A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21294 results · page 334 of 710
Daubney ER, Flatley C, Hwang LD et al. · 2025 · Behavior genetics
Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal…
Groncki R, Beaudry JL, Sauer JD · 2021 · Memory (Hove, England)
The way in which individuals think about their own cognitive processes plays an important role in various domains. When eyewitnesses assess their confidence in identification decisions, they could be influenced by how easily relevant…
Patel KR, Pugh SL, Simko JP et al. · 2026 · Advances in radiation oncology
Purpose The cyclin-dependent kinase inhibitor p27 is a well-profiled modulator of cell cycle progression. Low nuclear p27 levels have been demonstrated to have a negative prognostic impact on outcomes in patients undergoing prostatectomy.…
Fu CK, Lee HT, Yang YC et al. · 2025 · In vivo (Athens, Greece)
Background/aim Gastric adenocarcinoma (GACA) remains a major global health concern, particularly in Asia, due to its poor prognosis and complex etiology. The interaction between genetic factors and environmental exposures, such as smoking,…
Papadopoulos E, Rozenberg D, Wong AKO et al. · 2025 · PloS one
Background Skeletal muscle index (SMI), grip strength, and physical performance have been shown to predict clinically relevant outcomes in geriatric oncology. However, their predictive ability for chemotherapy toxicity is poorly…
Shook NJ, Oosterhoff B · 2020 · Politics and the life sciences : the journal of the Association for Politics and the Life Sciences
Disgust has been consistently associated with greater political conservatism. Two explanations have been proposed for this link. According to a pathogen threat model, disgust serves a pathogen-avoidance function, encouraging more…
Centorame G, Warrington NM, Hemani G et al. · 2025 · Behavior genetics
Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids, which are essential for brain development. In 2007, Caspi et al. found evidence in two cohorts for an…
Torchiano A, Roberts B, Haroz R et al. · 2025 · The western journal of emergency medicine
Introduction Prescribing patients buprenorphine from the emergency department (ED) is recommended by multiple organizations. However, it is unclear how best to encourage physicians to prescribe buprenorphine from the ED. Our objectives in…
Shen CY, Li CP, Yu JT et al. · 2026 · In vivo (Athens, Greece)
Background/aim Resveratrol, a polyphenolic compound found in grapes, berries, and peanuts, has been linked to antioxidant, anti-inflammatory, and vasoprotective effects. Yet, evidence from randomized controlled trials (RCTs) remains…
Liu J, Catanzariti MJ, Nguyen-Hao HT et al. · 2026 · Journal of neuropathology and experimental neurology
Alcohol use disorder (AUD) is characterized by an inability to stop consuming alcohol. Neuroimaging studies of patients with AUD show mild grey and white matter atrophy, while pathological studies suggest that atrophy is restricted to the…
Udry J, Barber SJ · 2025 · Cognition
Inoculation interventions aim to improve discernment between true and false information, but their effectiveness with older adults is unknown. It is also unknown whether inoculation interventions are effective when misinformation is…
Belmaker RH · 2025 · Pharmaceuticals (Basel, Switzerland)
Lithium was the first discovered mood stabilizer for bipolar disorder. However, several antiepileptics such as valproate and carbamazepine have also proven to be mood stabilizers in all phases of bipolar disorder with profiles barely…
French B, Chiaro NVD, Holmes NP · 2022 · Experimental brain research
The grating orientation discrimination task (GOT) is a sensitive and reliable measure of tactile spatial resolution, or acuity. We used the GOT in three experiments to investigate the effects of hand posture and hand visibility on spatial…
Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
Ferhatlar ME, Cumhur BA, Koca Y et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose The aim of this study is to prospectively compare the diagnostic performance of the PECARN, CATCH, and CHALICE clinical decision rules in pediatric patients presenting with minor head trauma, within a rural secondary-level…
Zarghami Y, Rad MG, Mafeld S et al. · 2026 · Scientific reports
