Negative / Null Result ReportOpen accessMedicine
Steensbæk MT, Yousef S, Bahuet AR et al. · 2026 · Acta anaesthesiologica Scandinavica
Background Closed reduction of distal radius fractures is painful, and current analgesic strategies may be inadequate. Ultrasound-guided lateral infraclavicular brachial plexus block may offer complete analgesia and muscle relaxation,…
View details →DOI: 10.1111/aas.70246 Negative / Null Result ReportOpen accessMedicine
Santiago MDS, Wu GY · 2026 · Journal of clinical and translational hepatology
Alpha-1 antitrypsin deficiency (AATD) is an autosomal codominant genetic disorder caused by mutations in the SERPINA1 gene. It results in reduced circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor (PI) primarily…
View details →DOI: 10.14218/jcth.2026.00043 Negative / Null Result ReportOpen accessMedicine
Nawrocki PS, Rau BT · 2025 · Cureus
This report describes a case of hypokalemia-induced hemiplegia and altered mental status masquerading as an acute large vessel occlusion (LVO) stroke, and provides a brief discussion of stroke mimics. An air ambulance was dispatched to…
View details →DOI: 10.7759/cureus.94179 Negative / Null Result ReportMedicine
Wincewicz D · 2025 · Brain research
Pinpointing the bidirectional relationship between psychiatric and cardiovascular disorders holds the potential to tailor therapy and apply concepts of personalized treatment. Recent findings from both basic and clinical studies indicate…
View details →DOI: 10.1016/j.brainres.2025.149741 Negative / Null Result Report
Whitman T, Woolet J, Sikora MC et al. · 2025 · Preprint
Wildfires are natural disturbances characteristic of boreal forests. However, fire regimes around the world are changing, with effects on fire frequency and fire severity. Here, we present data from one and five years post-fire across 40…
View details →DOI: 10.1101/2025.03.29.646032 Negative / Null Result ReportOpen accessMedicine
Temürkol R, Güler H, Kaya A et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: The estimation of the postmortem interval (PMI) remains a complex challenge in forensic medicine. While macroscopic, biochemical, and molecular methods are well-documented, postmortem functional approaches at the organ level…
View details →DOI: 10.3390/diagnostics16091266 Negative / Null Result Report
Flores-Andrade XA, Peralta-Prado AB, Porras-Rosales E et al. · 2025 · Preprint
Abstract Background: The mycobacterial and cytomegalovirus co-infection represents a critical intersection of infectious challenges, especially in the context of people living with human immunodeficiency virus infection. This relation…
View details →DOI: 10.21203/rs.3.rs-6405843/v1 Negative / Null Result ReportOpen accessMedicine
ELghareeb A, Dawaba M, Eldeeb M et al. · 2026 · International braz j urol : official journal of the Brazilian Society of Urology
Introduction Concomitant bladder neck incision (BNI) with posterior urethral valve ablation (VA) was proposed to mitigate the long-term sequela of posterior urethral valve (PUV) and reduce the reoperation rates. This study aimed to…
View details →DOI: 10.1590/s1677-5538.ibju.2025.0539 Negative / Null Result ReportMedicine
Schieda N, Morash C, Lavallee LT et al. · 2025 · BJU international
Objective To compare clinically significant prostate cancer (CS-PCa) detection by transperineal (TP) compared to transrectal (TR) magnetic resonance imaging (MRI)-ultrasonography (US) fusion prostate biopsy. Patients and methods Males with…
View details →DOI: 10.1111/bju.16831 Negative / Null Result ReportOpen accessMedicine
Diop S, Aparicio M, Mounier R et al. · 2026 · Journal of intensive care
Background Correction of "metabolic acidosis" by sodium bicarbonate is a common practice in intensive care unit or operating room. The physiological rationale underlying its use relies on the potential harmful hemodynamics effects of…
