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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21720 results · page 417 of 724

Negative / Null Result ReportMedicine

MRI-based volumetric and histogram analysis of parotid and submandibular glands in hypertensive patients: a retrospective study.

Kotanlı, Yılmaz, Dogan · 2026 · BMC oral health

The aim of this retrospective study is to evaluate the volumetric and histogram-based characteristics of the parotid and submandibular salivary glands in patients with hypertension compared with healthy controls. Magnetic Resonance images…

View details →DOI: 10.1186/s12903-026-08727-3
Negative / Null Result ReportMedicine

Revision rate and postoperative volume development of chronic subdural hematomas after burr hole craniotomy in combination with tranexamic acid vs. surgery alone - a single-center propensity score-matched analysis.

Scheer, Witte, Guenzerodt et al. · 2026 · BMC neurology

Chronic subdural hematoma (cSDH) is a common intracranial hemorrhage in elderly patients and is associated with substantial postoperative recurrence rates. Tranexamic acid (TXA) has been proposed as an adjuvant therapy to reduce recurrence…

View details →DOI: 10.1186/s12883-026-05003-3
Negative / Null Result ReportMedicine

Paraesophageal hernia repair is associated with similar safety and efficacy results in octogenarians as compared to younger patients.

Barekatain, Simon, Lyons et al. · 2026 · Surgical endoscopy

National database studies suggest elective paraesophageal hernia (PEH) repair in octogenarians is safe but provide limited detail on operative strategy and long-term symptom outcomes. We evaluated perioperative outcomes, operative…

View details →DOI: 10.1007/s00464-026-12944-w
Negative / Null Result ReportMedicine

Cryoprecipitate utilization in the neonatal intensive care unit: a single-center review.

Stoeckel, Soule-Albridge, Feldman et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association

Significant variability exists in the indications for and dosing of cryoprecipitate transfusions. We examined cryoprecipitate transfusions in neonates with a focus on indications, dosing, and the incidence of multi-donor exposure. In this…

View details →DOI: 10.1038/s41372-026-02740-8
Negative / Null Result ReportMedicine

Clinical correlates of ocular dominance in post-facial paralysis synkinesis.

Kapur, Henry, Lee et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS

We aimed to explore the relationship between ocular dominance and synkinesis severity. Through phone interviews and a web-based survey, patients were asked to test their ocular dominance via the Miles test. Additionally, patients were…

View details →DOI: 10.1016/j.bjps.2026.05.041
Negative / Null Result ReportMedicine

Single anastomosis duodeno-ileal bypass with sleeve gastrectomy in the United States: has increased volume impacted safety?

Ballato, Shenoy, Le Gardeur De Tilly et al. · 2026 · Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Originally described in 2007, the single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) was only endorsed by the American Society for Metabolic and Bariatric Surgery in 2020. Since then, the procedure has grown…

View details →DOI: 10.1016/j.soard.2026.05.011
Negative / Null Result ReportMedicine

Novel Simulation-based Awake Fiberoptic Intubation Curriculum: Pilot Study.

Haas, Fredette, Murphy et al. · 2026 · The western journal of emergency medicine

Awake fiberoptic intubation is a critical skill of emergency physicians in scenarios where rapid sequence intubation may be impossible or catastrophic. While the equipment to perform awake fiberoptic intubation has become more readily…

View details →DOI: 10.5811/westjem.50778
Negative / Null Result ReportMedicine

Difference in outcomes between right and left posterior descending artery percutaneous coronary intervention: an Australian statewide registry analysis.

Rahman Zahin, Batchelor, Brennan et al. · 2026 · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

Percutaneous coronary intervention (PCI) is an important treatment for coronary artery disease, and coronary dominance may influence procedural risk. PCI to a left-sided posterior descending artery (L-PDA) occurs in the setting of…

View details →DOI: 10.1186/s43044-026-00755-2
Negative / Null Result ReportMedicine

Choledochoduodenostomy versus transpapillary stent by endoscopic retrograde cholangiopancreatography for preoperative biliary drainage before pancreatoduodenectomy: a French multicenter retrospective cohort study.

Belfil, Diai, Gonzalez et al. · 2026 · Surgical endoscopy

 Few studies have compared the different types of endoscopic biliary drainage, particularly endoscopic retrograde cholangiopancreatography (ERCP) versus Endoscopic ultrasound guided-Choledochoduodenostomy (EUS-CD), for jaundice caused…

View details →DOI: 10.1007/s00464-026-12722-8
Negative / Null Result ReportMedicine

Prospective Methodology Results in Higher Rates of Reported Complications Following Pediatric ACL Reconstruction.

