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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21339 results · page 535 of 712

Negative / Null Result ReportMedicine

Effect of age, sex, and BMI on serum olanzapine levels and their correlation with metabolic parameters and serum pro-inflammatory cytokine levels in schizophrenia patients.

Gao W, He X, Xu Y et al. · 2026 · BMC psychiatry

Objective Olanzapine is an atypical antipsychotic drug which is effective in the treatment of schizophrenia (SCZ). Olanzapine exhibits significant pharmacokinetic variability and is associated with a higher propensity for metabolic…

View details →DOI: 10.1186/s12888-026-08322-4
Negative / Null Result ReportMedicine

Reversed sound symbolism in speech sound disorders: Evidence for atypical cross-modal integration in a transparent language (Turkish).

Sözüçok BA, Sözüçok T, Seven I et al. · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior

This study examined sound-shape matching performance (the bouba-kiki effect) in Turkish-speaking children with speech sound disorders (SSD) and their typically developing (TD) peers. Participants included 60 children aged 51-71 months: 30…

View details →DOI: 10.1016/j.cortex.2026.05.002
Negative / Null Result Report

Clinical Predictors, Antibiogram, and the Relationship Between Abnormal Leucocytes and Positive Cerebrospinal Bacterial Isolates in Children seen at a Tertiary Facility in Nigeria.

Izuka O, Ogbonna I, Chidomere I et al. · 2026 · Preprint

Abstract Background: Acute bacterial meningitis (ABM) remains a significant public health concern in resource-limited settings like Nigeria. It is a frequent neurologic emergency among children and often presents at under-resourced medical…

View details →DOI: 10.21203/rs.3.rs-9116962/v1
Negative / Null Result ReportOpen accessMedicine

Assessment of PPD Conversion Rate in Patients Receiving Tumor Necrosis Factor-alpha Inhibitor Drugs.

Meidani M, Nasseri F, Rostamian A et al. · 2026 · Iranian journal of pathology

Background & objective Tumor necrosis factor-alpha (TNF-α) inhibitors are widely used in rheumatologic diseases but may increase the risk of primary tuberculosis (TB) infection or reactivation. Purified protein derivative (PPD) conversion…

View details →DOI: 10.22034/ijp.2026.2076748.3574
Negative / Null Result Report

Examining the domains of AI-assisted learning and their relationship with academic performance among nursing and allied health students: a cross-sectional study

Mualip N, Jeplin RG, Hashim J · 2026 · Preprint

Abstract Background: Artificial intelligence (AI) is increasingly integrated into health professions education, yet its impact on academic performance remains unclear. While previous studies have examined overall AI usage, limited research…

View details →DOI: 10.21203/rs.3.rs-9181082/v1
Negative / Null Result ReportOpen accessMedicine

The Association Between Height-Related Novel Anthropometric Indices and Cardiovascular Events: A Cross-Sectional Insight From the MASHAD Cohort Study.

Imannezhad M, Saberi-Karimian M, Darroudi S et al. · 2026 · Health science reports

Background and aims Cardiovascular diseases (CVDs) are a worldwide health concern, with factors like poor nutrition and environmental conditions contributing to the burden of CVD and its mortality. Height and other anthropometric indices…

View details →DOI: 10.1002/hsr2.71617
Negative / Null Result ReportMedicine

Determining jump and change of direction inter-limb asymmetries over pre-season in basketball players: An individualised approach.

Barrera-Domínguez FJ, Talpey S, Li F et al. · 2026 · Journal of sports sciences

Asymmetries are practical indicators of basketball players performance; however, longitudinal evidence remains limited. The aims of this study were to: (i) examine the variation of inter-limb asymmetry across three different time points…

View details →DOI: 10.1080/02640414.2026.2673238
Failed Experiment ReportMedicine

Investigation of the relationship between background parenchymal enhancement and breast cancer using 3.0 Tesla magnetic resonance imaging.

Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging

Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…

View details →DOI: 10.1016/j.clinimag.2025.110680
Negative / Null Result ReportMedicine

Orthorexia nervosa prevalence and associated factors in individuals attending a diet outpatient clinic: A cross-sectional study.

