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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21173 results · page 30 of 706

Negative / Null Result ReportSocial Sciences

Computational Journalism in Norwegian Newsrooms

Joakim Karlsen, Eirik Stavelin · 2013 · Journalism Practice

This article examines computational journalism as a craft practised in Norwegian newsrooms. Based on in-depth interviews with expert practitioners in six of the largest newsrooms in Norway, we find that computational journalism represents…

View details →DOI: 10.1080/17512786.2013.813190Cited by 189
Negative / Null Result ReportOpen accessSocial Sciences

Bending the Pipeline? Executive Search and Gender Inequality in Hiring for Top Management Jobs

Isabel Fernandez‐Mateo, Roberto M. Fernandez · 2016 · Management Science

We study the sources of women’s underrepresentation in hiring for top management jobs by focusing on the context of executive search. Using data that include proprietary information on 10,970 individuals considered by a search firm, we…

View details →DOI: 10.1287/mnsc.2015.2315Cited by 189
Negative / Null Result ReportPsychology

An Assessment of the Magnitude of Effect Sizes

Ted A. Paterson, P. D. Harms, Piers Steel et al. · 2015 · Journal of Leadership & Organizational Studies

This study compiles information from more than 250 meta-analyses conducted over the past 30 years to assess the magnitude of reported effect sizes in the organizational behavior (OB)/human resources (HR) literatures. Our analysis revealed…

View details →DOI: 10.1177/1548051815614321Cited by 189
Negative / Null Result ReportOpen accessSocial Sciences

Weakening the Enemy

Hanne Fjelde, Lisa Hultman · 2013 · Journal of Conflict Resolution

While case-based narratives from civil wars often stress the ethnic dimension of civilian atrocities, cross-national studies have found limited evidence in support of such contentions. Addressing this debate, we argue that warring actors…

View details →DOI: 10.1177/0022002713492648Cited by 189
Negative / Null Result ReportOpen accessMedicine

Racial Disparities in Postpartum Pain Management

Nevert Badreldin, William A. Grobman, Lynn M. Yee · 2019 · Obstetrics and Gynecology

OBJECTIVE: To evaluate racial and ethnic differences in women's postpartum pain scores, inpatient opioid administration, and discharge opioid prescriptions. METHODS: We conducted a retrospective cohort study of all deliveries at a single…

View details →DOI: 10.1097/aog.0000000000003561Cited by 189
Negative / Null Result ReportOpen accessEnvironmental Science

Significant Difference in Hydrogen Isotope Composition Between Xylem and Tissue Water in Populus Euphratica

Liangju Zhao, Lixin Wang, Lucas A. Cernusak et al. · 2016 · Plant Cell & Environment

Deuterium depletions between stem water and source water have been observed in coastal halophyte plants and in multiple species under greenhouse conditions. However, the location(s) of the isotope fractionation is not clear yet and it is…

View details →DOI: 10.1111/pce.12753Cited by 189
Negative / Null Result ReportOpen accessMedicine

Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence

Alisa J. Prager, Nina Martinez, Kathryn Beal et al. · 2015 · American Journal of Neuroradiology

BACKGROUND AND PURPOSE: Treatment-related changes and recurrent tumors often have overlapping features on conventional MR imaging. The purpose of this study was to assess the utility of DWI and DSC perfusion imaging alone and in combination to differentiate treatment-related effects and recurrent high-grade gliomas. MATERIALS AND METHODS: We retrospectively identified 68 consecutive patients with high-grade gliomas treated by surgical resection followed by radiation therapy and temozolomide, who then developed increasing enhancing mass lesions indeterminate for treatment-related changes versus

View details →DOI: 10.3174/ajnr.a4218Cited by 189
Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Are low but statistically significant levels of genetic differentiation in marine fishes ‘biologically meaningful’? A case study of coastal Atlantic cod

Halvor Knutsen, Esben Moland Olsen, Per Erik Jorde et al. · 2010 · Molecular Ecology

A key question in many genetic studies on marine organisms is how to interpret a low but statistically significant level of genetic differentiation. Do such observations reflect a real phenomenon, or are they caused by confounding factors…

