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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 589 of 676

Negative / Null Result ReportMedicine

Eating Behavior Traits and Success in Dietary Changes in Men with Prediabetes - the T2D-GENE Intervention.

Koivu N, Lankinen M, Schwab U · 2026 · Health education & behavior : the official publication of the Society for Public Health Education

Sustained dietary change is essential for type 2 diabetes prevention, yet most Finnish men do not follow dietary recommendations. Eating behavior traits such as cognitive restraint, uncontrolled eating, and emotional eating may influence…

View details →DOI: 10.1177/10901981251411226
Negative / Null Result ReportMedicine

Embryo morphokinetics and PGT-A outcomes in recurrent pregnancy loss cases.

Aygun TM, Ozkara G, Balin Duzguner IN et al. · 2026 · Zygote (Cambridge, England)

Recurrent pregnancy loss (RPL) is a clinically important condition in women undergoing assisted reproductive technologies (ART). This study evaluated embryo morphology and morphokinetic parameters using time-lapse monitoring (TLM) and…

View details →DOI: 10.1017/s0967199426100355
Negative / Null Result ReportMedicine

Longitudinal Association Between Sprint and Jump Performance in Youth Male Soccer Players: Implications for Talent Development.

Laas MM, Wright M, Enright K et al. · 2026 · Research quarterly for exercise and sport

This study analyzed the longitudinal relationship between short sprints and counter movement jump (CMJ) in youth male soccer players. Players ( n = 304, age 13.0 ± 1.9 years) from a Scottish soccer academy completed sprints (10 m, 20 m…

View details →DOI: 10.1080/02701367.2025.2594709
Negative / Null Result ReportMedicine

Predicting structure- and control-based parental feeding practices among families with low-income: An ecological approach.

Barton JM, Eagleton SG, Reyes LI et al. · 2026 · Appetite

Parental feeding practices (hereafter referred to as feeding practices) influence child weight outcomes, but few studies have identified which obesogenic risk factors shape their feeding practices using an ecological approach, especially…

View details →DOI: 10.1016/j.appet.2026.108518
Negative / Null Result ReportMedicine

The effect of childhood trauma on the severity of depressive symptoms and drug resistance in major depressive disorder - results from the international PROMPT study.

Ferensztajn-Rochowiak E, Rybakowski F, Michalak M et al. · 2026 · Journal of affective disorders

Objectives Treatment resistance in major depressive disorder (MDD) affects nearly 30% of patients, and early childhood trauma (CT) may play a significant role in its development. The international PROMPT project investigates the…

View details →DOI: 10.1016/j.jad.2026.121859
Negative / Null Result ReportMedicine

Temperature and precipitation mismatches increase infection risk in amphibians.

Thumsová B, Martínez-Silvestre A, Pérez-Vallejo M et al. · 2025 · Current biology : CB

The thermal mismatch hypothesis (TMH), the notion that cool- and warm-adapted hosts have higher infection risk during unusually warm and cool spells, respectively, was recently proposed to explain how temperature shifts driven by climate…

View details →DOI: 10.1016/j.cub.2025.07.053
Negative / Null Result ReportMedicine

ICANS mitigation in high-risk elderly patients treated with CD28 co-stimulatory anti-CD19 CAR-T cells using a standardization protocol: a pilot study.

Fridberg G, Amit O, Sherf Y et al. · 2026 · Haematologica

CAR-T has transformed relapsed/refractory LBCL treatment, with CD28-based products yielding rapid responses but higher ICANS rates. With Axicabtagene-ciloleucel and Brexucabtagene-autoleucel, overall and severe ICANS reach 78% and 35%,…

View details →DOI: 10.3324/haematol.2025.288954
Negative / Null Result ReportMedicine

Does Red Cell Distribution Width Have a Predictive Role in Anastomotic Leak after Right Hemicolectomy for Colon Cancer?

