A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19878 results in Negative / Null Result Report · page 465 of 663
Bakir M, Sağmak S · 2026 · BMC oral health
Background This study aimed to evaluate the effects of different modeling resins on the surface roughness, surface gloss, and color stability of a nanohybrid resin composite. Methods Forty disk-shaped specimens (10 mm diameter × 2 mm…
Kaplan S, de Nascimento J, Contini A · 2026 · Drug safety
Background and objectives Concerns about modafinil and armodafinil use in pregnancy emerged from animal reproductive toxicity and limited human data, including a US registry suggesting increased risk of major congenital malformations…
McDonough W, Gevorkian J, Wong D et al. · 2026 · Surgical laparoscopy, endoscopy & percutaneous techniques
Background As part of the accreditation process for bariatric surgery, patients must go through a preoperative pathway. There will inevitably be patients who are seen in the clinic but never undergo surgery. This rate of attrition is…
Wakui N, Ogino Y, Nagumo H et al. · 2026 · BMC gastroenterology
Background Zinc deficiency is common in chronic liver disease and is closely associated with the progression of hepatic fibrosis and metabolic dysfunction. Although pemafibrate, a selective peroxisome proliferator-activated receptor alpha…
Biedermann M, Sifakakis I, Zinelis S et al. · 2026 · European journal of oral sciences
Rubbing phosphoric acid during etching has been shown to improve surface roughness in prepared enamel. This study aimed to compare intact enamel's surface roughness and resin tag lengths after etching with and without rubbing. Extracted…
Hamid R, Bayramoğlu MN, Şirolu S et al. · 2026 · Journal of clinical medicine
Background: In this study, we radiologically assessed potential increases in microvascularity, extracellular matrix-related changes, and tissue viscoelasticity following carboxytherapy for periorbital hyperpigmentation (POH). We also…
Akbulut NK, Yıldız I, Yılmaz MT · 2026 · Polish journal of veterinary sciences
Melatonin not only regulates circadian rhythms in animals but also supports reproductive health through its potent antioxidant properties and immunomodulatory effects. In this study, the effects of exogenous melatonin administration on…
Firoozjaei IT, Sabzi Z, Rajabloo M et al. · 2026 · Nursing research and practice
Background During pregnancy, extensive hormonal and metabolic changes can occur. Gestational diabetes can cause maternal and neonatal complications. Follow-ups have shown that women who first develop metabolic diseases during pregnancy…
Şenel SSD, Çetin A · 2026 · BMC psychology
Peer bullying poses a serious risk to adolescents' psychosocial development and school adjustment. However, culturally adapted and evidence-based intervention programs remain limited in non-Western societies. Restorative justice approaches…
Ebrahimi S, Tehrani H, Ghavami V et al. · 2025 · Journal of education and health promotion
Background Brucellosis is a major bacterial infectious disease common to human beings and animals. It is considered a prevalent infection in developing countries. The present research was carried out to explore the effect of an educational…
Bilgin O, Koç M · 2026 · Behavioral sciences (Basel, Switzerland)
Solution-focused brief group counseling is a systematic approach that centers on solutions rather than the problem itself. In this approach, which focuses on the strengths of the clients, the solutions are generated by the clients…
Sahu SK, Nayak M, Samal A et al. · 2026 · Preprint
Abstract Hypothyroidism has been associated with cognitive disorders and high risk of neurodegenerative disorders like Alzheimer's disease (AD), which is caused by amyloid-β (Aβ) accumulation in brain. The aim of the study is to examine…
Kawahata D, Biber D · 2026 · Journal of health psychology
The purpose of this study was to evaluate the impact of the Mindless to Mindful (M2M) program on fat mass, executive function, exercise identity, and exercise habit strength. A total of 89 adults consented to participate in the M2M…
Chaudhry AS, Tian W, Adam TH et al. · 2026 · Aesthetic surgery journal
Background Biologic and targeted immune-modulating agents are increasingly used to manage autoimmune diseases like rheumatoid arthritis, psoriasis, and inflammatory bowel disease. As more patients receiving these therapies undergo elective…
