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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

AllReplication FailureNegative / Null Result ReportFailed Experiment ReportAbandoned HypothesisMethods Dead-EndShort NoteNull DatasetProtocol

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

By fieldMedicine 12,266Computer Science 751Biochemistry, Genetics and Molecular Biology 431Social Sciences 306Psychology 304Physics 280Neuroscience 254Economics, Econometrics and Finance 204Environmental Science 178Mathematics 159Engineering 145Agricultural and Biological Sciences 142

21314 results · page 397 of 711

Negative / Null Result ReportMedicine

Infant social withdrawal with parents and strangers-The role of parental sensitivity and depression.

Rudling, Stuart, Smith-Nielsen et al. · 2026 · The British journal of developmental psychology

Infant social withdrawal is an early indicator of infant distress linked to adverse socio-emotional development. We hypothesized that parental sensitivity moderates an association between parental depression (PPD) and infant social…

View details →DOI: 10.1111/bjdp.70054
Negative / Null Result ReportMedicine

Association between periodontal and geriatric health: a cross-sectional study.

Müller, Deschner, Mohr et al. · 2026 · Clinical oral investigations

This cross-sectional study investigated the association between periodontal status and geriatric health parameters, a relationship that has received little attention in research to date. The periodontal health of 51 geriatric patients was…

View details →DOI: 10.1007/s00784-026-06938-0
Negative / Null Result ReportMedicine

Diagnostic performance of computed tomography colonography following incomplete colonoscopy and its associated factors: A single-centre retrospective study.

Mohd Hayati, Abdul Wahid, Shamsidi et al. · 2026 · The Medical journal of Malaysia

Incomplete colonoscopy presents an important clinical challenge, as segments of the colon that are not visualised may contain significant pathology. Computed tomography colonography (CTC) provides a minimally invasive alternative for…

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Negative / Null Result ReportMedicine

A real-world data analysis of the impact of clonal hematopoiesis of indeterminate potential on therapeutic efficacy and adverse events of immune checkpoint inhibitors.

Fujita, Ishibashi, Aoyama et al. · 2026 · Cancer

Clonal hematopoiesis of indeterminate potential (CHIP) has been implicated in systemic inflammation. Although immune checkpoint inhibitors (ICIs) have transformed cancer care, their response rates remain modest, and some patients…

View details →DOI: 10.1002/cncr.70398
Negative / Null Result ReportMedicine

Impact of ABCB1 (rs1045642) polymorphism on antipsychotic-induced extrapyramidal symptoms in Egyptian patients with schizophrenia.

Ahmed, Moawad, Tarek et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

The ABCB1 polymorphisms may influence risperidone-induced extrapyramidal symptoms (EPS) in schizophrenia. This cross-sectional study examined the relationships among ABCB1 variants, clinical factors, and objective, subjective EPS in 150…

View details →DOI: 10.1016/j.fct.2026.116181
Negative / Null Result ReportMedicine

MRI-based classification of pes anserinus tendon variations and their clinical implications in non-traumatic knees.

Çavuş, Aktürk, Argalı Deniz et al. · 2026 · Folia morphologica

The pes anserinus (PA) is a morphologically variable structure whose in vivo tendon configurations remain incompletely characterized on routine MRI. This study aimed to define the typical tritendinous configuration of the PA, identify…

View details →DOI: 10.5603/fm.111983
Negative / Null Result ReportMedicine

An Observational Study on Impact of Interim Obturators in COVID-19-Associated Mucormycosis.

Chittamuru, Vengamma, Priya et al. · 2026 · Journal of maxillofacial and oral surgery

During the second wave of COVID-19 pandemic, there was surge in reporting of COVID-19-associated mucormycosis cases. Government of India declared rhino-orbito-cerebral mucormycosis as a notifiable disease. Managing this condition posed a…

View details →DOI: 10.1007/s12663-024-02120-9
Negative / Null Result ReportMedicine

Association Between Early Versus Delayed Outpatient Follow-Up After Hospital Discharge and Short-Term Healthcare Utilization Among ICU Survivors.