Atabay FE, Altin D · 2026 · Nutrition (Burbank, Los Angeles County, Calif.)

Background Orthorexia nervosa (ON) is characterized by an excessive preoccupation with consuming healthy foods, which may lead to dietary restrictions, psychological distress, and social isolation. Despite its increasing recognition, ON is…

View details →DOI: 10.1016/j.nut.2026.113258
Negative / Null Result ReportMedicine

The Effect of Time of Antimicrobial Administration on the Outcome of Septic Dogs.

Kidd A, Colee J, Perez-Rodriguez V et al. · 2025 · Journal of the American Animal Hospital Association

The objective of this study was to determine if the time to any antimicrobial administration, as well as time to appropriate antimicrobial administration, impacted hospitalization time of dogs diagnosed with sepsis. Records from 175 dogs…

View details →DOI: 10.5326/jaaha-ms-7473
Negative / Null Result ReportOpen accessMedicine

In relation to anxiety severity, puberty moderates functional connectivity between the amygdala and anterior cingulate cortex for negative relative to neutral stimuli during an emotional categorization task.

Suss SJ Jr, Kimbler A, Baker AE et al. · 2026 · Developmental cognitive neuroscience

Anxiety symptoms often escalate in peri-adolescence (ages 10-13 years), a sensitive period when puberty-related changes occur in neural systems implicated in psychopathology. Greater amygdala activation and altered functional connectivity…

View details →DOI: 10.1016/j.dcn.2026.101752
Negative / Null Result ReportOpen accessMedicine

Predicting treatment outcomes by door-to-device time and baseline characteristics in STEMI patients undergoing PPCI: a cross-sectional study in southern Iran.

Vosoughi S, Adineh M, Kardooni A et al. · 2026 · ARYA atherosclerosis

Background Primary percutaneous coronary intervention (PPCI) is considered the gold standard for ST-elevation myocardial infarction (STEMI) treatment. While door-to-device (DTD) time critically influences outcomes, its combined impact with…

View details →DOI: 10.48305/arya.2025.45242.3055
Negative / Null Result ReportOpen accessMedicine

A Retrospective Study of the Presentation, Imaging Findings, and Outcomes in 195 Patients with Maxillofacial Fractures Treated with Closed Reduction or Open Reduction with Internal Fixation.

Durmuş Hİ, Polat ME · 2025 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Maxillofacial fractures represent one of the most common forms of traumatic injuries, affecting both function and aesthetics, and are associated with significant morbidity and long-term sequelae. The incidence and distribution…

View details →DOI: 10.12659/msm.949933
Negative / Null Result ReportOpen accessMedicine

Clinical characteristics, medication use, and mortality outcomes in pediatric chronic kidney disease: A retrospective study at national hospital in Jakarta.

Eff ARY, Yuliana S, Afifah NN et al. · 2026 · Journal of advanced pharmaceutical technology & research

Chronic kidney disease (CKD) in children necessitates the use of a variety of drugs to reduce disease progression and manage complications. Polypharmacy is common in children with CKD, which can increase the occurrence of harmful drug…

View details →DOI: 10.4103/japtr.japtr_207_25
Negative / Null Result ReportMedicine

The relationship between patient activation measure and use of complementary and alternative medicine in oncology patients.

Falkenried J, Ahmadi E, Davitian K et al. · 2026 · Patient education and counseling

Background Complementary and alternative medicine (CAM) is increasingly utilized by cancer patients seeking additional ways to manage their health. Understanding how patient activation influences CAM usage and interest can guide more…

View details →DOI: 10.1016/j.pec.2026.109650
Negative / Null Result ReportMedicine

Shift work, stress, time management and occupational balance: Their associations with job satisfaction among female nurses.

Akyurek G, Gündoğmuş E, Ateş D · 2026 · Work (Reading, Mass.)

BackgroundShift work is a common requirement in healthcare settings to ensure 24-h continuity of care; however, it is associated with increased stress, disrupted circadian rhythms, and decreased job satisfaction among nurses. While…

View details →DOI: 10.1177/10519815261435984
Negative / Null Result ReportMedicine

Daily Associations Between Social Media Exposure and E-Cigarette Use Among Mexican American College Students.

