Negative / Null Result ReportMedicine
O'Shaughnessy J, Brufsky AM, Layeequr Rahman R et al. · 2026 · JCO precision oncology
Purpose Randomized trials have not demonstrated clear benefit from anthracyclines for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (EBC). The MammaPrint 70-gene…
View details →DOI: 10.1200/po-25-01285 Negative / Null Result ReportMedicine
Xiao H, Warner E, Ryan J et al. · 2026 · Cancer causes & control : CCC
Purpose Cancer-related cognitive impairment (CRCI) is a common concern among breast cancer (BC) patients receiving chemotherapy, yet predictors of short-term cognitive change remain unclear. This study examined whether baseline…
View details →DOI: 10.1007/s10552-026-02165-w Negative / Null Result Report
Tsokolas ZE, Asante I, Tsiknia AA et al. · 2026 · Preprint
Abstract Apolipoprotein E ε4 (APOE4) is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), yet whether its pathogenic effects are driven by HDL lipidation state or by elevated APOE4 levels in the CNS remains…
View details →DOI: 10.21203/rs.3.rs-9349576/v1 Negative / Null Result ReportMedicine
William JB, Chieng D, Crowley R et al. · 2026 · JACC. Clinical electrophysiology
Background Left atrial (LA) enlargement is commonly used in patient selection for catheter ablation. However, its role in predicting postablation outcomes in persistent atrial fibrillation (AF) remains uncertain. Objectives The study goal…
View details →DOI: 10.1016/j.jacep.2026.04.019 Negative / Null Result ReportMedicine
Alpert E, Kaplan A, Nelson D et al. · 2026 · Psychological trauma : theory, research, practice and policy
Objective Among patients with co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUDs), little is known about early PTSD treatment processes, including treatment preference and outcome expectancy. This study…
View details →DOI: 10.1037/tra0002161 Negative / Null Result ReportMedicine
Cohen H, Toro D, Zuluaga D et al. · 2026 · Clinical transplantation
Introduction To evaluate donor-stratified graft and patient survival following kidney transplantation (KT) for lithium-associated end-stage kidney disease (ESKD). Methods This retrospective analysis utilized the Organ Procurement and…
View details →DOI: 10.1111/ctr.70563 Negative / Null Result ReportMedicine
Yang L, Zhang H, Wei Y et al. · 2026 · American journal of hematology
Immunosuppressive therapy (IST) is the standard treatment for acquired pure red cell aplasia (aPRCA), but predictors of treatment response and long-term prognosis remain unclear. The clinical significance of somatic mutations in aPRCA is…
View details →DOI: 10.1002/ajh.70311 Negative / Null Result ReportOpen accessMedicine
Vellore AJ, Bhatia S, Kann MR et al. · 2026 · JMIR XR and spatial computing
Background Augmented reality (AR) can provide risk-free training for medical trainees, yet little is known about which learner characteristics facilitate adoption or inform training design. Objective We aimed to identify which learner…
View details →DOI: 10.2196/81236 Negative / Null Result ReportMedicine
Denfeld QE, Hiatt SO, Dieckmann NF et al. · 2026 · The Journal of cardiovascular nursing
Many adults with heart failure (HF) are physically frail, and HF self-care behaviors, especially symptom monitoring and management (SMM), may affect physical frailty; however, the association between SMM behaviors and physical frailty has…
View details →DOI: 10.1097/jcn.0000000000001342 Negative / Null Result ReportMedicine
Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…
View details →DOI: 10.1177/10781552251415528 Negative / Null Result Report
Chernetska V, Millgram Y · 2025 · Preprint
Background: Suicidal thoughts affect approximately 10% of the population during their lifetime. In about one-third of cases, these thoughts persist, contributing to poorer health and elevated suicide risk. Emotion regulation deficits were…
View details →DOI: 10.31234/osf.io/exkzp_v1 Negative / Null Result ReportOpen accessMedicine
Yakubu YH, Saani MM · 2026 · Nursing open
Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…
View details →DOI: 10.1002/nop2.70662 Negative / Null Result ReportOpen accessMedicine
Kumar N, Gomes PL, Jett S et al. · 2025 · Laryngoscope investigative otolaryngology
Objectives Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND…
View details →DOI: 10.1002/lio2.70217 Negative / Null Result ReportOpen accessMedicine
Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology
Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…
View details →DOI: 10.1002/acr2.90030 Negative / Null Result Report
Munns A, Feron J, Duda J et al. · 2026 · Preprint
Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…
View details →DOI: 10.31234/osf.io/gk74p_v1 Negative / Null Result ReportMedicine
Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis
Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…
View details →DOI: 10.1080/15504263.2025.2606022 Negative / Null Result ReportMedicine
Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)
Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…
View details →DOI: 10.1016/j.clinbiomech.2026.106768 Negative / Null Result Report