View details →DOI: 10.1111/j.1365-294x.2010.04979.xCited by 188
Negative / Null Result ReportEnvironmental Science

Dietary Cadmium Exposure and Risk of Postmenopausal Breast Cancer: A Population-Based Prospective Cohort Study

Bettina Julin, Alicja Wolk, Leif Bergkvist et al. · 2012 · Cancer Research

The ubiquitous food contaminant cadmium has features of an estrogen mimetic that may promote the development of estrogen-dependent malignancies, such as breast cancer. However, no prospective studies of cadmium exposure and breast cancer…

View details →DOI: 10.1158/0008-5472.can-11-0735Cited by 188
Negative / Null Result ReportOpen accessMedicine

Medication Use to Reduce Risk of Breast Cancer

US Preventive Services Task Force, Douglas K Owens, Karina W. Davidson et al. · 2019 · JAMA

Importance: Breast cancer is the most common nonskin cancer among women in the United States and the second leading cause of cancer death. The median age at diagnosis is 62 years, and an estimated 1 in 8 women will develop breast cancer at…

View details →DOI: 10.1001/jama.2019.11885Cited by 188
Negative / Null Result ReportBusiness, Management and Accounting

Can Electronic Procurement Improve Infrastructure Provision? Evidence from Public Works in India and Indonesia

Sean Lewis-Faupel, Yusuf Neggers, Benjamin Olken et al. · 2016 · American Economic Journal Economic Policy

This paper examines whether electronic procurement (e-procurement), which increases access to information and reduces personal interactions with potentially corrupt officials, improves procurement outcomes. We develop unique datasets from…

View details →DOI: 10.1257/pol.20140258Cited by 188
Negative / Null Result ReportMedicine

Identification of Therapeutic Benefit from Revascularization in Patients With Left Ventricular Systolic Dysfunction

Lee Fong Ling, Thomas H. Marwick, Demetrio Roland Flores et al. · 2013 · Circulation Cardiovascular Imaging

BACKGROUND: Although the recent surgical treatment of ischemic heart failure substudy reported that revascularization of viable myocardium did not improve survival, these results were limited by the viability imaging technique used and the…

View details →DOI: 10.1161/circimaging.112.000138Cited by 188
Negative / Null Result ReportMedicine

Gefitinib Plus Chemotherapy Versus Chemotherapy in Epidermal Growth Factor Receptor Mutation–Positive Non–Small-Cell Lung Cancer Resistant to First-Line Gefitinib (IMPRESS): Overall Survival and Biomarker Analyses

Tony Mok, Sang‐We Kim, Yi‐Long Wu et al. · 2017 · Journal of Clinical Oncology

Purpose The Iressa Mutation-Positive Multicentre Treatment Beyond ProgRESsion Study (IMPRESS) compared the continuation of gefitinib plus chemotherapy with placebo plus chemotherapy in patients with epidermal growth factor receptor ( EGFR)…

View details →DOI: 10.1200/jco.2017.73.9250Cited by 187
Negative / Null Result ReportOpen accessMedicine

Incidence of Extraarticular Rheumatoid Arthritis in Olmsted County, Minnesota, in 1995–2007 Versus 1985–1994: A Population-based Study

Elena Myasoedova, Cynthia S. Crowson, Carl Turesson et al. · 2011 · The Journal of Rheumatology

OBJECTIVE: To assess incidence and mortality effects of extraarticular rheumatoid arthritis (ExRA) in patients with incident RA in 1995-2007 compared to 1985-1994, in Olmsted County, Minnesota, USA. METHODS: Data on incident ExRA were…

View details →DOI: 10.3899/jrheum.101133Cited by 187
Negative / Null Result ReportOpen accessMedicine

Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury

Benjamin Gravesteijn, Daan Nieboer, Ari Ercole et al. · 2020 · Journal of Clinical Epidemiology

OBJECTIVE: We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. STUDY DESIGN AND SETTING: We performed logistic regression (LR), lasso…

View details →DOI: 10.1016/j.jclinepi.2020.03.005Cited by 187
Negative / Null Result ReportOpen accessEnvironmental Science

