Negative / Null Result ReportOpen accessPlant culture
J. Harb, A. A. Saquet, R. Bisharat et al. · 2012 · Journal of Applied Botany and Food Quality
Biochemical and quality changes of sweet cherries cv. Regina were assessed over three consecutive years after storage in different modified atmosphere packaging (MAP) liners, with or without hydrocooling, compared to regular atmosphere (RA) storage. All plastic liners used in the experiment resulted in CO2-enrichment and O2-reduction inside packages, with the following impact on fruit quality after five weeks of storage: improved retention of fruit firmness and red color of skin, no significant effect on acidity and total soluble solids, and minimal loss of fruit weight. Fruit decay was absent
Negative / Null Result ReportOpen accessAgriculture
Ondřej Sedlář, Jiří Balík, Jindřich Černý et al. · 2025 · Agronomy
Humic substances affect both soil fertility and carbon sequestration. This study aimed to evaluate the effect of straw return on the quality of soil organic matter on arable land commonly farmed by private farmers at 65 different sites between 2012 and 2022 in the Czech Republic (central Europe). In this study, most of the carbon supply was applied in straw (67% of the carbon input on average). No significant correlation between the total carbon input and both parameters of soil organic matter quality and soil organic carbon content was found. The ratio of optical absorbance at 465 to 665 nm (
View details →DOI: 10.3390/agronomy15061277 Negative / Null Result ReportOpen accessPsychology
Thomas DiBlasi, Courtney Pisano, Kaleigh Keenan et al. · 2024 · International Journal of Personality Psychology
This research comprises of two studies examining the effect of impossible problem solving on state anger. For the first study, using 155 participants on Amazon’s MTurk, a significant difference was observed on state anger from baseline to post-intervention (p = .04). Due to the well documented concerns about using MTurk participants, a second study involving 111 participants from a small liberal arts college was conducted. Using the same design, no significant effect of time on state anger was observed (p > .05). Post-hoc analyses indicated a significant difference between MTurk and in-person
View details →DOI: 10.21827/ijpp.10.41840 Negative / Null Result ReportOpen accessChemical technology
Yun-a Kim, Sanghun Park, Yunhwan Park et al. · 2022 · Foods
This study aimed to determine whether fermented soy sauce has a mutually synergistic effect on the quality and storage properties of pork patties, and to investigate the effects on the availability and physicochemical properties of various taste ingredients of soy sauce, a traditional Korean food ingredient. The experimental groups were as follows: Control (−): No additives; Control (+): 0.1% ascorbic acid; T1: 1% fermented soy sauce; T2: 3% fermented soy sauce; T3: 5% fermented soy sauce. No significant difference was detected in moisture, protein, and fat among the various treatment groups;
View details →DOI: 10.3390/foods11071004 Negative / Null Result ReportOpen accessMicrobiology
Nuiyen Aussanee, Khumin Vinta, Wichai Siriwan · 2025 · BIO Web of Conferences
Cadmium contamination found in paddy fields in the Maesot District of Tak Province, Thailand. This area was remediated using 50mg/L of ZVI. The study aimed to isolate and identify soil bacteria in the soil and rice roots and to investigate ZVI’s effect on the isolated bacterial cells. The results indicated no significant difference in soil bacteria content before and after remediation at the 95% confidence level. Twelve isolates of nitrogen-fixing bacteria were obtained. Those isolates could grow at high concentrations of 300 mg/L of ZVI. RH17 had a high tolerance for TSA with 300 mg/L of ZVI
View details →DOI: 10.1051/bioconf/202516403001 Negative / Null Result ReportOpen accessFood processing and manufacture
ZHANG Ning, YU Shilan, YAN Haoyi, ZHANG Yunjun, HAN Xiaoyu, REN Hongyu, CHEN Yuqing, LING Tiejun, AN Maoqiang · 2024 · Shipin Kexue
This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick tea and to identify the metabolites from fungi in Fuzhuan brick tea. Metabolomic studies on fresh tea leaf samples, Hunan and Shaanxi Fuzhuan brick teas and fungi from them were performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and molecular networks of characteristic metabolites. The results showed no significant difference between Hunan and
View details →DOI: 10.7506/spkx1002-6630-20231108-066 Negative / Null Result ReportOpen accessSurgery
