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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21733 results · page 510 of 725

Negative / Null Result ReportOpen accessMedicine

Effectiveness of physio-cognitive dual-task training on improving global cognition, health-related quality of life, and physical outcomes among older adults with neurocognitive disorders: an umbrella review.

Chern CWJ, Cheng LJ, Chiang GSW et al. · 2026 · Age and ageing

Background Physio-cognitive dual-task training (PCDT), combining physical and cognitive tasks, is a promising approach. However, clarity regarding its effectiveness and evidence credibility remains limited. Objective To evaluate PCDT…

View details →DOI: 10.1093/ageing/afag061
Negative / Null Result ReportOpen accessMedicine

Meta Analysis of DHA and EPA Supplementation on Cardiovascular Outcomes and Atrial Fibrillation Risk.

Shayan SK, Abbood RS, Al-Taie SF et al. · 2026 · Pharmacology research & perspectives

Cardiovascular diseases (CVD) remain to impose a main global burden of morbidity and mortality despite advances in anticipation and treatment. Omega-3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have…

View details →DOI: 10.1002/prp2.70265
Negative / Null Result ReportOpen accessMedicine

Medical students perceptions of spiritual care.

Prihanti GS, Firmansyah FH · 2026 · Frontiers in medicine

Introduction This study aimed to assess medical students' perceptions of spiritual care using a culturally adapted Muslim-context version of the Spirituality and Spiritual Care Rating Scale (SSCRS). Methods A cross-sectional study was…

View details →DOI: 10.3389/fmed.2026.1802023
Negative / Null Result ReportMedicine

The Mediating Role of Eudaimonic Well-Being in the Effect of Perceived Poverty on Quality of Life in the Elderly.

Aydin MA, Aydoğdu NG, Kizilarslan V et al. · 2026 · Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

Background This study was conducted to examine the mediating role of eudaimonic well-being in the effect of perceived poverty on quality of life in the elderly. Methods This descriptive cross-sectional study was conducted with 523 elderly…

View details →DOI: 10.1111/psyg.70178
Negative / Null Result ReportOpen accessMedicine

Arbuscular mycorrhizal symbiosis enhances the cadmium stress tolerance of Medicago sativa in association with regulation of the aminolevulinic acid pathway.

Li Y, Wang Z, Xu T et al. · 2026 · BMC plant biology

Arbuscular mycorrhizal (AM) fungi can effectively enhance the photosynthesis and antioxidant capacity of plants under cadmium stress; however, the underlying regulatory mechanisms remain poorly understood. This study focuses on the…

View details →DOI: 10.1186/s12870-026-08798-y
Negative / Null Result ReportOpen accessMedicine

Methane mitigation, nutritional evaluation, and in vitro degradation kinetics of diets based on tropical grass haylage treated with xylanase.

Duarte ABA, Dias-Silva TP, Viana WCC et al. · 2026 · Tropical animal health and production

The aim of this study was to evaluate the effect of xylanase addition (1.8 g/kg dry matter [DM]) to tropical grass haylage used in total mixed rations (TMR) on in vitro organic matter degradability, ruminal fermentation kinetics, and…

View details →DOI: 10.1007/s11250-026-05183-7
Negative / Null Result ReportMedicine

Engineering a synthetic niche for hADSC preconditioning with PRP, Lp-SN, and resveratrol nanoparticles.

Abbasi S, Akbari N, Yazdani M et al. · 2026 · Artificial cells, nanomedicine, and biotechnology

Ex vivo expansion of human adipose-derived stem cells (hADSCs) remains challenging because reduced-serum culture conditions can compromise short-term cell function. Here, we evaluated a microenvironment-inspired tri-component…

View details →DOI: 10.1080/21691401.2026.2691659
Negative / Null Result ReportMedicine

Temporal and suprathreshold central auditory skills in individuals with migraine: a comparative study based on clinical features.

Özkar B, Söylemez E · 2026 · Neurological research

Objective Previous studies evaluating central auditory processing in migraine have used conventional tests, but the findings have remained inconsistent. This study aimed to assess the central auditory abilities of individuals with migraine…

View details →DOI: 10.1080/01616412.2026.2620484
Failed Experiment ReportMedicine

Dissolved inorganic carbon driven dynamics of calcite shell formation in 12 strains of the freshwater algae Phacotus lenticularis (Chlorophyta).

