Failed Experiment ReportOpen accessMedicine
Omole-ohonsi A, Ashimi AO · 2008 · Ibom Medical Journal
Objective: To evaluate the feasibility and outcome of caesarean myomectomy. Patients and Methods: A retrospective study of cases of caesarean myomectomy at the Aminu Kano Teaching Hospital, Kano, Nigeria, a tertiary health facility in a developing country between January 1998 and December 2004. Outcome Measures: Age and parity of the women, number, size and location of fibroids, duration of operation, estimated blood loss, postoperative complications and duration of hospital stay. Results: Sixteen cases of caesarean myomectomy were done during the study period using the tourniquet method. It i
View details →DOI: 10.61386/imj.v3i2.25 Failed Experiment ReportOpen accessMedicine
Yi Zhan, Huiming Yang, Jiangtao Wang et al. · 2024 · Scientific Reports
Abstract Based on the characteristics of Kummell’s disease (KD) and related anatomical structures of the thoracolumbar spine, a novel bone cement screw system has been designed to effectively avoid the cement loosening and displacement. This experiment aimed to assess the biological effects of the novel bone cement screw system in KD on fresh cadaveric thoracolumbar spine specimens, thereby discussing its potential application value and providing a foundation for clinical implementation. This study employed a total of 50 fresh female adult cadaver specimens. Each specimen underwent extraction
View details →DOI: 10.1038/s41598-024-77511-6 Negative / Null Result ReportOpen accessDentistry
Polavarapu Venkata Ravi Chandra, Vemisetty Hari Kumar, Surakanti Jayaprada Reddy et al. · 2015 · Dental Research Journal
Background: The aim of this study was to evaluate and compare the in vitro biofilm forming capacity of Enterococcus faecalis on Gutta-percha points disinfected with four disinfectants. Materials and Methods: A total of 50 Gutta-percha points used in this study were divided into four test groups based on disinfectant (5.25% sodium hypochlorite, 2% chlorhexidine gluconate, 20% neem, 13% benzalkonium chloride [BAK]), and one control group. The Gutta-percha points were initially treated with corresponding disinfectants followed by anaerobic incubation in Brain Heart Infusion broth suspended with h
View details →DOI: 10.4103/1735-3327.161446 Negative / Null Result ReportOpen accessMedicine (General)
Fatemeh Zanganeh, Amir Jalali, Hamid Galehdari et al. · 2014 · Iranian South Medical Journal
Background: Cytochrome P450 2E1 (CYP2E1) is a main enzyme which plays a major role in activating and detoxifying many xenobiotics, carcinogens and drugs. Available studies suggest that CYP2E1 single nucleotide polymorphisms (SNPs) are involved in the risk of developing certain cancers after exposure to carcinogens. The purpose of the present study was to assess genotype and allele frequencies of polymorphic CYP2E1*5B in the Iranian population. Material and Methods: This study was performed on 200 healthy individuals (female: 100, male: 100) in medical laboratories of Ahvaz during 2011. The CYP
Negative / Null Result ReportOpen accessVeterinary medicine
Sladojević Ž., Kasagić D., Kukolj B. et al. · 2013 · Veterinarski Glasnik
The objective of this work was to investigate the influence of housing conditions, number of farrowing and number of pigs in litter on weight loss in sows during lactation. The experiment included 60 sows, half breed developed by cross breeding of Big Yorkshire and Swedish Landrace in lactation. Body weight of the sows (kg) was determined 2nd, 7th, 14th, 21st and 28th day after farrowing. On the basis of the obtained values, there was calculated the difference in body weight between two consecutive investigation periods. The sows were divided into two groups and held in different housing condi
View details →DOI: 10.2298/vetgl1306337s Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities
Asmaa Al-suhimi · 2023 · مجلة جامعة الأنبار للعلوم الإنسانية
The current study aimed to design a counseling program based on gratitude for the development of psychological well-being, verify the effectiveness of this program and identify the continuity of its impact through the results of follow-up measurement after a month of its application. An intentional sample of (24) female students from the College of Education at King Khalid University, were randomly divided into two groups, a control, and an experimental group, each group consisted of 12 students, and the research tools used to measure the psychological well-being of university students Prepare
