A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21713 results · page 334 of 724
Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PdC et al. · 2024 · Preprint
Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…
Houben M, Rief W, Gärtner T et al. · 2024 · Preprint
Abstract Background: Depression is related to a reduced update of negative expectations in response to positive information. Here, we aimed to replicate that cognitive immunization (a cognitive devaluation of expectation-disconfirming…
Whiteford KL, Baltzell LS, Chiu M et al. · 2024 · Preprint
Musical training has been associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a large-scale multi-site…
Zhou Y, Tse CS · 2025 · The Journal of general psychology
In English, head is associated with rationality and logic, whereas heart is related to feeling and emotionality. In Chinese, these head- and heart-related metaphors also exist. Could these head- and heart-related conceptual metaphors…
Noel M, Suttapitugsakul S, Cummings RD et al. · 2024 · Preprint
Protein O-glycosylation is a critical modification in the brain, as genetic variants in the pathway are associated with both common and severe neuropsychiatric phenotypes. However, little is known about the most abundant type of O-glycan…
Wickenhagen A, Flagg M, Port J et al. · 2024 · Preprint
The emergence of the Omicron lineage represented a major genetic drift in SARS-CoV-2 evolution. This was associated with phenotypic changes including evasion of pre-existing immunity and decreased disease severity. Continuous evolution…
Stüber AT, Heimer MM, Ta J et al. · 2025 · European journal of radiology
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset.…
Centorame G, Warrington NM, Hemani G et al. · 2024 · Preprint
Background Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids (LC-PUFA), which are essential for brain development. In 2007, Caspi et al. found evidence in…
Wiesing M, Zimmermann E · 2023 · Preprint
Intentional actions produce a temporal compression between the action and its outcome, known as intentional binding. However, Suzuki et al. (2019) recently showed that temporal compression can be observed even without intentional actions.…
Lloyd B, Wurm F, de Kleijn R et al. · 2023 · Preprint
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising brain stimulation method for the treatment of pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced…
Ahrens A, Liesefeld HR, Kinner J et al. · 2026 · Psychological research
In everyday life, we often generalize previously learned associations between our actions and their outcomes to novel, but similar situations. The present study aimed to conceptually and directly replicate results reported by Esser et al.…
Wentura D, Gurbuz E, Paulus A et al. · 2023 · Journal of experimental psychology. Human perception and performance
When asked to judge or react to a facial emotional display of a person, people do not only take the emotion into account, but also other socially important features of the face, such as, for example, ethnicity (Kozlik & Fischer, 2020;…
Dede A, Xiao W, Vaci N et al. · 2023 · Preprint
Abstract Neurodevelopmental disorders are difficult to diagnose, requiring expert clinicians and subjective judgements. Consequently, there has been interest in finding quantitative biomarkers for some disorders using resting state…
Marshall K, Thothathiri M · 2023 · Preprint
Comprehenders make predictions about the meaning and structure of linguistic information as the utterance unfolds. However, when the actual content does not match the expectation, costly reanalysis processes are required. Previous work has…
Whyte-Fagundes P, Vance A, Carroll A et al. · 2023 · Preprint
Dravet syndrome (DS) is a severe genetic epilepsy primarily caused by de novo mutations in a voltage-activated sodium channel gene (SCN1A). Patients face life-threatening seizures that are largely resistant to available anti-seizure…
Lucchi F, Lloyd B, Nieuwenhuis S · 2024 · Psychophysiology
The vagus nerve is thought to be involved in the allostatic regulation of motivation and energy metabolism via gut-brain interactions. A recent study by Neuser and colleagues (2020) provided novel evidence for this process in humans, by…
Hermans P, Vandevoorde K, Orban de Xivry J · 2023 · Preprint
In motor adaptation, learning is thought to rely on a combination of several processes. Two of these are implicit learning (incidental updating of the sensory prediction error) and explicit learning (intentional adjustment to reduce target…
Jiang S, Jones M, von Bastian C · 2023 · Preprint
Abstract In recent years, non-invasive brain stimulation has been highlighted as a possible intervention to induce cognitive benefits, including on visual working memory (VWM). However, findings are inconsistent, possibly due to…
Yang Z, Pajuste FD, Zguro K et al. · 2025 · Nature genetics
Understanding disease progression is of high biological and clinical interest. Unlike disease susceptibility, whose genetic basis has been abundantly studied, less is known about the genetics of disease progression and its overlap with…
Horton CB Jr, Adam H, Galinsky AD · 2025 · Personality & social psychology bulletin
Enclothed cognition refers to the systematic influence that clothes can have on the wearer's feelings, thoughts, and behaviors through their symbolic meaning. It has attracted considerable academic and nonacademic interest, with the 2012…
Chen TA, Chuang YT, Pai SC et al. · 2025 · Microorganisms
Ventilator-associated pneumonia (VAP) remains a significant concern in intensive care units (ICUs), contributing to increased morbidity, mortality, and healthcare costs. Probiotics and synbiotics have been explored as potential preventive…
Alben N, Arthur C · 2024 · Attention, perception & psychophysics
In the present paper, we carry out a replication of a seminal paper by Kahneman, D. & Beatty, J. (1967). Perception & Psychophysics, 2(3),101-105 for using pupillometry as an implicit measure of auditory processing load, specifically,…
Dede AJO, Xiao W, Vaci N et al. · 2023 · Preprint
ABSTRACT Mental health conditions are difficult to diagnose, requiring expert clinicians and subjective judgements. There has been interest in finding quantitative biomarkers using resting state electroencephalogram (EEG) data. Here, we…
Aicoboaie S, Pappaianni E, Abdulkadir M et al. · 2025 · Psychological medicine
Background Shared genetic risk has been shown across psychiatric disorders. In particular, anorexia nervosa (AN), obsessive-compulsive disorder (OCD), and schizophrenia (SCZ) show shared genetic risk that matches clinical evidence of…
Bechtel GN, Kostelnik CJ, Rausch MK · 2025 · Journal of biomedical materials research. Part A
Tissue mimicking materials are designed to represent real tissue in applications such as medical device testing and surgical training. Thanks to progress in 3D-printing technology, tissue mimics can now be easily cast into arbitrary…
Saladini F, Giannini A, Giammarino F et al. · 2026 · Open forum infectious diseases
Background HIV-1 sub-subtype A6 is predominant in Eastern Europe and was associated with increased risk of treatment failure with the long-acting cabotegravir plus rilpivirine regimen. In this study, we aimed to evaluate the in vitro…
Hoth KF, Voorhies K, Wu AC et al. · 2022 · Journal of psychiatry and brain science
Depression is the most common mental illness in the U.S. affecting nearly 40 million adults age 18 years and older. Depression has both genetic and environmental influences. In addition, women are more likely to be affected by depression…
Fang J, Cao Y, Ni J · 2023 · Preprint
Background: Intracranial aneurysm (IA) accounts for a substantial source of non-traumatic subarachnoid hemorrhage, with inflammation postulated as a potential factor in its pathogenesis. The present study aims at evaluating the association…
Davis CN, Jinwala Z, Justice AC et al. · 2025 · Alcohol, clinical & experimental research
Background Topiramate reduces alcohol consumption in individuals who drink heavily. Candidate gene studies aimed at identifying genetic variants that predict topiramate's effects on drinking have yielded inconsistent findings. To identify…
Bender O, Shemesh OA, Bar DZ · 2026 · Journal of Alzheimer's disease : JAD
The etiology of Alzheimer's disease (AD) remains a subject of intense investigation. While the 2024 Lancet Commission report attributes approximately 45% of global dementia cases to 14 modifiable risk factors, it notably excludes…