Negative / Null Result ReportMedicine
Weerts EM, Jenkins BW, Kuang RY et al. · 2024 · Pharmacology, biochemistry, and behavior
Cannabigerol (CBG) is a phytocannabinoid found in cannabis that is promoted for medical use and other health benefits, but current empirical data on the behavioral effects of CBG are lacking. The purpose of this study was to evaluate the…
View details →DOI: 10.1016/j.pbb.2024.173883 Negative / Null Result ReportOpen accessMedicine
Maier KS, Schiener T, Frigg A · 2025 · Journal of orthopaedic surgery and research
Background Short femoral stems were introduced for total hip arthroplasty (THA) to preserve bone stock, increase proximal load transfer, and enable minimal invasive approaches. However, after implanting the short curved Fitmore hip stem,…
View details →DOI: 10.1186/s13018-025-06064-9 Negative / Null Result ReportOpen accessMedicine
Comboni LM, Glover ES, Napolitano SC et al. · 2026 · Foods (Basel, Switzerland)
We assessed whether consuming UV light-exposed mushrooms (UVMs) would offset the seasonal decline in circulating total 25-hydroxyvitamin D (25OHD), an index of vitamin D status. During late fall and winter, 41 adults (19 M/22 F, age 43 ±…
View details →DOI: 10.3390/foods15091572 Negative / Null Result ReportMedicine
Tuffs C, Dupovac M, Richter K et al. · 2025 · The American journal of pathology
Liver fibrosis is characterized by excessive deposition of extracellular matrix due to chronic inflammation of the liver. Hepatic stellate cells (HSCs) become activated and produce increased amounts of extracellular matrix. Loss of…
View details →DOI: 10.1016/j.ajpath.2024.10.018 Negative / Null Result ReportOpen accessMedicine
Quan J, Kriebel M, Anunu R et al. · 2026 · Scientific reports
The Median Raphe (MR) provides a major, mainly serotonergic, input to the hippocampus, particularly influencing the dentate gyrus (DG), but its specific role remains unclear. Here, focusing on the dorsal DG, we investigated its…
View details →DOI: 10.1038/s41598-026-38004-w Negative / Null Result ReportOpen accessMedicine
Chia A, Burkill S, Ling Y et al. · 2026 · The British journal of ophthalmology
Aim To evaluate the effectiveness of atropine 0.01% in young premyopic and low-myopic children. Methods Children (5-9 years old) with premyopia (spherical equivalent refraction, SER+1.00 to -0.49D, n 156) or low myopia (SER -0.50 to…
View details →DOI: 10.1136/bjo-2025-328221 Negative / Null Result ReportMedicine
McDaniel AL, Gadoury DM, Moyer MM · 2024 · Crop Protection
Germicidal ultraviolet-C light (UV–C) has been used to effectively suppress grapevine powdery mildew (Erysiphe necator). However, effects on arthropod pests that would be simultaneously exposed to UV-C during applications directed at E.…
Negative / Null Result ReportOpen accessMedicine
Nilsson KH, Henning P, Lagerquist MK et al. · 2026 · Calcified tissue international
Osteoporosis is characterized by an imbalance in bone remodeling, resulting in bone loss and increased fracture risk. Inflammatory diseases, such as rheumatoid arthritis, are strongly associated with secondary osteoporosis due to…
View details →DOI: 10.1007/s00223-026-01481-2 Negative / Null Result ReportOpen accessMedicine
Leal R, Fragoso P, Venda J et al. · 2025 · Renal failure
Background The optimal immunosuppressive (IS) withdrawal strategy after kidney allograft failure remains unclear. This study evaluated the effects of prolonged calcineurin inhibitor (CNI) therapy on HLA sensitization, graft intolerance…
View details →DOI: 10.1080/0886022x.2025.2483386 Negative / Null Result ReportMedicine
Krikelis M, Gazi S, Trovas G et al. · 2024 · Joint bone spine
Introduction Denosumab (Dmab) is widely used for the treatment of post-menopausal osteoporosis. Its discontinuation is sometimes accompanied by multiple vertebral fractures. Romosozumab (Rmab) has not been tested for its ability to prevent…
