Negative / Null Result ReportOpen accessMedicine
Sato R, Takasaka N, Hosaka Y et al. · 2025 · BMC infectious diseases
Background The T-SPOT.TB assay is widely used for the adjunctive diagnosis of tuberculosis (TB). However, clinicians often encounter false-negative T-SPOT.TB results. The extent of TB spread may influence host immune functions, which can…
View details →DOI: 10.1186/s12879-025-10777-x Negative / Null Result ReportOpen accessMedicine
Sripa J, Suebsamran P, Pangjit K · 2026 · BMC infectious diseases
Background Opisthorchiasis remains an important public health problem in Southeast Asia and is strongly associated with cholangiocarcinoma. Although stool-based diagnosis is widely used, its sensitivity is limited in light infections,…
View details →DOI: 10.1186/s12879-026-13445-w Negative / Null Result ReportOpen accessMedicine
Unubol N, Ayaş M, Uyar NY et al. · 2025 · Microorganisms
In recent years, the World Health Organization has highlighted biofilm-derived multidrug-resistant bacteria as a critical threat to both global health and the environment. Although various testing methods are available, crystal violet and…
View details →DOI: 10.3390/microorganisms14010021 Negative / Null Result Report
AL-Saeedi A, Abdulamir AS, Aufi IM et al. · 2025 · Preprint
Abstract Background The widespread use of accurate real-time RT-PCR tests for community individuals is a critical approach to managing the disease and reducing COVID-19 transmission effectively. In addition, serological ELISA assays are…
View details →DOI: 10.21203/rs.3.rs-8233598/v1 Negative / Null Result ReportOpen accessMedicine
Mukherjee S, Fujiwara Y, Fountzilas C et al. · 2025 · Cancer medicine
Background Preoperative chemoradiation (CRT) followed by surgery for localized esophageal and gastroesophageal junction adenocarcinoma (EGAC) is a standard of care with a pathologic complete response (pCR) rate of 20%. We evaluated a novel…
View details →DOI: 10.1002/cam4.70835 Negative / Null Result ReportMedicine
Fu Q, Chen Y, Huang D et al. · 2023 · Annals of surgical oncology
Background Folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or modified FOLFIRINOX (mFFX) is the first-line standard of care for metastatic pancreatic adenocarcinoma; effective and safe treatment strategies are needed…
View details →DOI: 10.1245/s10434-023-13383-w Negative / Null Result ReportMedicine
Hiester A, Che Y, Lusch A et al. · 2023 · European urology
Background Primary retroperitoneal lymph node dissection (RPLND) for clinical stage (CS) IIA/B seminoma without adjuvant treatment is an experimental treatment to avoid radiotherapy- or chemotherapy-related toxicity from standard…
View details →DOI: 10.1016/j.eururo.2022.10.021 Negative / Null Result ReportMedicine
Uyanık G, Yüksel M, Abay M et al. · 2026 · Veterinary journal (London, England : 1997)
The present study aimed to determine the diagnostic accuracy of the commercial Alertys OnFarm Pregnancy Test (AOPT) based on pregnancy-associated glycoprotein (PAG) for early pregnancy diagnosis in ewes. A total of 100 multiparous Awassi…
View details →DOI: 10.1016/j.tvjl.2026.106584 Negative / Null Result ReportOpen accessMedicine
Zhang J, Hu Y, Dong P et al. · 2025 · Diagnostics (Basel, Switzerland)
Sarcoidosis is a rare multisystem inflammatory disease characterized by non-necrotizing granulomas, typically affecting the lungs, lymph nodes, skin, and bones. Due to its extreme clinical heterogeneity, diagnosis remains challenging.…
View details →DOI: 10.3390/diagnostics15091135 Negative / Null Result ReportOpen accessMedicine
Pandey P, Bir R, Chatterjee K et al. · 2026 · Iranian journal of microbiology
Background and objectives Sepsis is a life threatening condition caused by a dysregulated host response to infection and is associated with high morbidity and mortality worldwide. Early bacterial detection and therapy with antibiotics…
