Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Pei Wang, Pei Wang, Zhizhong Dong et al. · 2024 · Frontiers in Endocrinology
BackgroundActive surveillance has been an option for patients with low-risk papillary thyroid carcinoma (PTC). However, whether delayed surgery leads to an increased risk of local tumor metastasis remain unclear. We sought to investigate the impact of observation time on central lymph node metastasis (CLNM) and multifocal disease in patients with low-risk PTC.MethodsPatients who were diagnosed with asymptomatic low-risk PTC, and with a pathological maximum tumor size ≤1.5 cm by were included. The patients were classified into observation group and immediate surgery group, and subgroup analyses
View details →DOI: 10.3389/fendo.2024.1349272 Negative / Null Result ReportOpen accessDentistry
Ada Njokanma, Olayinka Otuyemi, Kikelomo Kolawole · 2023 · Nigerian Dental Journal
Background: Digit sucking habit (DSH) generates functional forces that can influence craniofacial morphology. Although the dental effects have been widely reported, its influence on the masseter muscle thickness (MMT) and upper airway (UA) dimensions is not well known. Methods: Thirty (30) children selected from the orthodontic clinic (OAUTHC), with a DSH were matched with a group of 30 children without a DSH. Each group comprised of 16 males and 14 females. Ultrasonographic evaluation of the masseter muscle (MM) was performed to measure the left and right MMT in the relaxed and contracted sta
View details →DOI: 10.61172/ndj.v31i2.255 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
A. Guermazi, G. Kalsi, J. Niu et al. · 2017 · BMC Musculoskeletal Disorders
Abstract Background To determine effects of allogeneic human chondrocytes expressing TGF-β1 (TG-C) on structural progression of MRI features of knee osteoarthritis over a 1 year period. Methods This phase II randomized controlled trial of TG-C included patients with moderate to advanced osteoarthritis. Patients were randomized to receive an intraarticular 3:1 mixture of non-transduced allogeneic human chondrocytes and TG-C or placebo. 3 T MRI was acquired for all patients at baseline and follow-up (3, 6 and 12 months). MRIs were assessed using the WORMS system including cartilage damage, bone
View details →DOI: 10.1186/s12891-017-1830-8 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Hakan Demirci, Yildirim Cinar, Nazan Bilgel · 2021 · Psychiatry and Clinical Psychopharmacology
Background: The possible association between depressive symptoms and metabolic syndrome (MetS) has recently become an important topic of discussion. There is some limited and inconsistent evidence in the literature concerning whether or not depression and metabolic syndrome are associated. The aim of this study was to examine the association between depressive symptoms and metabolic syndrome. Methods: This is a cross-sectional community-based study. The setting is a family practice unit in an urban area which serves about 3,600 people. The participants were 250 individuals aged 18 and over, se
View details →DOI: 10.5350/kpb-bcp201121108 Negative / Null Result ReportOpen accessMedicine
Kričković Zoran, Simatović Milan, Lukić Darko et al. · 2020 · Scripta Medica
Background/Aim: Benign prostatic hyperplasia (BPH) is a very common disease in older men. BPH involves the presence of signs of hyperplasia of the stromal and epithelial elements in the prostate with consequent enlargement of its volume. The aim of this study is to analyse the frequency of typical complications in the treatment of patients with benign prostatic hyperplasia and the effect of medicamentous treatment. Method: Patients diagnosed BPH were included in the prospective, one-year study. They were divided into 2 groups. The first group (30 patients) consisted of those ones, whose prosta
Negative / Null Result ReportOpen accessScience (General)
Nury Tatiana Jiménez, Juan Carlos Munévar, José Manuel González et al. · 2018 · Heliyon
Three-dimensional-porous scaffolds of bone graft substitutes play a critical role in both cell targeting and transplantation strategies. These scaffolds provide surfaces that facilitate the response of stem cells related to attachment, survival, migration, proliferation, and differentiation. Objective: The aim of this study was to evaluate the in vitro behavior of human dental pulp mesenchymal stem cells cultured on scaffolds of polylactic/polyglycolic acid with and without hydroxyapatite. Method: We performed an in vitro experimental study using dental pulp stem cells obtained from samples of
View details →DOI: 10.1016/j.heliyon.2018.e00775 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Md Khairul Islam, Ivan Lozada Lawag, Kathryn J. Green et al. · 2022 · Current Research in Food Science
This study reports on the analysis of eleven Jarrah (Eucalyptus marginata) honeys, of which nearly half (n = 5) were re-classified as Blackbutt (E. patens) honey on the grounds of the predominant flower pollen identified by melissopalynology. Based on a comprehensive analysis of the honeys' physico- and phytochemical characteristics and antioxidant activity data, taking into account pH, electrical conductivity, refractive index and Brix values as well as moisture content, individual fructose and glucose content and derived fructose to glucose ratio alongside total phenolic content and antioxid
