Negative / Null Result ReportMedicine
Liu Y, Sun J, Hu Y et al. · 2026 · Clinical and experimental reproductive medicine
Objective Previous studies have reported a higher rate of small for gestational age (SGA) newborns from fresh embryo transfers compared with frozen-thawed embryo transfers (FET), potentially due to the supraphysiologic serum estradiol…
View details →DOI: 10.5653/cerm.2025.07969 Negative / Null Result ReportMedicine
Flensted-Jensen M, Kleis-Olsen AS, Weinreich CM et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)
Advanced glycation end-products (AGEs) accumulate with age and may contribute to skeletal muscle decline, yet their distribution within muscle compartments is unknown. Resistance training (RT) and high-intensity interval training (HIIT)…
View details →DOI: 10.1152/japplphysiol.01093.2025 Negative / Null Result ReportMedicine
Park JK, Lee JE, Kim JS et al. · 2026 · Journal of hazardous materials
Microplastics (MPs) are emerging contaminants that disrupt development, physiology, and redox homeostasis in aquatic organisms. However, their detailed impacts on amphibians and the potential for antioxidant-based mitigation remain poorly…
View details →DOI: 10.1016/j.jhazmat.2026.141609 Negative / Null Result ReportMedicine
Bahabri M, Figueiredo JN, Kara Y et al. · 2026 · Nanotechnology
In this study, the growth of vertical graphene (VG) nanosheets on copper (Cu) substrates in a direct-current plasma-enhanced chemical vapor deposition (PECVD) system was studied. The plasma process during the VG growth was characterized…
View details →DOI: 10.1088/1361-6528/ae38e9 Negative / Null Result ReportMedicine
Lake J, Mariniello M, Schiano G et al. · 2026 · Journal of the American Society of Nephrology : JASN
Key points Lipocalin-2 upregulation paralleled intracellular uromodulin aggregates in mouse and cellular models of autosomal dominant tubulointerstitial kidney disease because of pathogenic uromodulin. The induction of lipocalin-2 was…
View details →DOI: 10.1681/asn.0000001077 Negative / Null Result ReportMedicine
Spry ER, Travis KB, Ragland KJ et al. · 2025 · Molecular and cellular endocrinology
Aims Semaglutide (SEMA) is a glucagon-like peptide-1 receptor agonist (GLP-1RA) that has recently emerged as a popular pharmacological treatment for type 2 diabetes and insulin resistance due to its weight loss properties. Previous studies…
View details →DOI: 10.1016/j.mce.2025.112629 Negative / Null Result ReportMedicine
Bos MD, Ho CSL, Meyer NH et al. · 2026 · The Journal of surgical research
Introduction Epidemiological studies indicate that physical activity reduces cancer risk and mortality, while sedentary behavior exerts opposite effects. However, their impact on tumor metastasis remains unclear. This study investigated…
View details →DOI: 10.1016/j.jss.2026.02.023 Negative / Null Result ReportMedicine
Sogawa K, Funada M · 2026 · Toxicology letters
Cannabidiol (CBD) is a non-psychoactive cannabinoid with increasing global use, yet safety data during pregnancy remain limited. Preclinical studies suggest possible developmental neurotoxicity. Here, we examined the effects of CBD…
View details →DOI: 10.1016/j.toxlet.2025.111812 Negative / Null Result ReportOpen accessMedicine
Takata M, Nishikawa M, Hayashi H et al. · 2025 · Cureus
Background It remains unclear whether omecamtiv mecarbil, a cardiac myosin direct activator, enhances vascular smooth muscle myosin function at clinical and supra-clinical doses. Aims The current study evaluated the effect of omecamtiv…
View details →DOI: 10.7759/cureus.87854 Negative / Null Result ReportMedicine
Day AS, Ballard TM, Benetti M et al. · 2026 · Journal of the Academy of Nutrition and Dietetics
Background The "gold standard" for successful blinding in controlled food-based dietary interventional trials includes a sham diet. Objective This study aimed to develop and evaluate a sham diet intended for use as a comparator in…