Tsuyoshi Sakuma, Toshiaki Kotani, Tsutomu Akazawa et al. · 2021 · Spine Surgery and Related Research
Introduction: Proximal junctional kyphosis (PJK) is an acute complication of adult spinal deformity (ASD) surgery and may require re-operation because of proximal junctional failure (PJF). PJK causes and prevention strategies remain unknown. This study aimed to investigate the differences in the backgrounds of patients with PJK, compared to those without PJK, in ASD surgery. Methods: We included data from 86 patients who underwent ASD surgery between 2012 and 2018. There were 40 patients (46.5%) with PJK; 46 patients did not have PJK until the last follow-up. We evaluated patient demographics,
View details →DOI: 10.22603/ssrr.2020-0093 Negative / Null Result ReportOpen accessBiology (General)
Xinglin Zhang, Jie Ren, Na Li, Wenjuan Liu, Qingmin Wu · 2009 · International Journal of Biological Sciences
Brucella melitensis is a facultative intracellular pathogen. An operon composed of BMEI0066, which encodes a two-component response regulator CenR, and BMEI0067, which encodes a cAMP-dependent protein kinase regulatory subunit, has been predicted to exist in many bacterial species. However, little is known about the function of this operon. In order to characterize this operon and assess its role in virulence, we constructed a marked deletion mutant of BMEI0066. The mutant was less able to withstand hyperosmotic conditions than wild-type (16M), but showed no significant difference with 16M whe
Negative / Null Result ReportOpen accessInternal medicine
Woo Yeong Park, Yoon Kyung Chang, Young Soo Kim et al. · 2021 · Kidney Research and Clinical Practice
Background This study evaluated the impact of acute kidney injury (AKI) on posttransplant clinical outcomes for deceased donor (DD) kidney transplantation (KT) using the Kidney Donor Profile Index (KDPI) system. Methods Overall, 657 kidney transplant recipients (KTRs) receiving kidneys from 526 DDs from four transplant centers were included. We divided them into the high and low KDPI donor groups by 65%, the KDPI score, and both groups were subdivided into the AKI-DDKT and non-AKI-DDKT subgroups according to AKI in DDs. Results There was no significant difference in the incidence of delayed gr
View details →DOI: 10.23876/j.krcp.20.083 Negative / Null Result ReportOpen accessHuman anatomy
H. Çetin, S. Akkaşoğlu, S. Çalışkan · 2022 · Folia Morphologica
BACKGROUND: The aim of the study is to analyse the demographic and anatomical details of the Huschke’s foramen (HF) which have not been previously studied and to present a new clinical perspective. MATERIALS AND METHODS: Multidetector computed tomography (MDCT) images of 495 patients were retrospectively evaluated. Presence of a HF, its’ size, relations to side, age and gender were noted for every patient. Size of the foramen was measured in the axial plane, as well as on the reconstructed coronal and sagittal planes. RESULTS: Of the 495 patients 99 (20%) had HF. There was no significant diffe
View details →DOI: 10.5603/fm.a2021.0056 Negative / Null Result ReportOpen accessScience
I. Yahaya, Y. Ndatsu, A. Yunusa et al. · 2023 · Journal of Applied Sciences and Environmental Management
Proximate, electrolyte and biochemical profile of rabbits fed with Tridax residue meal replacing Vitamin and Mineral were evaluated in Lapai, Niger State, Nigeria using standard techniques. The dietary treatments evaluated were 20%, 40%, 60%, 80% and 0% inclusion level of Tridax. The results obtained did not follow any pattern except Urea, Globulin and Creatinine which had significant (P<0.05) decrease in the serum biochemical profile. The highest value for crude fat was seen in feed3 with value of 11.33±0.30 and the lowest was recorded in the control feed with value of 10.38±0.21. There was n
View details →DOI: 10.4314/jasem.v27i2.24 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
· 2014 · Gut and Liver
Background/AimsWe investigated the efficacy of prophylactic pancreatic stent placement for preventing postprocedure pancreatitis in patients undergoing endoscopic papillectomy.Methods : This retrospective study included 82 consecutive patients who underwent endoscopic papillectomy for benign ampullary neoplasm at Samsung Medical Center between August 2002 and June 2011. The patients were subdivided into two groups, namely, those who received prophylactic pancreatic stent placement and those who did not. Patient demographics, baseline blood test, tumor characteristics, and endoscopic treatment