View details →DOI: 10.1186/s40560-026-00870-x Negative / Null Result ReportMedicine
Majumdar KS, Abhinav T, Panuganti A et al. · 2025 · JCO global oncology
Purpose The literature suggests that elective neck dissection (END) may be avoided in primaries with a depth of invasion (DOI) Materials and methods In this retrospective institutional chart review, pathologic N classification (pN) was…
View details →DOI: 10.1200/go-24-00451 Negative / Null Result ReportMedicine
Mercier C, Billiet C, Ost P et al. · 2025 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose To test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8…
View details →DOI: 10.1200/jco-24-01447 Negative / Null Result ReportOpen accessMedicine
Paavonen J, Brunham RC · 2024 · Frontiers in cellular and infection microbiology
Localized provoked vulvodynia (LPV), also called vulvar vestibulitis or provoked vestibulodynia, is a major cause of dyspareunia that severely impacts sexual health. At the tissue level, lymphocytic inflammation and hyperinnervation are…
View details →DOI: 10.3389/fcimb.2024.1505845 Negative / Null Result ReportMedicine
Le Pallec C, Cerasuolo D, Cauvin JC et al. · 2025 · European journal of pediatrics
The respiratory rate-oxygenation index (ROXi) has been shown to be a reliable tool for predicting the risk of high-flow nasal cannula (HFNC) failure in adult patients with lower respiratory tract infections. However, the usefulness of the…
View details →DOI: 10.1007/s00431-025-06206-5 Negative / Null Result ReportOpen accessMedicine
Linz MS, Wang T, Friberg J et al. · 2026 · Trauma case reports
Introduction Traumatic hemipelvectomy is a rare operation, often performed for injuries caused by a high force mechanism such as a traffic or industrial accident, and often fatal. Most often performed emergently, here we report a traumatic…
View details →DOI: 10.1016/j.tcr.2026.101394 Negative / Null Result ReportMedicine
Wu TC, Lin CC · 2025 · Cancer prevention research (Philadelphia, Pa.)
The study by Downs and colleagues targets patients with non-muscle-invasive bladder cancer (NMIBC) to explore secondary/tertiary cancer prevention strategies. Utilizing a "window-of-opportunity" design, erlotinib was evaluated for its…
View details →DOI: 10.1158/1940-6207.capr-24-0491 Negative / Null Result ReportMedicine
Moon RE, Mitchell SJ · 2025 · Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
Gas can enter arteries (arterial gas embolism) due to alveolar-capillary disruption (caused by pulmonary overpressurization, e.g. breath-hold ascent by divers), veins (venous gas embolism, VGE) as a result of tissue bubble formation due to…
View details →DOI: 10.22462/10.12.2019.13 Negative / Null Result ReportOpen accessMedicine
Yalcin Y, Yalcin SE, Demir BC et al. · 2026 · BMC surgery
OBJECTIVE: The therapeutic role of lymphadenectomy in endometrial cancer remains controversial. Although systematic pelvic and para-aortic lymphadenectomy (PPLND) has been suggested to improve survival in certain patients, randomized…
View details →DOI: 10.1186/s12893-026-03640-6 Negative / Null Result ReportMedicine
Regidor E, Dionigi C, Ghoraishi M et al. · 2026 · Journal of periodontal research
Aims To evaluate the adjunctive effect of enamel matrix derivative (EMD) in the reconstructive surgical therapy of peri-implantitis. Methods Forty subjects (44 implants) affected by peri-implantitis (PPD ≥ 5 mm, positive BOP/SOP,…
View details →DOI: 10.1111/jre.13396 Negative / Null Result ReportOpen accessMedicine
Liu Z, Cong X, Liu Z et al. · 2026 · Frontiers in immunology
Renal cell carcinoma (RCC) has historically posed a significant therapeutic challenge in the adjuvant setting. Although surgical resection remains the cornerstone of curative-intent treatment for localized disease, a substantial proportion…
View details →DOI: 10.3389/fimmu.2026.1816253 Negative / Null Result ReportMedicine
