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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19847 results in Negative / Null Result Report · page 317 of 662

Negative / Null Result ReportOpen accessMedicine

Dimensional Stability of SLA 3D-Printed Surgical Guide Resin After Steam Sterilization (121 °C and 134 °C) and Isopropyl Alcohol Disinfection: An In Vitro Study.

Sîrbu I, Custura A, Radu A et al. · 2026 · Dentistry journal

Background : Additively manufactured surgical guides require post-processing and subsequent decontamination prior to intraoral use. Steam sterilization and chemical disinfection protocols may influence the dimensional stability of…

View details →DOI: 10.3390/dj14040204
Negative / Null Result Report

The influence of verbalization versus imagery on trauma memory

Rupietta AE, Meyer T, Margraf J et al. · 2025 · Preprint

Background: Cognitive theories on trauma memory postulate that trauma-related intrusions are associated with more data-driven and less contextual processing. However, contextualisation can be enhanced via verbalization, suggesting that…

View details →DOI: 10.31234/osf.io/tcsre_v2
Negative / Null Result ReportMedicine

Effects of hypocaloric wholegrain rye vs refined wheat diets on weight loss, cardiometabolic risk factors and gut microbiota: A 12-week randomized controlled trial.

Åberg S, Nordin E, Iversen KN et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)

Background and aims Wholegrain rye foods have shown promising effects on metabolic regulation and weight-loss, which may be mediated via gut microbiota and derived metabolites. This study aimed to investigate effects of hypocaloric diets…

View details →DOI: 10.1016/j.clnu.2026.106618
Negative / Null Result ReportMedicine

Stability strategy restrictions do not elicit compensatory mechanisms during mediolaterally perturbed slow walking.

Best AN, Vlutters M, Wu AR · 2025 · IEEE transactions on bio-medical engineering

Objective Healthy individuals have the ability to overcome perturbations when walking without falling. They have multiple stability strategies at their disposal, but it remains unclear how these different strategies compensate for one…

View details →DOI: 10.1109/tbme.2025.3630549
Negative / Null Result ReportMedicine

Transmucosal detomidine gel induces emesis in approximately half of cats presenting for dietary indiscretion.

Neufeld MR, Hanson KR, Mochel JP et al. · 2026 · Journal of the American Veterinary Medical Association

Objective To evaluate the efficacy and safety of transmucosal administration of detomidine gel to induce emesis in cats. Methods Cats presenting on an emergency basis due to dietary indiscretion were eligible for enrollment at 2 emergency…

View details →DOI: 10.2460/javma.25.10.0644
Negative / Null Result ReportOpen accessMedicine

Unplanned hospital presentations in oncology patients receiving chemotherapy: a secondary analysis of a randomized controlled trial to explore opportunities for improving supportive care.

Kim B, Boustany C, Fethney J et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Purpose This study aimed to report the incidence, common reasons, and associated risk factors for unplanned hospital presentations during chemotherapy treatment. Methods A secondary analysis using data from a randomized controlled trial…

View details →DOI: 10.1007/s00520-026-10510-7
Negative / Null Result ReportMedicine

Acute dysfunction of granular-based anaerobic reactor triggered by short-term exposure to colloid-containing wastewater: from irreversible sludge flotation to systemic failure.

Xie L, Lian H, Yin H et al. · 2026 · Bioresource technology

Inert colloidal substances (ICS) are ubiquitous in industrial wastewater; however, their effects on the stability of anaerobic granular sludge beds remain insufficiently understood. Using polyacrylamide as a model ICS, this study…

View details →DOI: 10.1016/j.biortech.2025.133919
Negative / Null Result ReportMedicine

Efficacy and safety of cannabidiol oil in psoriasis: a randomized, double-blind, placebo-controlled trial.

Roongpisuthipong W, Klangjareonchai T, Kurathong S et al. · 2026 · The Journal of dermatological treatment

Background The management of psoriasis presents challenges, prompting many patients to seek alternative treatments. Cannabidiol (CBD) has demonstrated potential antioxidant and anti-inflammatory properties which may offer therapeutic…

View details →DOI: 10.1080/09546634.2025.2604448
Negative / Null Result ReportOpen accessMedicine

Case Report: Telitacicept exposure in early pregnancy in a patient with SLE delivering an infant without any physical defect.

Huang XS, He ZY, Wang SG et al. · 2025 · Frontiers in medicine

Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterized by inflammatory damage to multiple organs. Its incidence rate is relatively high among women of childbearing age. The use of biologics is not…

View details →DOI: 10.3389/fmed.2025.1737355
Negative / Null Result ReportMedicine

Effects of ultralow oxygen treatments at low temperature on survival of spotted wing drosophila, Drosophila suzukii (Diptera: Drosophilidae), in blueberries and sweet cherries.

Liu YB · 2025 · Journal of economic entomology

Controlled atmosphere with ultralow oxygen (ULO) treatments were conducted to determine effects against eggs and larvae of spotted wing drosophila, Drosophila suzukii (Diptera: Drosophilidae), in blueberries and cherries at 3 °C in 19…

View details →DOI: 10.1093/jee/toaf259
Negative / Null Result ReportMedicine

Administration of EAPCI patient video animation versus standard patient information leaflets in the catheterization laboratory: Impact on patient experience assessed using the PATCATH questionnaire.

Rai H, Byrne KK, O'Callaghan D et al. · 2026 · Cardiovascular revascularization medicine : including molecular interventions

Background The Patient Experience in the Catheterization Laboratory (PATCATH) Questionnaire was developed by the European Association of Percutaneous Cardiovascular Intervention (EAPCI) to evaluate patient understanding of coronary…

View details →DOI: 10.1016/j.carrev.2026.01.004
Negative / Null Result ReportMedicine

Effects of Exercise and Intensive Vascular Risk Reduction on Cognitive Function in Older Adults: A Randomized Clinical Trial.