View details →DOI: 10.5009/gnl.2014.8.3.306 Negative / Null Result ReportOpen accessTechnology
Laochareonsuk, T., Kaewtaro, S. · 2005 · Songklanakarin Journal of Science and Technology (SJST)
The optimal conditions of nata production from the fermentation of sugar palm syrup by Acetobacter xylinum TISTR 107 was studied. The results showed that optimized production for a litre of sugar palm syrup medium should compose 15 ºBrix concentration, 7.0 g NH4H2PO4 and 0.7 g MgSO4. 7 H2O at pH 4.25 and incubation at room temperature. The thickness of nata production reached 1.15 cm in 9 days. Sensory evaluation showed that there were no significant difference in odor and acceptability between the nata from sugar palm syrup and the traditional nata production from coconut juice whereas there
Negative / Null Result ReportOpen accessGeography. Anthropology. Recreation
Ratha Sor, Seanghun Meas, Ken K.Y. Wong et al. · 2014 · Journal of Limnology
The incidence and abundance of Monogononta rotifer species were recorded from lakes and reservoirs in the upper part of the Cambodian Mekong River basin in April and November 2010. One hundred and seven species are reported, 25 of which are new records to Cambodia and 8 taxa were unidentifiable to species level. Species richness at the regional and local scale was not significantly different between habitat types or between seasons, whether it was estimated using incidence or abundance data. Comparison of incidence data also revealed no significant difference from species richness of ponds con
View details →DOI: 10.4081/jlimnol.2014.995 Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities
Keljanović Anđela D. · 2021 · Zbornik Radova Filozofskog Fakulteta u Prištini
At the time when social psychologists believed they could be proud of their discipline, there was the devastating news that Diederik Stapel had committed a major scientific fraud. This event coincided with the start of the discussion on trust in psychological findings. It was soon followed by the report of a series of nine studies that failed to replicate the 'professor's study'. These replication results were astounding due to earlier reports of successful replications. Due to the crisis of confidence in the results of field research, the Open Science Collaboration subsequently replicated 100
View details →DOI: 10.5937/zrffp51-24851 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Mohamed Wishahi, Ahmed El Feel, Amr Elkhouly et al. · 2023 · BMC Urology
Abstract Background To compare the efficacy and safety of standard percutaneous nephrolithotomy (PCNL) with mini- PCNL for kidney stones 2–4 cm. Methods Eighty patients were enrolled in a comparative study, they were randomly divided into mini-PCNL group (n = 40) and standard-PCNL (n = 40). Demographic characteristics, perioperative events, complications, stone free rate (SFR) were reported. Results Both groups showed no significant difference in clinical data about age, stone location, back pressure changes, and body mass index. The mean operative time was (95 ± 17.9 min) in mini-PCNL, and (7
View details →DOI: 10.1186/s12894-023-01270-1 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Albert Le Floch, Guy Ropars · 2023 · Brain Sciences
When reading, dyslexic readers exhibit more and longer fixations than normal readers. However, there is no significant difference when dyslexic and control readers perform only visual tasks on a string of letters, showing the importance of cognitive processes in reading. This linguistic and cognitive processing requirement in reading is often perturbed for dyslexic readers by perceived additional letters and word mirror images superposed on the primary images on the primary cortex, inducing internal visual crowding. Here, we show that while for a normal reader, the number and the duration of f
View details →DOI: 10.3390/brainsci13101478 Negative / Null Result ReportOpen accessElementary particle physics
John K. Webb, Chung-Chi Lee, Dinko Milaković · 2022 · Universe
Recent advances in spectroscopic instrumentation and calibration methods dramatically improve the quality of quasar spectra. Supercomputer calculations show that, at high spectral resolution, procedures used in some previous analyses of spacetime variations of fundamental constants are likely to generate spurious measurements, biased systematically towards a null result. Developments in analysis methods are also summarised and a prescription given for the analysis of new and forthcoming data.
