Negative / Null Result ReportOpen accessMedicine
Davis AE, Su Y, Dallas R et al. · 2026 · Emerging microbes & infections
Human astroviruses are a common cause of viral gastroenteritis and are often underdiagnosed. While infections are typically mild or asymptomatic in immunocompetent hosts, astrovirus can cause prolonged and severe disease in…
View details →DOI: 10.1080/22221751.2026.2616946 Negative / Null Result ReportOpen accessMedicine
Mittal A, Malhotra K, Panwar V et al. · 2026 · Urology research & practice
Objective: This retrospective cross-sectional analytical study evaluated the clinicopathological associations of programmed death ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2/neu) expression in 250 patients with…
View details →DOI: 10.5152/tud.2026.25061 Negative / Null Result Report
Bahta H, Kahsay A, Mewcha G · 2026 · Preprint
This study aims to assess beekeeper’s perceptions of honeybee colony behavior, climate related challenges and hive productivity in Tigray. The research design was used a mixed-approach method with multi-stage sampling techniques to select…
View details →DOI: 10.22541/authorea.15004610/v1 Negative / Null Result ReportOpen accessMedicine
Qiao X, Wang Y, Tian Z et al. · 2026 · Frontiers in psychiatry
Aim To explore the symptom distress and quality of life status of patients with Chronic Kidney Disease (CKD) Stage 5 undergoing hemodialysis in China, and their correlation. Methods The Dialysis Symptom Index (DSI) and the Kidney Disease…
View details →DOI: 10.3389/fpsyt.2026.1733502 Failed Experiment ReportMedicine
Düsünen E, Tural E, Yonak AK et al. · 2026 · The National medical journal of India
Background Diabetic foot ulcers are an important problem for people with diabetes mellitus. We aimed to determine the mortality rate in patients with diabetic foot ulcers and assess the relationship between mortality, the Wagner…
View details →DOI: 10.25259/nmji_536_2024 Abandoned Hypothesis
Sommer K, Russell S, Paynter J · 2026 · Preprint
This pre-registered study examined whether autistic preschool children could learn novel words from a social robot during a shared eBook reading session, how their engagement with the robot relates to word learning, and whether their…
View details →DOI: 10.31234/osf.io/nf6mh_v2 Negative / Null Result ReportMedicine
Meade-Aguilar JA, Stovall R, Ramiro S et al. · 2026 · Joint bone spine
Objectives There are limited data on how NSAID use and dosage influence hypertension risk in axial spondyloarthritis (axSpA). We evaluated the association between NSAID use and incident hypertension in a longitudinal axSpA inception…
View details →DOI: 10.1016/j.jbspin.2026.106059 Negative / Null Result ReportOpen accessMedicine
Gonzalez DE, Dickerson BL, Hines K et al. · 2026 · Sports (Basel, Switzerland)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
View details →DOI: 10.3390/sports14040137 Negative / Null Result ReportMedicine
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
View details →DOI: 10.1007/s10072-026-08967-9 Negative / Null Result ReportMedicine
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
View details →DOI: 10.1186/s40360-026-01177-1 Negative / Null Result ReportMedicine
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
View details →DOI: 10.1186/s12884-026-09529-9 Negative / Null Result ReportOpen accessMedicine
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
View details →DOI: 10.4103/jfmpc.jfmpc_320_25 Negative / Null Result ReportOpen accessMedicine
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
View details →DOI: 10.1038/s41398-026-03878-x Negative / Null Result Report
Isikoglu BD, Senler FC · 2026 · Preprint
Abstract Purpose. Insomnia is a heterogeneous symptom cluster of multiple etiologies, frequently encountered in oncology patients, and chemotherapy has been implicated as a contributing factor. We aimed to evaluate the effects of…
View details →DOI: 10.21203/rs.3.rs-9973460/v1 Negative / Null Result Report
Coban S, Yavuz S, Dogan C et al. · 2026 · Preprint
Abstract Background Emergency department overcrowding is a persistent global public health issue, often driven by non-urgent visits. Health literacy is considered a key determinant of appropriate healthcare utilization. Objective This…