View details →DOI: 10.1016/j.crfs.2022.02.014 Negative / Null Result ReportOpen accessBiochemistry
Carlotta Peticone, David De Silva Thompson, Nikolay Dimov et al. · 2020 · Journal of Tissue Engineering
Using microspherical scaffolds as building blocks to repair bone defects of specific size and shape has been proposed as a tissue engineering strategy. Here, phosphate glass (PG) microcarriers doped with 5 mol % TiO 2 and either 0 mol % CoO (CoO 0%) or 2 mol % CoO (CoO 2%) were investigated for their ability to support osteogenic and vascular responses of human mesenchymal stem cells (hMSCs). Together with standard culture techniques, cell-material interactions were studied using a novel perfusion microfluidic bioreactor that enabled cell culture on microspheres, along with automated processin
View details →DOI: 10.1177/2041731420954712 Negative / Null Result ReportOpen accessTechnology
Jolanta Grochowska, Renata Tandyrak · 2021 · Applied Sciences
A study was carried out in the Kartuzy lake complex, which has been a receiver of raw domestic sewage since the 1950s. In 2018, the city’s sewage system of Kartuzy was modernized. An analysis of the water quality prior to the modernization of the sewage system revealed that the total phosphorus (TP) load that was introduced to the individual lakes from external sources substantially exceeded the dangerous load concentration (defined by Vollenweider) that causes accelerated eutrophication. The annual TP load introduced to the analyzed lakes in 2017 exceeded the critical load by 200% (Mielenko)
View details →DOI: 10.3390/app11030974 Negative / Null Result ReportOpen accessMedicine
Rokaya D, Al Jaghsi A, Masri M et al. · 2026 · Frontiers in dental medicine
Objectives This study aimed to investigate the accuracy of two intraoral scanners at different post space preparation depths and widths for CAD/CAM fabricated post and core fabrication. Methods A total of 36 extracted anterior teeth were…
View details →DOI: 10.3389/fdmed.2026.1691514 Negative / Null Result ReportMedicine
Malvandi H, Shamabadi MH, Vaezi I · 2026 · Bulletin of environmental contamination and toxicology
In the present study, thirteen urban bird species were used as bioindicators to monitor metal concentrations in the metropolis of Mashhad. The concentrations of lead (Pb), zinc (Zn), and copper (Cu) ranged from 0.004 to 0.073, 0.750 to…
View details →DOI: 10.1007/s00128-026-04265-4 Negative / Null Result ReportOpen accessMedicine
Zaharovs V, Pilmane M · 2026 · Journal of molecular histology
The anti-apoptotic genes DAD-1 and HAX-1 and the pro-apoptotic GZMB gene have a significant role in the regulation of apoptosis in heart tissue. However, investigation into these genes and their proteins in the pathogenesis of…
View details →DOI: 10.1007/s10735-026-10849-5 Negative / Null Result ReportMedicine
Clukey J, Locascio J, Semler J et al. · 2026 · Journal of clinical gastroenterology
Goals We aimed to evaluate the efficacy and safety of IFT for the treatment of CC in a pilot randomized controlled trial (RCT). Background Subjects with refractory chronic constipation (CC) have limited treatment options. Interferential…
View details →DOI: 10.1097/mcg.0000000000002405 Negative / Null Result ReportOpen accessMedicine
Vatan A, Karabay O, Moralı H et al. · 2026 · BMC infectious diseases
Background Tenofovir alafenamide (TAF) is widely used in antiretroviral therapy due to its improved renal and bone safety compared to tenofovir disoproxil fumarate (TDF). However, concerns remain regarding its potential metabolic effects…
View details →DOI: 10.1186/s12879-026-13377-5 Negative / Null Result ReportMedicine
Shikama T, Otaki Y, Kinoshita D et al. · 2026 · Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
Objective Nodular calcifications occupying the lumen in the femoropopliteal artery, known as "Black Rock (BR)" lesions, are associated with poor patency. We focused on the drug-coated balloon (DCB) and examined whether the impact of final…
View details →DOI: 10.1177/15266028261434775 Negative / Null Result ReportOpen accessMedicine
Wu G, Ou X, Zou M et al. · 2026 · Journal of cancer research and clinical oncology
OBJECTIVE: This study aimed to compare the outcomes of no-touch radiofrequency ablation (NT-RFA) and conventional RFA (C-RFA) in the treatment of solitary recurrent hepatocellular carcinoma (rHCC) ≤ 3 cm. METHODS: 255 patients with rHCC…
View details →DOI: 10.1007/s00432-026-06453-5 Negative / Null Result ReportMedicine
Mostamand S, Merchant Q, Ji Y et al. · 2026 · Neurogastroenterology and motility
Background Anorectal manometry (ARM) is a commonly performed motility test in pediatrics. Currently, adult ARM normative data are extrapolated to pediatric assessments due to few validated pediatric studies. We share a single center…