View details →DOI: 10.1016/j.jand.2026.156345 Negative / Null Result ReportMedicine
Hancock G, Batterby E, Dovers E et al. · 2026 · Emergency medicine Australasia : EMA
Background Point-of-care ultrasound (POCUS) is widely used in emergency departments (ED) and has potential value during cardiac arrest for identifying reversible causes (e.g., pericardial effusion, pneumothorax and pulmonary embolism) and…
View details →DOI: 10.1111/1742-6723.70209 Negative / Null Result ReportMedicine
Sun Q, Miao Z, Bian L et al. · 2026 · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Methionine oxidation in monoclonal antibodies (mAbs) could critically compromise drug stability and efficacy. This investigation comprehensively evaluated the structural and functional impacts of oxidation on a mAb An under long-term…
View details →DOI: 10.1016/j.jchromb.2026.124920 Negative / Null Result ReportMedicine
Messanh KV, Muhie Ddine M, Ambrosini V et al. · 2026 · Journal of photochemistry and photobiology. B, Biology
Botrytis cinerea (B. cinerea) is a fungus with a high mutation rate and infects more than 200 plant species, causing significant yield losses. Therefore, new strategies to fight against this ubiquitous phytopathogen are highly sought…
View details →DOI: 10.1016/j.jphotobiol.2026.113365 Negative / Null Result ReportMedicine
Palner M, Kolesnik E, Baun C et al. · 2026 · Neuropharmacology
Mammalian brain may contain an endogenous pool of the psychedelic substance N,N-dimethyltryptamine (DMT), which may act as a co-transmitter with serotonin (5-HT). We tested the joint hypotheses that endogenous DMT would accumulate in rat…
View details →DOI: 10.1016/j.neuropharm.2026.110874 Negative / Null Result Report
Navez M, Gilbo N, Vandermeulen M et al. · 2026 · Preprint
Abstract Background Kidney transplantation from donation after circulatory death (DCD) donors is increasingly used but remains associated with warm ischemic injury. Normothermic machine perfusion (NMP) enables functional assessment and…
View details →DOI: 10.21203/rs.3.rs-8308681/v1 Negative / Null Result Report
Baltin ME, Shulman AA, Nikulina MI et al. · 2025 · Preprint
Immersive virtual reality (VR) technologies are being increasingly applied in clinical settings, physiotherapy, and neurorehabilitation due to their potential to modulate neurophysiological functions. However, the mechanistic basis of VR’s…
View details →DOI: 10.1101/2025.11.26.690873 Negative / Null Result ReportMedicine
Stub M, Ramhøj L, Axelstad M et al. · 2026 · Reproductive toxicology (Elmsford, N.Y.)
Perfluorooctane sulfonate (PFOS) and tetrabromobisphenol A (TBBPA) are environmental pollutants with known endocrine disrupting potential. Both substances display various thyroid hormone (TH) system disrupting effects, both in vitro and in…
View details →DOI: 10.1016/j.reprotox.2026.109170 Negative / Null Result ReportOpen accessMedicine
Panzenböck LF, Abdel Nour G, Dürrschnabel DL et al. · 2026 · Global spine journal
Study DesignRandomized controlled trial.ObjectivesTo characterize postoperative C-reactive protein (CRP) trajectories as predictors of surgical site infection (SSI) following lumbar spine surgery, to determine optimal CRP thresholds, and…
View details →DOI: 10.1177/21925682261450878 Negative / Null Result ReportMedicine
Yardimci A, Ertugrul NU, Akkoc RF et al. · 2026 · Reproductive biology
Ozone (O₃) has been used to treat various diseases for many years, with most preclinical studies focusing on its effects in conditions such as testicular torsion and ischemia-reperfusion injury; however, its impact on male reproductive…
View details →DOI: 10.1016/j.repbio.2026.101185 Negative / Null Result ReportMedicine
Wang CI, Cho YC, Lin YP · 2025 · Environmental Technology & Innovation