View details →DOI: 10.37653/juah.2023.138251.1158 Negative / Null Result ReportOpen accessArctic medicine. Tropical medicine
Emanuelle Santos de Carvalho Cardoso, Bruna Laís Santos de Jesus, Luciano Gama da Silva Gomes et al. · 2015 · Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Although urine is considered the gold-standard material for the detection of congenital cytomegalovirus (CMV) infection, it can be difficult to obtain in newborns. The aim of this study was to compare the efficiency of detection of congenital CMV infection in saliva and urine samples. METHODS: One thousand newborns were included in the study. Congenital cytomegalovirus deoxyribonucleic acid (DNA) was detected by polymerase chain reaction (PCR). RESULTS: Saliva samples were obtained from all the newborns, whereas urine collection was successful in only 333 cases. There was no stat
View details →DOI: 10.1590/0037-8682-0200-2014 Negative / Null Result ReportOpen accessSurgery
Cláudio de Saboya David, Alberto Goldenberg · 2018 · Acta Cirúrgica Brasileira
Abstract Purpose: To evaluate the behavior of arterial circulation and testicular volume in patients submitted to conventional inguinal hernia repair without the use of a synthetic prosthesis to reinforce the posterior wall. Methods: A prospective observational clinical trial was performed on 26 male patients with unilateral inguinal hernia types I and II by the Nyhus classification, who underwent surgical correction using the modified Bassini technique. Bilateral Doppler ultrasonography was performed preoperatively, at the third and at the sixth postoperative month. The studied variables were
View details →DOI: 10.1590/s0102-865020180030000009 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Somendra Bansal, Ketankumar G Rupala, Prasun Ghosh et al. · 2021 · Indian Journal of Urology
Introduction: The end-stage renal disease (ESRD) population is increasing worldwide and organ shortage is an important issue. The disparity between the availability of organs and waitlisted patients for transplants has forced many transplant centers across the world to use marginal kidney donors. We assess and compare postoperative estimated glomerular filtration rate (eGFR) in patients who received a graft from marginal renal donor (MRD) versus those who received a graft from standard renal donor (SRD). Methods: A total of 214 patients with ESRD underwent open live donor renal allografting fr
View details →DOI: 10.4103/iju.iju_32_21 Negative / Null Result ReportOpen accessMechanics of engineering. Applied mechanics
Atefeh Karimzadeh, Majid R. Ayatollahi, A.R. Bushroa · Latin American Journal of Solids and Structures
Abstract The purpose of this study was to investigate the effects of shade and material type and shape in dental polymer composites on the hardness and shrinkage stress of bulk and two-layered restoration systems. For this purpose, some bulk and layered specimens from three different shades of dental materials were prepared and light-cured. The experiments were carried out on three types of materials: conventional restorative composite, nanohybrid composite and nanocomposite. Micro-indentation experiment was performed on the bulk and also on each layer of layered restoration specimens using a
View details →DOI: 10.1590/1679-78252562 Null DatasetOpen accessEngineering (General). Civil engineering (General)
Chairul Salam M., Maharani Rindu Widara, Ign Mahendradewa Adam et al. · 2026 · Journal of Engineering and Applied Science
Abstract Rock fragmentation is a key determinant of downstream excavation performance in surface mining operations. Among blasting design parameters, stemming depth governs explosive energy confinement; however, its field-scale influence on fragmentation quality and excavation efficiency remains insufficiently quantified. This study experimentally investigates the effect of two stemming depths (3 m and 4 m) on rock fragmentation characteristics and excavator cycle time through controlled field blasting trials conducted in a hard sandstone formation. All blasts were executed using identical dri
View details →DOI: 10.1186/s44147-026-00920-z Negative / Null Result ReportOpen accessSpecial aspects of education
Houry Debra, Green Steven, Callaham Michael · 2012 · BMC Medical Education
