Negative / Null Result ReportOpen access
L. L. D. Paiva, Tatiane Kelly Barbosa de Azevedo, A. Pimenta et al. · 2023 · Revista Árvore
ABSTRACT This research aimed to evaluate the effect of thinning on the wood volumes per hectare on the tannin content in the bark of Mimosa caesalpiniifolia. The planting was subdivided into two plots, one thinned at 12 and 55 months of…
View details →DOI: 10.1590/1806-908820230000028 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Pankaj Puar, Nikhil Mistry, Kim A. Connelly et al. · 2023 · ESC Heart Failure
Abstract Aims Given recent suggestions that serum levels of insulin‐like growth factor‐binding protein 7 (IGFBP7) may identify patients who derive greater cardiorenal benefits from treatment with sodium‐glucose transport 2 inhibitors (SGLT2i), this exploratory sub‐analysis of the EMPA‐HEART CardioLink‐6 randomized controlled trial evaluated the association between serum levels of IGFBP7 and empagliflozin‐mediated left ventricular mass regression. Methods and results The EMPA‐HEART CardioLink‐6 trial used gold‐standard cardiac magnetic resonance imaging to detect change in left ventricular mass
View details →DOI: 10.1002/ehf2.14335 Negative / Null Result ReportOpen accessMedicine
Mina Niusha, Seyed Ali Rahmani, Leila Kohan et al. · 2023 · Asian Pacific Journal of Reproduction
Objective: To detect common chromosomal aneuploidy variations in embryos from couples undergoing assisted reproductive technology and preimplantation genetic screening and their possible associations with embryo quality. Methods: In this study, 359 embryos from 62 couples were screened for chromosomes 13, 21, 18, X, and Y by fluorescence insitu hybridization. For biopsy of blastomere, a laser was used to remove a significantly smaller portion of the zona pellucida. One blastomere was gently biopsied by an aspiration pipette through the hole. After biopsy, the embryo was immediately returned to
View details →DOI: 10.4103/2305-0500.365228 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Baravan Al-Kassou, Hasanin Al-Shaikh, Adem Aksoy et al. · 2023 · International Journal of Cardiology: Heart & Vasculature
Background: Vascular injury and bleeding complications remain frequent after transcatheter aortic valve replacement (TAVR). Whether the access-site of preprocedural coronary angiography (CAG) affects TAVR-related complications is not known. The aim of this study was to evaluate the impact of transradial (TRA) versus transfemoral access (TFA) for preprocedural CAG on outcomes in patients undergoing subsequent TAVR. Methods: The study cohort included 1002 patients undergoing transfemoral TAVR, of whom 39.4% (395/1002) had undergone radial and 60.6% (607/1002) femoral access for pre-TAVR CAG. The
View details →DOI: 10.1016/j.ijcha.2023.101205 Negative / Null Result ReportOpen accessBusiness
Choudhury Mousumi, Singh Ranjit · 2016 · Acta Universitatis Sapientiae: Economics and Business
Bancassurance has evolved as a strong distribution channel in India. Bancassurance means that the insurance company and the bank come together to offer insurance products from the counter of the banks to the bank’s customer. The present study attempts to analyse customers’ perception regarding assurance of bancassurance channel in providing insurance-related services. The study also tries to find out the impact of various demographic variables on customers’ perception regarding assurance of bancassurance channel. The study finds that customers consider bancassurance channel having high assuran
View details →DOI: 10.1515/auseb-2016-0005 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Shih-Wei Lai, Shih-Wei Lai, Cheng-Li Lin et al. · 2017 · Frontiers in Pharmacology
Background/Objectives: Previous studies showed that zolpidem use could be associated with increased cancer risk, but the role of zolpidem on hepatocellular carcinoma (HCC) risk remains undetermined. The study purpose was to examine the association between HCC risk and zolpidem use in Taiwan.Methods: Using the database from the Taiwan National Health Insurance Program, we designed a case-control study which consisted of 77986 subjects aged 20 years or older with newly diagnosed HCC as the case group, and 77986 subjects without HCC as the control group, from 2000 to 2011. Ever use of zolpidem wa
View details →DOI: 10.3389/fphar.2017.00767 Negative / Null Result ReportOpen accessPublic aspects of medicine