Rahimi MR, Morton AB, Golpasandi H et al. · 2025 · BMC sports science, medicine & rehabilitation
Background Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes. This double-blind, randomized, placebo-controlled trial investigated CoQ10's effects on cardiac stress…
Karaaslan O, Türkyılmaz G, Hacıoğlu L et al. · 2026 · Biomedicines
Background/Objectives: Therapeutic plasma exchange (TPE) is an extracorporeal treatment used in thrombotic microangiopathies (TMAs) and various autoimmune and neurological disorders. However, data regarding its use during early pregnancy…
Long L, Liu G, Gao G et al. · 2026 · Insects
The effects of substituting soybean meal with black soldier fly larvae (BSFL) meal on the growth performance, immunological response, intestinal morphology, and gut microbiota of Pekin ducks were assessed. A total of 150 one-day-old Pekin…
Lober A, Eaton CM, Burnette S et al. · 2026 · Nursing for women's health
Objective To evaluate the impact of an evidence-based respectful maternity care program on registered nurses' attitudes and beliefs about childbirth practices across multiple U.S. hospital maternity and neonatal units. Secondary objectives…
Yang F, Ma Y, Li X et al. · 2026 · Life (Basel, Switzerland)
This study aims to investigate the effects of cysteamine zinc supplementation on milk production, composition, amino acid profile, and metabolites in mares. Building on prior experimental findings, a dose of 7 mg/kg body weight of CS-Zn…
Schreiber R, Ousingsawat J, Kunzelmann K · 2026 · Cellular and molecular life sciences : CMLS
We previously reported a loss of T cell activation following knockdown of the phospholipid scramblase and ion channel ANO9 (TMEM16J) in human Jurkat lymphocytes. We have now analyzed in detail the role of ANO9 in Jurkat ANO9 knockout cells…
Hafeez A, Saleem U, Naz S et al. · 2026 · Veterinary medicine and science
The objective of this study was to investigate the ameliorative effect of betaine on the performance, blood biochemistry, intestinal lesion score and nutrient utilization of broiler chickens exposed to coccidian challenge. A total of 600…
Saud MA, Khamees Abed S, Shahooth MA et al. · 2026 · Preprint
Background: While ivermectin is a common antiparasitic drug used in veterinary medicine, the effects of repeated administration at therapeutic doses have not been well studied. Of particular interest is the impact of ivermectin on…
Moreira-Vera D, Solórzano MLP, Marín-Pérez AL · 2026 · Preprint
Abstract Introduction: Ethical decision-making is a core competency in medical training. However, evidence regarding moral reasoning and ethical sensitivity among medical students in Latin America remains limited, particularly in settings…
Hamsika V, Batra P, Bhaskar V et al. · 2026 · Pediatric emergency care
Objective To compare IVC/Ao ratio, IVC collapsibility/distensibility indices before and after the administration of fluid bolus therapy in children with non-hemorrhagic shock using point of care ultrasound, and to correlate the changes in…
Ali ET, Findlay BL · 2026 · Preprint
Sustainable agriculture has driven increased exploration of microbial inoculants as a promising strategy to boost plant growth for higher yield and enhance secondary metabolism to increase crop nutritional value. However, their influence…
Wang W, Chen Z, Li M et al. · 2026 · Preprint
Fundus fluorescein angiography (FFA) is the gold standard for assessing diabetic retinopathy (DR) severity, but whether different contrast diffusion times affect staging remains unclear. Following two clinical DR staging criteria, we…
Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
Marani N, di Gennaro D, Garotti R et al. · 2026 · Frontiers in psychiatry
Introduction Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The…
Ansari D, Bethel JA, Greeneway GP et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)
Background and objectives Lateral interbody fusion represents a minimally-invasive approach to achieve indirect decompression via disc height restoration and alignment correction in patients with degenerative lumbar spondylolisthesis. If…
White RL, Read QD, Valles SM · 2026 · Journal of invertebrate pathology
Solenopsis invicta virus 3 (SINV3) is a biological control agent against the red imported fire ant, S. invicta. We attempted to improve the virus' effectiveness with organosilicone adjuvants hydroxy trisiloxane [hydroxyTSX] and methoxy…