View details →DOI: 10.21203/rs.3.rs-9744500/v1 Negative / Null Result ReportOpen accessMedicine
Hiroshimaya T, Iwai K, Marutani M et al. · 2026 · Scientific reports
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis…
View details →DOI: 10.1038/s41598-026-40128-y Replication FailureOpen accessMedicine
Amuji DN, Iweala EEJ · 2026 · BMC cancer
BACKGROUND: Breast cancer (BC) is a major cause of cancer-related mortality among women worldwide. Genetic polymorphisms, such as those in the Mesenchymal Epithelial Transition factor (MET) proto-oncogene, may influence cancer risk and…
View details →DOI: 10.1186/s12885-026-15844-3 Replication FailureOpen accessMedicine
Liu Y, Zhong S, Zhong K et al. · 2026 · Frontiers in endocrinology
Aim To investigate the association between history of gestational diabetes mellitus (GDM) and the risk of hypertensive disorders of pregnancy in subsequent pregnancy (s-HDP). Methods A retrospective cohort of 5, 928 women with two…
View details →DOI: 10.3389/fendo.2026.1736779 Negative / Null Result ReportMedicine
Dos Santos, Sauruk da Silva, Iacomini et al. · 2026 · Pharmaceuticals (Basel, Switzerland)
Background : Ganoderma lucidum is a medicinal mushroom widely recognized for its high content of bioactive polysaccharides, particularly β-glucans with immunomodulatory properties. This study aimed to optimize polysaccharide…
View details →DOI: 10.3390/ph19060946 Negative / Null Result ReportOpen accessMedicine
Haddad A, Zabari Parnis E, Stein N et al. · 2026 · Vaccines
Background/Objective : The emergence of the COVID-19 pandemic has raised significant concerns regarding its impact on immune-mediated diseases, particularly with respect to disease induction and exacerbation. We aimed to investigate the…
View details →DOI: 10.3390/vaccines14040289 Negative / Null Result ReportOpen accessComputer Science
Ihsan Kahveci, Timothy A. Thomas, Nathalie E. Williams et al. · 2026 · arXiv
Home eviction poses a significant threat to housing stability, a critical determinant of health. This study examines the relationship between eviction and health and substance use within the unhoused population of King County, Washington. Using a sample of 1,106 individuals experiencing homelessness, we employed a quasi-experimental design to compare the health outcomes of those who have experienced eviction with those who have not. Our findings reveal eviction is associated with an 8.3% point increase (SE = 0.039) in the likelihood of reporting poor general health and an 9.5% increase (SE = 0
Negative / Null Result ReportOpen accessComputer Science
Maximilian Warsinke, Maurizio Vergari, Tanja Kojić et al. · 2025 · arXiv
This study explores how prior exposure to physical objects influences the quality and realism perception of Digital Twins (DT) with varying levels of fidelity in Virtual Reality (VR). In a mixed experimental design, 24 participants were divided into two equal groups: an exposure group, in which members were shown physical objects before inspecting and rating their replicas in VR, and a control group without prior knowledge. Three objects were presented, each under four fidelity conditions with varying texture resolution and geometric detail. Participants rated perceived quality and realism thr
Negative / Null Result ReportOpen accessComputer Science
Rahul Arora, Jiannan Li, Gongyi Shi et al. · 2021 · arXiv
Size and distance perception in Virtual Reality (VR) have been widely studied, albeit in a controlled laboratory setting with a small number of participants. We describe a fully remote perceptual study with a gamified protocol to encourage participant engagement, which allowed us to quickly collect high-quality data from a large, diverse participant pool (N=60). Our study aims to understand medium-field size and egocentric distance perception in real-world usage of consumer VR devices. We utilized two perceptual matching tasks -- distance bisection and size matching -- at the same target dista
Negative / Null Result ReportOpen accessComputer Science
Samuel Westby, Richard J. Radke, Christoph Riedl et al. · 2023 · arXiv
