Negative / Null Result ReportMedicine
Silva LAS, Fernandes MS, Campos TMB et al. · 2026 · Journal of biomaterials applications
Calcium silicate cements (CaSiO 3 ) are widely used in bone repair treatments for both medical and dental applications. To meet the demands of tissue engineering, three calcium silicate cements were developed: a control group without…
View details →DOI: 10.1177/08853282251405355 Negative / Null Result ReportMedicine
Potten S, Li Z, Cohen E et al. · 2025 · Foot (Edinburgh, Scotland)
Introduction Calcaneal fractures present significant treatment challenges due to their complex anatomy and load-bearing function. Increasingly, minimally invasive techniques are used in treatment. This study evaluates the biomechanical…
View details →DOI: 10.1016/j.foot.2025.102205 Negative / Null Result ReportMedicine
Nuyen BA, Kruglik CP, Wang A et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective Patient satisfaction scores, especially the "likelihood to recommend" (LTR) a provider, are becoming increasingly important as measures of surgical quality. In this study, we examined the influence of a surgeon's vocal pitch and…
View details →DOI: 10.1002/ohn.70059 Negative / Null Result Report
Saravia DH, Silvan YA, Martinez JI · 2025 · Preprint
Abstract Despite similar rates of mental illness, non-Latinx Whites received care at higher rates compared to Latinxs (NIMH, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma compared to NLW, which can…
View details →DOI: 10.21203/rs.3.rs-7444634/v1 Negative / Null Result ReportMedicine
Kulbida M, Kemps E, Tiggemann M · 2026 · Appetite
Excessive soft drink and alcohol consumption have been associated with negative health outcomes. This study tested whether an intervention to reduce preferences for smaller, immediate rewards over larger, delayed rewards (i.e., delay…
View details →DOI: 10.1016/j.appet.2025.108296 Negative / Null Result ReportMedicine
Pauciulo C, Corda A, Tartari I et al. · 2026 · Journal of the American Veterinary Medical Association
Objective To describe the clinical outcomes of 10 cats diagnosed with CNS lymphoma treated with lomustine and corticosteroids. Animals Clinical records of privately owned cats diagnosed with CNS lymphoma and presented to a neurological…
View details →DOI: 10.2460/javma.25.07.0486 Negative / Null Result ReportOpen accessMedicine
Hille F, Theil JC, Gosheger G et al. · 2026 · Cancers
(1) Background : Megaprosthetic reconstruction of the knee is frequently required in limb salvage surgery for oncologic indications and in complex revision arthroplasty. The Modular Universal Tumor and Revision System (MUTARS) Total Knee…
View details →DOI: 10.3390/cancers18091408 Negative / Null Result ReportMedicine
Camacho-Martinez SV, Zai B, Hasani M et al. · 2025 · LWT.
The study aimed to optimize the performance of a gas phase hydroxyl radical process to inactivate Salmonella and Campylobacter jejuni associated with raw poultry meat. Chicken parts were inoculated with Salmonella or C. jejuni before…
Negative / Null Result ReportMedicine
Niyokuri AN, Nyalala SO, Mukamuhirwa A et al. · 2025 · Euphytica.
This study was conducted in situ to phenotypically characterise 28 accessions of calla lily (Zantedeschia spp.) sampled in 19 locations in Kenya and Rwanda. Ten plants per accession were sampled from each location for data collection on 15…
Negative / Null Result ReportMedicine
Stute P, Shapiro C M M, Morga A et al. · 2026 · Maturitas
Objectives Vasomotor symptoms (VMS) are a burden for women in menopause. Despite the availability of hormone therapy (HT), many cannot or do not wish to utilise it. The efficacy of the neurokinin receptor antagonists fezolinetant and…
View details →DOI: 10.1016/j.maturitas.2025.108782 Negative / Null Result ReportMedicine
Karabulut S, Topcu H, Er SN et al. · 2025 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Sleep problems are a hallmark of posttraumatic stress disorder (PTSD). Although the critical role of sleep for memory consolidation is well known, there is no consensus on the effect of sleep interruption or increased sleep duration…
View details →DOI: 10.1002/jdn.70066 Negative / Null Result ReportMedicine
Gómez DP, Nicolás VR, Marrero GC et al. · 2026 · American journal of physiology. Gastrointestinal and liver physiology
Hepatocyte nuclear factor 4 A (HNF4A) is a transcription factor that regulates a diverse range of intestinal epithelial genes involved in tissue renewal, differentiation, and metabolism, among other functions. The HNF4A locus is associated…
View details →DOI: 10.1152/ajpgi.00224.2025 Negative / Null Result ReportOpen accessMedicine
Martin E, Aigrot MS, Frère N et al. · 2025 · Multiple sclerosis journal - experimental, translational and clinical
Background To recover normal functions, remyelination in multiple sclerosis is crucial. Although endogenous remyelination occurs, it is often insufficient, and finding molecules promoting repair of demyelinated lesions is needed.…
View details →DOI: 10.1177/20552173251326913 Negative / Null Result ReportMedicine
Swami U, Jo Y, Narang A et al. · 2025 · European urology oncology
Although obesity has been associated with better overall survival (OS) among patients with metastatic castration-resistant prostate cancer, its association with OS has not been extensively explored in metastatic hormone-sensitive prostate…
View details →DOI: 10.1016/j.euo.2024.10.013 Negative / Null Result ReportOpen accessMedicine
D'Haens G, Danese S, Panaccione R et al. · 2025 · Journal of Crohn's & colitis
Background and aims Tyrosine kinase 2 is a downstream intracellular mediator of interleukin-23 signaling, which has a key role in the pathogenesis of inflammatory bowel disease. Deucravacitinib is a novel, oral, selective, allosteric…