Martin, Ellis, Agonias et al. · 2026 · Journal of pediatric orthopedics

The incidence of pediatric anterior cruciate ligament reconstructions (ACLR) has drastically increased over the last 20 years. Previous studies have sought to characterize postoperative complications, but few have utilized a prospective,…

View details →DOI: 10.1097/bpo.0000000000003359
Negative / Null Result ReportMedicine

The Effect of Guided Imagery and Music with Sasando Music on Anxiety among Ischemic Stroke.

Mbau, Handayani, Kusumaningrum · 2026 · Iranian journal of nursing and midwifery research

Guided Imagery and Music (GIM) interventions reduced the anxiety in many clinical settings. Traditional music pictures the emotion of specific culture. No interventional study was found in reducing anxiety among ischemic stroke patients…

View details →DOI: 10.4103/ijnmr.ijnmr_23_23
Negative / Null Result ReportMedicine

Multiple Genetic Origins of Non-Native, Self-Sustaining Rainbow Trout Oncorhynchus mykiss in Streams in Baden-Württemberg, Germany.

Koene, Jacobs, Bartolin et al. · 2026 · Evolutionary applications

Introduced in the late 19th Century, Oncorhynchus mykiss (rainbow trout) has been stocked historically in streams throughout Baden-Württemberg, Germany, and some populations have become self-sustaining with unclear impact on native…

View details →DOI: 10.1111/eva.70271
Negative / Null Result ReportMedicine

Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis.

Wu, Zhang, He et al. · 2026 · Frontiers in cellular and infection microbiology

Brucellosis remains an important public health problem globally. Rapid and accurate diagnosis is crucial for the treatment of brucellosis. However, current diagnostic methods for brucellosis are limited, posing significant clinical…

View details →DOI: 10.3389/fcimb.2026.1806232
Negative / Null Result ReportMedicine

Similar secondary patellar resurfacing but higher tibial revision risk with posterior stabilized versus medial pivot total knee arthroplasty: A registry analysis.

Pflüger, Pedrazzini, Jud et al. · 2026 · Journal of experimental orthopaedics

Patellar complications are among the most frequent causes of revision after primary total knee arthroplasty (TKA). The primary study objective is to compare the rate of secondary patellar resurfacing between medial pivot (MP) and posterior…

View details →DOI: 10.1002/jeo2.70751
Negative / Null Result ReportMedicine

Long-Term Outcomes After Catheter-Directed Thrombolysis or Mechanical Thrombectomy in Intermediate-High-Risk Pulmonary Embolism: A Propensity-Matched Analysis From a TriNetX Database.

Giorgi, Bertoletti, Luis et al. · 2026 · Pulmonary circulation

Catheter-directed thrombolysis (CDL) and mechanical thrombectomy (MT) are increasingly used for intermediate-high-risk pulmonary embolism (PE), yet comparative long-term outcomes remain uncertain. We aimed to compare the effectiveness and…

View details →DOI: 10.1002/pul2.70329
Negative / Null Result ReportMedicine

Endoscopic Versus Open Carpal Tunnel Release in Obese and Nonobese Patients.

Salib, Sanchez, Diatta et al. · 2026 · Journal of hand surgery global online

This study compared postoperative complications and revision rates following endoscopic versus open carpal tunnel release (CTR) in obese and nonobese patients. A 2010-2022 national administrative database was queried to identify adults…

View details →DOI: 10.1016/j.jhsg.2026.101053
Failed Experiment ReportMedicine

Survival Outcomes in Early Onset Appendiceal Adenocarcinoma (EOAA).

Gujarathi, Belmont, Rodman et al. · 2026 · Annals of surgical oncology

The incidence of early onset (age&#x2009;<&#x2009;50 years at diagnosis) appendiceal adenocarcinoma (EOAA) is rising alarmingly. Reported data on etiology, treatment, and outcomes is scarce. In this study, we report clinical outcomes for…

View details →DOI: 10.1245/s10434-026-19855-z
Failed Experiment ReportMedicine

Age-dependent alterations in anterior cingulate excitation-inhibition balance in major depressive disorder revealed by 7-Tesla magnetic resonance spectroscopy.

Yoshihara, Suwa, Kubota et al. · 2026 · NeuroImage. Clinical

Altered excitation-inhibition (E/I) balance has been implicated in the pathophysiology of major depressive disorder (MDD), but previous magnetic resonance spectroscopy (MRS) findings have been inconsistent, partly due to methodological…

View details →DOI: 10.1016/j.nicl.2026.104018