A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21713 results · page 332 of 724
Jin X, Wang J, Du YJ et al. · 2026 · Medicine
Epidemiological evidence suggests that there is an association between systemic lupus erythematosus (SLE), type 1 diabetes (T1D), ankylosing spondylitis (AS), celiac disease (CD), and cognitive impairment (CI). However, the causal…
Fahimi Z, Kazemi M, Rahimi H et al. · 2025 · IBRO neuroscience reports
Background Post-stroke epilepsy (PSE) is a significant complication in stroke survivors, yet early diagnostic biomarkers remain unclear. This study investigated whether circulating microRNA-219 (miR-219) could serve as a reliable biomarker…
Rosoff DB, Bell AS, Wagner J et al. · 2024 · Cellular and molecular gastroenterology and hepatology
Background & aims Observational studies have linked lipid-lowering drug targets pro-protein convertase subtilisin/kexin 9 (PCSK9) and HMG-CoA reductase (HMGCR) with adverse liver outcomes; however, liver disease incidence varies across…
Kube T, Herzog P · 2023 · Journal of clinical psychology
Background Recent research suggests that dysfunctional expectations are a particularly important subtype of cognitions in depression. However, it is unclear whether depressive symptoms are related to the presence of negative expectations,…
Xie H, Ratner K, Estevez M et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
The Claremont Purpose Scale (CPS) was designed to assess youth purpose, but the English version has not yet undergone rigorous psychometric evaluation among adolescents. Prior validation efforts have also mostly relied on white-majority…
Han S, Long NM · 2025 · Imaging neuroscience (Cambridge, Mass.)
Engagement of the retrieval state (or mode) is theorized to be a precursor to successful retrieval, but precisely when the retrieval state is engaged is unclear. Our aim in the present study is to determine the time course of retrieval…
Tamasauskiene L, Gradauskiene B · 2024 · Journal of inflammation (London, England)
Background T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved in allergic inflammation. The aim is to…
Guerrero-Aranda A, Enríquez-Zaragoza A, López-Jiménez K et al. · 2024 · Clinical EEG and neuroscience
Background. Sleep is an activation procedure and is considered the most potent and best-documented modulator of seizures and interictal epileptiform discharges (IEDs) on electroencephalogram (EEG). The precise role of sleep deprivation in…
Fasha TA, Rajuddin R, Dewi TP et al. · 2026 · Narra J
Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial tissue outside the uterine cavity. Diagnostic delays are common due to nonspecific symptoms and the absence of…
Liu Y, Zhang H · 2025 · Medicine
This study aimed to investigate the bidirectional causal relationship between celiac disease (CD) and the risk of Alzheimer disease (AD) or frontotemporal dementia (FTD) using Mendelian randomization (MR), in order to clarify prior…
Kösem A, Dai B, McQueen JM et al. · 2022 · Preprint
During listening, brain activity tracks the rhythmic structures of speech signals. Here, we directly dissociated the contribution of neural tracking in the processing of speech acoustic cues from that related to linguistic processing. We…
Jozefowiez J, Huff AG, Petruzzo L et al. · 2026 · Journal of experimental psychology. Animal learning and cognition
The expression of an association between a conditioned stimulus (CS) and an aversive unconditioned stimulus (US) can be weakened by presenting the CS by itself (extinction [Ext]), pairing it with an appetitive US (counterconditioning…
Ochal M, Lewczuk KG, Dragańska E et al. · 2026 · Scientific reports
Low back pain (LBP) is one of the most prevalent musculoskeletal complaints and a leading cause of disability worldwide. Although patients frequently attribute symptom exacerbation to adverse weather, the scientific evidence for a direct…
Wilson PR, Bridges KH, Scofield M et al. · 2024 · Pain management
Nonopioid analgesics serve to improve analgesia and limit side effects and risks of perioperative opioids. N-acetylcysteine (NAC), the primary treatment of acetaminophen toxicity, may have perioperative indications, including analgesia.…
Kaicher C, Markman E, Gwilliams L · 2026 · Preprint
