Negative / Null Result ReportOpen accessMedicine
Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →DOI: 10.1016/j.fsisyn.2026.100691 Negative / Null Result Report
Lesmanawati DAS, Widiasta A, Ghrahani R et al. · 2026 · Preprint
Abstract Background Patients with systemic lupus erythematosus (SLE) are at increased risk of tuberculosis (TB) because of disease-related immune dysregulation and prolonged immunosuppressive therapy. Screening for latent TB infection…
View details →DOI: 10.21203/rs.3.rs-9728431/v1 Negative / Null Result ReportMedicine
Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →DOI: 10.1097/cji.0000000000000612 Negative / Null Result ReportMedicine
Costa M, Rodrigues P, Araújo B et al. · 2026 · Diagnostic microbiology and infectious disease
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity.…
View details →DOI: 10.1016/j.diagmicrobio.2026.117512 Negative / Null Result ReportMedicine
Li QX, Luo LZ · 2026 · BMC infectious diseases
Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are rare. Atypical clinical manifestations and the need for precise microbiological identification often result in misdiagnosis and underdiagnosis. Case…
View details →DOI: 10.1186/s12879-026-13549-3 Negative / Null Result ReportOpen accessMedicine
Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →DOI: 10.5114/kitp.2026.160677 Negative / Null Result ReportMedicine
Connolly M, McClelland L, Tannorella P et al. · 2026 · Prenatal diagnosis
Objective Prenatal genetic testing for imprinting disorders is rarely requested with the exception of Beckwith-Wiedemann syndrome (BWS) which is associated with specific ultrasound findings (e.g., placental mesenchymal dysplasia,…
View details →DOI: 10.1002/pd.70206 Failed Experiment ReportMedicine
Daix-Moreux M, El Hajj H, Schérier S et al. · 2026 · Gynecologic oncology
Objective Assess the accuracy of preoperative PET-CT in detecting para-aortic nodal metastasis in patients with locally-advanced cervical cancer, using routine laparoscopic para-aortic lymphadenectomy and evaluate its impact on patient…
View details →DOI: 10.1016/j.ygyno.2026.02.012 Failed Experiment Report
Kawamura T, Koyama S, Karaushi H et al. · 2026 · Preprint
Introduction: The Gram stain is a fundamental and widely used technique in clinical microbiology for its simplicity and diagnostic value, particularly in bacterial meningitis. However, its reliability can be compromised by contamination…
View details →DOI: 10.1099/acmi.0.001219.v1 Failed Experiment Report
Alkathiri O, Liberman M · 2026 · Preprint
Mediastinal staging remains a critical step in the management of non-small-cell lung cancer (NSCLC), as it directly impacts treatment planning, surgical decision-making, and overall prognosis. For many years, mediastinoscopy was considered…
View details →DOI: 10.20944/preprints202604.0470.v1 Negative / Null Result ReportMedicine
Ailun G, Li Y, Zhang D et al. · 2026 · Journal of medical case reports
Ovarian carcinosarcoma, also known as malignant mixed Müllerian tumor (MMMT), is a rare and highly aggressive gynecologic malignancy characterized by the presence of both epithelial and mesenchymal components. It predominantly affects…
View details →DOI: 10.1186/s13256-026-06253-y Negative / Null Result ReportMedicine
Schroeder TH, Eliwi Alsaffan M, Stäudle H et al. · 2026 · Journal of clinical medicine
Background: Blood cultures often yield negative results in critically ill patients, particularly after antimicrobial therapy has started. Plasma metagenomic next-generation sequencing enables culture-independent pathogen detection, but its…
View details →DOI: 10.3390/jcm15124434 Negative / Null Result ReportMedicine
Rhodes JM · 2026 · The British journal of nutrition
It is widely known that the short chain fatty acid (SFA) butyrate, generated mainly through fermentation of dietary fibre by anaerobic bacteria, has beneficial effects on health. Less widely known is that butyrate, at the concentration…
View details →DOI: 10.1017/s0007114526107247 Negative / Null Result ReportOpen accessMedicine
Wang H, Ardura MI, Oyeniran SJ et al. · 2026 · ASM case reports
Background Cytomegalovirus (CMV) continues to be a significant cause of morbidity and mortality in immunocompromised patients. Nucleic acid amplification tests (NAATs) are the preferred method for both diagnosing CMV infection and…
View details →DOI: 10.1128/asmcr.00159-25 Negative / Null Result ReportMedicine
Hinoshita M, Maeda Y, Kawai A et al. · 2026 · The Journal of toxicological sciences
The modified electron spin resonance (ESR)-based photosafety test (ESR-PT) is a non-animal prediction test using ESR spectroscopy that is applicable to hydrophobic and colored chemicals and the results show high concordance with existing…
View details →DOI: 10.2131/jts.51.1 Negative / Null Result ReportMedicine
Christopher-Stine L · 2026 · The Journal of rheumatology
Although statin-induced muscle toxicity was recognized, a subset of patients presented with severe, persistent necrotizing myopathy despite statin withdrawal. Recognized initially through the serendipitous aggregation of cases in the…
View details →DOI: 10.3899/jrheum.2026-0305 Negative / Null Result ReportOpen accessMedicine
Alvarez AM, Vega M, Valencia-Shelton F et al. · 2026 · Cureus