View details →DOI: 10.18502/ijm.v18i3.21654 Negative / Null Result ReportOpen accessMedicine
Samkange A, Chitanga S, Mbiri P et al. · 2025 · The Onderstepoort journal of veterinary research
Neosporosis is a leading cause of bovine abortions worldwide, with a substantial economic impact because of reproductive losses, costing the cattle industry billions of dollars annually. Despite the global significance of Neospora caninum,…
View details →DOI: 10.4102/ojvr.v92i1.2237 Negative / Null Result ReportOpen accessMedicine
Lis K · 2025 · Life (Basel, Switzerland)
Vitamin B1 (thiamine) is a water-soluble B vitamin. As a cofactor of many enzymes, it is essential for the proper functioning of many body systems and organs, including metabolic and energy metabolism. In extreme cases, vitamin B1…
View details →DOI: 10.3390/life16010050 Negative / Null Result ReportMedicine
Steinhauer R, Kübler E, Gaugler S et al. · 2026 · Journal of virological methods
Dried blood spots (DBS) constitute a stable, cost-efficient sampling matrix that can be collected in a minimally invasive manner. Although widely adopted in human medicine, their use in veterinary diagnostics remains limited. This study…
View details →DOI: 10.1016/j.jviromet.2025.115336 Negative / Null Result ReportOpen accessMedicine
Rodrigues NJL, França DA, Menozzi BD et al. · 2026 · Pathogens (Basel, Switzerland)
Comparative evaluations of different serological methods for the diagnosis of toxoplasmosis in pregnant women remain limited, and the performance of indirect immunofluorescence assay (IFA), modified agglutination test (MAT), and…
View details →DOI: 10.3390/pathogens15040363 Negative / Null Result ReportMedicine
Lubberink M, Åhlström A, Tolvanen T et al. · 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Purpose Previously published effective dose coefficient estimates for 15 O-water are around 1 μSv/MBq, resulting in an effective dose of around 0.4 mSv for a typically injected activity of 400 MBq in clinical cardiac scans. These estimates…
View details →DOI: 10.1016/j.nuclcard.2026.102775 Negative / Null Result ReportMedicine
Cloonan MR, Maginot ER, Tieken KR et al. · 2026 · Journal of surgical education
To determine the frequency of nontechnical skills (NTS) feedback provided by attending surgeons through narrative comments and assess its effectiveness using a validated formative feedback rubric. This retrospective cross-sectional study…
View details →DOI: 10.1016/j.jsurg.2026.104035 Negative / Null Result ReportOpen accessMedicine
Huang J, Ye H, Lin J et al. · 2026 · PloS one
Background The cost-effectiveness of liposome irinotecan (II) (HR070803) in combination with 5-fluorouracil and leucovorin as a treatment for patients with locally advanced or metastatic pancreatic ductal adenocarcinoma offering a…
View details →DOI: 10.1371/journal.pone.0351853 Negative / Null Result ReportMedicine
Cheng X, Huang H, Fan Z et al. · 2026 · BMJ open ophthalmology
Objective To evaluate the efficacy and safety of portable, cost-effective manual thermal pulsation as a single therapy for meibomian gland dysfunction (MGD) and to compare the microbiota and lipid composition in subjects with different…
View details →DOI: 10.1136/bmjophth-2026-002769 Negative / Null Result ReportMedicine
Hayman NT, Pandelides Z, Colvin MA et al. · 2026 · Environmental toxicology and chemistry
A lack of marine specific data results in challenges to assessing site-specific ecological risks and developing marine water quality criteria for per- and polyfluoroalkyl substances (PFAS). Here, the toxicity and bioaccumulation of…
View details →DOI: 10.1093/etojnl/vgag168 Negative / Null Result ReportMedicine
De Groote W, Taremwa Y, Duttine A et al. · 2026 · International journal of environmental research and public health
In Uganda, in 2019, 6.8 million people experienced health conditions that are amenable to rehabilitation. This is largely due to musculoskeletal disorders such as low back pain (LBP). Measuring effective coverage of rehabilitation means…