Labels are often advantageous for category learning. However, this may not be true for children as they learn subordinate, fine-grained object categories. In preparation for future research on subordinate category learning in children, we…
Wendler M, Leister D, Kleine T · 2026 · The New phytologist
Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast-localized PPR-SMR protein, remains a central yet poorly…
Mallus F, Yang Y, Kia SM et al. · 2026 · Preprint
Abstract Spectral features derived from electroencephalography (EEG) have long been proposed as biomarkers of brain dysfunction, yet few have gained consensus or entered clinical practice. A key obstacle is the lack of harmonized,…
Gottfried JA, Shen C, Morgan D et al. · 2026 · Optics express
In a previous publication [Opt. Express21, 28182 (2013)10.1364/OE.21.028182], Daido et al . reported that solid samples of metallic sodium exhibited high transparency of vacuum ultraviolet light through several millimeter-thick samples.…
Azaad S, Laham S, Sebanz N · 2026 · Preprint
Evidence from joint action research suggests that a suite of spontaneous cognitive and perceptual processes underpins our ability to coordinate with others. We tested whether people spontaneously perceive affordances (or action…
Weber S, Kemp SA, Hinder MR · 2026 · Cognitive, affective & behavioral neuroscience
Action cancellation represents a fundamental aspect of human motor control. Nonetheless, the behavioural paradigms used to study it are methodologically diverse and capture an incompletely understood combination of processes. Advancing…
Macaulay C, Scheepers C · 2025 · Preprint
A Theory of Magnitude (AToM) (Walsh, 2003; Walsh, 2014) attempts to explain avisuo-spatial bias observed across magnitude processing domains (e.g., numerical, temporal).It proposes a generalised processing system which maps mental…
Wladis EJ, Aakalu VK, Dagi Glass LR et al. · 2026 · Ophthalmology
Objective To review the literature on the benefits and risks of systemic corticosteroids in the setting of orbital cellulitis. Methods A literature search was last performed in the PubMed database in August 2025. Articles were limited to…
Benyoucef R, Goubet M, Barrat A et al. · 2026 · European radiology
Objectives External validation of six radiomic models published in three studies: two distinguishing benign from malignant lesions (study 1) and four distinguishing pleomorphic adenomas from Warthin's tumors (studies 2 and 3). Materials…
Tenney ER, Rochford K, Stillwell A et al. · 2026 · Psychological science
This is a registered report to directly replicate the primary finding in Hecht and Proffitt (1995). Hecht and Proffitt found that those with occupational experience handling liquid in containers performed worse at solving a water-level…
Jajcay N, Tomeček D, Fajnerová I et al. · 2026 · Preprint
An increasing number of studies are currently focusing on ‘personality neuroscience’, a term denoting the research aimed at neuroimaging correlates of inter-individual temperament and character variability. Among other methods, a graph…
Chandran S, Vinjé J, Huynh K et al. · 2026 · Preprint
Human intestinal enteroids (HIE) and zebrafish larvae (ZF) models support the replication of certain strains of human norovirus (HuNoV), the leading cause of viral gastroenteritis worldwide. The replication of 17 HuNoV (9 genotypes)…
Dhanda N, Ziano I, Ching KH et al. · 2025 · Personality & social psychology bulletin
This article presents preregistered replications of three influential studies in the field of escalation of commitment and regret aversion. In Study 1, we found partial support for Staw's (1976) article on the effects of personal…
Pachunka A, Jeffries JB, Karr L et al. · 2025 · Preprint
Interacting with animals can improve health and well-being across the lifespan. Some programs such as 4-H and FFA center around youth interacting with animals, potentially enhancing youth development. Mueller (2014) investigated whether…
Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the second study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could foster resistance to anti-vaccine conspiracy theories without significantly…
Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…