Negative / Null Result ReportOpen accessMedicine
Nasirzadeh A, Mohammadzadeh F, Kazeminia S et al. · 2025 · Scientific reports
The presence of a known labor companion was shown to improve childbirth satisfaction. However, a companion's anxiety might affect the satisfaction of laboring women. Therefore, this study aimed to evaluate the relationship between the…
View details →DOI: 10.1038/s41598-025-04754-2 Negative / Null Result Report
Alroba R, Alfakhri A, Badreldin HA et al. · 2024 · Preprint
Purpose: This study aims to investigate the potential causal relationship between the use of indapamide and rhabdomyolysis. Previous research and pharmacovigilance monitoring activities have suggested a potential association between…
View details →DOI: 10.22541/au.171825395.50079448/v1 Negative / Null Result ReportOpen accessMedicine
Veenman F, Tibbertsma S, Wolvius EB et al. · 2025 · Caries research
Introduction Asthma and dental caries may be linked through frequent mouth breathing and the use of inhaled asthma medication. However, the current literature is inconclusive on whether asthma or asthma medications increase the risk of…
View details →DOI: 10.1159/000547594 Negative / Null Result Report
Watanabe RAS, Nishiyama F, Lyra L et al. · 2024 · Preprint
Background and Objectives Respiratory syncytial virus (RSV) is responsible for most cases of acute viral bronchiolitis (AVB) in childhood. The association of factors such as RSV subtype, viral load, and viral coinfection with severe…
View details →DOI: 10.1101/2024.08.29.24312713 Negative / Null Result ReportOpen accessMedicine
Whelton SP, Yao J, Clish C et al. · 2026 · Journal of the American Heart Association
Background Aortic valve calcification (AVC) is the primary process leading to aortic stenosis. We examined whether polygenic risk scores (PRS) are associated with AVC beyond traditional atherosclerotic cardiovascular disease risk factors.…
View details →DOI: 10.1161/jaha.124.040064 Negative / Null Result ReportOpen accessMedicine
Isaacs Q, Sofianos C, Muganza A et al. · 2026 · European burn journal
Background: Timely admission to a specialised burn unit is considered crucial for optimising outcomes in burn patients. However, the impact of delayed admission on hospital length of stay and clinical outcomes remains unclear, particularly…
View details →DOI: 10.3390/ebj7020032 Negative / Null Result ReportOpen accessMedicine
Zhao J, Li W, Chen L et al. · 2024 · Frontiers in endocrinology
Objective Despite several observational studies attempting to investigate the potential association between type 1 diabetes mellitus (T1DM) and the risk of digestive cancers, the results remain controversial. The purpose of this study is…
View details →DOI: 10.3389/fendo.2024.1407329 Negative / Null Result ReportOpen accessMedicine
Pietraszko P, Żórawski M, Bielecka-Richter E et al. · 2025 · International journal of molecular sciences
Mid-regional pro-adrenomedullin (MR-proADM) has emerged as a promising biomarker reflecting endothelial dysfunction and systemic inflammation. Its prognostic role in cardiovascular complications, particularly in the context of COVID-19…
View details →DOI: 10.3390/ijms262010081 Negative / Null Result ReportMedicine
Weber J, Heming M, Apolinário-Hagen J et al. · 2024 · Biological psychology
Valid approaches to conveniently measure stress reactivity are needed due to the growing evidence of its health-impairing effects. This study examined whether the Perceived Stress Reactivity Scale (PSRS) predicts cardiovascular and…
View details →DOI: 10.1016/j.biopsycho.2024.108762 Negative / Null Result ReportMedicine
Kaabi YA, Abdelmola AA, Abdelwahab SI et al. · 2024 · Clinical laboratory
Background Type 2 diabetes mellitus (T2DM) is common in Saudi Arabia and represents a major health concern. Silent information regulator of transcription-1 (SIRT1) positively influences insulin sensitivity and might contribute to the…
View details →DOI: 10.7754/clin.lab.2023.230804 Negative / Null Result ReportMedicine
