A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21328 results · page 480 of 711
Piralla A., BALDANTI, FAUSTO, MINOLI, LORENZO et al. · 2012
XMRV and polytropic MLV-related virus have been controversially associated with chronic fatigue syndrome (CFS). Subsequent reports failed to detect XMRV and MLV-related virus in CFS patients, and the previous results have been interpreted…
N. Stocchetti · 2014
Aggressive therapy after traumatic brain injury, for instance surgical decompression of the skull, is effective in reducing intracranial pressure. However in a randomized trial it has failed to improve outcome. Careful identification of…
Dr. Abu Elias Sarker, Dr. Mohammad Habibur Rahman · 2014
In spite of different approaches being experimented over the past six decades, poverty alleviation programs in the developing world have largely failed to improve poverty situation. Of all the factors responsible for the growing trend of…
Luisa Seguella (2806498), Stefano Gigli (2806501), Luca Steardo (214519) et al. · 2018
PEA failed to improve diarrhea course in PPARα−/− mice. HIV-1 Tat (130 ng/Kg)-induced diarrhea in PPARα−/− mice, increasing (a) daily defecation frequency, (b) average daily number of wet spots, and (c) fluid accumulation within 7 days…
John H. Strickler · 2018
Abstract Summary: Anti-EGFR therapies have failed to improve survival for unselected patients with metastatic gastroesophageal cancer, but in a subset of patients, EGFR amplification may predict treatment benefit. Maron and colleagues…
· 2022 · The Brown University Psychopharmacology Update
The antimuscarinic agent scopolamine did not demonstrate antidepressant effects in a randomized trial that used an active placebo comparator and involved 40 patients with major depressive disorder. Researchers stopped the trial for…
Julianna Rugor (548251), Lukasz Przybyl (548252), Ralf Dechend (252651) et al. · 2014
Masson trichrome staining of kidney sections (A) showed increased matrix deposition in vehicle-treated dTGR. Relaxin did not reduce matrix formation in the kidney (representative images). The upper panel shows a higher magnification. (B)…
Sharafuddin, Melhem, Katz, Daniel, Reddy, Geeta et al. · 2005
Monthly access flow monitoring with increased prophylactic angioplasty did not improve fistula patency.BackgroundRegular access monitoring is recommended to detect and treat access stenosis in order to prevent access thrombosis and…
Anna Kramvis (304621), Neil A. Martinson (198606), Trevor G. Bell (304619) et al. · 2013
“n” indicates the number of participants in each group. ALT and CD4 cell counts for each group are indicated in the table below the plot as “Median (Interquartile Range)”. Viral loads and CD4 cell counts did not differ significantly…
Oates, David, David Oates · 1976
The concentration of lead in fish muscle tissue from lakes where boating is heavy and where it is prohibited was measured. The lead levels ranged from less than 0.05 to 1.35 ppm but did not differ significantly between those in the…
Thomas Christian (2546665), Barbara Kabon (652817), David Emler (14540201) et al. · 2023
BackgroundIn relatively healthy middle-aged patients, recent studies have shown that supplemental oxygen did not significantly increase one-year mortality after noncardiac surgery. If supplemental oxygen influences long-term mortality,…
Nishida, Akira, 西田, 晃 · 2013
The Michelson-Morley experiment failed to detect evidence for the wind of luminiferous aether. However, the fact that light propagates without affecting aether wind on the rotating earth means that the medium is also rotating with us. For…
Ramage, Thomas R. · 2002
A quick look at the “No Significant Difference Phenomenon” website might leave the casual observer to the conclusion that an overwhelming amount of data exists to support the notion that technologically-mediated instruction and/or…
Alison Knopf · 2023 · Alcoholism & Drug Abuse Weekly
State laws that allow medical cannabis to be prescribed and dispensed did not result in the reduced treatment of chronic noncancer pain, researchers have found. In the study, “Effects of U.S. State Medical Cannabis Laws on Treatment of…
George Ampat, Emma Tixerant · 2019 · BMJ Case Reports
A 52-year-old woman sustained a direct soft tissue injury to the right knee following a fall onto the right knee. X-rays did not identify any bony injury. Physiotherapy decreased pain but instability persisted. MRI scans identified early…
Shrikhande, Milind, Fendler, Richard · 2012
Numerous studies show there is no significant difference between student performance in online versus traditional courses. Unfortunately, these studies are unable to identify how a given student would have performed in the other format.…
Camilla Fabbri, Timothy Powell-Jackson, Katherine Rodrigues et al. · 2023 · PLOS Global Public Health
EmpaTeach was the first intervention to address teacher violence to be tested in a humanitarian setting and the first to focus on reducing impulsive use of violence, but a cluster randomised trial found no evidence that the intervention…
Ibrahim Bashan, Turhan Toros · 2018 · Journal of Human Sciences
Aim: In this research it was aimed if there is a difference between mastery-performance climate and task-ego orientation variables of basketball players who did and did not experience a sports injury.Methods: This study group consists of…
· 2021 · The Brown University Psychopharmacology Update
A new study that confirmed the effect of topiramate in reducing heavy‐drinking days in patients with alcohol use disorder (AUD) did not find a moderating effect of the rs2832407 genotype on study outcomes. The latter finding contradicted…
Bob de Ruiter · 2023 · arXiv
In many fields of experimental science, papers that failed to replicate continue to be cited as a result of the poor discoverability of replication studies. As a first step to creating a system that automatically finds replication studies for a given paper, 334 replication studies and 344 replicated studies were collected. Replication studies could be identified in the dataset based on text content at a higher rate than chance (AUROC = 0.886). Additionally, successful replication studies could be distinguished from failed replication studies at a higher rate than chance (AUROC = 0.664).
