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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19875 results in Negative / Null Result Report · page 437 of 663

Negative / Null Result ReportMedicine

Analysis of Contrast-enhanced CT Radiation Dose in Children.

Wang F, Sheng J, Zhang G et al. · 2026 · Health physics

Reducing radiation exposure in pediatric imaging is a key focus globally, and it is necessary to establish diagnostic reference levels (DRLs) for contrast-enhanced computed tomography (CT) in children. This study assesses typical radiation…

View details →DOI: 10.1097/hp.0000000000002147
Negative / Null Result ReportMedicine

Investigation of the effectiveness of different suture materials used in impacted mandibular third molar extractions on wound healing and clinical features.

Ömezli MM, Torul D, Doğanay Z · 2026 · Quintessence international (Berlin, Germany : 1985)

Purpose The aim of this study was to explore the physical and clinical efficacy of different suture materials used following impacted third molar surgery. Patients and methods This retrospective study included patients who underwent…

View details →DOI: 10.3290/j.qi.b7021105
Negative / Null Result Report

Short-term HPV detection dynamics across hormonal contraceptive methods in adolescent girls and young women: a secondary analysis of a randomized trial in South Africa

Tanko RF, Taku O, Mbulawa ZZA et al. · 2026 · Preprint

Abstract Background Human papillomavirus (HPV) is highly prevalent in adolescent girls and young women (AGYW) in sub-Saharan Africa. We evaluated short-term differences in HPV prevalence and early detection dynamics across hormonal…

View details →DOI: 10.21203/rs.3.rs-9663118/v1
Negative / Null Result ReportOpen accessMedicine

Metabolic profiles show few differences in serum amino acid, one-carbon, and fatty acid compounds in dogs fed a plant-based ("vegan") or meat-based diet.

Dodd SAS, Adolphe JL, Shoveller AK et al. · 2025 · Frontiers in veterinary science

Introduction Dogs are omnivores, not herbivores, and yet entirely plant-based diets are formulated to meet their current known nutrient recommendations. However, little is known about the metabolic effects of feeding diets containing no…

View details →DOI: 10.3389/fvets.2025.1706965
Negative / Null Result ReportMedicine

Optimal MRI sequence for predicting extraprostatic extension in prostate cancer: comparison of LCC and MaxRADD measurements.

Ilanjian G, Matthey J, Porões F et al. · 2026 · Abdominal radiology (New York)

Objectives Accurate preoperative identification of extraprostatic extension (EPE) in prostate cancer (PCa) is important for treatment strategies. This retrospective study aimed to determine which MRI sequence provides the most accurate…

View details →DOI: 10.1007/s00261-026-05615-w
Negative / Null Result ReportMedicine

Early osseointegration of two in-house 3D-printed porous titanium implant designs: an <i>in vivo</i> sheep study.

Borgognoni AB, Freund SS, Baas J et al. · 2026 · Frontiers in surgery

Introduction Early osseointegration is critical for long-term implant stability, and in-house 3D-printed porous surfaces may enhance bone integration by promoting cellular migration and tissue formation, provided that porosity is balanced…

View details →DOI: 10.3389/fsurg.2026.1818355
Negative / Null Result Report

Prophylactic and Therapeutic Hydroxychloroquine and Zinc Administration Do Not Exert Synergistic Renal Protection in a Rat Sepsis Model

CUMHUR BA, ACIKSARI K, DOLANBAY EG et al. · 2026 · Preprint

Abstract Purpose The aim of this study was to evaluate whether combined administration of hydroxychloroquine and zinc cause more damage or synergistic protection against sepsis-induced renal injury in a cecal ligation and puncture (CLP)…

View details →DOI: 10.21203/rs.3.rs-9646606/v1
Negative / Null Result ReportMedicine

Comparison of first trimester complete blood count parameters in missed abortion and healthy pregnant women: a retrospective case-control study.

Tural E, Coşkun ADE, Demi̇r D et al. · 2026 · BMC pregnancy and childbirth

Background The aim of our study is to compare the markers and parameters obtained from complete blood count between patients diagnosed with missed abortion in the first trimester and a healthy pregnant control group. Materials and methods…

View details →DOI: 10.1186/s12884-026-09443-0
Negative / Null Result ReportOpen accessMedicine

Physiological and growth responses to replacing corn gluten with corn fermented protein in diets for juvenile European sea bass: growth performance, intestinal morphology and fillet quality.

