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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20240 results in Negative / Null Result Report · page 359 of 675

Negative / Null Result ReportMedicine

Are horned cows in loose housing more stressed than hornless cows? a cross-sectional study in organic dairy farms.

Ebinghaus A, Thiessen G, Ivemeyer S et al. · 2025 · Animal : an international journal of animal bioscience

In commercial dairy farming, the majority of cows are dehorned or genetically hornless. It is argued that this reduces the risk of injurious and stressful social conflicts. On the other hand, in horned herds, management and housing may be…

View details →DOI: 10.1016/j.animal.2024.101405
Negative / Null Result ReportOpen accessMedicine

Sport fans' self-esteem and supporting the team that won over the favorite.

Takemura E, Matsuoka H · 2026 · Frontiers in sports and active living

Research purpose Most often, when their favorite team loses, sports fans are disappointed by the outcome and hostile to the winning team. However, in the tournaments, they also sometimes voice their support for the team that eliminated…

View details →DOI: 10.3389/fspor.2026.1810401
Negative / Null Result ReportOpen accessMedicine

Earlier first-time memory clinic visits during the COVID-19 pandemic: A comparison of dementia severity and caregiver burden.

Maeda A, Suzuki M, Suzumura S et al. · 2026 · Journal of family medicine and primary care

Introduction The coronavirus disease 2019 pandemic prompted widespread restrictions on daily activities, leading to concerns over delayed medical consultations. However, limited social interaction outside the home may have increased the…

View details →DOI: 10.4103/jfmpc.jfmpc_1621_25
Negative / Null Result ReportMedicine

Skittering locomotion in cricket frogs: a form of porpoising.

Weiss T, Gillis GB, Van Mullekom J et al. · 2024 · The Journal of experimental biology

Multiple species of frogs in the Ranidae family have been observed to 'skitter' across the water surface, but little is understood about the biomechanical or physical mechanisms that underlie this behavior. All documented descriptions are…

View details →DOI: 10.1242/jeb.249403
Negative / Null Result ReportOpen accessMedicine

Mentalizing on the edge: borderline traits and their association with real-time self-reflection - an ecological momentary assessment study.

Höller I, Schwitzky S, Forkmann T et al. · 2026 · Borderline personality disorder and emotion dysregulation

Background Mentalization plays a key role in borderline personality disorder (BPD), yet its moment-to-moment fluctuations remain understudied. This study is the first to use established self-report items within an Ecological Momentary…

View details →DOI: 10.1186/s40479-026-00347-1
Negative / Null Result ReportMedicine

Nanopatterns on silica scales of Mallomonas (Chrysophyceae, Stramenopiles): Unraveling UV resistance potential and diverse response to UVA and UVB radiation

Němcová Y, Knotek P, Jadrná I et al. · 2024 · Journal of phycology

Mallomonas thrive primarily in freshwaters and dominate plankton communities, especially in oligotrophic waters. The cells have a siliceous cell covering of regularly arranged scales. Despite their ecological importance, the intricate…

Negative / Null Result Report

Migration strategies of a high-latitude breeding songbird ( Setophaga coronata coronata ) revealed using multi-sensor geolocators and stable isotopes

Szarmach SJ, Beam JK, Moore M et al. · 2024 · Preprint

ABSTRACT Seasonal migration allows animals to use habitat where conditions are unfavorable for part of the year but may constrain breeding ranges due to the costs of longer migrations as ranges expand poleward. In species with large…

View details →DOI: 10.1101/2024.10.09.617415
Negative / Null Result ReportMedicine

Exposure to structural racism-related state laws is associated with worse cardiovascular health among US adults, BRFSS 2011 and 2013.

Needham BL, Dokshina D, Ali T et al. · 2025 · American journal of epidemiology

The objective of this study was to determine whether exposure to structural racism-related state laws is associated with cardiovascular health among a racially and ethnically diverse sample of US adults. Data were from the Database of…

View details →DOI: 10.1093/aje/kwae176
Negative / Null Result ReportMedicine

Expression of CD226 on γδ T cells is lower in advanced chronic lymphocytic leukemia and correlates with IgA, IgG and LDH levels.