Voice assistants are increasingly prevalent, from personal devices to team environments. This study explores how voice type and contribution quality influence human-agent team performance and perceptions of anthropomorphism, animacy, intelligence, and trustworthiness. By manipulating both, we reveal mechanisms of perception and clarify ambiguity in previous work. Our results show that the human resemblance of a voice assistant's voice negatively interacts with the helpfulness of an agent's contribution to flip its effect on perceived anthropomorphism and perceived animacy. This means human tea
Negative / Null Result ReportMedicine
Gou, He, Zhuo · 2026 · Frontiers in medicine
To investigate the effect and safety of astragalus injection at Neiguan (PC6) for chronic heart failure (CHF; HF) with qi-deficiency and blood-stasis syndrome, and its effect on the renin-angiotensin-aldosterone system (RAAS). A…
View details →DOI: 10.3389/fmed.2026.1836620 Negative / Null Result ReportOpen accessMathematics
Jens Rauch, Jens Hüsers, Birgit Babitsch et al. · 2018 · arXiv
Frequent users of emergency departments (ED) pose a significant challenge to hospital emergency services. Despite a wealth of studies in this field, it is hardly understood, what medical conditions lead to frequent attendance. We examine (1) what ambulatory care sensitive conditions (ACSC) are linked to frequent use, (2) how frequent users can be clustered into subgroups with respect to their diagnoses, acuity and admittance, and (3) whether frequent use is related to higher acuity or admission rate. We identified several ACSC that highly increase the risk for heavy ED use, extracted four majo
Negative / Null Result ReportOpen accessComputer Science
F. W. Bopp, Yu. M. Shabelski · 2006 · arXiv
The process of baryon number transfer due to string junction propagation in rapidity space is considered. It leads to a significant effect in the net baryon production in pA collisions at mid-rapidities and an even more significant effect in the forward hemisphere for the cases of πA interactions. The results of numerical calculations in the framework of the Quark-Gluon String Model are in reasonable agreement with the data. Special consideration is given to Λproduced in {π^-}-A collisions extracted from data of WA89 Collaboration.
Negative / Null Result ReportOpen accessPhysics
Narayan Khadka, Michal Zajaček, Swayamtrupta Panda et al. · 2022 · arXiv
We use observations of 66 reverberation-measured \Mgii\ quasars (QSOs) in the redshift range $0.36 \leq z \leq 1.686$ -- a subset of the 78 QSOs we previously studied that also have \rfe\ (flux ratio parameter of UV \Feii\ to \Mgii\ that is used as an accretion-rate proxy) measurements -- to simultaneously constrain cosmological model parameters and QSO 2-parameter and 3-parameter radius-luminosity ($R-L$) relation parameters in six different cosmological models. We find that these QSO $R-L$ relation parameters are independent of the assumed cosmological model and so these QSOs are standardiza
Negative / Null Result ReportOpen accessPhysics
Rabiah A. Rahmat, Melissa A. Humphries, Jeremy J. Austin et al. · 2020 · arXiv
Heat alters colour and crystallinity of teeth by destruction of the organic content and inducing hydroxyapatite crystal growth. The colour and crystallite changes can be quantified using spectrophotometric and x-ray diffraction analyses, however these analyses are not commonly used in combination to evaluate burned dental remains. In this study, thirty-nine teeth were incinerated at 300-1000$^\circ$C for 15 and 30 minutes and then measured using a spectrophotometer and an x-ray diffractometer. Response variables used were lightness, L$^\ast$, and chromaticity a$^\ast$ and b$^\ast$ and luminanc
Negative / Null Result ReportOpen accessPhysics
E. Forgacs-Dajka · 2006 · arXiv
We present detailed numerical calculations of the fast solar tachocline based on the assumption that the dynamo field dominates over the dynamics of the tachocline. In the present paper of the series, we focus on three shortfalls of the earlier models. First, instead of the simple oscillating dipole poloidal field we study the more general magnetic field structures reminiscent of the butterfly diagram. The migrating field is prescribed as the observed axisymmetric radial magnetic field Stenflo (1988, 1994). Our results are in good agreement with our analitical estimate and our previous works i
