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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 534 of 676

Negative / Null Result ReportMedicine

Effects of vocal hygiene education program delivered via videoconference on acoustic and self-reported voice outcomes in Muslim religious officials in Turkiye.

Yesilli-Puzella G, Hanbal-İbooğlu E, Karataylı Özgürsoy S · 2026 · Scientific reports

This study examined the effects of a vocal hygiene education program delivered via videoconference on voice quality and self-perceived vocal outcomes among Muslim religious officials in Turkiye. The participants were 26 imams, aged between…

View details →DOI: 10.1038/s41598-026-54600-2
Negative / Null Result ReportMedicine

Acquired Buried Penis Reconstruction: A Description of the "Manta Ray" Technique and a Comparative Retrospective Cohort Analysis.

Massoud L, Jeng G, Parish C et al. · 2026 · Annals of plastic surgery

Adult acquired buried penis (AABP) is a condition in which the penis is obscured by excessive surrounding soft tissue or skin folds, commonly associated with obesity. It is often worsened by Balanitis Xerotica Obliterans or Lichen…

View details →DOI: 10.1097/sap.0000000000004780
Negative / Null Result ReportMedicine

Risk factors for postoperative deep vein thrombosis during hospitalization in patients with hip fractures: a prospective nested case-control study.

Chen Z, Wang X, Zhang J et al. · 2026 · Scientific reports

This study aimed to investigate the risk factors for postoperative deep vein thrombosis (DVT) in patients with hip fractures during hospitalization to establish a foundation for early prevention and management of DVT. We conducted a…

View details →DOI: 10.1038/s41598-026-55121-8
Negative / Null Result Report

HSP-70, Presepsin, and HO-1 for Differentiating Acute Appendicitis From Nonsurgical Abdominal Pain in Children: A Prospective Cohort Study

Sahin S, Ibrahimoglu H, Can F et al. · 2026 · Preprint

Abstract Background Diagnosing acute appendicitis in children remains challenging when symptoms, examination findings, laboratory results, or imaging are equivocal. Additional biomarkers may help support diagnostic decision-making in…

View details →DOI: 10.21203/rs.3.rs-9734817/v1
Negative / Null Result ReportMedicine

Progression-Free Survival with PARP Inhibitors According to Clinical Risk in Patients with Ovarian Cancer: An Indirect Comparison Using Reconstructed Data.

Gasperoni L, Del Bono L, Farolfi A et al. · 2026 · Oncology research

Background: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) are established maintenance treatments in ovarian cancer, but comparative efficacy across genetic profiles and relapse risk categories remains unclear. The aim of this…

View details →DOI: 10.32604/or.2026.077700
Negative / Null Result ReportMedicine

Gynecomastia: Etiological Analysis Beyond Hormonal Imbalance.

Kim JH, Song M, Lee K et al. · 2026 · Life (Basel, Switzerland)

Background: Gynecomastia is a benign enlargement of the male breast with multiple causes. This retrospective study evaluated whether serum estradiol (E2), testosterone (T), or the E2/T ratio differed between patients and controls, while…

View details →DOI: 10.3390/life16061010
Negative / Null Result ReportMedicine

Regional Fascial Plane Blocks and Early Postoperative Complications in Reduction Mammaplasty: A Retrospective Cohort Study.

Derebaşınlıoğlu H, Avcı O, Çelik M et al. · 2026 · Aesthetic plastic surgery

Background Regional fascial plane blocks are widely used in breast surgery for postoperative analgesia. While analgesic benefits are established, their impact on early complications after reduction mammaplasty remains unclear. Objective To…

View details →DOI: 10.1007/s00266-026-06068-8
Negative / Null Result Report

Maxillary Reconstruction in a Low to Middle Income Country: Institutional Experience Using Fibula Free Flap and Obturator Rehabilitation

Barakat KI, Zaki MH, Elnour MM · 2026 · Preprint

Introduction: Reconstruction of maxillary defects remains challenging because of the complex functional and aesthetic roles of the midface. Although both prosthetic obturation and microvascular reconstruction are established options,…

View details →DOI: 10.20944/preprints202606.0388.v1
Negative / Null Result ReportMedicine

Assessment of psychological and physiological responses to auditory and visual stimuli during recovery from acute stress induction.

Snyder EM, Son YJ, Li L et al. · 2026 · Physiology international

Workplace stress is one of the main sources of stress for adults, although physiological and cognitive factors may impact each person's stress response. Numerous studies have shown heart rate, heart rate variability, neural activity, and…

View details →DOI: 10.1556/2060.2026.00801
Negative / Null Result ReportMedicine

Impact of a multidisciplinary care pathway on follow-up and emergency department utilisation in paediatric musculoskeletal infections.

Bouchard M, Galán-Olleros M, Ng K et al. · 2026 · European journal of pediatrics

To evaluate whether implementation of a multidisciplinary care pathway was associated with changes in unplanned emergency department (ED) visits in children with musculoskeletal infections, and to assess its impact on readmissions,…

View details →DOI: 10.1007/s00431-026-06828-3
Negative / Null Result ReportMedicine

Key factors in the diagnosis of sesame allergy in children.

Hismiogullari A, Sancakli O, Ocak M et al. · 2026 · Allergy and asthma proceedings

Background: Sesame allergy (SA) is diagnostically challenging in childhood, and data on its natural course and clinical nonreactivity development are limited. Although oral food challenge (OFC) remains the diagnostic criterion standard,…

View details →DOI: 10.2500/aap.2026.47.260041
Negative / Null Result ReportMedicine

Comparison between drug-eluting bead transarterial chemoembolization versus conventional TACE in elderly patients with colorectal cancer liver metastases: a cohort study.