Marchetti M, Pinzi V, Gemma M et al. · 2025 · International journal of radiation oncology, biology, physics
Purpose During the last decades, in addition to tumor control, hearing preservation has become an important priority in the treatment of vestibular schwannoma (VS). Given that the potential advantages of hypofractionated radiosurgery (hRS)…
View details →DOI: 10.1016/j.ijrobp.2025.03.081 Negative / Null Result ReportOpen accessMedicine
Xu J, Wang H, Chen J et al. · 2025 · International journal of surgery (London, England)
Background Autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis and osteoarthritis, are debilitating conditions with limited curative options. Stem cell therapy offers promising regenerative and immunomodulatory benefits.…
View details →DOI: 10.1097/js9.0000000000003130 Negative / Null Result ReportMedicine
Harris LR, Jörges B, Bury N et al. · 2025 · Experimental brain research
Under the microgravity of the International Space Station, many of the normal processes that determine the perceptual upright on Earth are disrupted. For example, somatosensory cues are absent and an applied physical linear acceleration…
View details →DOI: 10.1007/s00221-025-07023-w Negative / Null Result ReportOpen accessMedicine
Faghihian R, Tofighi MM, Ziaei S et al. · 2025 · European oral research
Purpose A way to reduce the pain of injection is applying of external cold or vibrations with BUZZY, along with spinal cord gate control systems. We aimed to evaluate the effectiveness of this method in reducing children's pain and anxiety…
View details →DOI: 10.26650/eor.20241409206 Negative / Null Result ReportOpen accessMedicine
Costa TE, Lauar JC, Innecchi MLR et al. · 2026 · Journal of the Endocrine Society
Introduction New evidence has emerged linking uric acid levels to Chronic Kidney Disease and Mineral and Bone Disorder (CKD-MBD). However, interventional studies remain scarce. We evaluated the effect of allopurinol on CKD-MBD biomarkers.…
View details →DOI: 10.1210/jendso/bvag118 Negative / Null Result ReportOpen accessMedicine
Ru X, Wu L, Guo Y et al. · 2025 · Medicine
Given that homocysteine (Hey) may be a viable target for intervention and that there is uncertainty regarding the causal relationship between plasma Hcy levels and colorectal cancer (CRC), this study used Mendelian randomization (MR) to…
View details →DOI: 10.1097/md.0000000000045773 Negative / Null Result ReportMedicine
Crespo R, Poudel I, Malheiros DM et al. · 2024 · Journal of Applied Poultry Research.
This study aimed to compare the performance of 2 quantitative ultrasound (QUS) devices and to investigate the possible relationship between bone density, measured by speed of sound (SOS), and the biomechanical properties of bone. The bone…
Negative / Null Result ReportOpen accessMedicine
Aziz YN, Aragon Garcia R, Plummer P et al. · 2026 · Stroke (Hoboken, N.J.)
Background Recent randomized trials showed no benefit of mechanical thrombectomy (MT) for ischemic stroke due to distal medium vessel occlusion (DMVO). We sought to understand the use of MT for DMVO stroke treatment before and after the…
View details →DOI: 10.1161/svin.125.001965 Negative / Null Result ReportOpen accessMedicine
Niazi SK · 2024 · International journal of molecular sciences
Although decades of intensive drug discovery efforts to treat neurodegenerative disorders (NDs) have failed, around half a million patients in more than 2000 studies continue being tested, costing over USD 100 billion, despite the…
View details →DOI: 10.3390/ijms251810211 Negative / Null Result ReportOpen accessMedicine
Nutbeam T · 2026 · Scandinavian journal of trauma, resuscitation and emergency medicine
Background Cervical collar application remains prevalent in trauma care despite the absence of evidence of neurological benefit from spinal immobilisation. Clinical behaviour in this area has proven resistant to change, and the persistence…
View details →DOI: 10.1186/s13049-026-01600-w 