A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21346 results · page 561 of 712
Bevilacqua C, Boscarato V, Pieroni G et al. · 2024 · Preprint
Background: developmental dysplasia of the hip (DDH) is a condition characterized by abnormal hip development in infancy. Early diagnosis allows for effective treatment, while late presentation often necessitates complex surgical…
Rajamanickam SK, Prades Morera E, Agarwal A et al. · 2025 · Cureus
Background Fine needle aspiration cytology (FNAC) is widely used to evaluate head and neck masses, with both ultrasound (US)-guided and freehand techniques being employed. While US-guided FNAC is thought to enhance accuracy, freehand FNAC…
Fortier A, Zouaoui I, Dumais A et al. · 2024 · Psychiatric services (Washington, D.C.)
Objective Recreational cannabis legalization (RCL) is expanding rapidly. RCL's effects on mental health issues are of particular concern because cannabis use is more frequent among people receiving psychiatric care and is associated with…
Rodrigo C, Gnanathasan A · 2024 · Transactions of the Royal Society of Tropical Medicine and Hygiene
Globally, snakebites cause an estimated 80 000-140 000 deaths annually. While there are evidence-based recommendations for managing snakebite victims, recommendations on the prevention of snakebites are limited to expert opinions. We…
Paisant A, Faroche E, Fouche A et al. · 2024 · Abdominal radiology (New York)
Purpose Preoperative imaging is now recommended in patients with suspected acute appendicitis (AA) by the World Society of Emergency Surgery. Our aims were (i) to describe our local practice and (ii) to evaluate the efficiency of…
Hinney B, Wiedermann S, Vaneev X et al. · 2024 · Parasites & vectors
The population of South American camelids (SAC) has been steadily growing in Europe, where they are confronted with the regional endoparasite population of ruminants. As there are no anthelmintic drugs registered for use against nematode…
Shen C, Zhu Z, Zhang X et al. · 2024 · Preprint
Purpose: Numerous epidemiological studies have explored the association between the components of metabolic syndrome (MetS) and risk of prostate cancer (PCa). However, to date, the findings have yielded inconclusive results. This study…
Mildner FO, Sykora MM, Hackl H et al. · 2024 · Lung cancer (Amsterdam, Netherlands)
Background Cancer immune evasion is critical in non-small cell lung cancer (NSCLC) and has been targeted by immunotherapy. High soluble (s)PD-L1 is associated with reduced survival and treatment failure in advanced stages. Here we…
Johnson MS, Adams VM, Byrne J · 2024 · Preprint
Abstract Effective adaptation to climate risks requires identifying and realizing community beliefs about which locations require management attention. Environmental planners and asset managers, especially those in rural and regional…
Le NT, Nguyen TG, Huynh NYN et al. · 2025 · Scientific reports
Dietary calcium's role in human health and disease prevention is inconclusive. We examined the associations between dietary calcium intake and the risk of overall and specific causes of mortality. A prospective cohort study was performed…
Manni G, Pambianco M, Sicuro C et al. · 2025 · International journal of molecular sciences
Hepatic actinomycosis (HA) and IgG4-related inflammatory pseudotumors are rare and often overlooked causes of liver mass, which can easily be misdiagnosed as primary liver cancer or metastasis. Diagnosis is arduous due to unspecified…
Borz-Baba L, Aydin A, Parvin R · 2026 · Cureus
Metabolic-associated steatotic liver disease (MASLD) is a common medical condition that can progress to metabolic-associated steatohepatitis (MASH) and advanced fibrosis, leading to severe outcomes. Liver biopsy continues to be the…
Sakuma K, Yoshimura K · 2026 · Journal of environmental radioactivity
Tritium ( 3 H) is the principal radionuclide remaining in ALPS-treated water discharged from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), and its potential environmental impact has drawn considerable attention. To evaluate possible…
Larson ME, Pan Y, Reidy L et al. · 2026 · PloS one
People with HIV (PWH) experience elevated cardiovascular disease risk compared to people without HIV. Stimulant use may further increase subclinical myocardial injury among PWH, but data on cardiovascular biomarkers, including serum…
Geamănu A, Pîrvulescu RA, Tricorache D et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: Hydroxychloroquine (HCQ) is widely used in systemic lupus erythematosus (SLE), yet cumulative exposure may result in progressive retinal toxicity. Structural biomarkers capable of identifying subclinical damage remain…
