A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21287 results · page 284 of 710
Beerse M, Bigelow KE, Barrios JA · 2025 · Exp Brain Res
The uncontrolled manifold analysis (UCM) is a useful technique for motor learning research enabling the classification of movement variability into solutions and errors. Less explored methodological considerations within the UCM framework…
Raynaud Q, Dardano T, Oliveira R et al. · 2026 · NMR in biomedicine
Maps of the transverse relaxation rate R 2 * and magnetic susceptibility (χ) are computed from gradient-echo data and are sensitive to signal instabilities induced by cardiac pulsation. Here, we introduce two k-space sampling strategies…
Santoro S, Mota FC, de Aquino CGG et al. · 2025 · Updates in surgery
To present and analyze the results of sleeve gastrectomy with transit bipartition (SG + TB) with three different lengths of common channel (CC) and its implications for the weight loss and signals of residual malabsorption. A total of 790…
Shu W, Wan J, Xu H et al. · 2025 · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Background Although previous studies have shown the potential advantages of albumin administration in critically ill patients, it has not been tested in patients with severe acute pancreatitis. Methods In this single-center trial, we…
Uhrbrand CG, Carlé N, Valancius K et al. · 2025 · Spine
Study design A randomized blinded trial with three groups. Objective To evaluate whether a single intraoperative methadone dose reduces postoperative opioid requirements and pain intensity in patients undergoing lumbar fusion surgery.…
Nageswaran S, Easterling D, Skaar JE et al. · 2025 · Pediatrics
Background and objectives Improving home health (HH) care for children with medical complexity (CMC) is critical. We developed ICollab, a care model involving collaboration between a children's hospital's complex care clinicians, HH…
Nahmias J, Stopenski S, Jebbia M et al. · 2025 · JAMA surgery
Importance Traumatic rib fractures are associated with significant morbidity, including pulmonary complications and prolonged opioid use. Identifying adjunctive treatments that can reduce opioid consumption without compromising safety…
Cariou B, Thys A, Oliveira AR et al. · 2025 · Diabetes, obesity & metabolism
Aims Postprandial hyperlipidaemia (PPL), characterized by elevated triglyceride (TG) concentrations after a meal, is common in type 2 diabetes (T2D) and is often recognized as an independent cardiovascular risk factor. Here, we aimed to…
Wynberg E, Mishra A, Liverani M et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Poorly targeted antibiotic use in primary care is a driver of antimicrobial resistance. Electronic clinical decision support algorithms (eCDSAs) integrating point-of-care tests may improve prescribing. We evaluated the impact of…
Larsen M, Underdal M, Salvesen Ø et al. · 2025 · Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
Objective Long latent phase of labor with subsequent prolonged total labor duration increases the risk of obstetric interventions and complications. We explored whether Proactive Support of Labor (PSL) compared to Standard Support of Labor…
Rana V, Singh GK · 2026 · Preprint
Abstract Police personnel carry an elevated burden of common mental disorders, yet low mental health literacy (MHL) and stigma constrain help-seeking and brief, content-validated MHL interventions for police in low and middle-income…
Idoudi S, Hassan AF, Kheraldine H et al. · 2026 · Scientific reports
Ketamine (KET) exhibits potential anticancer activity, with enhanced cytotoxicity against melanoma cells when combined with the permeation enhancer dodecyl maltoside (DDM). To support clinical translation, this study evaluated the…
Griffin AJ, Jungers JM · 2025 · Field Crops Research.