Zarobkiewicz MK, Lehman N, Kowalska W et al. · 2025 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Gamma-delta (γδ) T cells comprise an important subset of human T cells, responding to viral and bacterial infections, and are significant for cancer immunosurveillance. Human γδ T cells are divided into 5 major subsets, namely…

View details →DOI: 10.17219/acem/186335
Negative / Null Result ReportMedicine

Exploring fonts as retrieval cues in text-based learning.

Krieglstein F, Jansen S, Meusel F et al. · 2024 · Acta psychologica

A growing body of research focuses on optimizing retrieval processes to help learners recall information from memory. The context-dependent memory effect suggests that information retrieval is more effective when the retrieval context…

View details →DOI: 10.1016/j.actpsy.2024.104606
Negative / Null Result ReportOpen accessMedicine

Combining Endoscopic Submucosa Dissection and Endoscopic Full-Thickness Resection for Resection of a Gastric Schwannoma Mimicking Gastrointestinal Stroma Tumor.

Kormann S, Semadeni GM, Weber M et al. · 2024 · ACG case reports journal

Subepithelial gastric tumors are a diagnostic challenge. Endoscopic ultrasound allows differentiation. Lesions originating from the submucosal layer can be resected using endoscopic submucosal dissection (ESD). Surgery or endoscopic…

View details →DOI: 10.14309/crj.0000000000001440
Negative / Null Result ReportOpen accessMedicine

Inadequacy of interventions to eliminate or reduce violence against healthcare professionals by patients and/or their relatives.

Yöyen E, Barış TG · 2026 · World journal of psychiatry

Workplace violence (Type II), which is defined as verbal, physical and sexual assault behaviour directed at healthcare workers by patients and their relatives, is a complex concept arising from a variety of individual, social, economic,…

View details →DOI: 10.5498/wjp.v16.i2.113936
Negative / Null Result ReportMedicine

Multi-parametric magnetic resonance imaging of the prostate in Victoria, Australia; unintended consequences of changing Medicare Benefits Schedule access.

Gordon P, Urquhart E, Oad S et al. · 2024 · Australian health review : a publication of the Australian Hospital Association

Objective To assess whether prostate biopsy rates have altered with the July 2018 change in Australian Medicare Benefits Schedule (MBS) rebates supporting multiparametric magnetic resonance imaging (mpMRI) for diagnosing prostate cancer.…

View details →DOI: 10.1071/ah24024
Negative / Null Result ReportOpen accessMedicine

Attachment representations in Afghan refugees undergoing psychological treatment: a pilot study.

Egger T, Gander M, Dumser B et al. · 2025 · European journal of psychotraumatology

Background: Refugees are at elevated risk of trauma-related disorders. Unresolved attachment is a vulnerability factor for post-traumatic stress, yet its role in Afghan refugees remains underexplored. This is the first study to assess…

View details →DOI: 10.1080/20008066.2025.2582456
Negative / Null Result ReportOpen accessMedicine

A Case of Unexpected Peritoneal Carcinomatosis From Colon Cancer Detected After Robot-Assisted Radical Cystectomy for Advanced Bladder Cancer.

Ito K, Yamashita R, Kasai S et al. · 2026 · IJU case reports

Introduction Peritoneal carcinomatosis in patients with advanced bladder cancer is a rare but lethal event following robot-assisted radical cystectomy (RARC). We report a case of an unusual clinical course in which peritoneal dissemination…

View details →DOI: 10.1002/iju5.70155
Negative / Null Result ReportMedicine

Integrating vision and somatosensation does not improve the accuracy and response time when estimating area and perimeter of rectangles in primary school.

Leukel C, Loibl K, Leuders T · 2024 · Trends in neuroscience and education

Background Problem-solving and learning in mathematics involves sensory perception and processing. Multisensory integration may contribute by enhancing sensory estimates. This study aims to assess if combining visual and somatosensory…

View details →DOI: 10.1016/j.tine.2024.100238
Negative / Null Result ReportOpen accessMedicine

Conscious and Resilient? Associations Between Temperament, Emotional Awareness, and Emotion Regulation Strategies in Youth.