Chiarelli PA, Chapman N, Flyer BE et al. · 2024 · Journal of neurosurgery. Pediatrics
Objective The optimal timing of ventricular shunt placement in low-weight and preterm infants remains an unresolved topic in modern pediatric neurosurgery. Shunt placement for hydrocephalus is performed over a wide range of infant weights,…
View details →DOI: 10.3171/2024.1.peds23333 Negative / Null Result Report
Quyen AT, Nakamura S, Watanabe K et al. · 2023 · Preprint
Abstract Although the correlation between loneliness and both the development and management of diabetes has been gradually uncovered, the finding was inclusive. Furthermore, this aspect has yet to be researched in the Japanese populace.…
View details →DOI: 10.21203/rs.3.rs-3435930/v1 Negative / Null Result ReportMedicine
Boucher V, Frenette J, Neveu X et al. · 2023 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Approximately 15 % of individuals who sustained a mild Traumatic Brain Injury (TBI) develop persistent post-concussion symptoms (PPCS). We hypothesized that blood biomarkers drawn in the Emergency Department (ED) could help predict PPCS.…
View details →DOI: 10.1016/j.jocn.2023.10.007 Negative / Null Result ReportMedicine
Sawa K, Ihara Y, Imai T et al. · 2024 · Clinical lung cancer
Background The number of patients undergoing hemodialysis continues to increase globally, and the incidence of cancer is high among these patients. Immune checkpoint inhibitors are widely used in patients with advanced cancer, especially…
View details →DOI: 10.1016/j.cllc.2023.11.003 Negative / Null Result ReportOpen accessMedicine
Seizer L, Löchner J, Renner TJ · 2026 · Brain, behavior, & immunity - health
The interaction between the immune system and the central nervous system has been implicated in the development of psychiatric disorders in adult patients. However, comprehensive data regarding pediatric psychiatry are still lacking. This…
View details →DOI: 10.1016/j.bbih.2025.101143 Negative / Null Result ReportOpen accessMedicine
Howard KA, Witrick B, Clark A et al. · 2026 · The Journal of surgical research
Introduction Implicit bias can influence behavior and decision-making, such as treatment decisions in clinical settings. Given documented Black-White disparities in vascular care, the purpose of this study was to describe the prevalence…
View details →DOI: 10.1016/j.jss.2026.02.004 Negative / Null Result ReportOpen accessMedicine
Pires S, Freitas M, Pinho F et al. · 2025 · Sensors (Basel, Switzerland)
Objective We aimed to quantify the mechanical pressure required to reach the deep cervical and thoracolumbar fasciae, to examine its association with pressure pain threshold (PPT) and adipose tissue thickness, and to determine whether PPT…
View details →DOI: 10.3390/s25165073 Negative / Null Result ReportOpen accessMedicine
Haahr Vad O, Önnestam L, Bengtsson Boström K et al. · 2025 · PloS one
Aims The aim of the study was to investigate the association between breastfeeding duration and body mass index (BMI), overweight and obesity in children during follow-up until 16 years of age. Methods Observational cohort study of mothers…
View details →DOI: 10.1371/journal.pone.0319502 Negative / Null Result ReportOpen accessMedicine
Montoya-Delgado IB, Ochoa-García IV, Escobedo-Salcedo ZL et al. · 2026 · International journal of molecular sciences
Severe asthma (SA) is a chronic respiratory disease characterized by clinical heterogeneity and poor therapeutic response. Variants in the IL4 gene, including rs2243250 and rs2243248, have been associated with asthma susceptibility and…
View details →DOI: 10.3390/ijms27114711 Negative / Null Result ReportOpen accessMedicine
Sacre H, Haddad C, Rizk R et al. · 2025 · Frontiers in public health
Objectives To investigate the association between food insecurity (FI), eating disorders (EDs), and orthorexia nervosa (ON) among Lebanese university students. Methods This cross-sectional study, conducted between 2021 and 2022, enrolled…
View details →DOI: 10.3389/fpubh.2025.1572654 Negative / Null Result ReportOpen accessMedicine