View details →DOI: 10.1016/j.jbspin.2024.105754 Negative / Null Result ReportMedicine
Zhou AL, Ward RE · 2024 · Journal of dairy science
The focus of this work is the role milk polar lipids play in affecting gut permeability, systemic inflammation, and lipid metabolism during acute and chronic inflammation induced by a single subcutaneous injection of lipopolysaccharide.…
View details →DOI: 10.3168/jds.2024-24759 Negative / Null Result ReportOpen accessMedicine
Karp Z, Czarny J, Adamczewska-Wawrzynowicz K et al. · 2026 · Children (Basel, Switzerland)
Background : Infantile hepatic hemangiomas (IHH) are common benign vascular tumors in infancy with diverse presentations. Methods : We report a 7-week-old infant presenting with hepatosplenomegaly, multiple skin and hepatic hemangiomas,…
View details →DOI: 10.3390/children13040556 Negative / Null Result ReportOpen accessMedicine
Shunyakova J, Reynolds M, Taylor A et al. · 2025 · Frontiers in ophthalmology
Background Retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache (ROSAH) syndrome is an autosomal dominant disorder caused by a heterozygous missense mutation in alpha kinase 1 (ALPK1). This series reports the…
View details →DOI: 10.3389/fopht.2025.1535805 Negative / Null Result ReportMedicine
Frouin M, Cavalerie R, Piazza S et al. · 2024 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
A 2.5-year-old spayed female Chihuahua dog was presented with chronic cervical pain and exhibited a "prayer-like position" following a history of a 4-meter fall. CT and MRI revealed a moderate right-sided enlargement of the subdural space…
View details →DOI: 10.1111/vru.13362 Negative / Null Result ReportOpen accessMedicine
Le Corre E, Jousserand N, Maurey C et al. · 2026 · Journal of veterinary internal medicine
Background Subclinical bacteriuria (SBU) is frequently encountered in cats with chronic kidney disease (CKD), but it remains unclear if it is associated with survival and disease progression. Hypothesis/objectives To determine the…
View details →DOI: 10.1093/jvimsj/aalag064 Negative / Null Result ReportOpen accessMedicine
Villanova S, Gatti M, Colosio M et al. · 2026 · Nutrients
Background: Astragali radix is a traditional herb known for its antioxidant, anti-inflammatory, and immunomodulatory properties and has gained attention for its potential to support post-exercise recovery. However, the effects of long-term…
View details →DOI: 10.3390/nu18101598 Negative / Null Result Report
Chitolina R, Reis CG, Stahlhofer-Buss T et al. · 2023 · Preprint
Epilepsy is a prevalent neurological disorder, affecting approximately 1 to 2% of the global population. The hallmark of epilepsy is the occurrence of epileptic seizures, which are characterized by predictable behavioral changes reflecting…
View details →DOI: 10.1101/2023.07.13.548882 Negative / Null Result ReportOpen accessMedicine
Cao Y, Li Q, Guo W et al. · 2025 · Frontiers in immunology
To evaluate the efficacy of COVID-19 convalescent plasma (CCP) in preventing SARS-CoV-2 infection in hematopoietic stem cell transplantation (HSCT) recipients during the early post-transplant period, a single-center, randomized controlled…
View details →DOI: 10.3389/fimmu.2025.1626775 Negative / Null Result ReportMedicine
Lin S, Lytle KA, Fink N et al. · 2026 · Diabetes
Adipose tissue (AT) lipolysis insulin resistance results in excess free fatty acid (FFA) release. We tested the hypothesis that the ability of insulin to suppress AT lipolysis is unrelated to the ability of niacin to suppress lipolysis,…
View details →DOI: 10.2337/db25-0979 Negative / Null Result ReportOpen accessMedicine
Takemura A, Egawa T, Uemichi K et al. · 2025 · Biochemistry and biophysics reports
Mild hyperbaric oxygen (MHO) attenuates the muscle atrophy caused by muscle disuse. Training cessation results in the partial or complete loss of training-induced adaptations, including mitochondrial enzyme activities. The present study…