View details →DOI: 10.3390/universe8050266 Negative / Null Result ReportOpen accessPsychology
Caroline eBarras, Dirk eKerzel · 2016 · Frontiers in Psychology
It has been claimed that stimuli sharing the color of the nogo-target are suppressed because of the strong incentive to not process the nogo-target, but we failed to replicate this finding. Participants searched for a color singleton in the target display and indicated its shape when it was in the go color. If the color singleton in the target display was in the nogo color, they had to withhold the response. The target display was preceded by a cue display that also contained a color singleton (the cue). The cue was either in the color of the go or nogo target, or it was in an unrelated, neutr
View details →DOI: 10.3389/fpsyg.2016.00630 Negative / Null Result ReportOpen accessEducation (General)
Maik Beege, Maik Beege, Christoph Mengelkamp et al. · 2026 · Frontiers in Education
IntroductionThe disfluency effect proposes that deliberately introducing challenges or difficulties into the learning process can be advantageous. Particularly, perceptual disfluency (e.g., harder to read fonts) might affect learning positively. However, an ongoing debate persists regardxing the robustness of this effect, as some studies have failed to replicate it or have uncovered opposing outcomes.MethodsTo investigate potential moderators of the disfluency effect, two experiments were conducted using different types of instructional materials (instructional texts: N1 = 76; concept maps: N2
View details →DOI: 10.3389/feduc.2025.1731080 Negative / Null Result ReportOpen accessMedicine
Sabrina Lorenz, Birte Alex, Thomas Kammer · 2020 · PLoS ONE
Recently, modulatory effects of static magnetic field stimulation (tSMS) on excitability of the motor cortex have been reported. In our previous study we failed to replicate these results. It was suggested that the lack of modulatory effects was due to the use of an auditory oddball task in our study. Thus, we aimed to evaluate the role of an oddball task on the effects of tSMS on motor cortex excitability. In a within-subject-design we compared 10 minutes tSMS with and without oddball task. In one of the two sessions subjects had to solve an auditory oddball task during the exposure to the ma
View details →DOI: 10.1371/journal.pone.0233614 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Adam J.O. Dede, Wenyi Xiao, Nemanja Vaci et al. · 2025 · Molecular Autism
Abstract Background Autism is a complex neurodevelopmental condition, the precise neurobiological underpinnings of which remain elusive. Here, we focus on group differences in resting state EEG (rsEEG). Although many previous reports have pointed to differences between autistic and neurotypical participants in rsEEG, results have failed to replicate, sample sizes have typically been small, and only a small number of variables are reported in each study. Methods Here, we combined five datasets to create a large sample of autistic and neurotypical individuals (n = 776) and extracted 726 variable
View details →DOI: 10.1186/s13229-025-00647-3 Negative / Null Result ReportOpen accessPsychology
Singh, Anjali, Durand, Guillaume · 2022 · Tutorials in Quantitative Methods for Psychology
This study is a replication of Andreassen and colleagues (2013) [The relationships between behavioral addictions and the five-factor model of personality. Journal of Behavioral Addictions, 2(2), 90-99]. We partially replicated the findings of the original study. Our results support the role of personality, particularly conscientiousness, in predicting behavioral addictions, such as video game, Internet, and mobile phone addiction. However, we failed to replicate the same pattern of personality traits for each behavioral addiction.
View details →DOI: 10.20982/tqmp.18.1.r001 Negative / Null Result ReportOpen accessSocial Sciences
Briony D.