Background The evaluation of neonatal herpes simplex virus (HSV) includes HSV culture and/or polymerase chain reaction (PCR) of different surfaces, cerebrospinal fluid (CSF), and blood. However, the impact of blood HSV PCR for the…
View details →DOI: 10.7759/cureus.102996 Negative / Null Result Report
Alger JR, Gupta I, Farkouh L et al. · 2026 · Preprint
Background Prior neuroimaging suggests brain differences between children with attention deficit hyperactivity disorder due to prenatal alcohol exposure (ADHD+PAE) and non-exposed children with ADHD due to other, e.g., familial, causes…
View details →DOI: 10.64898/2026.05.25.26354065 Negative / Null Result ReportMedicine
Dellbrügge F, Schaumann N, Kruppa M et al. · 2026 · Pneumologie (Stuttgart, Germany)
Abstract We present the case of a 39-year-old Indian female patient diagnosed with tuberculous mastitis and lymph node tuberculosis. The patient had a history of tuberculosis infection treatment as a newborn. She initially presented with…
View details →DOI: 10.1055/a-2845-3440 Negative / Null Result ReportMedicine
Li X, Huang Y, Hao J et al. · 2026 · Current HIV research
Background Married Men who have Sex with Men (MSM) constitute a bridge population for HIV diffusion into low-risk groups, with spousal non-disclosure rates exceeding 60% in China. It will increase the risk of secondary transmission within…
View details →DOI: 10.2174/011570162x444930260409114355 Negative / Null Result ReportMedicine
Tsang SM, Merino Gutierrez V, Yu J et al. · 2026 · Veterinary sciences
Canine babesiosis caused by Babesia gibsoni is prevalent in Hong Kong. While molecular diagnosis via PCR is highly sensitive, it typically requires reference laboratory access, delaying clinical decisions. This study evaluated the…
View details →DOI: 10.3390/vetsci13060548 Negative / Null Result ReportMedicine
Hijaze E, Razi T, Arbel R et al. · 2026 · Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
Objective To evaluate the diagnostic performance of BioPlex 2200 multiplex immunoassay (BI) for detecting antinuclear antibodies (ANA), compared with the gold standard, the indirect immunofluorescence assay (IIF), as a screening…
View details →DOI: 10.1097/rhu.0000000000002372 Negative / Null Result ReportMedicine
Tri PM, Hung NT, Liet DH et al. · 2026 · Emergency radiology
Purpose To assess the diagnostic performance of computed tomography (CT) for predicting main pancreatic duct injury in surgically explored patients with distal pancreatic trauma. Methods We conducted a prospective single-center diagnostic…
View details →DOI: 10.1007/s10140-026-02504-z Negative / Null Result ReportMedicine
Wei XT, Zhu LY, Wu YL et al. · 2026 · Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Objective: To evaluate the screening performance and related factors of ultrasound for hepatic steatosis in community-based elderly populations using controlled attenuation parameter (CAP) measured by transient elastography as the…
View details →DOI: 10.3760/cma.j.cn112338-20250626-00436 Negative / Null Result Report
TEZCE A, DURMUŞ E · 2026 · Preprint
Abstract Purpose The objective of this study is to compare the diagnostic efficacy of Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) in detecting lumbar spondylolysis among patients presenting with chronic low back pain, and…
View details →DOI: 10.21203/rs.3.rs-9247900/v1 Negative / Null Result Report
Livorsi DJ, Ritter S, Lund BC et al. · 2026 · Preprint
Abstract Background: The pneumococcal urinary antigen test can help rapidly identify Streptococcus pneumoniae as the cause of community-acquired pneumonia (CAP). In this study, we assessed the utility of this test across an integrated…
View details →DOI: 10.21203/rs.3.rs-9267869/v1 Negative / Null Result ReportOpen accessMedicine
Zorlutuna Kaymak N, Pekel İ, Demir Tekol S et al. · 2026 · BMC ophthalmology
Purpose To evaluate the diagnostic utility and real-world clinical impact of polymerase chain reaction (PCR) analysis of aqueous humor (AH) and vitreous samples in patients with uveitis including suspected infectious and mixed…
View details →DOI: 10.1186/s12886-026-05002-5 Negative / Null Result ReportMedicine
Mangiameli G, Brascia D, Re Cecconi E et al. · 2026 · Updates in surgery
The role of surgery in malignant pleural mesothelioma (MPM) remains controversial, particularly after the negative results of the MARS 1 and 2 trials. Lung-sparing cytoreductive procedures such as extended pleurectomy/decortication (eP/D)…
View details →DOI: 10.1007/s13304-026-02666-y Negative / Null Result ReportOpen accessMedicine
Feng Q, Liu B, Liu H et al. · 2025 · Frontiers in microbiology
Background Accurately diagnosing central nervous system (CNS) infections remains challenging. This study aimed to evaluate the effectiveness of metagenomic next-generation sequencing (mNGS) in diagnosing suspected CNS infections and its…
View details →DOI: 10.3389/fmicb.2025.1689253 Failed Experiment ReportOpen accessMedicine
Patterson KN, Reynolds MM, Lueder GT · 2026 · American journal of ophthalmology case reports
Purpose To report our findings in a patient with an atypical case of supertemporal iris and retinal coloboma, and to assess its systemic associations and potential genetic causes. Observations A premature female infant born at 31 weeks…
View details →DOI: 10.1016/j.ajoc.2025.102488 