Tian L, Hu B, Song M et al. · 2026 · Frontiers in oncology

Background Drug-eluting bead (DEB) transarterial chemoembolization (TACE) possesses several advantages over conventional TACE (cTACE) such as higher intratumor drug concentration and lower systemic toxicity, which has been widely applied…

View details →DOI: 10.3389/fonc.2026.1785622
Negative / Null Result ReportMedicine

Lineage-specific selection signals in the Growth arrest-specific protein 8 (GAS8) domain protein of Trypanosoma melophagium.

Das A, Ghosh A, Pal S et al. · 2026 · Scientific reports

The Growth arrest-specific protein 8 (GAS8) domain-containing gene family (Orthogroup 6127at5690) is a highly conserved, single-copy orthologous group in the Trypanosoma taxa retained for codon-based evolutionary analysis (10 validated…

View details →DOI: 10.1038/s41598-026-56233-x
Negative / Null Result Report

HCC within LR-M on CEUS LI-RADS: Analysis of Washout Timing & Intensity

Samuel AS, Qiao A, Merrill CD et al. · 2026 · Preprint

Abstract Purpose: LR-M nodules > 1cm, are probably or definitely malignant, but not specific for hepatocellular carcinoma (HCC). HCC is found within LR-M category in 44%. We identify CEUS imaging features within the LR-M category…

View details →DOI: 10.21203/rs.3.rs-9596403/v1
Negative / Null Result ReportOpen accessMedicine

Thyroid Function Tests and Serum Amylase Levels in Chronic Kidney Disease: A Cross-Sectional Study Correlating Biochemical Changes With Disease Severity at a Tertiary Care Centre in India.

Sharma P, Samaria A, Tak H et al. · 2026 · Cureus

Background Chronic kidney disease (CKD) represents a major and growing health concern in both global and Indian populations. In addition to progressive renal dysfunction, CKD is frequently accompanied by metabolic and endocrine…

View details →DOI: 10.7759/cureus.104974
Negative / Null Result ReportMedicine

Association between body mass index and high grade cervical intraepithelial neoplasia (CIN 2/3) in a dysplasia referral population.

F G, J H, L SJ et al. · 2026 · Cancer treatment and research communications

Background Obesity is increasingly recognized as a risk factor for several malignancies, including cervical cancer. Women with obesity participate less frequently in screening and may have higher rates of unsatisfactory cytology,…

View details →DOI: 10.1016/j.ctarc.2026.101279
Negative / Null Result ReportMedicine

Aqueous Humor Angiotensin-Converting Enzyme and TGF-β1 Levels in Proliferative Vitreoretinopathy: A Prospective Clinical Study.

Koçak N, Özdemir A, Esenkaya M et al. · 2026 · Retina (Philadelphia, Pa.)

Purpose To evaluate plasma and aqueous humor angiotensin-converting enzyme (ACE) and transforming growth factor-β1 (TGFβ1) levels in patients with proliferative vitreoretinopathy (PVR) secondary to rhegmatogenous retinal detachment (RRD).…

View details →DOI: 10.1097/iae.0000000000004885
Negative / Null Result ReportMedicine

Cardiac Computed Tomography-Guided Procedural Planning for Percutaneous Mitral Paravalvular Leak Closure: Impact on Crossing Time.

Vella C, Romano V, Ricchetti G et al. · 2026 · The Canadian journal of cardiology

Mitral paravalvular leaks (PVLs) are a recognized complication of prosthetic valve implantation and may cause heart failure or hemolysis, often requiring percutaneous closure in patients at high surgical risk. Although transesophageal…

View details →DOI: 10.1016/j.cjca.2026.06.021
Negative / Null Result ReportMedicine

Skeletal muscle status and malnutrition as predictors of short-term radiotherapy response and oral mucositis in head and neck cancer.

Zhang H, Hu X, Zhao J et al. · 2026 · Precision radiation oncology

Objective This study aimed to investigate whether baseline skeletal muscle status and malnutrition in patients with locally advanced head and neck cancer (HNC) are associated with short-term treatment outcomes and acute radiation oral…

View details →DOI: 10.1002/pro6.70072
Negative / Null Result Report

Comparative Analysis of Lesion Detection and Uptake Characteristics of 68Ga-FAPI PET/CT versus 18F-FDG PET/CT in Gastric Cancer: A Preliminary Translational Study

KALENDER E, YILDIRIM EE, YERDEŞ E et al. · 2026 · Preprint

Abstract Purpose This study aimed to compare lesion detection and uptake characteristics of 68 Ga-FAPI PET/CT and 18 F-FDG PET/CT in patients undergoing imaging for gastric cancer (GC) staging. Methods A total of 24 patients with…

View details →DOI: 10.21203/rs.3.rs-9357738/v1
Negative / Null Result ReportMedicine

Clinical course after cardiac resynchronization therapy in transthyretin amyloid cardiomyopathy receiving disease-modifying therapy.

Yamauchi S, Kondo H, Mitarai K et al. · 2026 · Heart and vessels

Background The clinical course of patients with transthyretin amyloid cardiomyopathy (ATTR-CM) undergoing cardiac resynchronization therapy (CRT) remains insufficiently characterized, particularly in the era of disease-modifying therapy…

View details →DOI: 10.1007/s00380-026-02710-2