Aridity drove the evolution of extreme embolism resistance and the radiation of conifer genusCallitris

Maximilian Larter, Sebastian Pfautsch, Jean‐Christophe Domec et al. · 2017 · New Phytologist

Summary Xylem vulnerability to embolism is emerging as a major factor in drought‐induced tree mortality events across the globe. However, we lack understanding of how and to what extent climate has shaped vascular properties or functions.…

View details →DOI: 10.1111/nph.14545Cited by 186
Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology

The Impact of Population Demography and Selection on the Genetic Architecture of Complex Traits

Kirk E. Lohmueller · 2014 · PLoS Genetics

Population genetic studies have found evidence for dramatic population growth in recent human history. It is unclear how this recent population growth, combined with the effects of negative natural selection, has affected patterns of deleterious variation, as well as the number, frequency, and effect sizes of mutations that contribute risk to complex traits. Because researchers are performing exome sequencing studies aimed at uncovering the role of low-frequency variants in the risk of complex traits, this topic is of critical importance. Here I use simulations under population genetic models

View details →DOI: 10.1371/journal.pgen.1004379Cited by 186
Negative / Null Result ReportOpen accessComputer Science

Training generative neural networks via Maximum Mean Discrepancy optimization

Gintare Karolina Dziugaite, Daniel M. Roy, Zoubin Ghahramani · 2015 · arXiv (Cornell University)

We consider training a deep neural network to generate samples from an unknown distribution given i.i.d. data. We frame learning as an optimization minimizing a two-sample test statistic---informally speaking, a good generator network…

View details →DOI: 10.48550/arxiv.1505.03906Cited by 186
Negative / Null Result ReportOpen accessEnvironmental Science

To feed or not to feed? Evidence of the intended and unintended effects of feeding wild ungulates

Jos M. Milner, Floris M. van Beest, Karoline T. Schmidt et al. · 2014 · Journal of Wildlife Management

ABSTRACT Ungulate populations are important natural resources, associated with both costs and benefits. Conflicts have arisen between stakeholders who benefit from high ungulate numbers and those faced with the costs. Supplementary or…

View details →DOI: 10.1002/jwmg.798Cited by 186
Negative / Null Result ReportSocial Sciences

Meerkat and Periscope

John Tang, Gina Venolia, Kori Inkpen · 2016

We conducted a mixed methods study of the use of the Meerkat and Periscope apps for live streaming video and audio broadcasts from a mobile device. We crowdsourced a task to describe the content, setting, and other characteristics of 767…

View details →DOI: 10.1145/2858036.2858374Cited by 186
Negative / Null Result ReportEconomics, Econometrics and Finance

Short Selling Around Seasoned Equity Offerings

Tyler R. Henry, Jennifer L. Koski · 2010 · Review of Financial Studies

We use daily short-selling data to examine whether short selling around seasoned equity offerings (SEOs) reflects informed or manipulative trading. Around SEO announcements, we find no evidence of informed short selling. Around issue…

View details →DOI: 10.1093/rfs/hhq076Cited by 186
Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Phylogenomic analysis sheds light on the evolutionary pathways towards acoustic communication in Orthoptera

Hojun Song, Olivier Béthoux, Seunggwan Shin et al. · 2020 · Nature Communications

Acoustic communication is enabled by the evolution of specialised hearing and sound producing organs. In this study, we performed a large-scale macroevolutionary study to understand how both hearing and sound production evolved and affected diversification in the insect order Orthoptera, which includes many familiar singing insects, such as crickets, katydids, and grasshoppers. Using phylogenomic data, we firmly establish phylogenetic relationships among the major lineages and divergence time estimates within Orthoptera, as well as the lineage-specific and dynamic patterns of evolution for hea

View details →DOI: 10.1038/s41467-020-18739-4Cited by 185
Negative / Null Result ReportOpen accessEnvironmental Science

Cascading effects of artificial light at night: resource-mediated control of herbivores in a grassland ecosystem

Jonathan Bennie, Thomas W. Davies, David Cruse et al. · 2015 · Philosophical Transactions of the Royal Society B Biological Sciences