Yılmaz E, Güler M, Midilli S et al. · 2026 · Fish physiology and biochemistry

This study evaluated the effects of replacing corn gluten with corn fermented protein in the diets of European sea bass (Dicentrarchus labrax) juveniles (25.9 ± 0.2 g) during a 60-day feeding trial. Four experimental diets were prepared by…

View details →DOI: 10.1007/s10695-026-01710-3
Negative / Null Result ReportMedicine

Neuromuscular and Subjective Recovery Responses to Day and Night Fixtures During Congested and Noncongested Microcycles in Professional Soccer Players.

Mukandi I, Turner A, Bishop C et al. · 2026 · Journal of strength and conditioning research

Abstract Mukandi, I, Turner, A, Bishop, C, Beato, M. Neuromuscular and subjective recovery responses to day and night fixtures during congested and noncongested microcycles in professional soccer players. J Strength Cond Res XX(X):…

View details →DOI: 10.1519/jsc.0000000000005508
Negative / Null Result ReportMedicine

Influence of menstrual cycle phases on post-endodontic pain: a comparative clinical study with male patients.

Çıkman AŞ, Öksüzer MÇ, Hatipoğlu Ö et al. · 2026 · Odontology

Post-endodontic pain is a major concern that negatively impacts patients' quality of life. To date, there is no study examining the effect of the menstrual cycle on post-endodontic pain. Thus, this study aimed to elucidate any significant…

View details →DOI: 10.1007/s10266-026-01410-7
Negative / Null Result ReportMedicine

More pronounced effects of the extent of discectomy over the extent of laminectomy on postoperative biomechanics and clinical outcomes in unilateral biportal endoscopy for lumbar disc herniation.

Wang F, Wang T, Lu G et al. · 2026 · Journal of orthopaedic surgery and research

Background Unilateral biportal endoscopy (UBE) can be performed to treat lumbar disc herniation (LDH). Nevertheless, the postoperative clinical outcomes and spinal biomechanical implications following partial discectomy and laminectomy,…

View details →DOI: 10.1186/s13018-026-06955-5
Negative / Null Result ReportOpen accessMedicine

Radiofrequency Fields at 2.45 GHz Reprogram Mitochondria-Lysosome Crosstalk and Modulate the Survival/Death of Macrophages Exposed to LPS and/or the SARS-CoV-2 Spike Protein.

Sueiro-Benavides RA, Leiro-Vidal JM, Rodríguez-González JA et al. · 2026 · International journal of molecular sciences

The redox mechanisms of RAW 264.7 macrophages exposed to 2.45 GHz RF-EMF at subthermal specific absorption rates and to lipopolysaccharide (LPS) and/or the SARS-CoV-2 spike protein (CSP) were investigated. To this end, cellular responses…

View details →DOI: 10.3390/ijms27093813
Negative / Null Result ReportOpen accessMedicine

Toxicological Relevance of Biogenic Amines in Honey: Dietary Exposure and Integrated Risk Indicators in Algerian and Moroccan Honeys.

Bruno F, Bruschetta G, Miller A et al. · 2026 · Foods (Basel, Switzerland)

Biogenic amines are nitrogenous compounds that may occur in foods through plant metabolism, bee enzymatic activity, or microbial decarboxylation. This study evaluated biogenic amines content in monofloral honeys from Algeria and Morocco,…

View details →DOI: 10.3390/foods15081411
Negative / Null Result ReportMedicine

[Analysis of the prevalence characteristics and trends of allergen-specific IgE levels in a children's hospital in Wuhan City from 2019 to 2024].

Liu YH, Du Q, Zhang MR et al. · 2026 · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

Objective: To investigate the changes in the positive rate of specific immunoglobulin E (sIgE) for inhalant and ingestive allergens in children at a certain children's hospital in Wuhan City from 2019 to 2024, and to analyze the…

View details →DOI: 10.3760/cma.j.cn112150-20250828-00834
Negative / Null Result ReportMedicine

Local Delivery of Tranexamic Acid and Dexamethasone via Piezoelectric Irrigationin Rhinoplasty: A Prospective Double-Blind Comparative Study of Early Postoperative Morbidities.

Gunay G, Ece M, Beloglu Tonyali Y et al. · 2026 · The Journal of craniofacial surgery

This study aimed to evaluate the effects of adding tranexamic acid (TXA) and dexamethasone to the irrigation solution of a piezoelectric device during open rhinoplasty on postoperative periorbital edema, ecchymosis, and pain. In this…

View details →DOI: 10.1097/scs.0000000000012827
Negative / Null Result ReportOpen accessMedicine

Microscopic and computational analysis of the stomach, duodenum, and liver of rats with induced hyperprolactinemia treated with exogenous melatonin.

da Silva JV, da Silva RC, Ferreira RGDS et al. · 2026 · Frontiers in veterinary science

Introduction This study evaluated the effects of exogenous melatonin (MEL) on morphological and computational alterations in the stomach, duodenum, and liver of hyperprolactinemic rats. Methods Twenty-four animals were divided into three…

View details →DOI: 10.3389/fvets.2026.1709295
Negative / Null Result ReportMedicine

Assessment of Plant and Soil Heavy Metal Pollution in an Abandoned Mining Area in Türkiye.