Abstract Background Prior efforts to train medical journal peer reviewers have not improved subsequent review quality, although such interventions were general and brief. We hypothesized that a manuscript-specific and more extended intervention pairing new reviewers with high-quality senior reviewers as mentors would improve subsequent review quality. Methods Over a four-year period we randomly assigned all new reviewers for Annals of Emergency Medicine to receive our standard written informational materials alone, or these materials plus a new mentoring intervention. For this program we paire
View details →DOI: 10.1186/1472-6920-12-83 Negative / Null Result ReportOpen accessNursing
Maryam Ahmadinezhad, Marzieh Kargar, Fatemeh Vizeshfar et al. · 2017 · Iranian Journal of Nursing and Midwifery Research
Background: Postmenopausal women experience a variety of symptoms, among which sleep disorder is one of the most common problems. Acupressure and Pilates exercise programs are effective nonpharmaceutical treatments which can improve sleep quality. In the present study, we aimed to compare the effects of acupressure and Pilates-based exercises on the sleep quality of postmenopausal women referred to medical clinics. Materials and Methods: In this single-blinded randomized controlled clinical trial, we recruited 108 women aged 40–60 years who were randomly assigned into one control and two inter
View details →DOI: 10.4103/1735-9066.205954 Negative / Null Result ReportOpen accessMedicine
Amudha Jayanthi Anand, Mei Chien Chua, Siok Hong Khoo et al. · 2017 · Proceedings of Singapore Healthcare
Introduction: Extended hospitalization of low birth weight infants increases risk of medical and psychosocial complications. Our aim was to reduce the length of hospitalization and assess safety and cost savings of discharging infants at a weight of 1900 g instead of 2000 g, as has been the practice. Methods: This is a single-centre, nurse led quality improvement project done at a tertiary neonatal unit in Singapore with primary outcome of reducing average length of stay in selected low birth weight infants. In phase 1, infants with birth weight between 1000 and 1700 g were discharged at 1900
View details →DOI: 10.1177/2010105816676827 Failed Experiment ReportOpen accessDiseases of the blood and blood-forming organs
Pedro Henrique Prata, Dirk-Jan Eikema, Brian Piepenbroek et al. · 2025 · Haematologica
Aplastic anemia (AA) transformation into myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) is associated with a dismal prognosis. Hematopoietic stem cell transplant offers the sole possibility of cure, but data on long-term survival are scarce. We retrospectively analyzed 270 patients transplanted for MDS, AML, or an isolated cytogenetic abnormality after a diagnosis of AA or paroxysmal nocturnal hemoglobinuria reported to the EBMT. The median age at transplantation was 39 years. The 5-year overall survival (OS) rate was 64%, unaffected by chromosome 7 abnormalities, age at trans
View details →DOI: 10.3324/haematol.2024.287205 Negative / Null Result ReportOpen accessMedicine (General)
Mori N, Kobayashi A, Yokogawa H et al. · 2025 · International Medical Case Reports Journal
Natsuko Mori, Akira Kobayashi, Hideaki Yokogawa, Tomomi Higashide Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanCorrespondence: Akira Kobayashi, Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan, Tel +81-76-265-2403, Fax +81-76-222-9660, Email eyekoba@gmail.comPurpose: To describe two corneal adverse events temporally associated with anti–tumor necrosis factor-α (TNF-α) therapy—one with severe fibrovascular pannus and another with epithelial keratopath
Negative / Null Result ReportOpen accessSurgery
Takatsugu Fujii, Shigeo Toda, Yuki Nishihara et al. · 2020 · Surgical Case Reports
Abstract Background Ischemic colitis can occur after colectomy and is sometimes difficult to treat. We report 4 cases of refractory, delayed onset, regional congestive colitis occurring on the anal side of the anastomosis after laparoscopic left hemicolectomy. Case presentation A total of 191 patients underwent surgery for left colon cancer (transverse, descending, and sigmoid colon cancer) at our hospital from January 2012 to December 2017. During the procedures, the left colic artery (LCA) or sigmoid colic artery (SA) was dissected, the superior rectal artery (SRA) was preserved, and the inf
View details →DOI: 10.1186/s40792-020-00919-5 Negative / Null Result ReportOpen accessPsychology
Barrotul Jazilah · 2020
The aim of this research was to explore burnout, work engagement, and job demand among debt collector workers. The total available population of employees (N= 32) Consumer Collection and Remedial Unit Bank Tabungan Negara Cabang Surabaya…