Harmful asbestos-containing waste is generated during old building demolition. This study aims to develop a thermal-chemical treatment method to detoxify asbestos-containing waste and explore the potential use of detoxified…
Negative / Null Result ReportMedicine
Kęska P, Zielińska D, Karbowiak M et al. · 2025 · Food Chemistry
The aim of this study was to evaluate the effectiveness of cell-free supernatants (CFS) produced by selected lactic acid bacteria (LAB) strains: Lacticaseibacillus paracasei B1 and Lactiplantibacillus plantarum O24 as antioxidant and…
Negative / Null Result ReportOpen accessMedicine
Patoglu OR, Horne RSC, Mann DL et al. · 2026 · European journal of pediatrics
A hallmark of Prader-Willi syndrome (PWS) is hypothalamic-pituitary axis dysfunction, which can result in reduced growth hormone (GH) production. While GH replacement therapy is common in children with PWS, it has also been implicated in…
View details →DOI: 10.1007/s00431-026-06857-y Negative / Null Result ReportMedicine
Eser M, Yazıcı C, Kandemir Ü et al. · 2026 · Research in veterinary science
Ivermectin (IVR) is a semi-synthetic macrocyclic lactone widely used against nematodes. Under physiological conditions, its central nervous system (CNS) penetration is limited by P-glycoprotein-mediated efflux at the blood-brain barrier…
View details →DOI: 10.1016/j.rvsc.2026.106105 Negative / Null Result Report
Targhetta VP, Vieira RdS, Ranfley H et al. · 2025 · Preprint
Inflammasomes are multiprotein complexes that activate pro-caspase-1, leading to the maturation of the pro-inflammatory cytokines IL-1β and IL-18. Nlrp1 , the first receptor identified with inflammasome-forming capacity, is highly…
View details →DOI: 10.1101/2025.11.24.690170 Negative / Null Result ReportMedicine
Farber C, Jackson C, Renteria K et al. · 2026 · Nutrition (Burbank, Los Angeles County, Calif.)
Background Exposure to a Western diet during gestation and lactation adversely impacts offspring mood, learning, and memory. We determined if high dose maternal methyl donor nutrient (MDN) supplementation ameliorated the effects of a high…
View details →DOI: 10.1016/j.nut.2026.113149 Negative / Null Result ReportMedicine
Khaliji E, Marycz K, Horna M et al. · 2025 · American journal of veterinary research
Objective To evaluate IA autologous platelet-derived mitochondrial preparation versus vehicle control in a bilateral lipopolysaccharide (LPS)-induced model of equine synovitis. Methods 2 ng of LPS was injected into bilateral intercarpal…
View details →DOI: 10.2460/ajvr.25.05.0187 Negative / Null Result Report
Rodriguez CG, Choolani M, Illanes S · 2025 · Preprint
Objective: To study variation in moral attitudes toward selective abortion in case of prenatal diagnosis of a disability in the general population. Methods: 926 participants completed a survey in which they expressed their moral views…
View details →DOI: 10.31234/osf.io/avs6c_v2 Negative / Null Result Report
Rodriguez CG, Choolani M, Illanes S · 2025 · Preprint
Objective: To study variation in moral attitudes toward selective abortion in case of prenatal diagnosis of a disability in the general population. Methods: 926 participants completed a survey in which they expressed their moral views…
View details →DOI: 10.31234/osf.io/avs6c_v1 Negative / Null Result Report
VanRyzin JW, Laraia GA, Gyawali U et al. · 2025 · Preprint
ABSTRACT Astrocyte dysfunction within the nucleus accumbens (NAc) has been increasingly implicated in maladaptive reward processing and the development of addiction-like behaviors. In this study, we investigated how impairing astrocyte…
View details →DOI: 10.1101/2025.10.20.683571 Negative / Null Result ReportMedicine
Quan F, Ma J, Zhao Y et al. · 2025 · Aquaculture international
This study investigated the effects of supplementing high soybean meal diets with alpha-ketoglutaric acid (AKG) on the intestinal health and growth performance of spotted sea bass (Lateolabrax maculatus). A total of 270 fish (average…
