Negative / Null Result ReportOpen accessMedicine
Tardif A, Boulay ME, Côté A et al. · 2026 · Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
BACKGROUND: Tezepelumab is the most recent human monoclonal antibody in the therapeutic arsenal of patients with severe uncontrolled asthma. It neutralizes thymic stromal lymphopoietin (TSLP). Phase 2 and phase 3 studies showed a…
View details →DOI: 10.1186/s13223-026-01037-x Negative / Null Result ReportOpen accessMedicine
Fu Y, Zhang Y, Deng Q et al. · 2025 · BMC psychiatry
Background Post-stroke depression (PSD) constitutes an important complication of stroke, affecting approximately one-third of stroke patients. PSD decreases rehabilitation motivation, delays function recovery, and increases the family and…
View details →DOI: 10.1186/s12888-025-06673-y Negative / Null Result ReportMedicine
Kateh Shamshiri M, Vakili-Ghartavol R, Aiyelabegan HT et al. · 2025 · Cytokine
While liposomes enhance the safety and pharmacokinetic profile of free drugs, they have not significantly improved therapeutic efficacy. To overcome this challenge, targeted depletion of tumor-associated macrophages (TAMs) shows…
View details →DOI: 10.1016/j.cyto.2025.156860 Negative / Null Result ReportMedicine
Lamboley Q, Fourcade Y · 2024 · Journal of biogeography
AIM: The continuous development of statistical tools applied to ecology has contributed to great advances for modelling species' niches and distributions from opportunistic observations. However, as these observations are subject to biases…
Negative / Null Result ReportMedicine
Alghizzi TM, Alshahrani TM · 2024 · Heliyon
Despite considerable evidence that supports the use of grading rubrics (GRs) as tools for written corrective feedback, there is a paucity of research that investigates which of the different types of GRs best develops learners'…
Negative / Null Result Report
Siegrist H, Spieler A, Peters AS et al. · 2024 · Preprint
There is currently no clinically valid biomarker for predicting the growth and prognosis of abdominal aortic aneurysms (AAA). The most promising candidates with highest diagnostic values are plasma D-dimers and markers of activated…
View details →DOI: 10.20944/preprints202410.2260.v1 Negative / Null Result Report
Lefebvre C, Tiffay A, Breemeersch C et al. · 2024 · Preprint
Rationale Obesity is often associated with sex-dependent metabolic complications, in which altered intestinal barrier function and gut microbiota contribute. Glutamine (Gln) supplementation previously showed beneficial effects on gut…
View details →DOI: 10.1101/2024.11.21.624683 Negative / Null Result ReportOpen accessMedicine
Bousamaki J, Maciag G, Petersen AG et al. · 2026 · Basic & clinical pharmacology & toxicology
Nintedanib, a multitargeted tyrosine kinase inhibitor, is approved for idiopathic pulmonary fibrosis (IPF) for its ability to slow lung function decline. This study systematically evaluated the effects of nintedanib across three…
View details →DOI: 10.1111/bcpt.70220 Negative / Null Result ReportMedicine
Güngör HS, Łabuz G, Yildirim TM et al. · 2024 · Journal of refractive surgery (Thorofare, N.J. : 1995)
Purpose To investigate how varying levels of longitudinal chromatic aberration (LCA) affect visual quality in patients with trifocal intraocular lenses (IOLs). Methods Twenty-nine patients implanted with trifocal IOLs were assessed for…
View details →DOI: 10.3928/1081597x-20240731-03 Negative / Null Result ReportOpen accessMedicine
Hui Q, Xiang T, Qinglan X et al. · 2026 · Food science & nutrition
The link between Vitamin D (Vit D) deficiency and sudden sensorineural hearing loss (SSNHL), especially regarding recurrence and age-related disparities, remains unclear. Recurrence and age-specific risks of SSNHL are under addressed,…
View details →DOI: 10.1002/fsn3.71383 Negative / Null Result ReportOpen accessMedicine
Tanabe S, Shi Y · 2024 · The American journal of case reports
BACKGROUND Retained products of conception (RPOC) is a rare complication following second-trimester delivery or pregnancy termination, often leading to significant hemorrhage. Diagnosed via ultrasound or CT, RPOC requires surgical…
View details →DOI: 10.12659/ajcr.945672 Negative / Null Result ReportMedicine
Hyun J, Cerino ES, Katz MJ et al. · 2025 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives Investigating social determinants of health and related outcomes may help identify effective and sustainable intervention targets. This study examined whether contextual-level social capital (bonding and bridging capital) and…
View details →DOI: 10.1093/geronb/gbaf157 Negative / Null Result ReportOpen accessMedicine
Kumekawa T, Akaihata H, Natsuya H et al. · 2024 · IJU case reports
Introduction Human T-cell lymphotropic virus type 1 infection can cause HTLV-1-associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary…
View details →DOI: 10.1002/iju5.12773 Negative / Null Result Report
Su X, Zhang L, Sun Y et al. · 2024 · Preprint
Abstract Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion, thereby impacting energy utilization. This study aimed to explore the impact of grain variety and…
View details →DOI: 10.21203/rs.3.rs-4958601/v1 Negative / Null Result ReportOpen accessMedicine
Nikolaeva A, Vandeputte M · 2025 · Endocrinology, diabetes & metabolism case reports
Summary Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering its potential…
