Negative / Null Result ReportMedicine
O'Leary C, Yoong E, Matsika A et al. · 2025 · Asia-Pacific journal of clinical oncology
Aims Castrate-resistant prostate cancer (CRPC) is a common malignancy with poor prognostic outcomes. Breast cancer (BRCA) genes 1 and 2 mutations occur in prostate cancers and confer poorer prognoses. Somatic BRCA testing can lead to…
View details →DOI: 10.1111/ajco.70011 Negative / Null Result ReportMedicine
Makgoka TR, De Villiers M, Van Zyl DG · 2025 · South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Background Tuberculosis (TB) is a major contributor to mortality among patients affected by HIV. TB diagnosis can be challenging, especially in those who are severely ill and unable to produce sputum. Urine lipoarabinomannan (LAM) is a…
View details →DOI: 10.7196/samj.2025.v115i2.2143 Negative / Null Result ReportMedicine
Wang T, Park B, Anderson G et al. · 2024 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Early diagnosis of invasive fungal disease is essential for optimizing management. Although the clinical utility of fungal polymerase chain reaction (PCR) testing on plasma and bronchoalveolar lavage (BAL) has been established,…
View details →DOI: 10.1093/cid/ciae382 Negative / Null Result ReportOpen accessMedicine
May J, Waturangi DE, Tan WA et al. · 2026 · Scientific reports
Biofilm-forming bacteria, such as Bacillus cereus and Vibrio harveyi are major contributors to food contamination and problems in aquaculture. This study aimed to evaluate the antibiofilm compounds of the phyllosphere bacterial…
View details →DOI: 10.1038/s41598-026-34989-6 Negative / Null Result ReportMedicine
Zheng J, Guo Q, Yue G et al. · 2025 · World journal of urology
Objective There is ongoing debate regarding whether patients with a positive urine culture (UC) need to wait for the culture to turn negative following antimicrobial treatment before undergoing percutaneous nephrolithotomy (PCNL). This…
View details →DOI: 10.1007/s00345-025-05484-w Negative / Null Result ReportMedicine
Leech J, Sauer BM, Baduashvili A et al. · 2025 · Neurology. Clinical practice
Background and objectives The presence of oligoclonal bands (OCBs) indicates an augmented immune response within the CNS and is integral to the diagnosis of multiple sclerosis (MS). Expert consensus panels recommend OCB testing for…
View details →DOI: 10.1212/cpj.0000000000200510 Negative / Null Result ReportMedicine
Wezenberg BN, Koster M, van Wingen G et al. · 2025 · Schizophrenia research
Objective Sleep disturbances and brain alterations are common in psychotic disorders and individuals at clinical high risk for psychosis (CHR-P). It remains unclear whether gray matter volume changes are inherent to psychosis or partly…
View details →DOI: 10.1016/j.schres.2025.09.010 Negative / Null Result ReportOpen accessMedicine
Boardman-Pretty F, Kumar J, Grant C et al. · 2026 · Orphanet journal of rare diseases
BACKGROUND: Accurate and early diagnosis to optimise rare disease care is a global priority. With recent developments in artificial intelligence (AI)-based solutions, a promising area to improve rare disease diagnosis is the application of…
View details →DOI: 10.1186/s13023-026-04240-6 Negative / Null Result ReportMedicine
Wells MJ, Casleton BG, Gella MM et al. · 2025 · Open Forum Infectious Diseases
Background All blood donors in the United States are universally screened once for Trypanosoma cruzi antibodies to prevent transfusion-transmitted Chagas disease, but military donors are screened with every donation. Previous studies of…
View details →DOI: 10.1093/ofid/ofaf522 Negative / Null Result ReportOpen accessMedicine
Montagud AC, Moragues R, Gabaldón-Bravo EM et al. · 2025 · BMC public health
BACKGROUND: The primary immunization against SARS-CoV-2 has yielded protection rates of up to 95%. The evolution of the original strain of SARS-CoV-2 towards emerging variants which have higher transmissibility, severity of disease and…