Hüseyinova R, Kutbay HG, Basançelebi O et al. · 2026 · Bulletin of environmental contamination and toxicology

This study was conducted in the northeast of Türkiye in an abandoned mine area. There were significant differences between study sites with respect to all heavy metals in the leaves of tree species. Statistically significant differences…

View details →DOI: 10.1007/s00128-026-04248-5
Negative / Null Result ReportMedicine

The application of internal ring closure in laparoscopic transabdominal preperitoneal (TAPP) repair for large indirect inguinal hernias: a retrospective study of 162 cases.

Liu M, Shen X · 2026 · Langenbeck's archives of surgery

Purpose Patients with primary unilateral indirect inguinal hernias and large internal inguinal rings have a higher incidence of seroma formation following laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This study aims to…

View details →DOI: 10.1007/s00423-026-04102-6
Negative / Null Result Report

The effect of freeze-drying and storage on lactobacilli strains isolated from the gastrointestinal tract of wild boars using different cryoprotectants

Kavanova K, Babak V, Crhanova M · 2026 · Preprint

Abstract Probiotics play an important role in maintaining gastrointestinal comfort and health in piglets. For this reason, lactobacilli isolated from the gastrointestinal tract of domestic pigs and wild boars are evaluated for probiotic…

View details →DOI: 10.21203/rs.3.rs-9480160/v1
Negative / Null Result ReportMedicine

Acetabular cup orientation differs across surgical approaches in primary total hip arthroplasty: a retrospective analysis.

Chimeno-Pigrau C, Fernández-Valencia JA, Alías A et al. · 2026 · International orthopaedics

Purpose Accurate acetabular cup positioning is crucial in primary total hip arthroplasty (THA), as malposition is associated with instability and early failure. We hypothesized that acetabular cup orientation may differ according to the…

View details →DOI: 10.1007/s00264-026-06873-5
Negative / Null Result ReportOpen accessMedicine

Psychostimulant effects on motor and cognitive function in adults attention deficit hyperactivity disorder.

Cundari M, Kanold L, Bergwall D et al. · 2026 · The international journal of neuropsychopharmacology

Objectives This study aims to compare the performance on motor and cognitive functions of adult patients with attention deficit hyperactivity disorder (ADHD) with or without psychostimulant medication and controls. A secondary objective is…

View details →DOI: 10.1093/ijnp/pyag013
Negative / Null Result ReportOpen accessMedicine

Does alignment with Roussouly classification improve outcomes in well-aligned adult spinal deformity patients?

Kaghazchi A, Karnati J, Ashraf A et al. · 2026 · Surgical neurology international

Background Correction of adult spinal deformity (ASD) using the Roussouly classification, SRS-Schwab classification, or the global alignment and proportion (GAP) score is associated with reduced mechanical complications. However, the…

View details →DOI: 10.25259/sni_404_2026
Negative / Null Result ReportOpen accessMedicine

Effects of fermented palm kernel cake on growth performance, intestinal health, cecal microbiota, and ammonia emission in broilers.

Li J, Chen Z, Huang R et al. · 2026 · Poultry science

This study was conducted to evaluate the effects of fermented palm kernel cake (FPKC) on growth performance, intestinal health, cecal microbiota, nitrogen metabolism, and ammonia emission reduction of broiler chickens. A total of 900…

View details →DOI: 10.1016/j.psj.2026.107162
Negative / Null Result ReportMedicine

Obstetric and perinatal outcomes in twin pregnancies conceived through assisted reproduction: A retrospective cohort study.

Izbizky GH, Sevillano G, Abramor RM et al. · 2026 · Archivos argentinos de pediatria

Introduction. Multiple pregnancies are more frequently associated with adverse maternal and neonatal outcomes. The incidence of multiple pregnancies has increased with the use of assisted reproductive technologies (ART): they account for…

View details →DOI: 10.5546/aap.2025-10997.eng
Negative / Null Result ReportMedicine

Feasibility of Capillary Self-Collected Blood Specimens for Routine Outpatient Laboratory Testing.

Swartchick CB, Gurudu R, Lexvold NS et al. · 2026 · The journal of applied laboratory medicine

Background Capillary self-collection (CSC) devices allow patients to collect blood samples at home, potentially reducing outpatient phlebotomy visits. This study aimed to (a) assess the patient experience with multiple commercially…

View details →DOI: 10.1093/jalm/jfag075