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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21346 results · page 551 of 712

Negative / Null Result ReportOpen accessMedicine

Deficit irrigation and grafting effects on soil attributes, vegetative growth, yield components, and quality of 'Crimson Seedless' grapevines under a semiarid region.

Salama AM, Al-Obeed RS, Helmy A et al. · 2026 · Frontiers in plant science

This study evaluated the combined effects of grafting and deficit irrigation (DI) on soil attributes, vegetative growth, yield components, fruit quality, and water productivity of 'Crimson Seedless' grapevines under semiarid conditions. It…

View details →DOI: 10.3389/fpls.2026.1785340
Negative / Null Result ReportOpen accessMedicine

Fiber-to-stone distance and fragment size with holmium laser lithotripsy.

Glienke L, Hall TL, Ghani KR et al. · 2026 · Urolithiasis

Control of fragment size during laser lithotripsy has taken on increasing importance with adoption of ureteroscopic aspiration technologies. The objective of this study was to characterize the relationship between laser-fiber-to-stone…

View details →DOI: 10.1007/s00240-026-01970-x
Negative / Null Result ReportMedicine

Effect of ulnar positive variance on outcomes after arthroscopic transosseous repair of palmer 1B TFCC foveal tears.

Won JH, Shin JW, Kwon J et al. · 2026 · Journal of orthopaedic surgery and research

Purpose To determine whether ulnar positive variance (UPV) and relative ulnar positive variance (RUPV) affect clinical outcomes following arthroscopic transosseous repair of triangular fibrocartilage complex (TFCC) foveal tears. Methods…

View details →DOI: 10.1186/s13018-026-07010-z
Negative / Null Result ReportMedicine

Influence of surface treatment and cement type on the bond strength of additively manufactured permanent resin materials.

Diken Türksayar AA, Öztemel N, Yeşil Kurt İB et al. · 2026 · Odontology

This study evaluated the shear bond strength (SBS) of two dual-cure resin cements to a stereolithography-fabricated 3D-printed permanent crown material after various surface pretreatment protocols. Disc-shaped specimens were fabricated…

View details →DOI: 10.1007/s10266-026-01464-7
Negative / Null Result ReportMedicine

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study.

Ma Z, Luan H, Abulimiti K et al. · 2026 · BMC surgery

Objective To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal…

View details →DOI: 10.1186/s12893-026-03917-w
Negative / Null Result ReportMedicine

Correlation between swallowing and diaphragmatic functions in stroke patients with hemiplegia: a cross-sectional observational study.

Liu X, Zhao J, Wu Y et al. · 2026 · Scientific reports

Swallowing and diaphragmatic functions share neural regulatory pathways and require synchronous assessment. Patients who have had a stroke are susceptible to many complications, of which dysphagia and diaphragmatic dysfunction are…

View details →DOI: 10.1038/s41598-026-50341-4
Negative / Null Result ReportMedicine

The Effect of Preoperative Tranexamic Acid on Blood Transfusions in Geriatric Hip Fracture Surgery: A Randomized Controlled Trial.

Sullivan M, Perea LL, Bradburn E et al. · 2026 · Journal of orthopaedic trauma

Objectives To evaluate whether preoperative intravenous tranexamic acid (TXA) reduces postoperative blood transfusion rates in geriatric patients undergoing operative treatment for hip fracture. Methods Design Prospective, double-blinded,…

View details →DOI: 10.1097/bot.0000000000003172
Negative / Null Result ReportOpen accessMedicine

A comparative study of clinical efficacy, electrophysiological outcomes, and perioperative parameters between endoscopic carpal tunnel release and open carpal tunnel release for carpal tunnel syndrome.

Zhang Z, Liu Y, Yang H et al. · 2026 · Frontiers in cellular neuroscience

Purpose To compare the clinical efficacy of endoscopic (ECTR) and open (OCTR) carpal tunnel release for carpal tunnel syndrome (CTS) and provide evidence-based surgical guidance. Methods A retrospective cohort study was conducted including…

View details →DOI: 10.3389/fncel.2026.1845917
Negative / Null Result ReportOpen accessMedicine

Comparison of the Bond Strength of Silane-Treated Glass Fiber Posts at Different Solvent Evaporation Times: An In Vitro Study.

Ramos-Ramos V, Dextre-Herrera S, Ramírez-Vargas G et al. · 2026 · Journal of clinical and experimental dentistry

Background Silane is used as a coupling agent on glass fiber posts to enhance chemical interaction at the post-resin cement interface. This in vitro study evaluated the bond strength of silane-treated glass fiber posts at different solvent…

View details →DOI: 10.4317/jced.63939
Negative / Null Result ReportOpen accessMedicine

Association of central α-klotho with dopaminergic and melanocortin receptors on feed intake regulation in chicken.