Oletu, Oladimeji, Osueni et al. · 2026 · Cureus

Intensive care unit (ICU) survivors experience high rates of healthcare utilization after hospital discharge, including readmissions and emergency department (ED) visits. Timely outpatient follow-up has been proposed to improve care…

View details →DOI: 10.7759/cureus.107746
Negative / Null Result ReportMedicine

Body fat percentage and factors associated with cholesterol levels among patients at healthy choice clinic in Kathmandu, Nepal: a cross-sectional study.

Adhikari, Karki, Samu · 2026 · BMC nutrition

The study of body composition and its correlation with lipid profiles are significant markers for the cardiovascular risk factors of the urban Nepali population. This study is an attempt to evaluate the percentage of body fat and determine…

View details →DOI: 10.1186/s40795-026-01378-1
Negative / Null Result ReportMedicine

Allergic Status, Long COVID, and Post-Restriction Respiratory Outcomes in Children: A Single-Center Questionnaire-Based Study.

Brindisi, Gori, Pignataro et al. · 2026 · Journal of clinical medicine

Background: The relationship between allergic status, SARS-CoV-2 infection, Long COVID, and post-restriction respiratory outcomes in children remains incompletely understood. This study aimed to explore the associations between allergic…

View details →DOI: 10.3390/jcm15103982
Negative / Null Result ReportMedicine

Emergence Angle, Marginal Bone Loss, and Radiographic Corticalization Around MIS Implants: A 5-Year Retrospective Study of Single, Splinted, and Bridge Restorations.

Wach, Kuta, Michcik et al. · 2026 · Journal of clinical medicine

Background/Objectives : Dental implants are a predictable treatment modality for missing teeth, and the crown emergence angle may affect peri-implant tissue health. This study evaluated the influence of crown emergence angle on marginal…

View details →DOI: 10.3390/jcm15103764
Negative / Null Result ReportMedicine

Prognostic Impact of PET/CT-Derived Sarcopenia in Metastatic Breast Cancer Treated with CDK4/6 Inhibitors.

Cebeci, Birsin, Jeral Evinç et al. · 2026 · Journal of clinical medicine

Objective: This study aimed to evaluate the prognostic significance of positron emission tomography/computed tomography (PET/CT)-derived sarcopenia in patients with hormone receptor-positive, HER2-negative metastatic breast cancer treated…

View details →DOI: 10.3390/jcm15103736
Negative / Null Result ReportMedicine

Dental Treatment Needs in Older Adults Undergoing Acute Geriatric Care: A Cross-Sectional Observational Study of Clinical Need and Patient-Reported Wish for Dental Treatment.

Werneburg, Schönenberg, Andernach et al. · 2026 · Journal of clinical medicine

Background/Objectives : Dental care is not routinely integrated into acute geriatric complex treatment, although older inpatients often present with substantial oral disease. This study assessed dental treatment needs, their relationship…

View details →DOI: 10.3390/jcm15103610
Negative / Null Result ReportMedicine

Reliability and patient-centered feasibility of the Gross Motor Function Measure in children diagnosed with central nervous system tumor.

Mantovani, Chagas, Horiquini-Barbosa · 2026 · Developmental neurorehabilitation

Children diagnosed with central nervous system (CNS) tumors frequently present with persistent motor impairments that compromise independence and participation. Although the Gross Motor Function Measure (GMFM-88) is widely used in…

View details →DOI: 10.1080/17518423.2026.2679487
Negative / Null Result ReportMedicine

Association Between Global Positioning System-Based Training Load and Injury Risk in Recreational Runners: A Large Prospective Study.