Artificial light at night has a wide range of biological effects on both plants and animals. Here, we review mechanisms by which artificial light at night may restructure ecological communities by modifying the interactions between species. Such mechanisms may be top-down (predator, parasite or grazer controlled), bottom-up (resource-controlled) or involve non-trophic processes, such as pollination, seed dispersal or competition. We present results from an experiment investigating both top-down and bottom-up effects of artificial light at night on the population density of pea aphids Acyrthosi

View details →DOI: 10.1098/rstb.2014.0131Cited by 185
Negative / Null Result ReportOpen accessSocial Sciences

The effectiveness of short‐format refutational fact‐checks

Ullrich K. H. Ecker, Ziggy O’Reilly, Jesse S. Reid et al. · 2019 · British Journal of Psychology

Fact-checking has become an important feature of the modern media landscape. However, it is unclear what the most effective format of fact-checks is. Some have argued that simple retractions that repeat a false claim and tag it as false…

View details →DOI: 10.1111/bjop.12383Cited by 185
Negative / Null Result ReportEnvironmental Science

The role of mosses in ecosystem succession and function in Alaska’s boreal forestThis article is one of a selection of papers from The Dynamics of Change in Alaska’s Boreal Forests: Resilience and Vulnerability in Response to Climate Warming.

Merritt R. Turetsky, Michelle C. Mack, Teresa N. Hollingsworth et al. · 2010 · Canadian Journal of Forest Research

Shifts in moss communities may affect the resilience of boreal ecosystems to a changing climate because of the role of moss species in regulating soil climate and biogeochemical cycling. Here, we use long-term data analysis and literature…

View details →DOI: 10.1139/x10-072Cited by 185
Negative / Null Result ReportOpen accessMedicine

Preventive or Deferred Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy and Implantable Defibrillator (BERLIN VT)

Stephan Willems, Roland Richard Tilz, Daniel Steven et al. · 2020 · Circulation

Background: Catheter ablation for ventricular tachycardia (VT) reduces the recurrence of VT in patients with implantable cardioverter-defibrillators (ICDs). The appropriate timing of VT ablation and its effects on mortality and heart…

View details →DOI: 10.1161/circulationaha.119.043400Cited by 185
Negative / Null Result ReportOpen accessBusiness, Management and Accounting

Climate-risk materiality and firm risk

Ella Mae Matsumura, Rachna Prakash, Sandra C. Vera‐Muñoz · 2022 · Review of Accounting Studies

Abstract Managers are required to disclose material climate risk in Form 10-K, but their decision whether or not to disclose is confounded by the lack of consensus on whether climate risk is material to the firms, as well as uncertainty about enforcement of disclosure regulations. Using the SASB Materiality Map™ to proxy for market expectations of climate risk materiality, we test whether the association between disclosing climate risk in 10-Ks and firm risk (proxied by cost of equity (COE)) varies with market expectations of climate risk materiality. Using S&P 500 firms’ decisions whether

View details →DOI: 10.1007/s11142-022-09718-9Cited by 184
Negative / Null Result ReportEconomics, Econometrics and Finance

Green innovation and ecological footprint relationship for a sustainable development: Evidence from top 20 green innovator countries

Ahmet Köseoğlu, Ali Gökhan Yücel, Recep Ulucak · 2022 · Sustainable Development

Abstract The ecological pressure of humanity on the planet measured by ecological footprint has been enlarging, which upsurges environmental threats. At this point, green innovation emerges as an optimal solution to sustainable development…

View details →DOI: 10.1002/sd.2294Cited by 184
Negative / Null Result ReportOpen accessMedicine

DPYD Variants as Predictors of 5-fluorouracil Toxicity in Adjuvant Colon Cancer Treatment (NCCTG N0147)

Adam M. Lee, Qian Shi, Emily S. Pavey et al. · 2014 · JNCI Journal of the National Cancer Institute

BACKGROUND: Previous studies have suggested the potential importance of three DPYD variants (DPYD*2A, D949V, and I560S) with increased 5-FU toxicity. Their individual associations, however, in 5-FU-based combination therapies, remain…

View details →DOI: 10.1093/jnci/dju298Cited by 184