Sevik HO, Aytepe O, Kilic MK et al. · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A

Introduction Red cell distribution width (RDW) has recently emerged as a potential biomarker reflecting nutritional and inflammatory status in surgical oncology. While anastomotic leakage (AL) remains a devastating complication after right…

View details →DOI: 10.1177/10926429251410882
Negative / Null Result Report

Return of Threat Expectancy Likelihood After an Exposure Exercise as Dynamic Predictor of Intervention Outcome in Fear of Public Speaking

Bouwman V, Pittig A, Engelhard I et al. · 2025 · Preprint

Although exposure-based Cognitive Behavioral Therapy is generally effective for anxiety disorders, many people do not benefit. A better understanding of treatment predictors is required. This study investigated whether the dynamics of…

View details →DOI: 10.31234/osf.io/6s23z_v2
Negative / Null Result Report

Precision of reaches and proprioception in motor control and adaptation

Henriques DY, Gastrock RQ, Hart BM' · 2025 · Preprint

Abstract How do precision of movement and proprioception influence motor control and adaptation? Several theories—such as the exploration-exploitation hypothesis—propose that variability plays a key role in motor performance and learning.…

View details →DOI: 10.21203/rs.3.rs-7713663/v1
Negative / Null Result Report

Bridging Perspectives: The Impact of Teacher and Student Ratings of Social-Emotional and Instructional Characteristics on Student Outcomes

Scheirlinckx J, Dupré S, De Fruyt F · 2025 · Preprint

Teachers' social-emotional and instructional (SEI) characteristics shape classroom functioning and student outcomes, yet most research relies exclusively on teacher self-reports, potentially overlooking discrepancies between teachers'…

View details →DOI: 10.31234/osf.io/3tm2f_v1
Negative / Null Result ReportMedicine

Effects of Corticotropin-Releasing Factor 1 Receptor Antagonism on In Vivo Dentate Gyrus Long-Term Potentiation in the TgF344-AD Rat Model of Alzheimer's Disease.

Reyna NC, Hamilton DA · 2026 · Hippocampus

Alzheimer's disease (AD) is characterized by irreversible neurobiological deterioration and cognitive impairment. AD patients exhibit stress system abnormalities including upregulation of the corticotropin releasing factor type 1 receptor…

View details →DOI: 10.1002/hipo.70103
Negative / Null Result ReportMedicine

Prolonged Mismatch Negativity Latencies in Intensive Care Unit Patients With Active Delirium.

Chen YC, Chang HJ, Chang CW et al. · 2026 · Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

Introduction Delirium is a common and serious complication in critically ill patients, associated with higher mortality, prolonged intensive care unit (ICU) stays, and cognitive impairments. Furthermore, renal dysfunction is a…

View details →DOI: 10.1097/wnp.0000000000001238
Negative / Null Result Report

Prestimulus α Band Power and Phase Predict Visual Awareness

Li X, Lyu Y · 2025 · Preprint

Abstract People are often unaware of objects that are easily aware of at other times. Because the visual target itself is constant, this change may be attributed to fluctuations in cortical excitability. It is measured mainly by the power…

View details →DOI: 10.21203/rs.3.rs-6624226/v1
Negative / Null Result ReportMedicine

Biopsychosocial risk factors for the transition from acute to chronic back pain: A prospective cohort study.

Engelmann P, Busmann M, Löwe B et al. · 2026 · Journal of psychosomatic research

Background Biopsychosocial mechanisms are assumed to underlie the chronification of back pain; however, potentially relevant factors have mainly been examined in isolation rather than within comprehensive aetiological models. This study…

View details →DOI: 10.1016/j.jpsychores.2025.112500
Negative / Null Result ReportMedicine

Clinical outcomes and haemodynamic response after blinded stress assessment of moderate aortic stenosis.

Eerdekens R, Johnson NP, Adrichem R et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Background Assessing aortic stenosis (AS) haemodynamics under stress may distinguish physiological responses beyond traditional severity metrics. Aims We aimed to evaluate symptomatic patients with moderate AS and preserved left…

View details →DOI: 10.4244/eij-d-25-01006
Negative / Null Result ReportOpen accessMedicine

A longitudinal investigation of performance and injury outcomes associated with disordered eating in elite athletes.

Fatt SJ, Hay P, George E et al. · 2025 · Sports medicine - open

Background Disordered eating is common in elite athletes and may be motivated by perceived performance advantages associated with becoming leaner. However, few studies have examined the performance outcomes associated with disordered…

View details →DOI: 10.1186/s40798-025-00927-5
Negative / Null Result ReportMedicine

Temperature at admission and mortality in older adults with infection: Limited prognostic value in non-sepsis cases.

Nielsen FE, Abdullah OB, Chafranska L et al. · 2026 · The American journal of emergency medicine

Background Temperature abnormalities are established prognostic markers in sepsis, but their predictive value in older adults with infection without sepsis remains unclear. Objective To examine the association between arrival temperature…

View details →DOI: 10.1016/j.ajem.2026.01.045