View details →DOI: 10.26740/jim.v8n3.p1038-1049 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Pylväläinen J, Talala K, Murtola T et al. · 2019 · Clinical Epidemiology
Juho Pylväläinen,1–3 Kirsi Talala,4 Teemu Murtola,5–7 Kimmo Taari,8 Jani Raitanen,1,9 Teuvo L Tammela,6 Anssi Auvinen1 1Tampere University, Faculty of Social Sciences (Health Sciences), Tampere, Finland; 2Helsinki University, Faculty of Medicine, Department of Diagnostics and Therapeutics, Helsinki, Finland; 3Helsinki University Central Hospital, Medical Imaging Center, Helsinki, Finland; 4Cancer Society of Finland, Finnish Cancer Registry, Mass Screening Registry, Helsinki, Finland; 5Tampere University, Faculty of Medicine and Health Technology, Prostate Cancer Research
Negative / Null Result ReportOpen accessSports medicine
Phob Ganokroj MD, Bradley W. Fossum BA, Justin Hollenbeck MSc et al. · 2023 · Orthopaedic Journal of Sports Medicine
Background: Segmental medial meniscal allograft transplantation (MAT) has been shown to restore knee biomechanics; however, stable fixation of the transplantation is critical to avoid extrusion and maximize healing. Purpose: To evaluate the degree of meniscal extrusion and biomechanical function of segmental medial MAT performed with meniscocapsular sutures versus repair augmentation with knotless suture anchors. Study Design: Controlled laboratory study. Methods: Segmental midbody medial meniscectomy and subsequent segmental medial MAT were performed on 10 fresh-frozen cadaveric knees. The kn
View details →DOI: 10.1177/23259671231182978 Negative / Null Result ReportOpen accessDairy processing. Dairy products
Camélia Marchand, Isabelle Royer, Rachel Gervais et al. · 2024 · Journal of Dairy Science
ABSTRACT: Most trace minerals (TM) are fed above dairy cow requirements in commercial herds but their fate and effects on dairy cows have not been well documented. In this study, we evaluated the effects of feeding short-term sulfate TM above recommendations on apparent total-tract digestibility of nutrients, rumen fermentation characteristics, serum concentrations, and milk yield and composition, as well as milk, fecal, and urinary TM excretion in midlactation dairy cows. Eight multiparous Holstein cows with an average body weight (± SD) of 684 ± 29 kg at 82 ± 10 DIM in a quadruple 2 × 2 cros
View details →DOI: 10.3168/jds.2024-24761 Negative / Null Result ReportOpen accessMedicine
Ahmad-Ali Asadi-Noghabi, Mohammad Gholizadeh, Mitra Zolfaghari et al. · 2015 · Oman Medical Journal
Objectives: The diagnosis of pain in patients with low consciousness is a major challenge in the intensive care unit (ICU). Therefore, the use of behavioral tools for pain assessment could be an effective tool to manage pain in this group of patients. The aim of this study was to determine the effects on pain management by nurses using a critical care pain observational tool in patients with a decreased level of consciousness. Methods: Our research used a before and after design to evaluate the ability of nurses to manage pain in patients with low consciousness. A total of 106 ICU nurses were
View details →DOI: 10.5001/omj.2015.55 Negative / Null Result ReportOpen accessDentistry
Alvaro Carvajal-Flórez, Diana María Barbosa-Lis, Oscar Arturo Zapata-Noreña et al. · 2016 · Dental Press Journal of Orthodontics
ABSTRACT Objective: To evaluate the results of a finishing protocol implemented in patients treated in the Orthodontics graduate program at Universidad de Antioquia. Evaluation was carried out by means of the criteria set by the Objective Grading System (OGS) of the American Board of Orthodontics (ABO). Methods: Cast models and panoramic radiographs of 34 patients were evaluated. The intervention group (IG) consisted of 17 patients (19.88 ± 4.4 years old) treated under a finishing protocol. This protocol included training in finishing, application of a finishing guide, brackets repositioning a
View details →DOI: 10.1590/2177-6709.21.2.088-094.oar Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Shoji Kawashima, RCIP-Nagoya Study Group, Noriyuki Matsukawa · 2022 · BMC Neurology
Abstract Background Mild cognitive impairment in Parkinson’s disease (PD-MCI) is associated with an increased risk of cognitive decline. PD-MCI is characterized by impairments in executive function and visuospatial recognition. The visuospatial n-back test is useful for assessing both domains. The 0-back test reflects visuospatial recognition, while the 1-back and 2-back tests reflect working memory. Cholinesterase inhibitors are effective in the treatment of PD-MCI and dementia in PD (PDD). Although some studies have reported the efficacy of memantine for PDD, the therapeutic efficacy of mema
