Negative / Null Result ReportOpen accessMedicine
White DE, Ghani U, Pedersen M et al. · 2025 · Journal of neuroengineering and rehabilitation
Background Unilateral nostril breathing (UNB) has a history linked to ancient yogic traditions where it is believed to affect both physical and mental states however the mechanism(s) by which this technique potentially influences brain…
View details →DOI: 10.1186/s12984-025-01782-x Negative / Null Result Report
Köçer MS, Yıldız MK, Akgün BM et al. · 2026 · Preprint
Abstract Learning through play provides children with meaningful and lasting knowledge while fostering empathy, social responsibility, and cooperation. In disaster education, where vital life skills are addressed, game-based approaches…
View details →DOI: 10.21203/rs.3.rs-8517791/v1 Negative / Null Result ReportMedicine
Scalvini S, Donati V, Zanelli E et al. · 2026 · European journal of internal medicine
Background Heart failure (HF) and type 2 diabetes (T2DM) are significant public health concerns. This study evaluated a 6-month home-based telemedicine program for older patients with combined HF and T2DM. The primary outcome was exercise…
View details →DOI: 10.1016/j.ejim.2026.106981 Negative / Null Result Report
Khaleel HM, Alsaffar SF · 2026 · Preprint
Background Polycystic ovarian syndrome (PCOS) is a hormonal, metabolic disorder in women of reproductive age. It can be induced by genetic, immunological, and environmental determinants. The main pathophysiology of PCOS, is…
View details →DOI: 10.12688/f1000research.172281.3 Negative / Null Result ReportMedicine
Guillen B, Zambrano-Huailla R, Chirinos JA · 2026 · Revista de gastroenterologia de Mexico (English)
Introduction The use of artificial intelligence (AI) in endoscopic studies has grown in recent years. The present study evaluates the performance of AI in detecting polyps and adenomas in daily clinical practice. Materials and methods A…
View details →DOI: 10.1016/j.rgmxen.2025.09.028 Negative / Null Result Report
Elabed MH, Jarbou H, Alsalim N et al. · 2026 · Preprint
Background Dentistry is considered a high-risk profession for developing work-related musculoskeletal disorders (MSDs), particularly in the cervical region, due to prolonged static postures, repetitive movements, and sustained neck flexion…
View details →DOI: 10.12688/f1000research.182694.1 Negative / Null Result Report
Haghighi H, Lindsey BW, Jeffries KM · 2026 · Preprint
Temperatures in aquatic ecosystems have been affected by anthropogenic activities such as agricultural and industrial water use, and climate change caused by greenhouse gas emissions. Changes in water temperature directly affect the…
View details →DOI: 10.64898/2026.06.03.729897 Negative / Null Result ReportMedicine
Hollenbach J, Schroth FN, Hildebrand C et al. · 2026 · Placenta
Introduction Osteopontin (OPN) is an extracellular matrix protein secreted by endometrial glands during early pregnancy and is required for adhesion and signal transduction at the uterine-placental surface. In sheep, endometrial OPN…
View details →DOI: 10.1016/j.placenta.2026.06.005 Negative / Null Result ReportMedicine
Sas A, Jónyer D, Valikovics A et al. · 2026 · Journal of clinical medicine
Background/Objectives: Rheumatoid arthritis (RA) has been associated with accelerated atherosclerosis and cerebrovascular alterations. Our 2017 study compared 60 RA patients to healthy controls, assessing vascular, neurological, and…
View details →DOI: 10.3390/jcm15124691 Negative / Null Result ReportMedicine
Sangiorgi G, Cavinato L, Cristoferi M et al. · 2026 · Respiratory medicine
Background Elexacaftor/tezacaftor/ivacaftor (ETI) therapy rapidly improves monocyte antimicrobial activity in people with cystic fibrosis (pwCF). Here, we investigated the effect of long-term ETI therapy on Pseudomonas aeruginosa…
View details →DOI: 10.1016/j.rmed.2026.108930 Negative / Null Result ReportMedicine
