A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19885 results in Negative / Null Result Report · page 534 of 663
Magura T, Mizser S, Horváth R et al. · 2026 · Insects
Urbanization is a major and rapidly expanding form of land-use change worldwide and is one of the main drivers of the decline in arthropod diversity. Within urban matrices, remnants of natural or semi-natural habitats serve as important…
Thorudottir S, Asgeirsson AG, Sigurdardottir HM · 2025 · Preprint
Visual mental imagery, or the ability to “see” with the mind’s eye, varies substantially across individuals. This vividness ranges from aphantasia, where no mental images are experienced, to hyperphantasia, characterized by exceptionally…
Frish Simcovich Y, Eigner E, Joskowicz L et al. · 2026 · The Journal of hand surgery, European volume
We examined the correlations between the surface morphology of acute scaphoid fractures and their stability. Our hypothesis was that a more irregular fracture surface would have a stabilizing effect on the fracture. A total of 75 isolated…
Li YC, Lemaire KK, Bruijn SM et al. · 2025 · Neuroscience
Walking without falling requires correcting the deviations of the centre of mass (CoM) trajectory relative to the base of support. This process is partially under feedback control. We investigated whether vestibular afference contributes…
Gautier R, Latinus M, Briend F · 2025 · Preprint
The Heartbeat Evoked Potential (HEP) is a potential marker of cardiac signal integration at the cerebral level, obtained by averaging epochs time-locked to the ECG R-peaks. The HEP is modulated across different experimental conditions with…
Spacey OG, Jones OR, Record S et al. · 2025 · Preprint
The population dynamics and life histories of macroparasites are fundamental to examine their impacts on hosts and ecosystems. Still, macroparasite population models often ignore parasite individual heterogeneity and are rarely applied to…
Brink KJ, Wiles TM, Stergiou N et al. · 2025 · Human movement science
The Optimal Movement Variability Hypothesis posits that healthy movements exhibit an optimal structure of variability, characterized by fractal patterns, which confer both stability and flexibility in motor control. This optimal,…
Weber RE, Schulze KM, Kenney NJ et al. · 2025 · American journal of cancer research
Breast cancer patients' maximal O 2 uptake (V̇O 2 max) values average 60-80% of age-predicted values which is often attributed to adjuvant therapy rather than risk factors, comorbidities, or the tumor and associated factors (e.g.,…
Chang DS, Littlepage-Saunders M, Hochstein MJ et al. · 2023 · Preprint
Convergent lines of evidence from animal models suggest that disrupted metabotropic glutamate receptor 2 (mGlu 2 ) function promotes high levels of drug consumption for a variety of psychoactive drugs including alcohol, opioids, and…
Erickson MG, Reinhardt LA, Svaren L et al. · 2024 · Journal of dairy science
Reducing dietary CP is a well-established means to improve N use efficiency. Yet, few studies have considered if transient restrictions in dietary CP could reduce the environmental footprint of late-lactation cows. We hypothesized that the…
Colomer-Poveda D, Mera-González I, Marcos-Frutos D et al. · 2026 · European journal of applied physiology
PURPOSE: The aim of this triple-blind, placebo-controlled study was to determine the effects of anodal transcranial direct current stimulation (a-tDCS) applied over the primary motor cortex (M1) and the dorsolateral prefrontal cortex…
Turan G, Spiertz V, Bein O et al. · 2023 · Preprint
The human brain is postulated to function as a prediction machine, constantly comparing incoming sensory input to predictions based on past experiences. When an event contradicts these predictions, it results in a prediction error (PE),…
Agir M, Sahin K, Pulatkan A et al. · 2026 · JSES international
Background Rotator cuff tears are a leading cause of shoulder pain, with high rerupture rates despite advancements in surgical techniques. Tendon-to-bone healing failure is often attributed to insufficient fibrocartilage regeneration at…
Meier K, van Hoeken D, Kager CCM et al. · 2025 · The International journal of eating disorders
Objective This study examined the impact of the COVID-19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre-pandemic (2015-2019) and in-pandemic (2020-2022) periods. We…
Haucke M, Heinz A, Heinzel S et al. · 2025 · European archives of psychiatry and clinical neuroscience
Adverse alcohol consumption is a major public health concern, which might have been further increased by the COVID-19 pandemic. In this study we investigated the impact of a lockdown stage on the association between alcohol consumption,…