Wistrand H, Kaartinen NE, Jousilahti P et al. · 2024 · Integrated blood pressure control
Purpose The complex pathogenesis of hypertension, potentially involving inflammatory pathways, remains elusive. This study aimed to evaluate the relationship between 24-hour urinary sodium excretion and inflammatory cytokines alongside…
View details →DOI: 10.2147/ibpc.s483495 Negative / Null Result ReportOpen accessMedicine
Schultze A, Ju S, Drysdale M et al. · 2025 · Pharmacology research & perspectives
We report findings from three SCCS conducted to quantify the association between fluoroquinolone (FQ) use for the treatment of uncomplicated urinary tract infection (uUTI) and tendon rupture, retinal detachment, and uveitis. Female…
View details →DOI: 10.1002/prp2.70124 Negative / Null Result ReportOpen accessMedicine
Kayode GA, Zagkos L, Oboli G et al. · 2025 · PloS one
Background Subarachnoid haemorrhage (SAH) poses a life-threatening risk, contributing to half of all haemorrhagic strokes, with aneurysmal SAH (aSAH) affecting approximately 6 individuals per 100,000 annually. Following aSAH, the influx of…
View details →DOI: 10.1371/journal.pone.0329287 Negative / Null Result ReportMedicine
Rodrigues CAS, Albano TR, Pereira Melo AK et al. · 2024 · Journal of bodywork and movement therapies
Background Y-Balance Test (YBT) assesses postural stability. When is applied to patients after anterior cruciate ligament reconstruction (ACLR), it is not clear which variables influence its result. Objective To connect YBT and postural…
View details →DOI: 10.1016/j.jbmt.2024.10.016 Negative / Null Result ReportOpen accessMedicine
Harik L, Gregg AC, Wu Y et al. · 2026 · Journal of the American Heart Association
Background Patient-surgeon sex concordance influences postoperative outcomes in general surgery, but its relevance in cardiac surgery is unknown. Methods This was a cohort study of 223 065 Medicare beneficiaries undergoing coronary artery…
View details →DOI: 10.1161/jaha.125.048015 Negative / Null Result ReportOpen accessMedicine
Lee SE, Kim CW, Bae JE et al. · 2025 · Epidemiology and health
Objectives This study investigated the associations between usual source of care (USC) characteristics, which incorporate primary care functions, and medication adherence and healthy behaviors in Korean adults with diabetes. Methods We…
View details →DOI: 10.4178/epih.e2025063 Negative / Null Result ReportOpen accessMedicine
Jiang W, Cheng A, Wang J et al. · 2025 · Frontiers in neurology
Background Febrile seizures (FSs) are a common neurological manifestation in children, affecting 2%-5% of children worldwide. While acute-phase recurrences during the same febrile illness are frequent, their risk factors and implications…
View details →DOI: 10.3389/fneur.2025.1733941 Negative / Null Result ReportOpen accessMedicine
Wakayama T, Saita Y, Uchino S et al. · 2025 · Journal of clinical medicine
Objective: Platelet-rich plasma (PRP) therapy has become a popular treatment for knee osteoarthritis. We aimed to determine the outcomes of knee osteoarthritis patients following PRP therapy using magnetic resonance imaging (MRI) findings…
View details →DOI: 10.3390/jcm14186408 Negative / Null Result ReportOpen accessMedicine
Nagao-Sato S, Kushida O, Kurita Y et al. · 2025 · Nutrients
Background/Objectives : Low masticatory function has been proposed as a risk factor for sarcopenia. This study investigated its potential association with body composition and physical performance in community-dwelling older adults.…
View details →DOI: 10.3390/nu17060968 Negative / Null Result ReportMedicine
Wu J, Guo J, Wang A et al. · 2023 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Background The association between nonalcoholic fatty liver disease (NAFLD) and intracerebral hemorrhage (ICH) remains unclear. This study aimed to investigate whether NAFLD and its severity predict incident ICH. Methods Participants free…
View details →DOI: 10.1016/j.jocn.2023.09.027 