A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19902 results in Negative / Null Result Report · page 604 of 664
Casseb, de Campos, Loos et al. · 2026 · Epilepsia
There are several clinical and research applications for determining the amount of brain tissue resected after epilepsy surgery; however, manual segmentation of postoperative magnetic resonance imaging (MRI) is imprecise and…
Chang, Lee, Yoon et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
To compare the serial measurements of repaired labral height in the early and late postoperative periods and clinical outcomes between patients with Bankart lesions and those with anterior labroligamentous periosteal sleeve avulsion…
Liu, Cui, Sun et al. · 2026 · Quantitative imaging in medicine and surgery
Preoperative evaluation of histopathological features and biomarkers is critical for personalized treatment of rectal adenocarcinoma. Amide proton transfer-weighted (APTw) magnetic resonance imaging (MRI) is a promising noninvasive…
Mulay, Bhansali, Indurkar et al. · 2026 · Bioinformation
Early achievement of optimal interdental papilla fill around dental implants remains a clinical challenge affecting aesthetic outcomes in single-tooth replacement. Therefore, it is of interest to compare interdental papilla fill around…
Fukushi, Emori, Tsuchie et al. · 2026 · Cureus
Aggressive surgical resection with adequate margins is associated with improved local control and survival in selected patients with primary spinal sarcomas. However, anatomical constraints often preclude complete resection, and outcomes…
Benson, Gomez, DerAshodian et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
This study examines disability-related disparities in tooth loss and dental visits, and Medicaid dental service utilization across Nevada counties in 2022. A cross-sectional analysis of the 2022 Behavioral Risk Factor Surveillance System…
Rode, Wolf, Bolan et al. · 2026 · Childhood obesity (Print)
This clinical trial evaluated hepatic fat content and weight loss in adolescents with severe obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) following short-term meal replacement therapy (MRT). Adolescents aged…
Kohzai, Yamamoto, Matsushita et al. · 2026 · Diagnostics (Basel, Switzerland)
Objectives : Whereas irreversible compression of Digital Imaging and Communications in Medicine (DICOM) files can reduce data size, research on its impact on diagnostic ability when using artificial intelligence (AI) software is limited.…
Bosbach, Montazeri, Senge et al. · 2026 · Diagnostics (Basel, Switzerland)
Purpose: Large language models (LLMs) may reduce administrative workload in radiology by automating structured diagnostic extraction from text reports. This study evaluates the accuracy of ChatGPT-4.0 when extracting correct diagnoses from…
Paternostro, Joura, Postl et al. · 2026 · Journal of clinical medicine
Background/Objectives: Large loop excision of the transformation zone (LLETZ) is used as a standard treatment for cervical dysplasia. Although obesity is associated with reduced cervical screening participation and may complicate…
Astan, Balta, Zengin et al. · 2026 · Journal of clinical medicine
Background/Objectives: Paprosky Type IIC acetabular defects encountered during revision total hip arthroplasty (rTHA) present substantial challenges in terms of surgical planning and implant stability. This study evaluates the outcomes of…
Wegner, Warnke, Buschmann et al. · 2026 · Journal of clinical medicine
Background/Objectives : Post-traumatic joint contracture (PTJC) is a common complication in orthopedic surgery characterized by fibrosis and restricted joint mobility. Previous work by our multi-arm study demonstrated that nintedanib…
Ozalp, Yolcu, Uyar et al. · 2026 · Journal of clinical medicine
Background: The erector spinae plane block (ESPB) is a commonly used interventional method in the treatment of post-herpetic neuralgia (PHN). ESPB can be performed under the guidance of ultrasound or fluoroscopy, and there are limited data…
Merluzzi, Lepri, Lidano et al. · 2026 · Animals : an open access journal from MDPI
The Anatomage Table Vet (ATV) is a digital tool that may facilitate the understanding of complex structures and improve visuospatial skills. This study evaluated the effectiveness of the ATV as a review method prior to cadaveric dissection…
Fu, Xiao, Ma et al. · 2026 · Animals : an open access journal from MDPI