Hassania Y, Hassanpour S, Zendehdel M et al. · 2026 · Poultry science

This study aimed to detemine association of central α-klotho with dopaminergic and melanocortin receptors on feed intake regulation in chicken. 264 meat-type chicken were included 6 experiments, each containing 4 groups. In experiment 1,…

View details →DOI: 10.1016/j.psj.2026.107042
Negative / Null Result ReportOpen accessMedicine

Association Between Early Childhood Caries and Systemic Inflammatory Profiles: A Retrospective Analysis of Children Undergoing Dental Treatment Under General Anesthesia.

Tez Yaşar BÇ, Çakmak AB, Eberliköse H et al. · 2026 · Children (Basel, Switzerland)

Background/objectives Early childhood caries (ECC) is a chronic inflammatory condition that may impose a systemic burden in pediatric patients. This study aimed to evaluate the association between dental caries severity, classified by dmft…

View details →DOI: 10.3390/children13050691
Negative / Null Result ReportMedicine

Impact of primary tumor SUVmax on PET accuracy in mediastinal lymph node staging of non-small cell lung cancer (NSCLC).

Kużdżał A, Gambuś K, Moszczyński K et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Positron emission tomography (PET) using 18-fluorodeoxyglucose (18-FDG) is the primary imaging modality for mediastinal staging of lung cancer. Higher standardized uptake value (SUVmax) reportedly correlates with more aggressive…

View details →DOI: 10.17219/acem/210368
Negative / Null Result ReportMedicine

Innovative competency-based education approach to radiology residency: integrating modular training in clinical practice and research.

Wan S, Ye L, Yang X et al. · 2026 · Insights into imaging

Objectives This study aimed to design and evaluate a competency-based education (CBE)-oriented modular training model for radiology residents, emphasizing interdisciplinary integration and disease-focused instruction to enhance clinical…

View details →DOI: 10.1186/s13244-026-02335-z
Negative / Null Result ReportMedicine

The Effect of Sleep Environment on Sleep Quality and Behavior in Firefighters: A Cross-Sectional Study.

Zera JN, Esper E, Simonson AP et al. · 2026 · International journal of environmental research and public health

Firefighters face high-stress occupational demands and irregular shift work that negatively impact sleep quality, which is intrinsically linked to long-term physical and psychological health. This cross-sectional study examines how the…

View details →DOI: 10.3390/ijerph23060692
Negative / Null Result ReportOpen accessMedicine

Tinnitus, temporomandibular disorders and muscle activity: what's the connection?

Çoban E, Altay B, Ulucan MÇ et al. · 2026 · Brazilian oral research

This study was aimed at comparatively evaluating the relationship between temporomandibular disorder (TMD) and subjective tinnitus, as well as the effects of TMD treatment on masticatory muscle activity, tinnitus symptoms, and patient…

View details →DOI: 10.1590/1807-3107bor-2026.vol40.037
Negative / Null Result Report

The Impact of Pregnant Women’s Dietary Behavior on the Physiological Adaptation Paradox and Maternal-Fetal Resource Conflict in Conflict Settings: A Predictive Analytical Study

Al-Wesabi MM, Eskander NA · 2026 · Preprint

This scientific study aims to assess the level of awareness, nutritional knowledge, and actual behavioral practices among pregnant women in the Capital District of Sana’a, Republic of Yemen, and to determine their impact on the health and…

View details →DOI: 10.64898/2026.06.17.26355845
Negative / Null Result ReportOpen accessMedicine

Effect of Powder-to-Liquid Ratio on pH, Calcium Ion Release, and Solubility Behaviors of Endodontic Bioceramics: An In Vitro Study.

Aka A, Matsuura T, Yoshimura A · 2026 · Journal of functional biomaterials

This study investigated the physicochemical properties of three endodontic bioceramics: MTA Flow White (F), MTA Repair HP (HP), and Nishika Canal Sealer BG multi (BG). Disc-shaped samples were immersed in deionized water for 28 days to…

View details →DOI: 10.3390/jfb17050220
Negative / Null Result ReportOpen accessMedicine

Association between changes in blood eosinophil levels and alterations in olfactory function in asthma.

Rhyou HI, Bae WY, Nam YH · 2026 · Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

Olfactory dysfunction has been observed in asthma, but its underlying mechanisms are poorly understood. This prospective study assessed olfactory function using the YSK Olfactory Function Test in 30 patients with moderate to severe asthma,…

View details →DOI: 10.1186/s13223-026-01025-1
Negative / Null Result ReportOpen accessMedicine

Comparative accuracy of complete-arch intraoral scans using full-scan and segmental-and-merge strategies.