Sonia Oveisi, Roghaye Keshavarz Sadegh, Sina Hosainzade et al. · 2025 · Discover Social Science and Health
Abstract Background Parenting self-efficacy (PSE) describes the beliefs and attitudes of parents on their capabilities to perform well on parenting tasks. Considering its direct relation to the physical and mental development of the children, we evaluated PSE in Iranian parents and investigated its potential effects on children's growth as a reflection of their self-regulation. Methods This investigation was conducted in 2019 in Takestan, Iran, and aimed to assess PSE in 300 parents of children under 2 years old. Families filled out a demographic questionnaire and a PSE questionnaire containin
View details →DOI: 10.1007/s44155-025-00196-3 Negative / Null Result ReportOpen accessMedicine
Zainab Almussa · 2021 · The Medical Journal of Basrah University
Abstract: Introduction: Low birth weight is the best indicator of the impact in the health system and the best predictor of mortality and morbidity in the neonatal, post neonatal and childhood periods. Objectives: This study was planned to study the association between birth weight and selected risk factors in Basrah governorate with special reference to: Socio demographic factors, Present obstetric history, Past obstetric history, History of Ante Natal Care, and Medical history. Methods: This is hospital- based cross sectional study was conducted on 362 infants delivered and /or admitted to A
View details →DOI: 10.33762/mjbu.2021.129962.1070 Negative / Null Result ReportOpen accessPublic aspects of medicine
Sanjay B Tripathi, Vishakha K Kapadia · 2015 · National Journal of Community Medicine
Objectives: To evaluate the clinical profile and the factors influencing treatment outcome of TB patients co-infected with HIV attending DOT centers of Southeast area of Ahmedabad, Gujarat Methodology: A Prospective observation study was conducted to assess the treatment outcome of TB in TB-HIV co-infected patients on DOTs conducted at L.G. Hospital and tuberculosis units (TUs) of south and east region of Ahmedabad. TB patients started DOTS were registered and were followed till treatment outcome was declared. Results: The treatment success rate was found to be 84.17% (101 of 120 patients). Tr
Negative / Null Result ReportOpen accessMedicine
Artha Falentin Putri Susilo, Hanom Husni Syam, Hartanto Bayuaji et al. · 2024 · Scientific Reports
Abstract Vitamin D and calcium in follicular fluid play an important role in modulating steroidogenesis, folliculogenesis, and oocyte quality determination. Both collaborate to produce top-quality embryos (TQE) during in vitro fertilization (IVF). In this study, we compared free 25(OH)D3 and calcium levels in follicular fluid between TQE and non-TQE groups. This cross-sectional study included women who underwent IVF procedures at tertiary hospitals in Bandung, Indonesia. Ovarian follicular fluid was collected during the ovum pick-up procedure. The examination of 25(OH)D3 levels, vitamin d-bind
View details →DOI: 10.1038/s41598-024-71769-6 Negative / Null Result ReportOpen accessMedicine
Sarah Moreira de Sousa Gomes, Paulo César Apolinário de Souza, Cassiane Freitas Rodrigues et al. · 2026 · DST
Introduction: Women living with HIV/AIDS (WLHA) are more vulnerable to human papillomavirus (HPV) infection, particularly by high-risk oncogenic subtypes, due to HIV-associated immunosuppression. Objective: To assess the prevalence and distribution profile of HPV subtypes in WLHA, correlating findings with CD4 levels and age group. Methods: A cross-sectional study was conducted with 184 WLHA receiving care at a public referral center in Juiz de Fora, Minas Gerais, from May 2021 to May 2022. Self-collected vaginal samples were analyzed by RT-PCR to detect HPV subtypes. Associations between HPV
View details →DOI: 10.5327/dst-2177-8264-1457 Negative / Null Result ReportOpen accessGeriatrics
Socheat Cheng, Tahreem Ghazal Siddiqui, Michael Gossop et al. · 2020 · BMC Geriatrics
Abstract Background Central nervous system depressant medications (CNSDs) such as opioid analgesics and sedative-hypnotics are commonly prescribed to older patients for the treatment of chronic pain, anxiety and insomnia. Yet, while many studies reported potential harms, it remains unknown whether persistent use of these medications is beneficial for older patients’ self-reported health-related quality of life (HRQoL). The present study clarified this knowledge gap through comparing HRQoL of hospitalized older patients with versus without using CNSD drugs for ≥4 weeks. Moreover, we explored th