Intermediate wheatgrass (Thinopyrum intermedium; IWG) is a perennial, cool-season grass undergoing domestication as a grain and forage crop. Intercropping perennial legumes with IWG could reduce synthetic N fertilizer inputs, improve…
Moraes LGDS, Oliveira VC, Macedo AP et al. · 2025 · The International journal of prosthodontics
Purpose To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus,…
saboul H, Lesage V, Beernaert L et al. · 2025 · Preprint
Abstract Methods: A prospective randomized trial was conducted from October 26, 2022, to September 15, 2023, involving 101 patients randomized into two groups: the interventional group received POCUS (pulmonary and inferior vena cava…
Davila-Piñón P, Díez Martín AI, Nogueira-Rodríguez A et al. · 2025 · Preprint
Background: /Objectives: Computer-aided detection (CADe) systems are increasingly used in endoscopy to enhance lesion recognition. PolyDeep is a CADe/x tool previously assessed in an observational study. The aim of our study is to…
Bouman Z, De Vries F, De Ruiter M et al. · 2026 · Endoscopy international open
Background and study aims Esophagogastroduodenoscopy is a widely used medical examination. Despite the short duration of this procedure, many patients experience anxiety, pain, and discomfort. The aim of this study was to examine effects…
García-García M, Mosqueda J, Escobar-Cabrera JE et al. · 2025 · Toxicon : official journal of the International Society on Toxinology
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
Belak L, James K, Auguste L et al. · 2026 · Preprint
ABSTRACT Background Hypertension is a leading modifiable cardiovascular risk factor prominently influenced by health-related social needs (HRSN). Whether detailed information on HRSN can improve identification of hypertension among…
Baumann AN, Chatzis K, Son E et al. · 2026 · Spine
Study design Retrospective single-center study. Objective We aim to compare the prognostic capacity of postoperative T4-L1PA mismatch versus T4PA and L1PA alone. Summary of background data The assessment of T4-L1PA mismatch, the difference…
Li YH, Cheng YC, Chang CY et al. · 2026 · Diagnostics (Basel, Switzerland)
Objectives: Multimodal large language models (MLLMs) have shown potential for medical image classification. We evaluated four optimization strategies in two MLLMs-GPT-4o (gpt-4o-2024-08-06) and Gemini 2.5 Flash-Lite-for ultrasound-based…
Singhal M, Nidadavole K, Murphy DS et al. · 2026 · Journal of pharmaceutical sciences
Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this case study, an immediate-release tablet of an investigational BCS Class II compound exhibited slow and…
Smith HJ, Delf B, Rosi V et al. · 2026 · Preprint
Artificial voices are encountered frequently in modern life, including artificial “clones” of an individual’s voice. For natural voices, familiar talkers are more intelligible than unfamiliar talkers when competing speech is present, which…
Dolak KD, Davila S, White PC · 2026 · BMC pediatrics
Background Procalcitonin is a useful screen for bacterial infection, but its utility in pediatric diabetic ketoacidosis (DKA) is unknown. Methods We conducted a retrospective study of DKA patients admitted to two pediatric hospitals in…
Kobas B, Koth SC, Reitmayer A et al. · 2026 · Preprint
Abstract Continuous mechanical cooling is commonly used to maintain thermal comfort in office environments; however, its influence on human thermophysiological adaptation under sedentary conditions remains poorly understood. This study…
Drake C, Buckman C, Brucker A et al. · 2026 · JAMA internal medicine
Importance Patients with diabetes and food insecurity are at greater risk of adverse health outcomes. Effective strategies to promote healthy food access are urgently needed. Objective To evaluate the effect of a produce prescription (PRx)…
Tamás S, György H, András M et al. · 2026 · The international journal of lower extremity wounds
IntroductionThe treatment of chronic non-healing wounds represents a great challenge in healthcare, especially in rehabilitation medicine, as it contributes significantly to increased patient mortality and morbidity. Various types of laser…
Bellesis A, Li X, Moore-Frederick D et al. · 2026 · Preprint
Summary Immortalized cell lines are widely used in biological research despite their known differences from their tissues and cell types of origin. Such cell lines are especially popular for testing hypotheses regarding the activity of cis…
Anfosso M, Schubert M, Cremers JF et al. · 2026 · Andrology
Background Non-obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility-preserving…
jannatipour p · 2026 · Preprint
Abstract Human time reproduction is systematically biased by duration, context, and recent experience, yet it remains unclear whether trial-level neural state explains residual timing error beyond this behavioral structure. Here we tested…