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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21720 results · page 389 of 724

Negative / Null Result ReportMedicine

Diagnostic Value of Ocular Hemodynamics and Choroidal Thickness in Unilateral Sudden Sensorineural Hearing Loss: Non-Invasive Biomarkers of Systemic Microvascular Disease.

Findik, Kaim, Uzun et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives: Although vascular mechanisms are increasingly implicated in the etiology of sudden sensorineural hearing loss (SSNHL), the inability to directly visualize the labyrinthine artery remains a diagnostic obstacle.…

View details →DOI: 10.3390/diagnostics16121903
Negative / Null Result ReportMedicine

Does Hormonal Phase Affect Acute High-Intensity Interval Training Exercise? An Evaluation of Performance and Fatigue.

Moore, Joniak, Ladan et al. · 2026 · Journal of strength and conditioning research

Moore, SR, Joniak, KE, Ladan, AN, Britton, ME, Cantu, EI, Hirsch, KR, Hackney, AC, and Smith-Ryan, AE. Does hormonal phase affect acute high-intensity interval training exercise? An evaluation of performance and fatigue. J Strength Cond…

View details →DOI: 10.1519/jsc.0000000000005452
Negative / Null Result ReportMedicine

Antimicrobial effect of 1064 nm Nd:YAG laser with flat-top homogeneous beam profile on oral fungal and bacterial biofilms: an in vitro study.

Grzech-Leśniak, Pyrkosz, Szwajkowski et al. · 2026 · Lasers in medical science

This in vitro study aimed to evaluate the antimicrobial effects of a 1064 nm Nd:YAG laser delivered through a novel handpiece designed to provide a flat-top, homogeneous energy distribution profile (MarcoM handpiece) against key oral…

View details →DOI: 10.1007/s10103-026-04921-5
Negative / Null Result ReportMedicine

Alveolar socket preservation with human umbilical cord mesenchymal stem cell-seeded hydroxyapatite-chitosan scaffolds: An in vivo assessment of osteoprotegerin and receptor activator of nuclear factor-κB expression.

Alshaibani, Kamadjaja, Sitalaksmi et al. · 2026 · Journal of molecular histology

Tooth extraction is a common procedure often followed by alveolar bone resorption, which may compromise future implant placement, prosthetic rehabilitation, esthetics, and periodontal support. Hydroxyapatite-chitosan (HA-Chi) scaffolds…

View details →DOI: 10.1007/s10735-026-10874-4
Negative / Null Result ReportMedicine

Metformin and renal dosimetry in patients undergoing [ 177 Lu]Lu-PSMA therapy: reduced kidney absorbed dose without impact on tumor dosimetry.

Siegmund, Delker, Widjaja et al. · 2026 · European journal of nuclear medicine and molecular imaging

Prostate-specific membrane antigen (PSMA)-targeted radiopharmaceutical therapy (RPT) is an established treatment for advanced prostate cancer, but renal radiation exposure remains a major safety concern, as no clinically established…

View details →DOI: 10.1007/s00259-026-08030-x
Negative / Null Result ReportMedicine

Deep Learning Reconstruction Specialized for Inner Ear: Improving Image Quality and Anatomical Structure Visualization as Compared with Conventional Hybrid-Type Iterative Reconstruction on High-Definition CT.

Nomura, Kimata, Ito et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives: To directly compare the capabilities of hybrid-type iterative reconstruction (IR) with the newly developed deep learning reconstruction (DLR) for the inner ear on high-definition CT (HDCT) obtained using the…

View details →DOI: 10.3390/diagnostics16121756
Negative / Null Result ReportOpen access

Subscriptions: Information about subscribing to Stroke is online at at UNIV OF EDINBURGH on Comments, Opinions, and Reviews Good Laboratory Practice Preventing Introduction of Bias at the Bench

Marc Fisher, Ulrich Dirnagl, Geoffrey A Donnan et al. · 2020

Background and Purpose-As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review-Accumulating…

Negative / Null Result ReportOpen access

Feasibility of progesterone treatment for ischaemic stroke

Claire L. Gibson (6162488), Philip M. Bath (3111867) · 2015

Two multi-centre phase III clinical trials examining the protective potential of progesterone following traumatic brain injury have recently failed to demonstrate any improvement in outcome. Thus, it is timely to consider how this impacts…

Negative / Null Result ReportOpen access

Early effect of moderate altitude stress on plasma potassium in the dog

Armand J. Gold, Jeanne Q. Barry, Frederick P. Ferguson · 1960

Exposure of dogs to a simulated altitude of 30,000 feet for 30 minutes resulted in marked respiratory alkalosis and hypokalemia. The data failed to demonstrate, however, the appearance of the early transient hyperkalemic response which has…

View details →DOI: 10.1152/jappl.1960.15.1.37
Negative / Null Result ReportOpen access

Is there any role for the Hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?

Botta, Angela, De Carolis, S, Botta, A. et al. · 2015

The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a…

View details →DOI: 10.1016/j.autrev.2015.04.010
Negative / Null Result ReportOpen access

Carbon dioxide-induced amnesia in the cockroach Periplaneta americana

Wahlsten, Douglas, NC DOCKS at The University of North Carolina at Greensboro · 1968

Cockroaches (Periplaneta americana) learned to passively avoid electric shock in a two-compartment box after a single training trial. However, Ss exposed to CO2 gas immediately after the training trial failed to show retention of the…

Negative / Null Result ReportOpen access

Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study

Mosley, T H, Catellier, D, Sharrett, A R et al. · 2009

Cardiovascular risk factors are associated with a higher risk of developing dementia. Studies in older populations, however, have often failed to show this relationship. We assessed the association between cardiovascular risk factors…

View details →DOI: 10.17615/9nxm-j737
Null DatasetOpen access

Hypera (Eririnomorphus) kunzei Germar 1822

Volovnik, Semyon, Yunakov, Nikolai, Nazarenko, Vitalij et al. · 2018

Hypera (Eririnomorphus) kunzei Germar, 1822 Records. KYI [Cherkunov 1889: 188] Distribution. Central Europe (Skuhrovec 2013) Notes. We failed to find any H. kunzei in material from Ukraine. Meanwhile it resembles H. conmaculata which is…

View details →DOI: 10.5281/zenodo.3802937
Negative / Null Result ReportOpen access

On the Actual EPR Detection of Thioacyl Radicals

Maurizio Guerra (1268337), Angelo Alberti (2426320), Serge Masson (2426323) et al. · 2016

The direct EPR detection of thioacyl radicals has been reported only once, while thioacyl nitroxides remain an elusive species. We failed to detect the thioacyl radicals from two thioaldehydes and from phosphoryldithioformates but have…

View details →DOI: 10.1021/ol801219g.s002
Negative / Null Result ReportOpen access

Convergence of Per Capita GDP Across SAARC Countries

Chowdhury, Khorshed

In this paper we have examined the issue of convergence of per capita GDP across 7 South Asian countries during 1960-2000 using World Bank data. Empirical results failed to find evidence of s convergence, b convergence and conditional b…

Negative / Null Result ReportOpen access

Diversity in Primate External Eye Morphology: Previously Undescribed Traits and Their Potential Adaptive Value

Juan Olvido Perea-García, Monteiro, Antonia, Perea Garcia, J.O. et al. · 2021

Comparative examinations of external eye morphology in primates initially focused on communicative functions of the eye. Subsequent work has failed to find consistent associations between specific eye morphologies and communicative…

View details →DOI: 10.3390/sym13071270