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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 604 of 676

Negative / Null Result ReportOpen accessMedicine

Diffusion kurtosis imaging for detecting renal functional changes in glomerulonephritis: a longitudinal experimental study.

Liu J, Wu Y, Yang D et al. · 2026 · BMC medical imaging

BACKGROUND: Glomerulonephritis (GN) is a major contributor to chronic kidney disease, highlighting the need for reliable biomarker to monitor GN. This study aimed to evaluate the potential of diffusion kurtosis imaging (DKI) for dynamic…

View details →DOI: 10.1186/s12880-026-02197-3
Negative / Null Result ReportMedicine

Comparison of academic performance of primary school children presenting with strabismus and/or amblyopia in Nigeria with age- and sex-matched classmates.

Ojinnaka GC, Okoye OI, Ojinnaka NC et al. · 2026 · Journal of tropical pediatrics

To compare the academic performance of urban primary school children with strabismus and/or amblyopia seen at the Eye Clinic of University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu, Nigeria, with that of their controls. In…

View details →DOI: 10.1093/tropej/fmag027
Negative / Null Result ReportMedicine

[Effects of Salt-tolerant Rice Cultivation on Organic Carbon Pool and Carbon Conversion Enzyme Activities in Coastal Saline Soil].

Ji RT, Xie XF, Jia ZY et al. · 2026 · Huan jing ke xue= Huanjing kexue

Cultivating salt-tolerant rice (STR) is an effective approach to ameliorating coastal saline soils (CSL). In this study, the CSL without STR cultivation served as the control (CK), while soils with different rice cultivation years (1-5…

View details →DOI: 10.13227/j.hjkx.202411085
Negative / Null Result ReportMedicine

Trueness and precision of direct-printed and thermoformed clear aligners after artificial saliva exposure: A comparative in vitro study.

Dantagnan CA, Salem C, Charavet C et al. · 2026 · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

Introduction This study aimed to compare the effect of artificial saliva (AS) aging on the trueness and precision of direct-printed aligners vs thermoformed aligners. Methods Four types of aligners were manufactured from the same reference…

View details →DOI: 10.1016/j.ajodo.2025.11.021
Negative / Null Result Report

Diagnostic accuracy of anterior joint space widening on CBCT for identifying anterior disc displacement: a retrospective study using MRI as the reference standard

Chen Z, He S, Li C et al. · 2026 · Preprint

Abstract Objectives To evaluate the diagnostic accuracy of anterior joint space widening on Cone Beam Computed Tomography (CBCT) for identifying anterior disc displacement (ADD) of the temporomandibular joint (TMJ), using Magnetic…

View details →DOI: 10.21203/rs.3.rs-9526187/v1
Negative / Null Result ReportOpen accessMedicine

Assessment of Orofacial Function After Mandibular Angle Harmonization with Hyaluronic Acid: A Longitudinal Observational Study.

Bettiol NB, de Carvalho FA, Siessere S et al. · 2026 · Dentistry journal

Background: The relationship between facial aesthetic procedures and changes in the stomatognathic system has attracted increasing interest, motivating investigations into their functional and structural impacts. This longitudinal…

View details →DOI: 10.3390/dj14040241
Negative / Null Result ReportMedicine

Is segmentation solved? An evaluation of vision foundation models for head and neck tumor segmentation.

Baldeon-Calisto M, Perez-Pérez N, Guevara C · 2026 · Physics in medicine and biology

Objective. Vision foundation models (FMs) have shown strong potential for adapting to diverse downstream tasks without specialized fine-tuning. However, their performance in head and neck cancer (HNC) tumor segmentation remains…

View details →DOI: 10.1088/1361-6560/ae6af8
Negative / Null Result Report

Short-term memory and the integration of syntactic and semantic information in sentence processing: Evidence from a case of right-hemisphere language dominance

Ansorena X, Quiñones I, Hernandez M et al. · 2026 · Preprint

Purpose: We present the clinical case of AB, a right-handed individual who experienced a stroke affecting the right temporo-parietal cortex, resulting in phonological short-term memory (pSTM) impairment. Functional MRI revealed…

View details →DOI: 10.31234/osf.io/fx7ak_v2
Negative / Null Result ReportMedicine

In Vitro Evaluation of the Fracture Resistance of CAD/CAM-Manufactured Zirconia Crowns on Primary Teeth: A Comparison of Two Different Cement Types and Gap Widths.

Güngör İlhan GM, Erdoğan Y, Özbey İpek H et al. · 2026 · Nigerian journal of clinical practice

Background This study aimed to evaluate the effect of different cement types on the fracture strength of zirconia crowns fabricated at varying occlusal cement gap widths for primary molars using a computer-aided design and manufacturing…

View details →DOI: 10.4103/njcp.njcp_380_25
Negative / Null Result ReportMedicine

Foliar application of inorganic fertilizers mitigates mercury and methylmercury accumulation in dryland Crops: A plant-soil-microorganism synergistic regulation.

