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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 620 of 725

Negative / Null Result ReportOpen accessMedicine

Arbuscular mycorrhizal symbiosis enhances the cadmium stress tolerance of Medicago sativa in association with regulation of the aminolevulinic acid pathway.

Li Y, Wang Z, Xu T et al. · 2026 · BMC plant biology

Arbuscular mycorrhizal (AM) fungi can effectively enhance the photosynthesis and antioxidant capacity of plants under cadmium stress; however, the underlying regulatory mechanisms remain poorly understood. This study focuses on the…

View details →DOI: 10.1186/s12870-026-08798-y
Negative / Null Result ReportOpen accessMedicine

Methane mitigation, nutritional evaluation, and in vitro degradation kinetics of diets based on tropical grass haylage treated with xylanase.

Duarte ABA, Dias-Silva TP, Viana WCC et al. · 2026 · Tropical animal health and production

The aim of this study was to evaluate the effect of xylanase addition (1.8 g/kg dry matter [DM]) to tropical grass haylage used in total mixed rations (TMR) on in vitro organic matter degradability, ruminal fermentation kinetics, and…

View details →DOI: 10.1007/s11250-026-05183-7
Negative / Null Result ReportMedicine

Engineering a synthetic niche for hADSC preconditioning with PRP, Lp-SN, and resveratrol nanoparticles.

Abbasi S, Akbari N, Yazdani M et al. · 2026 · Artificial cells, nanomedicine, and biotechnology

Ex vivo expansion of human adipose-derived stem cells (hADSCs) remains challenging because reduced-serum culture conditions can compromise short-term cell function. Here, we evaluated a microenvironment-inspired tri-component…

View details →DOI: 10.1080/21691401.2026.2691659
Negative / Null Result ReportMedicine

Temporal and suprathreshold central auditory skills in individuals with migraine: a comparative study based on clinical features.

Özkar B, Söylemez E · 2026 · Neurological research

Objective Previous studies evaluating central auditory processing in migraine have used conventional tests, but the findings have remained inconsistent. This study aimed to assess the central auditory abilities of individuals with migraine…

View details →DOI: 10.1080/01616412.2026.2620484
Failed Experiment ReportMedicine

Dissolved inorganic carbon driven dynamics of calcite shell formation in 12 strains of the freshwater algae Phacotus lenticularis (Chlorophyta).

Gruenert U, Benda J, Bossdorf O et al. · 2026 · PloS one

The present rise in temperature, pCO2 and altered precipitation impact lake water alkalinity and dissolved inorganic carbon (DIC) dynamics. Such changes on carbonate chemistry have been shown to modify calcification of shell-forming…

View details →DOI: 10.1371/journal.pone.0349771
Negative / Null Result ReportOpen accessMedicine

Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.

Tayebi SM, Mirzaei M, Stout JR · 2026 · Journal of the International Society of Sports Nutrition

Purpose High-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery. This randomized, double-blind, placebo-controlled pilot trial examined whether acute β -hydroxy- β -methylbutyrate free acid (HMB-FA)…

View details →DOI: 10.1080/15502783.2026.2665962
Negative / Null Result ReportOpen accessMedicine

CO<sub>2</sub>-Extract-Based Phytopreparation from <i>Arctium tomentosum</i> Mill. Root Exhibits No Acute and Subacute Toxicity and Suppresses Xylene-Induced Ear Edema and LPS-Induced Acute Inflammation in Mice.

Aitynova A, Dyusebaeva M, Issayeva D et al. · 2026 · Molecules (Basel, Switzerland)

A phytopreparation based on the CO 2 extract of Arctium tomentosum Mill. root (AT) was evaluated for its safety and anti-inflammatory potential in Swiss albino mice. Acute and 28-day subacute oral toxicity studies demonstrated that AT, at…

View details →DOI: 10.3390/molecules31111900
Negative / Null Result ReportMedicine

Parameter Specific Modulation of Neuronal Firing and Extracellular Action Potential Dynamics by Transcranial Focused Ultrasound Stimulation in Rat Motor Cortex.

Huang H, Smets C, Chen L et al. · 2026 · Brain stimulation

Background Transcranial focused ultrasound stimulation (TUS) has emerged as a promising tool for noninvasive neuromodulation. However, the specific effects of stimulation parameters on neural activity remain incompletely understood.…

View details →DOI: 10.1016/j.brs.2026.103145
Negative / Null Result ReportMedicine

Exploring the Association of Religion and Religiosity on Mammography Screening Among White and Black Women: Results from the Brazilian Longitudinal Study of Aging (Elsi-Brazil).

Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health

This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…

View details →DOI: 10.1007/s10943-026-02694-3
Negative / Null Result ReportMedicine

Effect of a 3.5 mm Tibial Plateau Leveling Osteotomy Locking Compression Plate on Serial Postoperative Tibial Plateau Angle Maintenance, Short-Term Osteotomy Healing, and Complication Rates in 45 to 70 kg Dogs.

Acuña J, Barnhart MD, Kennedy SC et al. · 2026 · Veterinary and comparative orthopaedics and traumatology : V.C.O.T

To evaluate the effect of a 3.5 mm tibial plateau leveling osteotomy (TPLO) locking compression plate on serial postoperative tibial plateau angle (TPA) maintenance, short-term osteotomy healing, and complication rates in dogs weighing 45…

View details →DOI: 10.1055/a-2865-3650
Negative / Null Result ReportOpen accessMedicine

Cardiac response to chronic restraint stress involves mineralocorticoid receptors in male Sprague-Dawley rats.

Sztechman D, Zera T, Czarzasta K et al. · 2025 · Physiological reports

In the present study, we aimed at elucidating whether exposure to chronic stress affects the expression of cardiac mineralocorticoid receptors (MRs), whether it influences cardiac structure and function, and whether MRs blockade attenuates…

View details →DOI: 10.14814/phy2.70549
Negative / Null Result Report

Innovation and Productivity as Engines of Economic Growth in Ghana

Xuhua H, Bakpa EK, Yeboah JA · 2026 · Preprint

This paper examines the dynamic relationship between innovation, total factor productivity (TFP), and economic growth in Ghana using annual data for the period 1965–2021. Although Ghana has recorded relatively strong economic growth,…

View details →DOI: 10.20944/preprints202604.1738.v1
Negative / Null Result ReportMedicine

Investigation of Metabolites and Mineral Content in Blood Serum of Dairy Cows of the Simmental Breed in Samsun Province During the Transition Period.

Ormancı N, Bölükbaş B, Waqas M et al. · 2026 · Biological trace element research

This study evaluated the metabolic and mineral profiles in the blood serum of Simmental dairy cows during the transition period to assess their energy, protein, and mineral status. A total of 78 cows from 10 farms in Samsun Province were…

View details →DOI: 10.1007/s12011-026-04984-z
Negative / Null Result ReportOpen accessMedicine

Effect of Orthodontic Tube Base Area and Enamel Sandblasting on Bonding Strength to Enamel: An In Vitro Study.

Osipovė K, Maldonytė L, Lukšys D et al. · 2026 · Journal of clinical medicine

Background : The bond strength of orthodontic tubes to the enamel surface is essential for maintaining appliance stability, especially due to high masticatory forces on molars. Strong adhesion reduces the need for rebonding, shortening…

View details →DOI: 10.3390/jcm15020579
Negative / Null Result ReportMedicine

How does organizational sacralization affect healthcare professionals' work engagement and turnover intentions through perceived organizational support?

Şengüllendi MF · 2026 · Journal of health organization and management

Purpose In recent years, the migration of healthcare professionals from developing countries to developed countries has accelerated. Türkiye is one of the countries negatively affected by the migration of healthcare professionals. This…

View details →DOI: 10.1108/jhom-08-2024-0352
Negative / Null Result ReportMedicine

Studying with Friends in Introductory Biology Is Associated with Low Impact Study Strategies and No Improvement of Exam Scores.

Williams AE, Denaro K · 2026 · CBE life sciences education

Students often choose to study for exams with friends. Since active learning in class boosts success, instructors might expect studying with peers to also help. However, research offers little support for this. We investigated whether…

View details →DOI: 10.1187/cbe.25-04-0074
Negative / Null Result ReportMedicine

The effect of artificial intelligence-assisted applications on the perception of nursing values and the mediating role of resilience.

Cura ŞÜ, Atay S, Çimen Işık M et al. · 2026 · BMC nursing

Background Artificial İntelligence (AI)-assisted applications are becoming widespread in nursing practice and are creating a significant transformation in care processes. While this transformation may influence nurses' perceptions of…

View details →DOI: 10.1186/s12912-026-04763-0