Pulford, Poonam
Gill · 2014 · Judgment and Decision Making
We report a series of experiments investigating the influence of feeling lucky or unlucky on people's choice of known-risk or ambiguous options using the traditional Ellsberg Urns decision-making task. We induced a state of feeling lucky or unlucky in subjects by using a rigged wheel-of-fortune game, which just missed either the bankrupt or the jackpot outcome. In the first experiment a large reversal of the usual ambiguity aversion effect was shown, indicating that feeling lucky made subjects significantly more ambiguity seeking than usual. However, this effect failed to replicate in five ref
Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Sung Hye Kong · 2026 · Endocrinology and Metabolism
For decades, vitamin D has been a cornerstone of preventive medicine. However, recent large-scale randomized controlled trials have failed to replicate the broad benefits previously observed in epidemiological studies, particularly with respect to fracture and fall prevention in vitamin D-replete populations. Moreover, growing evidence suggesting an increased fall risk associated with high-dose bolus administration has necessitated a re-evaluation of safety assumptions. This review synthesizes these discordant findings to propose a framework grounded in precision medicine. We explore the ‘dive
View details →DOI: 10.3803/enm.2026.2938 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Stella Aslibekyan, Marguerite R. Irvin, Bertha A. Hidalgo et al. · 2017 · Journal of Nutrition & Intermediary Metabolism
Background: Trimethylamine-N-oxide (TMAO), an atherogenic metabolite species, has emerged as a possible new risk factor for cardiovascular disease. Animal studies have shown that circulating TMAO levels are regulated by genetic and environmental factors. However, large-scale human studies have failed to replicate the observed genetic associations, and epigenetic factors such as DNA methylation have never been examined in relation to TMAO levels. Methods and results: We used data from the family-based Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) to investigate the heritable determi
View details →DOI: 10.1016/j.jnim.2017.03.002 Negative / Null Result ReportOpen accessMicrobiology
Miao Jiang, Pekka Kolehmainen, Laura Kakkola et al. · 2021 · Microbiology Spectrum
ABSTRACT The primary target organ of coronavirus disease 2019 (COVID-19) infection is the respiratory tract. Currently, there is limited information on the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to infect and regulate innate immunity in human immune cells and lung epithelial cells. Here, we compared the ability of four Finnish isolates of SARS-CoV-2 from COVID-19 patients to replicate and induce interferons (IFNs) and other cytokines in different human cells. All isolates failed to replicate in dendritic cells, macrophages, monocytes, and lymphocytes, and no in
View details →DOI: 10.1128/spectrum.00774-21 Negative / Null Result ReportOpen accessBiology (General)
Sancar Aziz, Mankinen Richard W, Lee Daekee et al. · 2006 · Journal of Circadian Rhythms
Abstract Background Recent studies have implicated the epidermal growth factor receptor (EGFR) within the subparaventricular zone as being a major mediator of locomotor and masking behaviors in mice. The results were based on small cohorts of mice homozygous for the hypomorphic Egfr wa 2 allele on a mixed, genetically uncontrolled background, and on intraventricular infusion of exogenous EGFR ligands. Subsequenlty, a larger study using the same genetically mixed background failed to replicate the original findings. Since both previous approaches were susceptible to experimental artifacts relat
View details →DOI: 10.1186/1740-3391-4-15 Negative / Null Result ReportOpen accessSocial Sciences
Christine M. Smith, Paulina Dzik, Errin Fornicola · 2019 · Social Influence
Using the lens of Deindividuation Theory, Leon Mann explored the formation of baiting crowds in a small sample of public suicides/suicide attempts. Instead of attempting to prevent the suicide, baiting crowds encourage the victim to jump. Our aim was to replicate Mann's study with a larger more diverse sample of suicide attempts and a broadened theoretical lens (Frustration-Aggression). Using ProQuest, we identified 152 public suicide attempts reported in English language newspapers and failed to replicate Mann’s findings. Rather, baiting crowd formation was associated with variables that incr
View details →DOI: 10.1080/15534510.2019.1669488 Negative / Null Result ReportOpen accessScience
Veronica Boyce, Maya Mathur, Michael C. Frank · 2023 · Royal Society Open Science
Cumulative scientific progress requires empirical results that are robust enough to support theory construction and extension. Yet in psychology, some prominent findings have failed to replicate, and large-scale studies suggest replicability issues are widespread. The identification of predictors of replication success is limited by the difficulty of conducting large samples of independent replication experiments, however: most investigations reanalyse the same set of [Formula: see text]. We introduce a new dataset of 176 replications from students in a graduate-level methods course. Replicati
View details →DOI: 10.1098/rsos.231240 