Digestive tract structure is a key indicator of fish health and environmental adaptation, while seasonal dynamics of the gut microbiota reflect host responses to environmental changes. In this study, the digestive tract microstructure of…
Moosavi, Khorakian, Sedaghati et al. · 2026 · BMC oral health
Severe caries in mixed dentition frequently affects mandibular first permanent molars, often necessitating full-coverage restorations. Stainless steel crowns (SSCs) and porcelain-fused-to-metal (PFM) crowns are among the most commonly used…
Yue, Kong, Huang et al. · 2026 · BMC cancer
The optimal timing for thermal ablation (TA) in patients with colorectal liver metastases (CRLM) eligible for local curative therapy remains undefined. This study aimed to evaluate the impact of time to ablation (TTA) on long-term survival…
Roberts, Waddell, Atkins et al. · 2026 · The New Zealand medical journal
Our aim was to determine the 30- and 90-day all-cause mortality of healthcare-associated Staphylococcus aureus bacteraemia (HA-SAB) and determine mortality risk factors. We collected HA-SAB events from 1 July 2022 to 30 June 2024. Patient…
McFarland, Sihra, Walker et al. · 2026 · Journal of racial and ethnic health disparities
To evaluate Black birthing people's knowledge of American Academy of Pediatrics (AAP) infant safe sleep recommendations over time in the context of a substantial, county-wide, tailored public health initiative against infant mortality.…
Benyamini, Khan, Elmenawi et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly utilised for metabolic optimisation in surgical patients. Their effect on postoperative patient-reported outcomes (PROMs) and satisfaction following primary total hip…
Kamagaté, Jusot, Mory et al. · 2026 · Therapeutic advances in drug safety
In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. This study aimed to evaluate the quality of adverse…
Saeed, Jalal · 2026 · Pulmonary medicine
The COVID-19 pandemic, caused by SARS-CoV-2, has led to significant global mortality and morbidity. Angiotensin-converting Enzyme 2 (ACE2) has been identified as the primary receptor for viral entry into host cells and is believed to play…
Mohammed, Naser, Abozaid · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Composite resin placement technique may influence marginal integrity, polymerization stress distribution, and long-term clinical performance of posterior restorations. This randomized controlled clinical trial evaluated the 24-month…
Niu, Bao, Zhao · 2026 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
This study aimed to systematically evaluate the efficacy and safety of different doses of domperidone (DOM) combined with esomeprazole (ESM) in the treatment of reflux esophagitis, providing a basis for precise clinical medication. This…
Shi, Yuan, Gao et al. · 2026 · Journal of neuroengineering and rehabilitation
Transcranial magnetic stimulation (TMS), as a non-invasive neurostimulation technique, modulates neural activity by applying electromagnetic fields to specific areas of the brain. It is clinically used for several approved indications,…
Yakıt Yeşilyurt, Birinci Olgun, Dağ et al. · 2026 · BMC women's health
Breathing exercises may modulate dysmenorrhea by enhancing relaxation and eliciting analgesic effects. This study investigated the effects of Pelvic Floor Muscle Training (PFMT) with or without Dynamic Neuromuscular Stabilization…
Chen, Song, Zang et al. · 2026 · BMC anesthesiology
Right lateral thoracotomy cardiac surgery induces postoperative atelectasis due to cardiopulmonary bypass (CPB), patient positioning, and mechanical ventilation. Fixed positive end-expiratory pressure (PEEP) may fail to meet pediatric…
Yıldız, Çalış, Dokuz et al. · 2026 · Psychiatry research
This study examined differences in choroidal structural parameters, including the choroidal vascularity index, among patients with schizophrenia, bipolar disorder, and healthy controls. This cross-sectional study included 40 patients with…
Chen, Yi, Cao et al. · 2026 · Neurology
The efficacy of endovascular treatment for acute large vessel occlusion strokes has been demonstrated, but whether it can improve functional outcomes in patients with acute ischemic stroke (AIS) who only present with severe large vessel…
Bejarano, Hull, Young et al. · 2026 · PloS one
We exploit state-level policy changes for physical therapy direct access to estimate the effect of enacting direct access physical therapy policy on per-capita opioid pill volume (PCPV) and opioid-related deaths (ORD) compared to states…