moderating roles of socioeconomic status (SES) and social media use (SMU) in predicting changes in children’s depressive symptoms over 2 years. Data from 8182 American children (aged 10-14, 52.8% males, 53.6%…

View details →DOI: 10.31234/osf.io/ew5kv_v1
Negative / Null Result ReportMedicine

Driving habits and difficulties in people with epilepsy: A survey.

Guillermier L, Sabourdy C, Four E et al. · 2026 · Epilepsy & behavior : E&B

Epilepsy is a neurological condition that can interfere with driving abilities through seizures and cognitive impairments. While legal frameworks often regulate driving eligibility, little is known about how people with epilepsy perceive…

View details →DOI: 10.1016/j.yebeh.2025.110824
Negative / Null Result ReportMedicine

Exploring factors influencing the ecological host range of Trissolcus japonicus: foraging strategy and nontarget host use.

Paul RL, Porter DC, Mutschler-Aldine S et al. · 2026 · Environmental entomology

Evaluation of potential classical biological control agents typically begins with laboratory testing for their fundamental host range. These experiments are intended to evaluate the propensity for nontarget attack but often do so in highly…

View details →DOI: 10.1093/ee/nvaf125
Negative / Null Result ReportMedicine

DNA-PAINT resolves E-cadherin-independent cross-junctional F-actin organization in Drosophila embryonic tissue.

Häring M, Zhang Y, Zhang N et al. · 2026 · Biophysical journal

Cell junction remodeling is central to epithelial morphogenesis and tissue rheology and depends on the interplay between adhesion molecules and the actomyosin cortex. E-cadherin constitutes the molecular basis for epithelial cell adhesion,…

View details →DOI: 10.1016/j.bpj.2026.01.026