Hart SN, Bergamaschi TS · 2025 · Preprint
Objective To develop and validate an agent-based Large Language Model (LLM) system for extracting structured data from breast cancer synoptic pathology reports and assess the performance gap between synthetic and real-world validation.…
View details →DOI: 10.1101/2025.11.25.25340989 Negative / Null Result Report
Chira A, de la Fuente Garcia S · 2025 · Preprint
Morality is deeply rooted in the context of relationships. Yet the influence of relational factors, such as attachment, on moral concerns remains largely unexplored. Nonetheless, recent scholarship has shed some light on the connection…
View details →DOI: 10.31234/osf.io/rxpyn_v2 Negative / Null Result ReportMedicine
Carreras JP, Carney BC, Lee D et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association
Skin fibrosis, especially hypertrophic scars (HTS), remains understudied with few effective treatments. Studying HTS is challenging due to its natural tendency to improve over time, making it hard to separate intervention effects. This…
View details →DOI: 10.1093/jbcr/irag012 Negative / Null Result ReportMedicine
Rabinowitz JA, Masyn K, Thomas N et al. · 2026 · Drug and alcohol dependence
Objective Using a latent change score modeling approach, we tested the bidirectional relationships between spirituality and craving during the first month of substance use disorder (SUD) treatment. Specifically, we examined whether higher…
View details →DOI: 10.1016/j.drugalcdep.2026.113116 Negative / Null Result ReportMedicine
Jubas S, Collins K, Obara K et al. · 2026 · Transplantation and cellular therapy
Background Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for hematologic malignancies. However, relationships between donor chimerism and clinical outcomes remain poorly characterized. Objective The…
View details →DOI: 10.1016/j.jtct.2026.06.024 Negative / Null Result ReportMedicine
Abaei E, Martin P · 2026 · Aging & mental health
Objectives Using data from the Health and Retirement Study (1992-2020), this study investigates how cognitive function and its longitudinal changes influence trajectories of depressive symptoms among oldest-old adults. Method Latent growth…
View details →DOI: 10.1080/13607863.2026.2612728 Negative / Null Result ReportMedicine
Koivu N, Lankinen M, Schwab U · 2026 · Health education & behavior : the official publication of the Society for Public Health Education
Sustained dietary change is essential for type 2 diabetes prevention, yet most Finnish men do not follow dietary recommendations. Eating behavior traits such as cognitive restraint, uncontrolled eating, and emotional eating may influence…
View details →DOI: 10.1177/10901981251411226 Negative / Null Result ReportMedicine
Aygun TM, Ozkara G, Balin Duzguner IN et al. · 2026 · Zygote (Cambridge, England)
Recurrent pregnancy loss (RPL) is a clinically important condition in women undergoing assisted reproductive technologies (ART). This study evaluated embryo morphology and morphokinetic parameters using time-lapse monitoring (TLM) and…
View details →DOI: 10.1017/s0967199426100355 Negative / Null Result ReportMedicine
McNeil J, Logel C, Rehman US · 2026 · Journal of sex research
Sexual problems in relationships are negatively correlated with sexual satisfaction, but the direction of this relationship remains unclear. Although most theorizing posits that changes in sexual problems precede changes in sexual…
View details →DOI: 10.1080/00224499.2025.2593516 Negative / Null Result ReportMedicine
Laas MM, Wright M, Enright K et al. · 2026 · Research quarterly for exercise and sport
This study analyzed the longitudinal relationship between short sprints and counter movement jump (CMJ) in youth male soccer players. Players ( n = 304, age 13.0 ± 1.9 years) from a Scottish soccer academy completed sprints (10 m, 20 m…
View details →DOI: 10.1080/02701367.2025.2594709 Negative / Null Result ReportMedicine
Barton JM, Eagleton SG, Reyes LI et al. · 2026 · Appetite
Parental feeding practices (hereafter referred to as feeding practices) influence child weight outcomes, but few studies have identified which obesogenic risk factors shape their feeding practices using an ecological approach, especially…
View details →DOI: 10.1016/j.appet.2026.108518 Negative / Null Result ReportMedicine
Ferensztajn-Rochowiak E, Rybakowski F, Michalak M et al. · 2026 · Journal of affective disorders
Objectives Treatment resistance in major depressive disorder (MDD) affects nearly 30% of patients, and early childhood trauma (CT) may play a significant role in its development. The international PROMPT project investigates the…
View details →DOI: 10.1016/j.jad.2026.121859 Negative / Null Result ReportMedicine
Chen YC, Chang HJ, Chang CW et al. · 2026 · Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
Introduction Delirium is a common and serious complication in critically ill patients, associated with higher mortality, prolonged intensive care unit (ICU) stays, and cognitive impairments. Furthermore, renal dysfunction is a…
View details →DOI: 10.1097/wnp.0000000000001238 