Sung K · 2026 · Environmental management
Trail penetration within strictly designated protected areas is often treated as a conservation concern, yet its consequences for vegetation trends at national scales remain empirically unresolved. This study evaluated whether trail…
Simonis L, Marcour Y, Embacher J et al. · 2026 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Assessment of hepatic steatosis is key for diagnosis and monitoring of steatotic liver disease. Controlled attenuation parameter is widely used, but concerns regarding its measurement variability exist. We evaluated the…
Ünlü C, Aksoy H · 2026 · BMC pregnancy and childbirth
Background Anti-D immunoglobulin administered in the early third trimester to Rhesus D negative women with Rhesus D incompatibility is widely assumed to provide protection against silent fetomaternal haemorrhage until delivery. However,…
Corn E, Becht K, Adefres B et al. · 2026 · Gynecologic oncology reports
Purpose Cervical cancer is the number one cause of cancer-related mortality for women in Botswana, where care is complicated by the country's severe shortage of gynecologic oncologists. Recent data suggests that "low-risk" stage I cervical…
Martinos N, Kroupis C, Gypari M et al. · 2026 · Current issues in molecular biology
Background/objectives Histologic mucosal healing is an increasingly recognized therapeutic target in inflammatory bowel disease (IBD), yet reliable non-invasive correlates remain limited. This study aimed to evaluate circulating cytokine…
Kim EJ, Kim SY, Kee YK et al. · 2026 · Preprint
Abstract Far-infrared (FIR) therapy has been proposed to improve vascular access flow (Qa) in patients receiving maintenance hemodialysis through an arteriovenous fistula (AVF) or arteriovenous graft (AVG). However, vascular access blood…
Han P, Chen P, Zhang L et al. · 2026 · Preprint
Abstract Background Small-incision lenticule extraction (SMILE) removes an intrastromal lenticule whose stiffness differs between corneal meridians, producing measurable stromal mechanical anisotropy. Whether this meridional anisotropy…
Walmsley SL, Nabipoor M, Qi F et al. · 2026 · Clinical & translational immunology
Objectives To assess neutralizing antibody responses to emerging SARS-CoV-2 variants. Methods We explored SARS-CoV-2 neutralizing antibodies in140 adults participating in a longitudinal study of antibody responses to COVID vaccines.…
Bermingham MD, Meredith RT, Mills H et al. · 2026 · Frontiers in allergy
Quantifying food allergens in complex matrices is hindered by thermal processing, particularly in baked products used for oral food challenges (OFCs), where limited data exists on effects on clinically relevant allergens. To address this,…
Kennedy J, Cooley SA, Roman Fox J et al. · 2026 · The Journal of infectious diseases
Background As persons with human immunodeficiency virus (PWH) live longer, interactions between human immunodeficiency virus (HIV), aging, and structural brain integrity become increasingly vital for understanding cognitive disorders. This…
Watrobska CM, Codd J, Portugal SJ et al. · 2026 · The Journal of experimental biology
The brain is energetically expensive. Therefore, energy availability may determine whether costly cognitive processes such as long-term memory can be expressed. However, there is a limited understanding of the metabolic costs associated…
Kuo MC, Younan SA, Williams PJ et al. · 2026 · Techniques in coloproctology
Background Robotic approach is increasingly being used for surgery in Crohn's disease. Robotic ileocolic resection (ICR) for Crohn's disease (CD) is comparable to laparoscopic ICR for short term outcomes; however, no studies have compared…
Flora RJ, Bullo J, Talaban J et al. · 2026 · Preprint
Abstract Organochlorine pesticides (OCPs) are persistent organic pollutants known for their environmental stability, hydrophobicity, and strong potential for bioaccumulation. Although many OCPs have been banned or restricted under…
Jankovič P, Chodzyński KJ, Vanrossomme AE et al. · 2026 · Neurology international
Background The risk stratification of unruptured intracranial aneurysms (UIAs) relies largely on static clinical and morphological parameters, which may not fully capture aneurysm-specific wall behavior. ECG-gated four-dimensional computed…
Kanack AJ, Mauch EE, Kohlhagen MC et al. · 2026 · Preprint
ABSTRACT Background Monoclonal gammopathy of thrombotic significance (MGTS) is a recently described chronic prothrombotic condition characterized by monoclonal anti-PF4 antibodies that are detected above the polyclonal antibody background…