View details →DOI: 10.1530/edm-25-0081 Negative / Null Result ReportMedicine
El Idrissi Y, El Moudden H, Belhoussaine O et al. · 2025 · Chemistry & biodiversity
This study investigates for the first time the effects of UV light exposure on the chemical composition of artisanal and cold-pressed culinary and cosmetic argan oils, as well as their quality and biological activities. We ascertained the…
View details →DOI: 10.1002/cbdv.202401262 Negative / Null Result ReportMedicine
Jhaj J, Woolner B, Rankin S et al. · 2025 · Shoulder & elbow
This study evaluated the outcome and recurrence rates after hydrodilatation (HD) in patients with frozen shoulder (FS), comparing the effects of injecting 25 mL or more of fluid versus lower volumes. A total of 132 shoulders (130 patients)…
View details →DOI: 10.1177/17585732241307860 Negative / Null Result ReportMedicine
Banerjee S, Berry Y, Fisher E et al. · 2025 · Neuroscience letters
Genetic leukoencephalopathy (gLE) is a white matter disorder affecting the central nervous system, causing hypomyelination, developmental delays, motor deterioration, and cognitive, visual, and hearing impairments. Its clinical variability…
View details →DOI: 10.1016/j.neulet.2025.138280 Negative / Null Result ReportMedicine
Alsheekh A, Kibrik P, Marks N et al. · 2025 · Vascular
BackgroundThe minimally invasive procedures of venous ablation and iliac vein stenting are evolving treatment options for venous insufficiency. Yet, there are no studies directly comparing the outcome of these procedures. We performed a…
View details →DOI: 10.1177/17085381241273222 Negative / Null Result ReportMedicine
Agergaard J, Gunst JD, Schiøttz-Christensen B et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Knowledge is limited on how changing SARS-CoV-2 variants may translate into different characteristics and affect the prognosis of patients with long COVID, especially following Omicron variants. We compared long-term prognosis…
View details →DOI: 10.1016/j.ijid.2023.10.022 Negative / Null Result Report
Narayanan A, Khashram M, Fisher JP · 2024 · Preprint
Abstract High stress may diminish a surgeon’s performance in the operating room (OR). Music is perceived to reduce stress in the OR, however the psycho-physiological effects of music on intra-operative stress in inexperienced and…
View details →DOI: 10.21203/rs.3.rs-4225405/v1 Negative / Null Result Report
Pascha MN, Ballegeer M, van Haperen R et al. · 2024 · Preprint
Antibodies targeting hemagglutinin and neuraminidase (NA) are key components of the adaptive immune response against influenza A virus (IAV). However, antigenic drift allows the virus to escape inhibition by such antibodies. In this study,…
View details →DOI: 10.1101/2024.09.03.611041 Negative / Null Result ReportOpen accessMedicine
Carroll AM, Pruitt DT, Riley JR et al. · 2024 · Scientific reports
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning on sensory and…
View details →DOI: 10.1038/s41598-024-69666-z Negative / Null Result ReportOpen accessMedicine
Langley C, Plakotaris E, Rogers NE · 2025 · Case reports in dermatology
Introduction Lichen planopilaris (LPP) is a well-known cicatricial alopecia with a frontal fibrosing variant. LPP has a prevalence rate of 13.4 per 100,000 persons. It is understood that LPP favors the female populations. What is not…
View details →DOI: 10.1159/000546867 Negative / Null Result ReportOpen accessMedicine
Panca M, Serfaty M, Satchell J et al. · 2026 · BJPsych open
Background Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims This paper aims to evaluate the cost-effectiveness of a victim improvement package (VIP) for the reduction…
View details →DOI: 10.1192/bjo.2025.10937 Negative / Null Result ReportOpen accessMedicine
Fernandes Cabral DT, Fernández-de Thomas RJ, Alattar A et al. · 2024 · Neurosurgical focus: Video
Odontoid pannus is an abnormal collection of degenerative or inflammatory tissue on the C1-dens joint that can result in severe spinal cord compression myelopathy. Treatment options vary depending on severity and etiology. In cases of…
View details →DOI: 10.3171/2024.1.focvid23176 Negative / Null Result ReportOpen accessMedicine
Story BD, Thomasy SM, Randolph MW et al. · 2024 · Frontiers in veterinary science
Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population. The hallmark…
View details →DOI: 10.3389/fvets.2024.1479363 Negative / Null Result ReportOpen accessMedicine
Sood M, Hegde V, Prabhu N et al. · 2026 · Journal of Indian Prosthodontic Society
Aim This study aimed to assess the shear bond strength between three-dimensional (3D)-printed acrylic denture base resin and 3D-printed teeth with and without ridge lap surface modifications. Materials and methods The investigation…
View details →DOI: 10.4103/jips.jips_423_25 Negative / Null Result Report
Li W, Shi M, Zhou P et al. · 2024 · Preprint
Background: The outcome of extramedullary infiltration (EMI) in pediatric acute myeloid leukemia (AML) is controversial, and little is known about the implications of stem cell transplantation (SCT) and gemtuzumab ozogamicin (GO) treatment…
View details →DOI: 10.22541/au.171224063.38031536/v1 Negative / Null Result ReportMedicine
Gass R, Plachi F, Silva FOB et al. · 2025 · Respiratory physiology & neurobiology
Excess exercise ventilation (high ventilation (V̇ E )/carbon dioxide output (V̇CO 2 )) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective…
View details →DOI: 10.1016/j.resp.2024.104359 