View details →DOI: 10.1186/s12889-025-24077-1 Negative / Null Result ReportOpen accessMedicine
Butler D, O'Flaherty N, Coyne D et al. · 2026 · Epidemiology and infection
Cytomegalovirus (CMV) is a ubiquitous virus with significant public health implications, including severe morbidity and mortality in neonates and immunosuppressed individuals. Substantial variation in CMV prevalence has been reported…
View details →DOI: 10.1017/s0950268826101137 Negative / Null Result ReportOpen accessMedicine
Andersson Å, Ferrari P, Bakó I et al. · 2026 · The journal of physical chemistry. A
The gas-phase structures of capped phenylated polyalanine peptides, Ac-Ala-Ala-Phe-Ala-NH 2 (AAFA) and Ac-Ala-Ala-Phe-Ala-Ala-NH 2 (AAFAA), were investigated using conformer-selective IR-UV ion dip spectroscopy employing the IR light of…
View details →DOI: 10.1021/acs.jpca.5c05537 Negative / Null Result ReportMedicine
Russo V, Comune A, Parente E et al. · 2025 · The American journal of cardiology
The impairment of baroreflex sensitivity (BRS) has been hypothized in patients with vasovagal syncope (VVS). The aim of our study was to assess the baroreflex sensitivity in patients with suspected vasovagal syncope who underwent head up…
View details →DOI: 10.1016/j.amjcard.2025.07.046 Negative / Null Result ReportMedicine
Ali M, Baban Y, Kumar G · 2026 · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
To retrospectively examine the outcome of the antinuclear antibody (ANA) screen by comparing the performance of BioPlex 2200 and immunofluorescence assay (IFA). We reviewed the ANA screening results performed on the BioPlex 2200 using…
View details →DOI: 10.1177/10815589251348924 Methods Dead-End
Back S, Gu E, Han K et al. · 2025 · Preprint
Abstract Background Hwanglyeonhaedok-tang (HHT), also known as Huang-lian-jie-du-tang or Oren-gedoku-to, is a popular herbal formula in traditional Asian medicine. Despite the clinical effectiveness of herbal formulas, concerns regarding…
View details →DOI: 10.21203/rs.3.rs-6303752/v1 Negative / Null Result ReportOpen accessMedicine
Legler M, Heenemann K · 2025 · Veterinary sciences
The common swift is the most observed swift species in Germany. During the summer months in urban areas, juvenile swifts in need of help are frequently cared for in wild bird rescue centers. Providing adequate housing and veterinary…
View details →DOI: 10.3390/vetsci12121117 Negative / Null Result ReportMedicine
Zosim V, Mullie C, Peltier F et al. · 2025 · Molecular biology reports
Background Antimicrobial resistance (AMR) in Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (ESKAPE pathogens), notably in carbapenem-resistant…
View details →DOI: 10.1007/s11033-025-10826-3 Negative / Null Result ReportOpen accessMedicine
Atobatele S, Mpimbaza A, Ngufor C et al. · 2025 · Malaria journal
Background Malaria rapid diagnostic tests (RDTs) have improved case management and surveillance across sub-Saharan Africa by reducing presumptive treatment and enhancing diagnostic specificity. However, healthcare workers' (HCWs) concerns…
View details →DOI: 10.1186/s12936-025-05674-2 Negative / Null Result ReportMedicine
Ebner R, Braach J, Rübenthaler J et al. · 2025 · Journal of nuclear medicine : official publication, Society of Nuclear Medicine
The aim of this retrospective study was to evaluate the correlation between findings from somatostatin receptor (SSTR) PET/CT and histopathology in patients with suspected intracranial meningiomas. Methods: We conducted a retrospective…
View details →DOI: 10.2967/jnumed.125.270115 Negative / Null Result Report
Atobatele S, Mpimbaza A, Ngufor C et al. · 2025 · Preprint
Abstract Background Malaria rapid diagnostic tests (RDTs) have improved case management and surveillance across sub-Saharan Africa by reducing presumptive treatment and enhancing diagnostic specificity. However, healthcare workers’ (HCWs)…