Struyf S, Koster EHW, Van Beveren ML et al. · 2026 · Psychologica Belgica

Introduction Emotion regulation (ER) plays a crucial role in children and adolescents' emotional well-being. However, the use of adaptive strategies often remains challenging during early adolescence, partly because cognitive functions…

View details →DOI: 10.5334/pb.1399
Negative / Null Result ReportMedicine

Seasonal Sulfur Redox Cycling in Two Constructed Wetlands with Insight on How They Age.

Lindelien CM, Xu X, Knox AS et al. · 2024 · Bulletin of environmental contamination and toxicology

Long-term metal remediation in wetland treatment systems (WTSs) involves facilitating dissimilatory sulfate reduction to produce sulfide and mineralize metals in deep sediments. We evaluated seasonal sulfur cycling in two constructed…

View details →DOI: 10.1007/s00128-024-03942-6
Negative / Null Result ReportOpen accessMedicine

Sodium zirconium cyclosilicate post hospital discharge to prevent hyperkalaemia: phase 4, randomized CONTINUITY trial.

Burton JO, Izquierdo MJ, Linde C et al. · 2026 · Clinical kidney journal

Background and hypothesis Hyperkalaemia is common and potentially life-threatening in individuals with chronic kidney disease (CKD). While sodium zirconium cyclosilicate (SZC) is used in the hospital setting for hyperkalaemia management,…

View details →DOI: 10.1093/ckj/sfag158
Negative / Null Result ReportMedicine

Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.

Colombel JF, Garcia Olmo D, Chen ST et al. · 2026 · Gastroenterology

Background & aims The ADMIRE CD trial demonstrated the efficacy and safety of darvadstrocel in patients with complex perianal fistulas from Europe and Israel. The efficacy and safety of darvadstrocel in an expanded patient population was…

View details →DOI: 10.1053/j.gastro.2025.12.033
Negative / Null Result ReportMedicine

Icotinib plus chemotherapy as neoadjuvant treatment for resectable stage II-IIIB EGFR-mutant lung adenocarcinoma: a phase II study (NEOIPOWER).

Lu F, Lv C, Yang X et al. · 2025 · Lung cancer (Amsterdam, Netherlands)

Background EGFR tyrosine kinase inhibitors (EGFR-TKIs) have shown activity in the neoadjuvant setting of EGFR-mutant (EGFRm) non-small cell lung cancer; however, data on the combination of neoadjuvant EGFR-TKIs plus chemotherapy are…

View details →DOI: 10.1016/j.lungcan.2025.108676
Negative / Null Result ReportMedicine

Efficacy and safety of intravenous prasinezumab in individuals with early-stage Parkinson's disease on stable symptomatic monotherapy (PADOVA): a phase 2b, multicentre, randomised, double-blind, placebo-controlled study.

Nikolcheva T, Pagano G, Anzures-Cabrera J et al. · 2026 · Lancet (London, England)

Background Prasinezumab has previously shown potential for reducing the progression of motor signs (Movement Disorder Society-sponsored Revision of the Unified Parkinson's Disease Rating Scale [MDS-UPDRS] Part III) in patients with…

View details →DOI: 10.1016/s0140-6736(26)00865-2
Negative / Null Result ReportMedicine

Safety and efficacy of the anti-α-synuclein monoclonal antibody amlenetug for the treatment of patients with multiple system atrophy (AMULET): a phase 2, randomised, double-blind, multicentre trial.

Kjærsgaard L, Wiedemann J, Singer W et al. · 2026 · The Lancet. Neurology

Background Pathological aggregation and propagation of α-synuclein species drive disease progression in multiple system atrophy (MSA). We assessed the efficacy and safety of amlenetug, a monoclonal antibody targeting aggregated…

View details →DOI: 10.1016/s1474-4422(26)00100-6