Cloosterman, de Vos, Willemsen et al. · 2026 · Journal of athletic training

Understanding the relationship between training load and injury in runners may provide information on how to reduce the risk of running injuries. To investigate the association between training load and injury risk in recreational runners…

View details →DOI: 10.4085/1062-6050-0030.25
Negative / Null Result ReportMedicine

Dynapenic abdominal obesity and symptomatic knee osteoarthritis: results from a large cross-sectional study of middle-aged and older adults in China.

Chen, Jiang · 2026 · Annals of joint

Knee osteoarthritis (KOA) is a major cause of disability among middle-aged and older adults worldwide. Emerging evidence suggests that muscle strength may be more relevant than muscle mass for functional outcomes, yet the combined impact…

View details →DOI: 10.21037/aoj-2025-1-79
Negative / Null Result ReportMedicine

No link between piriform cortex subregion resection and seizure freedom in two cohorts with temporal lobe epilepsy.

Zahnert, Pfanzelt, Menzler et al. · 2026 · Journal of neurology

Postoperative seizure freedom in temporal lobe epilepsy (TLE) has been linked to the extent of piriform cortex resection. Earlier work used manual piriform cortex segmentations truncated at the limen insulae and overlapping the amygdala.…

View details →DOI: 10.1007/s00415-026-13850-w
Negative / Null Result ReportMedicine

Investigating the relationship between psychological stress and physical activity through individual-based geographic ecological momentary assessment.

Ge, Wang, Wu et al. · 2026 · Social science & medicine (1982)

Physical Activity (PA) is known to buffer stress, yet evidence remains limited when examining real-time stress responses alongside objective measures of activity and environmental exposures in daily life. To address the gap, this study…

View details →DOI: 10.1016/j.socscimed.2026.119411
Negative / Null Result ReportMedicine

Associations Between Mukbang Watching and Appetite, Nutrition, and Quality of Life in Pediatric Patients with Cancer: Intensive Longitudinal Study.

Xiao, Wang, Zhong et al. · 2026 · Journal of medical Internet research

Malnutrition is prevalent among children with cancer and is often exacerbated by diminished appetite. To combat this, hospitalized children are increasingly adopting mukbang, a popular online eating show genre. This study aimed to assess…

View details →DOI: 10.2196/80932
Negative / Null Result ReportMedicine

Horror Fandom, morbid curiosity, and psychological resilience amid war conflict and economic crisis among university students in Lebanon: a cross-sectional study.

Affan, Yammine, Karam et al. · 2026 · BMC psychology

Psychological resilience is crucial during prolonged instability, allowing individuals to adapt to change demands, manage intense stress, and maintain mental health. Engagement with horror media and morbid curiosity may be associated with…

View details →DOI: 10.1186/s40359-026-04792-z
Negative / Null Result ReportMedicine

Psychiatric hospitalization and rehospitalization among children and adolescents: evidence from 10-years electronic records in Beijing, China.

Zhu, Shi, Xia et al. · 2026 · BMC psychiatry

Enhancing inpatient services for children and adolescent mental illness is a primary goal of medical systems, yet knowledge of child and adolescent psychiatric hospitalization utilization is limited. This study aimed to characterize…

View details →DOI: 10.1186/s12888-026-08162-2
Negative / Null Result ReportMedicine

Views of EU citizens on economic growth and implications for climate policy.

Savin, King, van den Bergh et al. · 2026 · Nature communications

Although economic growth remains a central objective in policymaking and political discourse, its compatibility with environmental sustainability is increasingly contested. Yet it remains unclear whether this debate is reflected in public…

View details →DOI: 10.1038/s41467-026-73323-6
Negative / Null Result ReportMedicine

Predictors of psychosocial burden in parents of children with food allergy.

Kubala, Young, Callier et al. · 2026 · Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

The psychosocial burden of food allergy (FA) impacts the entire family, particularly the affected child and their parents. To evaluate psychosocial parental burden (PB) in families of children with FA, identify factors associated with PB,…

View details →DOI: 10.1016/j.anai.2026.05.010