Hébert ET, Bataineh BS, Marti CN et al. · 2026 · Substance use & misuse

Introduction Vaping-related content is prevalent on social media, including industry-sponsored advertising and user-generated content that normalizes use. While previous research suggests a link between social media exposure and vaping,…

View details →DOI: 10.1080/10826084.2026.2670609
Negative / Null Result ReportMedicine

Interpersonal Relationship, Academic Performance, & Life Skills: A Comparative Study of Children With and Without Emotional and Behavioral Problems.

Kheto P, Pallerla S, Bhattacharjee K et al. · 2026 · Clinical child psychology and psychiatry

BackgroundEmotional and behavioral problems (EBPs) in children significantly influence developmental domains, including interpersonal relationships, academic performance, and life skills.MethodsA cross-sectional study was adopted with…

View details →DOI: 10.1177/13591045261446331
Negative / Null Result ReportMedicine

Comparing Self-Reports, Pill Counts, and Electronic Devices in Assessing ART Adherence and its Association with Viral Suppression in Adolescents Living with HIV.

Kizito S, Ssewamala FM, Nabayinda J et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background We compared the performance of self-reports, pill counts, and electronic adherence measures in monitoring antiretroviral therapy (ART) adherence and association with viral suppression among adolescents living with HIV (ALHIV).…

View details →DOI: 10.1097/qai.0000000000003899
Negative / Null Result ReportMedicine

Timing and type of menopause are not risk factors for the onset of diabetes: a UK Biobank cohort study.

Quesada JA, Bertomeu-Gonzalez V, Cordero A et al. · 2026 · Menopause (New York, N.Y.)

Objectives Early and premature menopause are positively associated with coronary heart disease and stroke, but there is less evidence regarding its relationship with the onset of diabetes. The primary objective of this study is to assess…

View details →DOI: 10.1097/gme.0000000000002720
Negative / Null Result ReportMedicine

Vertical Maxillary Movement Is Associated With Incisal Display in Orthognathic Surgery.

Han MD, Shimchuk A, Dosoudil E et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Background Maxillary incisal display (MID) is a key feature in orthodontic and orthognathic surgical planning that critically impacts esthetics and forms the basis for the vertical positioning of the maxilla. In orthognathic surgical…

View details →DOI: 10.1016/j.joms.2026.04.023
Negative / Null Result Report

Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: A cross-sectional observational study

Tualeka AR, Aziz MY, Perumal V et al. · 2025 · Preprint

Background: Car painting workers are at risk of health problems, particularly kidney disorders, due to exposure to solvents containing benzene as the main ingredient in the car painting process. Therefore, the purpose of this study is to…

View details →DOI: 10.12688/f1000research.140287.3
Negative / Null Result ReportMedicine

Impact of emergency medical services volume on outcomes and management in prehospital traumatic cardiac arrest: a retrospective cohort study.

Morcel B, Yordanov Y, Mercier E et al. · 2026 · Scandinavian journal of trauma, resuscitation and emergency medicine

Background While volume-outcome relationships for non-traumatic out-of-hospital cardiac arrest have been reported in hospital settings, the impact of prehospital exposure, particularly for the rare and clinically complex entity of…

View details →DOI: 10.1186/s13049-026-01622-4
Failed Experiment Report

The Effect of Artificial Intelligence-Assisted Applications on the Perception of Nursing Values and the Mediating Role of Resilience

Cura ŞÜ, Atay S, Çimen M et al. · 2026 · Preprint

Abstract Background Artificial intelligence (AI)-assisted applications are becoming widespread in nursing practice and are creating a significant transformation in care processes. While this transformation may influence nurses’ perceptions…

View details →DOI: 10.21203/rs.3.rs-9039729/v1
Negative / Null Result ReportMedicine

Incidence and Associated Factors of ST-Segment Changes in Noncardiac Surgery Under General Anesthesia.

Gilani MT, Mafi N, Mashhadi L et al. · 2026 · Annals of cardiac anaesthesia

Background Intraoperative cardiac complications may result from an imbalance between myocardial oxygen supply and demand or from plaque rupture. Electrocardiographic (ECG) alterations in the ST-segment observed during surgery or anesthesia…

View details →DOI: 10.4103/aca.aca_243_25