View details →DOI: 10.21203/rs.3.rs-7194605/v1 Negative / Null Result ReportOpen accessMedicine
Horn EJ, Menefee B, Schotthoefer AM et al. · 2026 · Journal of clinical microbiology
Current laboratory testing for Lyme disease (LD) relies on serology. We evaluated the performance of standard two-tiered testing (STTT) and modified two-tiered testing (MTTT) algorithms using samples obtained from well-characterized…
View details →DOI: 10.1128/jcm.01187-25 Null DatasetOpen accessMedicine
Lisha W, Jiao Q, Mengyuan C et al. · 2025 · Microbiology spectrum
Regarding metagenomics next-generation sequencing (mNGS) negative literature, there have been much discussions about methodology; thus, we collected clinical and laboratory information for retrospective evidence-based research. We…
View details →DOI: 10.1128/spectrum.02013-24 Null DatasetOpen accessMedicine
Marland V, Nisbet L, Nic Daéid N · 2025 · Harm reduction journal
Background The detection of nitazene compounds in the United Kingdom has raised concerns among healthcare professionals, public health authorities, and law enforcement due to the increased risk of fatal overdose, particularly among opioid…
View details →DOI: 10.1186/s12954-025-01287-9 Negative / Null Result ReportOpen accessMedicine
Baumgarten J, Stephan E, Ohlwärther TEN et al. · 2026 · Forensic science, medicine, and pathology
Estimation of the postmortem interval (PMI) of found bones is an important and challenging part of forensic osteology assessments. This study examined human long bones that had been taken from cemeteries and hoarded by a "bone collector".…
View details →DOI: 10.1007/s12024-025-01140-2 Negative / Null Result ReportOpen accessMedicine
Sheybani L · 2026 · The European journal of neuroscience
A recent study by Hausdorf et al. reported that combining closed-loop acoustic stimulation with transcranial direct current stimulation during sleep does not improve memory consolidation. This contrasts with past studies that reported a…
View details →DOI: 10.1111/ejn.70400 Negative / Null Result ReportOpen accessMedicine
Pruss A, Skierska A, Kwiatkowski P et al. · 2025 · PloS one
Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. Carbapenemases are enzymes that help bacteria to exhibit the strongest resistance against…
View details →DOI: 10.1371/journal.pone.0318852 Negative / Null Result Report
Ngufor C, Lindblade KA, Atobatele S et al. · 2025 · Preprint
Abstract Background Rapid diagnostic tests (RDTs) have improved malaria case management by enabling point-of-care confirmation of infection, particularly in low-resource settings. In addition to clinical use, RDT results recorded in health…
View details →DOI: 10.21203/rs.3.rs-6760274/v1 Negative / Null Result ReportOpen accessMedicine
Bolterstein E, Mungre S, Nuss K et al. · 2025 · microPublication biology
WRNexo and Blm , Drosophila orthologs of human WRN and BLM RecQ helicases, play crucial roles in DNA replication and repair. Using a Course-based Undergraduate Research Experience (CURE) in an introductory Biology course, we investigated…
View details →DOI: 10.17912/micropub.biology.001620 Negative / Null Result ReportMedicine
Uedo N, Gotoda T, Takizawa K et al. · 2026 · The American journal of gastroenterology
Introduction The recommendation to discontinue low-dose aspirin (LDA) during the periprocedural period of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) remains controversial in patients at low thrombotic risk. If…
View details →DOI: 10.14309/ajg.0000000000003928 Negative / Null Result ReportOpen accessMedicine
Zabir MOH, Habib MA, Monalisa et al. · 2026 · IJID regions
Objectives Acute respiratory infections (ARIs) such as influenza-like illness (ILI) and severe acute respiratory infection (SARI) are leading causes of morbidity among children aged under 5 years (under-5) in Bangladesh. In Cox's Bazar,…
View details →DOI: 10.1016/j.ijregi.2026.100921 