Hascher K, Brown R, Janulis P et al. · 2026 · Biopsychosocial science and medicine
Objective Sexual minority (SM) populations experience worse cardiovascular health than heterosexual populations. One potential pathway is the effects of disclosure (sharing) or concealment (withholding) of SM identity due to anticipated…
Kweon J, Ganesh P, Brown JC · 2025 · Transcranial magnetic stimulation (2024)
Health and behavioral factors likely influence repetitive transcranial magnetic stimulation (rTMS) effectiveness, though clear support is lacking. Since habitual caffeine use has been found to impair corticomotor plasticity, we…
Chung YH, Williams LH, Brady TF et al. · 2025 · Journal of experimental psychology. General
Across many studies, verbal labels have been shown to significantly affect perceptual and cognitive processes. Here, we ask whether verbal labels can also improve visual working memory performance by making objects more recognizable. In a…
Popovic D, Reddy YNV, Omar M et al. · 2025 · Mayo Clinic proceedings
Objective Myeloperoxidase (MPO) is a heme peroxidase that scavenges nitric oxide and contributes to microvascular dysfunction. Patients with heart failure and preserved ejection fraction (HFpEF) have microvascular dysfunction that leads to…
Cohen M, Orgel E, Nevarez-Mejia J et al. · 2025 · EJHaem
Introduction Obesity contributes to poorer clinical outcomes in patients with acute lymphoblastic leukemia. We have shown that adipocytes cause anthracycline resistance by absorbing and metabolizing them into less-active alcohol…
Więcławski W, Smus A, Binder M · 2025 · Vision research
Pupillary light response (PLR) is modulated by the allocation of spatial attention. Larger pupil constrictions for bright stimuli presented on the left side are considered indicative of pseudoneglect, a subtle attentional bias observed in…
Mielniczek M, Lunde P, Grzyb W et al. · 2025 · Journal of functional morphology and kinesiology
Objective: The aim of the study was to investigate the effect of eight weeks of in-season training with wearable resistance attached to the forearm on spike velocity in female volleyball players. Methods: A total of 13 senior female…
Müller A, Zethof JHT, Pirani C et al. · 2025 · Rhizosphere
Biofilm formation on plant roots is traditionally assumed an important trait for plant growth promoting rhizobacteria, but its importance in the interplay between soil, plant roots and the rhizosphere bacterial and archaeal community is…
Sasaki AE, Benites NM, Rodrigues B et al. · 2025 · Hearing research
Rodent auditory brainstem neurons undergo substantial electrophysiological maturation during the postnatal period, spanning both pre- and post-hearing phases. These developmental adaptations support high-frequency, temporally precise…
Duong LHK, Lam NV, Tran VT · 2025 · Life (Basel, Switzerland)
Background: Atrial high-rate episodes (AHREs) detected by pacemakers are linked to increased stroke risk. The predictive value of high-sensitivity cardiac troponin I (hs-cTnI) for AHREs in pacemaker patients remains uncertain. This study…
Kim SH, Heo JH, Cunanan K et al. · 2026 · Journal of the Endocrine Society
Context While popular weight-loss medications have raised concerns about lean mass loss, the normative effects of nonpharmacologic weight loss on body composition remain unclear. Objective We assessed how the extent of weight loss from…
Parsowith EJ, Herring E, Cohen B et al. · 2025 · Experimental gerontology
Background Over 25% of U.S. older adults experience chronic knee pain, which worsens with inactivity, creating a cycle of pain, disability, and sedentary behavior. However, a limited understanding of the underlying mechanisms hinders the…
Rubino M, Fan R', Kulesz PA et al. · 2026 · The Laryngoscope
Objectives Complete or relative voice rest is recommended following phonomicrosurgery. Primarily, adherence to rest has been measured using patient reports, but their validity is unknown. Instrumental measures of rest adherence are…
Bertram AM, Lalot F, van der Werff L et al. · 2025 · Frontiers in psychology
Introduction Many daily situations require rapid judgments about whether information is true or false based on limited information. Prior research has predominantly examined how statement and source characteristics influence these…
Alharbi BM, Williams HE, Parr T et al. · 2025 · Mathematical biosciences
We propose a mathematical model based on coupled ordinary differential equations (ODEs) for metabolite concentrations with the aim of investigating how modifications to the rates affects outputs from a regulatory network. Our aim is to…