Gruenert U, Benda J, Bossdorf O et al. · 2026 · PloS one

The present rise in temperature, pCO2 and altered precipitation impact lake water alkalinity and dissolved inorganic carbon (DIC) dynamics. Such changes on carbonate chemistry have been shown to modify calcification of shell-forming…

View details →DOI: 10.1371/journal.pone.0349771
Negative / Null Result ReportOpen accessMedicine

Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.

Tayebi SM, Mirzaei M, Stout JR · 2026 · Journal of the International Society of Sports Nutrition

Purpose High-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery. This randomized, double-blind, placebo-controlled pilot trial examined whether acute β -hydroxy- β -methylbutyrate free acid (HMB-FA)…

View details →DOI: 10.1080/15502783.2026.2665962
Negative / Null Result ReportOpen accessMedicine

CO<sub>2</sub>-Extract-Based Phytopreparation from <i>Arctium tomentosum</i> Mill. Root Exhibits No Acute and Subacute Toxicity and Suppresses Xylene-Induced Ear Edema and LPS-Induced Acute Inflammation in Mice.

Aitynova A, Dyusebaeva M, Issayeva D et al. · 2026 · Molecules (Basel, Switzerland)

A phytopreparation based on the CO 2 extract of Arctium tomentosum Mill. root (AT) was evaluated for its safety and anti-inflammatory potential in Swiss albino mice. Acute and 28-day subacute oral toxicity studies demonstrated that AT, at…

View details →DOI: 10.3390/molecules31111900
Negative / Null Result ReportMedicine

Parameter Specific Modulation of Neuronal Firing and Extracellular Action Potential Dynamics by Transcranial Focused Ultrasound Stimulation in Rat Motor Cortex.

Huang H, Smets C, Chen L et al. · 2026 · Brain stimulation

Background Transcranial focused ultrasound stimulation (TUS) has emerged as a promising tool for noninvasive neuromodulation. However, the specific effects of stimulation parameters on neural activity remain incompletely understood.…

View details →DOI: 10.1016/j.brs.2026.103145
Negative / Null Result ReportMedicine

Exploring the Association of Religion and Religiosity on Mammography Screening Among White and Black Women: Results from the Brazilian Longitudinal Study of Aging (Elsi-Brazil).

Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health

This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…

View details →DOI: 10.1007/s10943-026-02694-3
Negative / Null Result ReportMedicine

Effect of a 3.5 mm Tibial Plateau Leveling Osteotomy Locking Compression Plate on Serial Postoperative Tibial Plateau Angle Maintenance, Short-Term Osteotomy Healing, and Complication Rates in 45 to 70 kg Dogs.

Acuña J, Barnhart MD, Kennedy SC et al. · 2026 · Veterinary and comparative orthopaedics and traumatology : V.C.O.T

To evaluate the effect of a 3.5 mm tibial plateau leveling osteotomy (TPLO) locking compression plate on serial postoperative tibial plateau angle (TPA) maintenance, short-term osteotomy healing, and complication rates in dogs weighing 45…

View details →DOI: 10.1055/a-2865-3650
Negative / Null Result ReportOpen accessMedicine

Cardiac response to chronic restraint stress involves mineralocorticoid receptors in male Sprague-Dawley rats.

Sztechman D, Zera T, Czarzasta K et al. · 2025 · Physiological reports

In the present study, we aimed at elucidating whether exposure to chronic stress affects the expression of cardiac mineralocorticoid receptors (MRs), whether it influences cardiac structure and function, and whether MRs blockade attenuates…

View details →DOI: 10.14814/phy2.70549
Negative / Null Result Report

Innovation and Productivity as Engines of Economic Growth in Ghana

Xuhua H, Bakpa EK, Yeboah JA · 2026 · Preprint

This paper examines the dynamic relationship between innovation, total factor productivity (TFP), and economic growth in Ghana using annual data for the period 1965–2021. Although Ghana has recorded relatively strong economic growth,…

View details →DOI: 10.20944/preprints202604.1738.v1