View details →DOI: 10.1186/s12877-020-01838-8 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Karthikeyan R, Marimuthu G, Ramasubramanian C et al. · 2014 · Neuropsychiatric Disease and Treatment
Ramanujam Karthikeyan,1 Ganapathy Marimuthu,1 Chellamuthu Ramasubramanian,2 Gautham Arunachal,2 Ahmed S BaHammam,3 David Warren Spence,4 Daniel P Cardinali,5 Gregory M Brown,6 Seithikurippu R Pandi-Perumal7 1Department of Animal Behaviour and Physiology, School of Biological Sciences, Madurai Kamaraj University, Madurai, India; 2MS Chellamuthu Trust and Research Foundation, KK Nagar, Madurai, India; 3University Sleep Disorders Center, College of Medicine, National Plan for Science and Technology, King Saud University, Riyadh, Saudi Arabia; 4Independent researcher, Toronto, Ontario, C
Negative / Null Result ReportOpen access
Padma B Prabha, Jyothi P T · 2022 · Journal of Education Technology in Health Sciences
Structured interactive lectures (SIL) and Flipped classroom methods (FCM) are newer teaching learning methods which utilise pedagogical way of teaching. This study intends to compare efficacy of both methods in the understanding of…
View details →DOI: 10.18231/j.jeths.2021.019 Negative / Null Result ReportOpen accessVeterinary medicine
K. Wojdak-Maksymiec, M. Kmiec, J. Ziemak · 2006 · Veterinární Medicína
The study included 124 Polish Black-and-White dairy cows of various share of the Holstein-Friesian (HF) breed. Lactoferrin (LTF) gene polymorphism was obtained with PCR-RFLP method using EcoRI enzyme. Two alleles of LTF, A and B, were found in the studied population. Their frequencies were 67.74% and 32.56%, respectively. The alleles controlled the occurrence of three genotypes: AA, BB and AB, of frequencies equal to 37.90%, 2.42% and 59.68%, respectively. It was established that statistically significant associations exist between the somatic cell count (SCC) and LTF genotype, lactation month
View details →DOI: 10.17221/5512-vetmed Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Sofya Ilmer, Rubab Sohail, Sharon Hyman · 2026 · Frontiers in Endocrinology
IntroductionThis retrospective chart review investigated the relationship between 25-hydroxyvitamin D levels and the initial clinical and biochemical presentation of type 1 diabetes mellitus (T1DM) in children under 18 years of age, specifically: (1) presence or absence of diabetic ketoacidosis and the severity of diabetic ketoacidosis (DKA) - among those with DKA, and (2) beta-cell function.MethodsThis study included 99 children with new-onset Type 1 Diabetes Mellitus (T1DM). Patients were diagnosed at our pediatric endocrinology practice at Northwell Health between June 2023 and February 202
View details →DOI: 10.3389/fendo.2026.1814563 Negative / Null Result ReportOpen accessMedicine (General)
S Bakhti, S Latifi-Navid, S Zahri et al. · 2015 · Journal of Ardabil University of Medical Sciences
Background & objectives: Several studies have described VacA and CagA as the two important virulence determinants of Helicobacter pylori, which are associated with gastric ulcer (GU) and duodenal ulcer (DU). The aim of present study was to determine the associations of the i and d regions genotypes of H. pylori vacA gene and cagA status with GU and DU risk. Methods: A total of 177 isolates were cultured from the biopsies of Iranian patients with different geographic origins and genotyped. Data were collected and analyzed. Results: Frequency of the vacA i1, i2, i1i2, d1, and d2 alleles and cagA
Negative / Null Result ReportOpen accessGenetics
Erik Artur Cortinhas-Alves, Victor Henrique Botelho Lourenço, Andreza Juliana Moreira da Costa et al. · 2025 · Genetics and Molecular Biology
ABSTRACT The literature shows a correlation between ethnicity and pathogenic variants of the thyroid stimulating hormone receptor (TSHR) gene. Some of these polymorphisms may be risk factors for the development of primary congenital hypothyroidism (PCH). In this study, we investigated the relationship between the frequency of TSHR gene polymorphisms and the genetic influence of African, Amerindian, and European ancestry-informative markers in patients from an Amazonian population in Brazil who were diagnosed with PCH. The study was conducted on samples from 106 patients who were diagnosed with