Zhang R, Vidoni E, Vongpatanasin W et al. · 2026 · JAMA neurology

Importance Physical inactivity, hypertension, and hyperlipidemia are modifiable cardiovascular risk factors for age-related cognitive decline and dementia. It remains unknown whether exercise training combined with intensive…

View details →DOI: 10.1001/jamaneurol.2026.0359
Negative / Null Result ReportMedicine

Identification of immune cell subsets involved in retinal ganglion cell damage following blast exposure.

Harper MM, Jones MG, Gramlich OW et al. · 2026 · Experimental eye research

Traumatic brain injury from blast exposure (bTBI) has been shown to cause functional and structural retinal ganglion cell (RGC) damage. Previous studies have shown the immune system is activated following blast exposure and that adoptive…

View details →DOI: 10.1016/j.exer.2026.110961
Negative / Null Result ReportMedicine

Cavernous ganglioneuroma of the thoracic spine: surgical nuances and outcomes following limited anterior resection.

Yılmaz MC, Tezer P, Olgaç G et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Background Spinal tumors constitute approximately 15% of all primary central nervous system neoplasms, with extradural tumors accounting for the majority. Ganglioneuromas are rare, benign tumors of neural crest origin, most often located…

View details →DOI: 10.1007/s00586-025-09711-1
Negative / Null Result Report

Silicon Application in the Plant–Insect Interaction Between Cowpea Genotypes and the Black Aphid Aphis craccivora (Hemiptera: Aphididae)

Morais JVS, Oliveira TRd, Moura ACMd et al. · 2026 · Preprint

Cowpea (Vigna unguiculata) is a crop of major socioeconomic importance in Northern and Northeastern Brazil, but its productivity is strongly constrained by infestations of the black aphid Aphis craccivora, which causes direct damage…

View details →DOI: 10.20944/preprints202601.1154.v1
Negative / Null Result ReportMedicine

The effect of autologous platelet-rich plasma on donor site wound healing: a randomised crossover clinical trial.

Dasmeh U, Mohammadi AA, Shahrokhi R et al. · 2025 · Journal of wound care

Objective This study aimed to investigate whether application of autologous platelet-rich plasma (PRP) at split-thickness skin grafting (STSG) donor sites in patients with burns can promote wound healing. Method A randomised crossover…

View details →DOI: 10.12968/jowc.2023.0210
Negative / Null Result ReportMedicine

Dry Needling Plus Manual Therapy and Exercise for Subacromial Pain Syndrome: A Sham-Controlled Randomized Clinical Trial.

Hando BR, Rhon DI, Barker D et al. · 2026 · The Journal of orthopaedic and sports physical therapy

OBJECTIVE: To determine the effect on Shoulder Pain and Disability Index (SPADI) scores of adding dry needling to a program of exercise and manual therapy in individuals with subacromial pain syndrome (SAPS). DESIGN: Three-arm randomized…

View details →DOI: 10.2519/jospt.2025.13460
Negative / Null Result ReportMedicine

Harvesting of peroneus longus tendon autograft

Liang C, He J · 2025 · Journal of Visualized Experiments

Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…

Negative / Null Result ReportMedicine

Prenatal and Early Intimate Partner Psychological Violence and Children's Hospital Health Care Use: The ELFE Cohort.

Bailhache M, El-Khoury F, Chazelas E et al. · 2026 · Academic pediatrics

Objective To determine the association between parental psychological intimate partner violence (IPV) before and around the time of the child's birth, and their use of an emergency department (ED) and hospitalization from 2 months to 10…

View details →DOI: 10.1016/j.acap.2026.103270
Negative / Null Result Report

Clavipectoral fascia block associated with intermediate cervical plexus block versus intermediate cervical plexus block alone in clavicle surgeries: a randomized clinical trial

Conceicao D, Helayel P, Garcia J et al. · 2025 · Preprint

Abstract Background: Midshaft clavicular fractures account for approximately 5% of bone fractures. Surgical correction is often necessary to ensure adequate functional recovery. There is no consensus in the literature on which Regional…

View details →DOI: 10.21203/rs.3.rs-5327123/v1
Negative / Null Result ReportMedicine

Effect of Local Cold Application on Nausea and Vomiting in Early Postoperative Period-A Randomized Controlled Trial.

Türkiş NA, Taşdemir N · 2026 · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

Purpose Postoperative nausea and vomiting (PONV) is one of the most common complications in surgical patients during the first 24 hours after general anesthesia. This research aimed to evaluate the effect of cold application on early PONV…

View details →DOI: 10.1016/j.jopan.2025.06.003
Negative / Null Result ReportMedicine

Cytogenotoxic effects of polycyclic aromatic hydrocarbons complex mixture in human peripheral blood, lung A549 and liver HepG2 cells: Translation of a real-scenario exposure to in vitro.

Kazensky L, Lovrić Štefiček MJ, Kašuba V et al. · 2026 · Environmental research

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous air pollutants, where their genotoxic potential raises significant public health concerns. This study evaluated the cytotoxic and genotoxic effects of an environmentally relevant…

View details →DOI: 10.1016/j.envres.2026.124252
Negative / Null Result ReportMedicine

Using self-tailored deposit contracts and reinforcement thinning to increase physical activity of sedentary adults.

McCullen MN, Zerger HM · 2025 · Journal of applied behavior analysis

Previous research supports behavioral interventions, such as contingency management, to increase physical activity. A common limitation of these interventions is a lack of maintenance effects or assessment of the target behavior following…

View details →DOI: 10.1002/jaba.70032