View details →DOI: 10.1016/j.bbrep.2025.102341 Negative / Null Result ReportOpen accessMedicine
van de Wetering R, Alder AF, Biggerstaff A et al. · 2025 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
The development of safer mu opioid receptor (MOR) agonists with reduced side effects is a key focus of pain research. Some studies have suggested that MOR agonists with reduced β-arrestin 2 (βArr2) signaling (i.e. G-protein biased…
View details →DOI: 10.1038/s41386-025-02214-z Negative / Null Result ReportOpen accessMedicine
Bearzi E, Sola S, Defferrari C et al. · 2026 · Dermatology reports
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin tumor, mainly linked to Merkel cell polyomavirus (MCPyV) and less often to ultraviolet exposure. Additional risk factors include advanced age and immunosuppression.…
View details →DOI: 10.4081/dr.2025.10457 Negative / Null Result ReportOpen accessMedicine
Stringari C, Stringari H, de Queiroz E Silva TF et al. · 2026 · Inflammopharmacology
INTRODUCTION: There is a marked overlap among the neuronal pathogenetic pathways involved in ulcer genesis and depression, and antidepressants can also exert a protective effect against gastric ulcers. OBJECTIVE: To summarize and…
View details →DOI: 10.1007/s10787-026-02240-3 Failed Experiment ReportMedicine
Carroll I, Schievink W · 2024 · Headache
Spontaneous intracranial hypotension (SIH) commonly results from ventral spinal cerebrospinal fluid (CSF) leaks and epidural patches are advocated as first-line treatment. Complications such as superficial siderosis can arise but have…
View details →DOI: 10.1111/head.14697 Negative / Null Result ReportOpen accessMedicine
Nocera FP, Fantini O, Abate G et al. · 2026 · Veterinary medicine and science
Background Traumatic and surgical wounds are common in cats, but their management is often challenging due to anatomical factors, delayed presentation, behavioural issues and frequent bacterial colonization. Objectives This prospective,…
View details →DOI: 10.1002/vms3.70929 Negative / Null Result ReportOpen accessMedicine
Orji C · 2025 · Cureus
Vericiguat is used as an adjunct therapy for patients with heart failure with reduced ejection fraction (HFrEF). Despite its availability in clinical practice, it remains underutilized among eligible patients. This case report describes…
View details →DOI: 10.7759/cureus.99626 Negative / Null Result ReportOpen accessMedicine
Hotz JF, Kaindl L, Krebs S et al. · 2026 · European journal of neurology
Introduction Hemiplegic migraine (HM) is a rare subtype of migraine with aura, characterized by transient, unilateral motor weakness. Due to its rarity, treatment strategies are lacking. Monoclonal antibodies targeting the calcitonin…
View details →DOI: 10.1111/ene.70514 Negative / Null Result ReportMedicine
Haddad S, Jacobs E, Núñez-Pereira S et al. · 2025 · Spine
Study design Retrospective analysis of a prospective multicenter adult spinal deformity (ASD) registry. Objective Assess whether spinal alignment deteriorates postsurgery in the absence of mechanical complications and evaluate the…
View details →DOI: 10.1097/brs.0000000000005142 Negative / Null Result ReportOpen accessMedicine
Wagstaff KM, Stein MS, Herschtal A et al. · 2025 · Pharmaceutics
Background: The efficacy of a single oral dose of Ivermectin as prophylaxis for SARS-CoV-2 is uncertain. This trial sought to evaluate the effectiveness of a single oral low dose of Ivermectin to prevent SARS-CoV-2 infection or reduce…
View details →DOI: 10.3390/pharmaceutics17091205 Negative / Null Result ReportMedicine
Çevik N, Hazar Bodrumlu E · 2024 · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
Objective Colour stability is important in the long-term aesthetic success of restorative materials and is affected by both internal and external factors. Internal discolourations are due to the properties of the restorative materials.…
View details →DOI: 10.1007/s40368-024-00894-7 