View details →DOI: 10.1590/1678-4685-gmb-2024-0147 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Suming Dai, Ping Wang, Sijia Wang et al. · 2025 · Frontiers in Nutrition
BackgroundExisting epidemiological studies investigated the association between a single vitamin and hypertension. However, the potential relationship between the level of circulating multivitamins and blood pressure has not been explored. We aimed to investigate the association between multiple fat-soluble vitamin levels and blood pressure.MethodsA total of 2052 participants with essential hypertension were sampled nationwide. The plasma concentrations of fat-soluble vitamins (A, E, D, and K) were assessed using liquid chromatography coupled with the mass spectrometry method. Participants wer
View details →DOI: 10.3389/fnut.2024.1502139 Negative / Null Result ReportOpen accessPublic aspects of medicine
Farshad Teymoori, Hossein Farhadnejad, Ebrahim Mokhtari et al. · 2021 · BMC Public Health
Abstract Background Inflammation is a precursor of chronic disease, which is affected by lifestyle and dietary habits. Recently empirical dietary inflammatory patterns (EDIP), dietary inflammation scores (DIS), and lifestyle inflammation scores (LIS) were developed to indicate lifestyle and dietary contributions in systemic inflammation. The current study aimed to investigate the associations between these indices and the incidence of diabetes among Tehranian adults. Methods A total of 4624 individuals, aged 20–75 years, who were free of diabetes at baseline (2008–2011), were followed for 5.71
View details →DOI: 10.1186/s12889-021-11327-1 Negative / Null Result ReportOpen accessMedicine
Gieira S Jones, Heather Spencer Feigelson, Roni T Falk et al. · 2019 · PLoS ONE
Background Breast density, as estimated by mammography, is a strong risk factor for breast cancer in pre- and postmenopausal women, but the determinants of breast density have not yet been established. The aim of this study was to assess if urinary estrogens or gut microbiota alterations are associated with mammographic density in postmenopausal women. Methods Among 54 cancer-free, postmenopausal controls in the Breast and Colon Health study, we classified low- versus high-density women with Breast Imaging Reporting and Data System (BI-RADS, 5th edition) mammographic screening data, then asses
View details →DOI: 10.1371/journal.pone.0216114 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Babak B. Navi, Mitchell S. V. Elkind, Cenai Zhang et al. · 2025 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately 50% of strokes in patients with cancer are classified as cryptogenic after standard evaluation. Atrial cardiopathy could explain some cancer‐related cryptogenic strokes. However, the relationship between cancer and atrial cardiopathy is uncertain. Methods AND RESULTS We conducted a post hoc cross‐sectional analysis of baseline data collected from participants enrolled in ARCADIA (Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke), a clinical trial conducted from 2018 to 2023 at 185 sites. The analytical cohort presented herein included
View details →DOI: 10.1161/jaha.124.040543 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Shih-Hao Chen, Hung-Chieh Chang, Po-Wei Chiu et al. · 2023 · BMC Cardiovascular Disorders
Abstract Background Fever can occur after acute myocardial infarction (MI). The influence of body temperature (BT) after hospital arrival on patients with acute MI has rarely been investigated. Methods Patients who were diagnosed with acute MI in the emergency department (ED) of a tertiary teaching hospital between 1 January 2020 and 31 December 2020 were enrolled. Based on the tympanic temperature obtained at the ED triage, patients were categorized into normothermic (35.5°C-37.5°C), hypothermic ( 37.5°C) groups. The primary outcome was in-hospital cardiac arrest (IHCA), while the secondary o
View details →DOI: 10.1186/s12872-023-03372-y Negative / Null Result Report
Ade Harwoko, Lestari Kurniawati · 2022 · Jurnal Akademi Akuntansi
This study aims to determine changes in corporate tax aggressiveness after the application of Statement of Financial Accounting Standards (PSAK) 73. The sample of this research is the financial statements of pharmaceutical industry…
View details →DOI: 10.22219/jaa.v5i1.18732 Negative / Null Result ReportOpen accessBiochemistry
Rostami Shilan, Fathollahpour Asadollah, Abdi Mohammad et al. · 2018 · Journal of Medical Biochemistry