Continual automated pain detection from facial expressions using computer vision during procedural sedation could optimize sedation dose titration and minimize pain. A prospective observational study was conducted. Participants' faces were…
Balraam Kv V, Nayak AR, Dass J et al. · 2026 · Journal of pediatric hematology/oncology
Background Systemic mastocytosis (SM) with associated acute myeloid leukemia (AML) is a rare malignancy usually linked to KIT p.D816V mutations. Observations We report a 17-year-old female with RUNX1::RUNX1T1-positive AML and florid mast…
Nayak S, Deshmukh P, Yadav SR et al. · 2026 · Preprint
Ledebouria , a geophytic herb native genus to Africa and represented by a few species in the Arabian Peninsula, Madagascar, India and Sri Lanka. For a long time Indian species were named as L. revoluta until recent molecular work clarified…
Slis A, Parrell B · 2026 · Journal of cognitive neuroscience
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
Frick A, Whyte-Fagundes P, Baraban SC · 2026 · Preprint
Syntaxin-binding protein 1 ( STXBP1 ) mutations lead to severe epilepsy, intellectual disability, developmental delay, and movement disorder. Effective treatments for these conditions do not exist. Recent studies in Munc18-1 ( STXBP1 ) C.…
Kaiser A, Resasco J, Dee LE · 2026 · Nature ecology & evolution
Urban environments pose unique challenges for understanding drivers of biodiversity change, as fragmented land ownership makes traditional biodiversity monitoring and randomized experiments logistically difficult. While participatory…
Trivedi S, Simons NW, Tyagi A et al. · 2026 · Preprint
Background Large language models (LLMs) are increasingly used in mental health contexts, yet their detection of suicidal ideation is inconsistent, raising patient safety concerns. Methods We conducted a cross-sectional evaluation using 224…
Swanstein HKJ, Gommeren K, Langhorn R et al. · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
Objective To describe point-of-care ultrasound (POCUS) and clinical findings in cats with high-rise syndrome. Design Retrospective descriptive study. Setting University hospital. Animals Fourteen cats that fell from a height. Measurements…
Romano F, Overbey K, Durocher-Jean A et al. · 2026 · Ophthalmic surgery, lasers & imaging retina
Background and objective This study describes a novel hyperspectral imaging (HSI) approach for visualizing and measuring geographic atrophy (GA) lesions in age-related macular degeneration. Patients and methods This cross-sectional…
Akinci D'Antonoli T, Adams LC, Lübberstedt J et al. · 2026 · European radiology
Objectives To evaluate whether GPT-4.1 and Llama 3.3 70B, large language models (LLMs) assessed in zero-shot, baseline configurations, detect and categorize clinically consequential errors across types that range from pattern-based to…
Elkordy MS · 2026 · Preprint
Underground utilities represent a critical risk factor in large-scale water infrastructure projects, particularly in dense urban environments such as Riyadh, KSA. This paper presents a comparative technical assessment of three primary…
Boersma J, Gregg J, Nason D et al. · 2026 · Preprint
Searching for lost species– those without conclusive documentation for a decade or longer– has emerged as a core goal of conservationists during the current extinction crisis. While documenting these species is an important first step,…
Hasan D, Sauer J, Heller C et al. · 2026 · Clinical neuroradiology
Purpose Hemorrhagic transformation (HT) within ischemic infarcts is a critical post-stroke complication that significantly influences secondary prevention strategies, particularly the timing and safety of anticoagulation. Ultra-low field…
Theingi M, Ruengdit C, Punyamung M et al. · 2026 · Laboratory medicine
Introduction This study aimed to characterize the molecular and hematologic features of hemoglobin (Hb) Hekinan II in northern Thailand and to evaluate its phenotypic expression when co-inherited with other hemoglobinopathies. Methods In…
Genç S, Uzun AN, Tanriverdi̇ H · 2026 · Folia microbiologica
Carbapenem resistance in Klebsiella pneumoniae is primarily mediated by carbapenemase production. This study aimed to identify carbapenemase genes in carbapenem-resistant K. pneumoniae isolates using multiplex polymerase chain reaction…