Luo G, He T, Yin D et al. · 2026 · Journal of environmental management

Foliar application technology has received considerable research attention due to its potential to mitigate the accumulation of heavy metals such as cadmium and lead in crops. However, to date, there are very few inorganic foliar sprays…

View details →DOI: 10.1016/j.jenvman.2026.128593
Negative / Null Result ReportMedicine

The relationship between pulmonary hypertension and graft vascular resistance and rejection in liver transplant patients.

Yagdiran B, Kirisci B, Cekmen N et al. · 2026 · BMC pulmonary medicine

Purpose Pulmonary hypertension (PH) is associated with systemic hemodynamic changes that may influence graft perfusion following liver transplantation (LT). In this study, we aimed to evaluate whether pre-transplant PH risk, as estimated…

View details →DOI: 10.1186/s12890-026-04351-7
Negative / Null Result ReportMedicine

Global Postural Re-Education Versus Deep Neck Flexor Activation on Chronic Nonspecific Neck Pain with Forward Head Posture.

Abd Elhamed HB, Mohamed Ahmed EA, Youssif EF et al. · 2026 · Journal of clinical medicine

Background and Objectives : Chronic nonspecific neck pain (NSNP) is among the most common musculoskeletal disorders. Global postural re-education (GPR) might be effective in decreasing neck pain (NP) and dysfunction and improving forward…

View details →DOI: 10.3390/jcm15124833
Negative / Null Result ReportMedicine

Harnessing caffeic acid for the green synthesis of gold nanoparticles: Exploring their biological efficacy and hemocompatibility.

Chahardoli A, Mostafaei A · 2026 · Scientific reports

Caffeic acid (CA) biomolecule was applied for the biofabrication of AuNPs (CA-AuNPs) as a reducing and stabilizing agent under optimal conditions. This study aimed to investigate the biological efficacy of CA-AuNPs by testing their…

View details →DOI: 10.1038/s41598-026-50713-w
Negative / Null Result ReportMedicine

ACL Reconstruction for Combined ACL/MCL Injuries in Professional Soccer and Rugby Players: No Difference in Career Longevity Compared to Uninjured Matched Controls.

Jones M, Motesharei A, Abdul W et al. · 2026 · The American journal of sports medicine

Background Combined anterior cruciate ligament (ACL) and medial collateral ligament (MCL) injuries are common in professional sport, but there is little evidence available regarding the long-term impact of them on players' sporting…

View details →DOI: 10.1177/03635465261448234
Negative / Null Result ReportMedicine

Differential effects of primary and latent syphilis co-infection on immune reconstitution and virological failure in HIV-positive adults on ART.

Shi L, Liu X, Qiu T et al. · 2026 · BMC public health

Background HIV and syphilis are sexually transmitted diseases (STDs) that share transmission routes and risks factors. Many countries face the dual challenge of HIV and syphilis epidemics. Co-infection can mutually accelerate disease…

View details →DOI: 10.1186/s12889-026-28199-y
Negative / Null Result ReportOpen accessMedicine

Bacteria in stable fly (Diptera: Muscidae) feces inform foraging decisions of conspecific flies.

Hung E, Negraeff A, Watson C et al. · 2026 · Journal of medical entomology

Blood-feeding stable flies, Stomoxys calcitrans (L.), are reportedly attracted to conspecific feces. We investigated whether stable flies are attracted to fly feces-derived bacteria, and whether attraction varies with bacterial species and…

View details →DOI: 10.1093/jme/tjag084
Negative / Null Result ReportMedicine

Impacts of a Gamified Nutrition and Physical Activity Curriculum for High Schoolers from Communities with Low Income: Rev It Up!

Bastian GE, Desai-Shah H, Fitzgerald N et al. · 2026 · Journal of nutrition education and behavior

Objective Evaluate the impacts of an evidence-based, school-based, gamified nutrition education curriculum (Rev It Up!) for high schoolers from communities with low income. Methods Secondary analysis of 2021-2022 New Jersey Expanded Food…

View details →DOI: 10.1016/j.jneb.2026.04.009
Negative / Null Result Report

Effects of Exogenous Fibrolytic Enzymes on Growth Performance, Nutrient Digestibility, Haematological and Serum Biochemical Indices, and Manure Output of Kano Brown Bucks

Ibrahim RS, Abbas MW, Nasiru A · 2026 · Preprint

Abstract Background: Exogenous enzymes are increasingly used in ruminant nutrition to improve feed utilization and reduce nutrient losses. This study evaluated the the effects of different exogenous enzyme inclusions on growth performance,…

View details →DOI: 10.21203/rs.3.rs-8833196/v1
Negative / Null Result ReportMedicine

The Association of Energy Distribution Between Dinner and Breakfast With Depressive Symptoms in Early Pregnancy.

Jiang Y, Luo J, Zheng L et al. · 2026 · The journal of obstetrics and gynaecology research

Aim To examine the association between the distribution of energy and macronutrients between dinner and breakfast and depressive symptoms in early pregnancy. Methods This study used baseline data from a maternity cohort conducted in Wuhan,…

View details →DOI: 10.1111/jog.70298