Background: There is a paucity of studies regarding oxidative balance and selenium (Se) status in congenital hypothyroidism. Recently, more attention has been given to the use of Se supplementation as a new treatment for thyroid disorders. Oxidative stress increases in different thyroid disorders and causes many pathological outcomes. The present study aimed to determine the serum prooxidant-antioxidant balance (PAB), Se, thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentration in congenital hypothyroidism (CH) patients and the association of their probable change with hematolo
Negative / Null Result ReportOpen accessPediatrics
Fatma Sargin, Mehmet Alçı, Büşra Kaygusuz Aydemir et al. · 2026 · BMC Pediatrics
Abstract Background Childhood epilepsy is one of the most common neurological disorders worldwide, significantly affecting cognitive, emotional, and social development. As caregivers often seek medical guidance online, the readability, understandability, and quality of internet-based patient education materials (IPEMs) are crucial for health literacy and decision-making. This study evaluates the readability, understandability, quality, and popularity of online pediatric epilepsy materials in relation to established health communication standards. Methods A Google search using the term ‘epileps
View details →DOI: 10.1186/s12887-026-06602-2 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng et al. · 2019 · Analytical Cellular Pathology
Recently, there has been an increasing interest in the potential clinical use of several inflammatory indexes, namely, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic-immune-inflammation index (SII). This study aimed at assessing whether these markers could be early indicators of pulmonary hypertension (PH) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A total of 185 patients were enrolled in our retrospective study from January 2017 to January 2019. Receiver operating characteristic curve (ROC) and area under the
View details →DOI: 10.1155/2019/5189165 Negative / Null Result ReportOpen accessNursing
Simone Maria Muniz da Silva Bezerra, Eduardo Tavares Gomes, Paulo César da Costa Galvão et al. · Revista Brasileira de Enfermagem
ABSTRACT Objective: To characterize relations between spiritual well-being and hope of patients in the preoperative period of cardiac surgery. Method: Exploratory cross-sectional study with quantitative approach, performed in the infirmaries of a reference hospital in cardiology. We evaluated 69 patients hospitalized in preoperative period of myocardial revascularization, valve repair or replacement. Results: We verified that patients hold relevant scores of hope and welfare in all areas, being the existential well-being significantly lower than the religious one. The average of the spiritual
View details →DOI: 10.1590/0034-7167-2016-0642 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Ovi Sofia, Muna Amalia, Herryanto Thomassawa et al. · 2024 · Interdisciplinary Perspectives on Infectious Diseases
Introduction. The imbalance of the immune response is an important factor contributing to the incidence of ocular toxoplasmosis (OT). Regulatory T cells (Treg) play a key role in maintaining the balance between Th1 and Th17 immune responses, while interleukin-27 (IL-27) levels are related to the differentiation of Th17 cells. This study analyzes the differences in the number of Treg cells and the level of IL-27 between OT patients and seropositive individuals without ocular lesions and its correlation with retinal lesion size. Methods. This analytic observational study, conducted for 8 months,
View details →DOI: 10.1155/2024/3495376 Negative / Null Result ReportOpen accessOrthopedic surgery
Neal Singleton, Vaughan Poutawera · 2017 · Journal of Orthopaedic Surgery
Aim: It has been reported in the literature that patients with poor preoperative mental health are more likely to have worse functional outcomes following primary total hip and knee arthroplasty. We could find no studies investigating whether preoperative mental health also affects length of hospital stay following surgery. The aim of this study was to determine whether preoperative mental health affects length of hospital stay and long-term functional outcomes following primary total hip and knee arthroplasty. We also aimed to determine whether mental health scores improve after arthroplasty
View details →DOI: 10.1177/2309499017718902 