View details →DOI: 10.1111/nmo.70371 Negative / Null Result ReportMedicine
Salık M, Bakır EP · 2026 · Journal of functional biomaterials
Aim: The aim of this study was to comparatively evaluate the shear bond strengths between different calcium silicate-based biomaterials and glass ionomer-based restorative materials. Materials and Methods: In this in vitro study, a total…
View details →DOI: 10.3390/jfb17060309 Negative / Null Result ReportMedicine
Liang H, Gui Y, Lv K et al. · 2026 · Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Objective To compare the imaging efficacy and patient tolerability of a novel cellulose-based oral contrast agent with a conventional starch-based agent in gastric contrast-enhanced ultrasound,thus providing evidence-based support for…
View details →DOI: 10.3881/j.issn.1000-503x.17161 Negative / Null Result Report
SECK AB, DOGBE KA, AVOUBA F–GN · 2026 · Preprint
Abstract Institutions are widely recognized as key factors in attracting foreign direct investment (FDI) and fostering economic development in host countries. However, there is growing evidence that natural resources may also play a…
View details →DOI: 10.21203/rs.3.rs-9635942/v1 Negative / Null Result ReportMedicine
Šostakaitė G, Jauniškytė M, Budrys D et al. · 2026 · Nutrients
Background : Critically ill patients experience rapid muscle wasting during their ICU stay. Ultrasound (US) and bioelectrical impedance analysis (BIA) are widely used to assess muscle mass; however, their accuracy may be affected by fluid…
View details →DOI: 10.3390/nu18122019 Negative / Null Result ReportOpen accessMedicine
Bellew S, Tjiattas-Saleski L, Butz D et al. · 2026 · The western journal of emergency medicine
Introduction Computed tomography (CT) is an essential diagnostic tool for evaluating emergency department (ED) patients. Between 15-20% of patients who present to the ED in the United States (US) undergo CT imaging. CT imaging with the use…
View details →DOI: 10.5811/westjem.62947 Negative / Null Result ReportMedicine
Murphy C, Baglioni M, Lepage OM et al. · 2026 · The Veterinary record
Background To our knowledge, the effect of sedation with romifidine on the grading of laryngeal function in horses has not been studied. Our objective was to examine the effects of romifidine on the grading of laryngeal function and the…
View details →DOI: 10.1002/vetr.70804 Negative / Null Result ReportMedicine
Liu H, Liu L, Zhao Z et al. · 2026 · Scientific reports
Psychological distress is a major public health issue with multisystemic effects, yet its multidimensional nature and specific links to urogenital disorders remain inadequately characterized due to methodological limitations of prior…
View details →DOI: 10.1038/s41598-026-58389-y Negative / Null Result ReportOpen accessMedicine
Mirzaei R, Soleimanzadeh A, Asri-Rezaei S · 2026 · Scientific reports
Dog semen conservation at cold temperatures (5 °C) is a valuable reproductive management tool, but it is bedeviled by issues of oxidative stress and mitochondrial damage that reduce sperm quality and viability. Urolithin A (UA), a natural…
View details →DOI: 10.1038/s41598-026-49089-8 Negative / Null Result ReportMedicine
Laffi A, Piras A, Meoni A et al. · 2026 · Biomedicines
Background: Exercise plays a crucial role in the prevention and management of type 2 diabetes. During self-motion, optic flow provides visual information about heading direction and influences postural control. This study investigated…
View details →DOI: 10.3390/biomedicines14061349 Negative / Null Result ReportOpen accessMedicine
Güngör ÖF, Ünal N, Paksoy Y · 2026 · Archives animal breeding
This study aimed to investigate the effects of pregnancy type, genotype, and parturition stage on sheep behavior. It also examined how pregnancy type and genotype influence labor characteristics. These evaluations were necessary because…
View details →DOI: 10.5194/aab-69-289-2026 Negative / Null Result Report
Pramitra B, Al Musadieq M, Afrianty TW et al. · 2026 · Preprint
Although digital transformation in port management has been widely discussed, previous studies have not extensively examined how organizational capabilities translate into performance through digital adoption at ports. This study addresses…
View details →DOI: 10.12688/f1000research.176261.3 Negative / Null Result ReportMedicine
Degli Antoni G, Gandolfi G, Soana MG · 2026 · Health policy (Amsterdam, Netherlands)
Background Financial anxiety has increased over the past decade, particularly among young people. While prior research has examined its determinants and consequences, coping strategies have been very poorly explored so far. Objective This…
View details →DOI: 10.1016/j.healthpol.2026.105669 Negative / Null Result ReportMedicine
Shen LL, Shi BB, Xiong WY et al. · 2026 · Sheng li xue bao : [Acta physiologica Sinica]
This study aims to investigate whether the reduction in early embryonic development due to repeated controlled ovarian stimulation (COS) is associated with the expression levels of enzymes related to aerobic glycolysis. A repeated COS…
View details →DOI: 10.13294/j.aps.2026.0026 