Amritanshu Pandey, Marko Jereminov, Gabriela Hug et al. · 2017 · arXiv
Recent advances in power system simulation have included the use of complex rectangular current and voltage (I-V) variables for solving the power flow and three-phase power flow problems. This formulation has demonstrated superior convergence properties over conventional polar coordinate based formulations for three-phase power flow, but has failed to replicate the same advantages for power flow in general due to convergence issues with systems containing PV buses. In this paper, we demonstrate how circuit simulation techniques can provide robust convergence for any complex I-V formulation tha
James Kirby, Ioana Krehan, Michele Gubian · 2026 · arXiv
This study examines the extent to which the wav2vec2.0 architecture exhibits evidence of compensation for phonological context. We conducted a pseudo-replication of a perceptional compensation experiment on Mandarin Chinese tones, and compared the embedding similarities and probing classifier outputs between a purely self-supervised pre-trained model and a model fine-tuned for Mandarin ASR. No evidence of compensation was found in the embedding similarities of the purely pre-trained model. Probing classifiers showed some evidence of compensation in addition to the expected layer-wise improveme
Jaron Maene, Mingxiao Li, Marie-Francine Moens · 2021 · arXiv
The lottery ticket hypothesis states that sparse subnetworks exist in randomly initialized dense networks that can be trained to the same accuracy as the dense network they reside in. However, the subsequent work has failed to replicate this on large-scale models and required rewinding to an early stable state instead of initialization. We show that by using a training method that is stable with respect to linear mode connectivity, large networks can also be entirely rewound to initialization. Our subsequent experiments on common vision tasks give strong credence to the hypothesis in Evci et a
Robert McCarthy, Daniel C. H. Tan, Dominik Schmidt et al. · 2024 · arXiv
Scaling deep learning to massive and diverse internet data has driven remarkable breakthroughs in domains such as video generation and natural language processing. Robot learning, however, has thus far failed to replicate this success and remains constrained by a scarcity of available data. Learning from videos (LfV) methods aim to address this data bottleneck by augmenting traditional robot data with large-scale internet video. This video data provides foundational information regarding physical dynamics, behaviours, and tasks, and can be highly informative for general-purpose robots. This su
Nataša Pavlov, Ana Mitrašinović · 2025 · arXiv
The recent discovery of the most extended ultra-diffuse galaxy (UDG), Nube, has raised yet another question about the validity of the cold dark matter (CDM) model. The studies using cosmological and zoom-in simulations, which assume CDM, failed to replicate galaxies with the structural properties of Nube. However, the simulation box or the examined population of UDGs may be too narrow to fully capture the range of effects that can lead to the formation of such extraordinary galaxies. In this work we present a case study of a Nube-like galaxy from TNG100, the most extended simulated UDG examine
Jaroslaw Kornowicz · 2024 · arXiv
This study empirically examines the "Evaluative AI" framework, which aims to enhance the decision-making process for AI users by transitioning from a recommendation-based approach to a hypothesis-driven one. Rather than offering direct recommendations, this framework presents users pro and con evidence for hypotheses to support more informed decisions. However, findings from the current behavioral experiment reveal no significant improvement in decision-making performance and limited user engagement with the evidence provided, resulting in cognitive processes similar to those observed in tradi
Agnès Ferté, Kevin Hong · 2023 · arXiv
We highlight the role of weak lensing measurements from current and upcoming stage-IV imaging surveys in the search for cosmic inflation, specifically in measuring the scalar spectral index $n_s$. To do so, we combine the Dark Energy Survey 3 years of observation weak lensing and clustering data with BICEP/Keck, Planck and Sloan Digital Sky Survey data in $rΛ$CDM where $r$ is the tensor-to-scalar ratio. While there is no significant improvement in constraining power, we obtain a 1$σ$ shift on $n_s$. Additionally, we forecast a weak lensing and clustering data vector from the 10-year Legacy Sur
Karam Ahmed, Sherif Abuelenin, Heba Soliman et al. · 2015 · arXiv
V-BLAST detection method suffers large computational complexity due to its successive detection of symbols. In this paper, we propose a modified V-BLAST algorithm to decrease the computational complexity by reducing the number of detection iterations required in MIMO communication systems. We begin by showing the existence of a maximum number of iterations, beyond which, no significant improvement is obtained. We establish a criterion for the number of maximum effective iterations. We propose a modified algorithm that uses the measured SNR to dynamically set the number of iterations to achieve
Alp Atici · 2003 · arXiv
It is an established fact that for many of the interesting problems quantum algorithms based on queries of the standard oracle bring no significant improvement in comparison to known classical algorithms. It is conceivable that there are other oracles of algorithmic importance acting in a less intuitive fashion to which such limitations do not apply. Thus motivated this article suggests a broader understanding towards what a general quantum oracle is. We propose a general definition of a quantum oracle and give a classification of quantum oracles based on the behavior of the eigenvalues and ei
James Large, Paul Southam, Anthony Bagnall · 2018 · arXiv
tl;dr: no, it cannot, at least not on average on the standard archive problems. We assess whether using six smoothing algorithms (moving average, exponential smoothing, Gaussian filter, Savitzky-Golay filter, Fourier approximation and a recursive median sieve) could be automatically applied to time series classification problems as a preprocessing step to improve the performance of three benchmark classifiers (1-Nearest Neighbour with Euclidean and Dynamic Time Warping distances, and Rotation Forest). We found no significant improvement over unsmoothed data even when we set the smoothing param