Shin YJ, Lee KB, Kim SY et al. · 2026 · The journal of advanced prosthodontics

Purpose Full-arch intraoral scanning often suffers from cumulative stitching errors. Segmental scanning using overlapping segments followed by digital merging has been proposed as a potential solution, but quantitative evidence remains…

View details →DOI: 10.4047/jap.2026.18.2.116
Negative / Null Result ReportMedicine

Effect of common children's beverages on surface properties of single-shade and restorative material: an in vitro study.

Almutairi M, Mousa I, Alqahtani R et al. · 2026 · Scientific reports

Single-shade composite restorations can adapt to the tooth structure, improve esthetics, and reduce reliance on shade selection. The objective of this study was to assess the effect of four different children's beverages on the color…

View details →DOI: 10.1038/s41598-026-55540-7
Negative / Null Result ReportMedicine

Face-To-Face Vs. Online Behavioral Parent Training for Young Children with ADHD: Child and Parent Outcomes.

DuPaul GJ, Kern L, Dever BV et al. · 2026 · Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53

Objective Behavioral parent training is a first-line psychosocial intervention for young children with Attention-Deficit/Hyperactivity Disorder. Traditional face-to-face delivery is limited by access to therapists, feasibility, and/or…

View details →DOI: 10.1080/15374416.2026.2687069
Negative / Null Result ReportOpen accessMedicine

The rise and fall of glucocorticoids and immunosuppressants in idiopathic pulmonary fibrosis: a historical paradigm shift driven by mechanistic understanding.

Wen B, Wu X, Ma X et al. · 2026 · Frontiers in immunology

The therapeutic strategy for Idiopathic Pulmonary Fibrosis (IPF) has undergone a fundamental transformation over recent decades. Combination therapy with glucocorticoids and immunosuppressants, particularly the "triple therapy" regimen…

View details →DOI: 10.3389/fimmu.2026.1830573
Negative / Null Result ReportMedicine

[Colchicine in Cardiology Practice. Mechanisms of Influence on the Cardiovascular System, Use in the Treatment of Pericarditis and Ischemic Heart Disease].

Sukmarova ZN, Simonenko VB · 2025 · Kardiologiia

Despite significant advances in pharmacological, interventional, and surgical treatments for cardiovascular diseases (CVDs) in recent decades, it appeared that the effectiveness of standard treatments has reached a ceiling, and growing…

View details →DOI: 10.18087/cardio.2025.11.n3016
Negative / Null Result ReportMedicine

PD-L1 subpopulations of metastatic urothelial carcinoma demonstrate heterogeneity to chemotherapy: an integrated analysis of digitized trial results.

Zhou J, Jiang X, Liu Q et al. · 2026 · Cancer metastasis reviews

Efforts to translate advances in immunology into anti-cancer immunotherapies have progressed rapidly in recent years. Six antibodies acting on programmed death ligand 1 or programmed death 1 pathways were approved in 75 cancer indications…

View details →DOI: 10.1007/s10555-026-10314-5
Failed Experiment ReportMedicine

Efficacy of low dose colchicine on left ventricular hypertrophy in patients with coronary artery disease: A randomized controlled trial.

Chichareon P, Suwannanon R, Thungthienthong M et al. · 2026 · British journal of clinical pharmacology

Background Left ventricular hypertrophy (LVH) contributes to a substantial risk of adverse outcomes in patients with coronary artery disease (CAD). Inflammation is one of the mechanisms responsible for LVH progression. The study aimed to…

View details →DOI: 10.1002/bcp.70470
Failed Experiment ReportMedicine

ALSUntangled #82: N-acetylcysteine.

Yerraguntla S, Bakshi B, Chandran K et al. · 2026 · Amyotrophic lateral sclerosis & frontotemporal degeneration

N-acetylcysteine is a thiol-containing compound and a precursor of glutathione, with mechanistic plausibility for ALS, including reducing oxidative stress, regulating neuroinflammation, and mitigating mitochondrial dysfunction. Preclinical…

View details →DOI: 10.1080/21678421.2026.2638590
Negative / Null Result ReportMedicine

Optimal endoscopic treatment for rectal neuroendocrine tumors, confirmed after forceps biopsy: a Korean Association for the Study of Intestinal Diseases multicenter, randomized noninferiority trial.

Gweon TG, Kim SJ, Myung DS et al. · 2026 · Gastrointestinal endoscopy

Background and aims Insufficient submucosal lifting because of pretreatment with forceps biopsy frequently complicates endoscopic treatment of rectal neuroendocrine tumors (NETs) and potentially affects procedural outcomes. Despite…

View details →DOI: 10.1016/j.gie.2025.11.035