View details →DOI: 10.1186/s12883-022-02699-x Failed Experiment ReportOpen access
Sanne Everling, F. Johansson · 2022 · Ecological Entomology
Studies on interaction between species are needed to observe and predict the effects of climate change on species distributions. Here we studied intra‐ and interspecific competition and behaviour in larvae of a native and a northward…
View details →DOI: 10.1111/een.13130 Negative / Null Result ReportOpen accessOphthalmology
Hao Jiang, Chao Xue, Yanlin Gao et al. · 2022 · Journal of Ophthalmology
Purpose. This study aimed to assess the application of a foldable capsular vitreous body (FCVB) in the treatment of severe ocular trauma and silicone oil (SO) dependent eyes. Methods. A retrospective analysis was performed on the clinical application of FCVB in the treatment of severe ocular trauma and SO dependent eyes. The results of best-corrected visual acuity and intraocular pressure (IOP) evaluation, B-scan ultrasonography or color Doppler ultrasonography, ultrasound biomicroscopy, and anterior segment photography were recorded during follow-up. A paired t-test was used to compare the di
View details →DOI: 10.1155/2022/3608162 Negative / Null Result ReportOpen accessMicrobiology
Mieko Higuchi‐Takeuchi, Kumiko Morisaki, Keiji Numata · 2020 · MicrobiologyOpen
Abstract Marine purple photosynthetic bacteria are ideal organisms for the production of useful materials at reduced costs and contributing to a sustainable society because they can utilize sunlight, seawater, and components of air, including carbon dioxide and nitrogen gases, for their growth. However, conjugation is the only applicable method for the transformation of marine purple photosynthetic bacteria so far. Here, we examined a calcium chloride‐mediated method for the transformation of marine purple photosynthetic bacteria. Plasmid DNAs containing the kanamycin resistance gene were succ
View details →DOI: 10.1002/mbo3.953 Negative / Null Result ReportOpen accessAnimal culture
J. Michiels, J. Missotten, A. Ovyn et al. · 2012 · Czech Journal of Animal Science
Thymol's antimicrobial properties urged researchers to study its effect on animal performance and intestinal health in pigs. However, thymol has the characteristic sharp odor of thyme and a bitter, aromatic, and sometimes burning sensation which may elicit feeding aversions. The objectives in the current study were: (1) to determine the effect of dose of thymol and camphor on palatability and (2) to test the hypothesis that supplemental flavours or camphor, the latter as a known Transient Receptor Potential A1 blocker, could mitigate feed avoidance caused by thymol. Two analogous choice-feedin
View details →DOI: 10.17221/5133-cjas Negative / Null Result ReportOpen accessArctic medicine. Tropical medicine
María Ailén Natale, Todd Minning, María Cecilia Albareda et al. · 2021 · PLoS Neglected Tropical Diseases
In chronic Chagas disease, Trypanosoma cruzi-specific T-cell function decreases over time, and alterations in the homeostatic IL-7/IL-7R axis are evident, consistent with a process of immune exhaustion. IL-27 is an important immunoregulatory cytokine that shares T-cell signaling with IL-7 and other cytokines of the IL-12 family and might be involved in the transcriptional regulation of T-cell function. Here, we evaluated the expression and function of IL-27R in antigen-experienced T cells from subjects with chronic Chagas disease and assessed whether in vitro treatment with IL-27 and IL-7 migh
View details →DOI: 10.1371/journal.pntd.0009473 Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Sagar B. Dugani, MD, PhD, MPH, Shangwe A. Kiliaki, CNP, DNP, Megan L. Nielsen, MSN, CNP et al. · 2023 · Mayo Clinic Proceedings: Digital Health
Objective: To determine whether a postdischarge video visit with patients, conducted by hospital medicine advanced practice providers, improves adherence to hospital discharge recommendations. Patients and Methods: We conducted a single-institution 2-site randomized clinical trial with 1:1 assignment to intervention vs control, with enrollment from August 10, 2020, to June 23, 2022. Hospital medicine patients discharged home or to an assisted living facility were randomized to a video visit 2-5 days postdischarge in addition to usual care (intervention) vs usual care (control). During the vide
View details →DOI: 10.1016/j.mcpdig.2023.06.006 