Gökcek Taraç M, Çolak M · 2026 · American journal of dentistry
Purpose To evaluate the effects of two commonly used pediatric medical syrups on the surface roughness and the adhesion of Streptococcus mutans (S. mutans) to three fluoride-releasing restorative materials: high-viscosity glass-ionomer,…
Negative / Null Result ReportMedicine
Houska N, McCaw N, Meneses EC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives To describe thrombotic outcomes associated with Factor Eight Inhibitor Bypassing Activity (FEIBA) exposure in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass (CPB), including the Norwood procedure.…
View details →DOI: 10.1053/j.jvca.2026.05.071 Negative / Null Result ReportMedicine
Almuashi H, AbuMostafa A · 2026 · Quintessence international (Berlin, Germany : 1985)
Objective The management of pain in dental procedures is crucial, as local anesthetic injections may induce patient anxiety and discomfort. Various techniques including Vibraject and Dentapen have been devised to alleviate injection…
View details →DOI: 10.3290/j.qi.b7010719 Negative / Null Result ReportMedicine
Veli-Quispe D, Urquizo-Prado S, Cesare-Ariza E et al. · 2026 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Background Cerebrovascular disease remains a leading cause of mortality worldwide. In Peru, evidence on recent mortality trends and regional disparities is limited. Objective To evaluate temporal trends and regional disparities in…
View details →DOI: 10.1016/j.jstrokecerebrovasdis.2026.108675 Negative / Null Result ReportMedicine
Qin LG, Camarda ND, Kasetty VM et al. · 2026 · Journal of vitreoretinal diseases
Purpose: To investigate the effect of intravitreal (IVT) aflibercept injection monotherapy on retinal ischemia in eyes with severe proliferative diabetic retinopathy (PDR) that underwent pars plana vitrectomy (PPV) without panretinal…
View details →DOI: 10.1177/24741264261445228 Negative / Null Result ReportMedicine
Li DY, Kim S, Javed S et al. · 2026 · Regional anesthesia and pain medicine
Background Methadone is commonly used as an alternative to other opioids for managing cancer-related pain. High-dose methadone, primarily in opioid dependence treatment, has been associated with QTc prolongation and dangerous arrhythmias.…
View details →DOI: 10.1136/rapm-2025-107328 Negative / Null Result ReportOpen accessMedicine
Švajger U, Kolar M, Pompe B et al. · 2026 · Cartilage
ObjectiveUmbilical cord-derived mesenchymal stromal cells (UC-MSCs) are a promising treatment for knee osteoarthritis (KOA). This study aimed to (1) characterize early synovial fluid biomarker changes after intra-articular UC-MSCs therapy…
View details →DOI: 10.1177/19476035261435793 Negative / Null Result ReportMedicine
Ramachandran I, Rajesh AT, Elumalai P · 2026 · Fish physiology and biochemistry
The current study aimed to ascertain the growth, antioxidant capacity, intestinal architecture, digestive enzyme activity, and disease resistance of S. agalactiae of Nile tilapia (Oreochromis niloticus) fed a diet enriched with…
View details →DOI: 10.1007/s10695-026-01683-3 Negative / Null Result Report
Rocco C, Larrouy-Maumus G, Wissuwa M et al. · 2026 · Preprint
1 Summary Zinc (Zn) deficiency limits rice productivity and poses a risk to human health, particularly in populations reliant on rice-based diets. Although rice germplasm exhibits wide variation in Zn-deficiency tolerance, the underlying…
View details →DOI: 10.64898/2026.03.16.711580 Negative / Null Result ReportOpen accessMedicine
Kaba Ö, Tanatar A, Koç R et al. · 2026 · Jornal de pediatria
Objectives Colchicine is an essential component of familial Mediterranean fever (FMF) treatment. It is suggested that it may affect vitamin B 12 levels by affecting intestinal absorption. This research focused on examining the impact of…
View details →DOI: 10.1016/j.jped.2026.101554 Negative / Null Result ReportMedicine