View details →DOI: 10.1093/ecco-jcc/jjaf080 Negative / Null Result ReportMedicine
Clayton AH, Lasser R, Nandy I et al. · 2023 · The Journal of clinical psychiatry
Objective: To evaluate the efficacy and safety of zuranolone, an investigational neuroactive steroid and GABA A receptor positive allosteric modulator, in major depressive disorder (MDD). Methods: The phase 3, double-blind, randomized,…
View details →DOI: 10.4088/jcp.22m14445 Negative / Null Result ReportOpen accessMedicine
Fiorentù G, Bernardinello N, Giulianelli G et al. · 2025 · Advances in therapy
Pulmonary hypertension (PH) is a progressive syndrome characterized by increased pulmonary artery pressure. PH often complicates chronic lung diseases, thus contributing to a substantial disease burden and poor prognosis. The WHO Group 3…
View details →DOI: 10.1007/s12325-025-03129-3 Negative / Null Result ReportMedicine
Bodensohn R, Kaempfel AL, Boulesteix AL et al. · 2023 · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Background and purpose There is no randomized evidence comparing whole-brain radiotherapy (WBRT) and stereotactic radiosurgery (SRS) in the treatment of multiple brain metastases. This prospective nonrandomized controlled single arm trial…
View details →DOI: 10.1016/j.radonc.2023.109744 Negative / Null Result ReportOpen accessMedicine
Perez PN, Smesseim I, Sterman DH · 2026 · Immunotherapy
Lung cancer is the leading cause of cancer deaths, and despite therapeutic advances, recurrence and resistance persist. Local tumor ablation can function as an in situ vaccine, but thermal techniques may disrupt antigen and extracellular…
View details →DOI: 10.1080/1750743x.2026.2651072 Negative / Null Result ReportMedicine
Gondi V, Pugh SL, Mehta MP et al. · 2025 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial…
View details →DOI: 10.1200/jco-25-00221 Negative / Null Result ReportMedicine
de Lima Cruz GF, Pereira OG, Alves WS et al. · 2025 · Tropical animal health and production
Tropical grasses are widely used for silage, but their high fiber content and variable quality often limit ruminal degradation and animal performance. Strategies such as optimizing regrowth age (RA) and applying fibrolytic enzymes may help…
View details →DOI: 10.1007/s11250-025-04765-1 Negative / Null Result ReportOpen accessMedicine
Sadeghi M, Shahrooz S, Aghamohammadi M et al. · 2025 · BMC research notes
Objective Asthma is a common multifactorial inflammatory disease affecting both children and adults. Various cells and cytokines contribute to this inflammatory process. Smooth muscle contraction, vascular congestion, and airway edema lead…
View details →DOI: 10.1186/s13104-025-07455-1 Negative / Null Result ReportOpen accessMedicine
Pan X, Sarker S, Yu JJ et al. · 2026 · Insects
High rates of pest infestations are frequently reported in low-income homes in the U.S. However, even with access to effective insecticides, most residents are unaware of how to properly control indoor pests. We designed and evaluated the…
View details →DOI: 10.3390/insects17050483 Negative / Null Result ReportMedicine
Kass C, Katz-Greenberg G, Bodner J et al. · 2025 · Transplant immunology
Purpose Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The…
View details →DOI: 10.1016/j.trim.2025.102297 Negative / Null Result Report
Ferreira RD, Faleiros Ferreira CH, Gonçalves-Ferri WA · 2025 · Preprint
Background Inhaled nitric oxide (iNO) is a standard treatment for neonatal pulmonary hypertension in high-resource settings. Yet, its efficacy and cost-effectiveness in low- and middle-income countries (LMICs) remain underexplored. This…
View details →DOI: 10.1101/2025.08.19.25333602 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Pan J, Hou J et al. · 2025 · Medicine
Rationale Asthenozoospermia (AZS), a leading cause of male infertility, frequently results from genetic defects that disrupt flagellar assembly. Mutations in the DNAH11 gene can cause abnormal dynein arm structures, leading to AZS and…
View details →DOI: 10.1097/md.0000000000046556 Negative / Null Result ReportMedicine
Masri A, Tully TN, Como K et al. · 2025 · Journal of avian medicine and surgery
Euthanasia is a common veterinary medical procedure performed on terminally ill backyard chickens ( Gallus gallus domesticus ). To reduce stress for these animals, it is important to develop a euthanasia protocol that provides a rapid and…
View details →DOI: 10.1647/avianms-d-24-00022 Negative / Null Result ReportOpen accessMedicine
Lee JH, Hwang K, Jeong WK · 2026 · Clinics in orthopedic surgery
Background Arthroscopic rotator cuff repair is widely performed; yet tendon healing failure still occurs in some cases and remains a challenge. To address this issue, several studies have investigated intraoperative injection or patch…
View details →DOI: 10.4055/cios25235 Negative / Null Result ReportMedicine
Cuadrado C, Breedlove C, Toro H · 2025 · Avian diseases
Vaccination with a recombinant Newcastle disease virus (NDV) LaSota (LS) strain expressing Arkansas (Ark) -type infectious bronchitis virus (IBV) spike ectodomain (Se) protein and granulocyte-macrophage colony-stimulating factor (GMCSF)…
View details →DOI: 10.1637/aviandiseases-d-25-00035 Negative / Null Result ReportMedicine
Daudi S, Zampelis V, Belfrage O et al. · 2025 · The bone & joint journal
Aims Short, uncemented hip stems might provide a favourable alternative in total hip arthroplasty (THA) by preserving proximal bone mass through reduced strain-adaptive remodelling. We evaluated and compared the migration and…
View details →DOI: 10.1302/0301-620x.107b9.bjj-2024-1720.r1 