Kim S, Kim JH, Shin JY et al. · 2026 · Age and ageing
Background Depression is common in older adults, who are also at elevated risk of bleeding due to age-related physiological changes and comorbidities. Concerns have been raised regarding potential bleeding risk from concomitant use of…
View details →DOI: 10.1093/ageing/afag105 Negative / Null Result ReportOpen accessMedicine
Wang R, Dai P, Deng X et al. · 2026 · Journal of thoracic disease
Background Thymoma is an uncommon cancer of the thymus and postoperative radiotherapy (PORT) is often considered for selected patients with high-risk or locally advanced thymoma after resection. The effect of PORT on overall survival (OS)…
View details →DOI: 10.21037/jtd-2026-1-0184 Negative / Null Result Report
Bolton A · 2026 · Preprint
Abstract While the ecological effects of internal combustion engines are well documented, especially in susceptible arctic areas like Svalbard, effects on specific genera of plants are largely neglected. The Saxifraga genus was selected…
View details →DOI: 10.21203/rs.3.rs-9763836/v1 Negative / Null Result Report
Au YE, Baskaran R, Li JY et al. · 2026 · Preprint
Abstract Background The ability to appraise and apply research is fundamental to the practice of evidence-based medicine (EBM). Despite the General Medical Council’s (GMC) mandate for United Kingdom (UK) medical graduates to integrate…
View details →DOI: 10.21203/rs.3.rs-8150678/v1 Negative / Null Result ReportOpen accessMedicine
Patel M, Schwartz K, Schenk M et al. · 2026 · Orthopaedic journal of sports medicine
Background Ulnar collateral ligament (UCL) reconstruction (UCLR) of the elbow is common in throwing athletes and reliably allows return to play. The literature supports stress imaging of the elbow to evaluate the integrity of the UCL. The…
View details →DOI: 10.1177/23259671261453313 Negative / Null Result ReportOpen accessMedicine
Kumar P, Gordon A, Fisher E et al. · 2026 · The Australian & New Zealand journal of obstetrics & gynaecology
Background Routine third trimester ultrasound scans have been introduced in several maternity centres to increase detection of fetal growth disorders and improve perinatal outcomes. Aims To assess changes in obstetric and neonatal outcomes…
View details →DOI: 10.1111/ajo.70139 Negative / Null Result ReportOpen accessMedicine
Kasowanjete P, Dhilip Kumar SS, Houreld N · 2026 · Lasers in medical science
The phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT), mammalian target of rapamycin (mTOR) (PI3K/AKT/mTOR) pathway regulates cell survival, proliferation, and the synthesis of protein. Photobiomodulation (PBM) stimulates…
View details →DOI: 10.1007/s10103-026-04859-8 Negative / Null Result ReportOpen accessMedicine
Shannon ES, Sparks SA, McNaughton LR et al. · 2026 · European journal of applied physiology
PURPOSE: Hydrogen cation (H+) accumulation is exacerbated in hypoxia. Sodium bicarbonate (NaHCO3) ingestion can reduce fatigue associated with high-intensity exercise performance by counteracting H+ ion accumulation. The present study…
View details →DOI: 10.1007/s00421-025-06069-6 Negative / Null Result ReportOpen accessMedicine
Ayyildiz BG, Terzioglu B, Eken S · 2026 · Journal of applied oral science : revista FOB
Objective This study aimed to compare the effectiveness of injectable platelet-rich fibrin (I-PRF) using a submucosal injection technique for creeping attachment in thin and thick phenotypes with gingival recession. Methodology The study…
View details →DOI: 10.1590/1678-7765-2025-0702 Negative / Null Result Report
Mobarak A, Chatterjee U, Munoz J et al. · 2026 · Preprint
Abstract The Swachh Bharat Mission - Gramin (SBM-G) was launched by the Prime Minister of India in 2014 during his inaugural independence-day address, as a flagship program to eliminate open defecation in India by 2019. Touted as the…
View details →DOI: 10.21203/rs.3.rs-3411309/v1 