View details →DOI: 10.3390/ijerph23060693 Negative / Null Result ReportMedicine
Aljuaid M, Alsiraj K · 2026 · Annals of the ICRP
This is a national study about the occupational Radiation doses for medical workers in the Kingdom of Saudi Arabia which covers the period since the establishment of the Nuclear and Radiological Regulatory Commission (NRRC). The study aims…
View details →DOI: 10.1177/01466453251411988 Negative / Null Result ReportOpen accessMedicine
Büyüksefil M, Çimen Ü, Şimşek Derelioğlu S et al. · 2026 · Oral health & preventive dentistry
Purpose Effective communication with paediatric patients is one of the cornerstones of paediatric dentistry. Strong communication skills play a critical role in reducing dental anxiety, enhancing patient satisfaction, and facilitating the…
View details →DOI: 10.3290/j.ohpd.c_2680 Negative / Null Result ReportMedicine
Choi JY, Song WS, Won YK et al. · 2026 · Korean journal of ophthalmology : KJO
Purpose To compare the effective phacoemulsification time used in cataract surgery and postoperative outcomes between the Veritas and the Centurion Vision System. Methods A retrospective analysis was conducted on 90 eyes from 82 patients…
View details →DOI: 10.3341/kjo.2025.0196 Negative / Null Result ReportMedicine
Jacobs S, Edelhoff H, Ebert C et al. · 2026 · BMC ecology and evolution
Effective population size (Ne) is a fundamental parameter in conservation genetics, providing relevant information on the adaptability and long-term viability of populations. In contrast, wildlife management strategies, particularly for…
View details →DOI: 10.1186/s12862-026-02543-7 Negative / Null Result ReportMedicine
Leung A, Koo J · 2026 · CNS drugs
Dermatological delusional disorders, such as delusional infestation (DI), are a unique type of psychosis in which the patient experiences specific delusions, such as parasites or inorganic materials that come out of their skin. Originally,…
View details →DOI: 10.1007/s40263-026-01309-5 Negative / Null Result ReportMedicine
Cherif IS, Essis EML, Diallo MA et al. · 2026 · Case reports in infectious diseases
Background Lassa fever is a potentially fatal viral hemorrhagic disease caused by a ribonucleic acid (RNA) virus of the Arenaviridae family, endemic in West Africa. It is highly virulent and contagious in several countries, with a…
View details →DOI: 10.1155/crdi/2672939 Negative / Null Result ReportMedicine
Columbo JA, Scali ST, Wanhainen A et al. · 2026 · Annals of surgery
Objective To determine the contemporary cost per quality-adjusted life year(QALY) gained for abdominal aortic aneurysm (AAA) repair in current practice and assess the optimal threshold for intervention. Summary background data The widely…
View details →DOI: 10.1097/sla.0000000000007134 Negative / Null Result ReportMedicine
Sabzehei S, Innocenti N, Rigoli M et al. · 2026 · Expert opinion on drug discovery
Introduction Prion diseases are rare, fatal neurodegenerative disorders caused by the conformational conversion of cellular prion protein (PrP) into a pathogenic counterpart called PrP Sc , that replicates by templated misfolding. The…
View details →DOI: 10.1080/17460441.2026.2688321 Negative / Null Result Report
S M, K Mk, K S · 2026 · Preprint
Abstract Industrial discharge from the textile and dyeing industries in Tamil Nadu’s Tiruppur district has severely contaminated the soil with heavy metals, posing significant ecological and human health risks. This study assesses…
View details →DOI: 10.21203/rs.3.rs-9582376/v1 Negative / Null Result ReportOpen accessMedicine
Ran X, Shang Y, Yang X et al. · 2026 · Lasers in medical science
To investigate whether noninvasive reflectance confocal microscopy (RCM)-derived vascular parameters can serve as objective predictors of therapeutic response to pulsed dye laser (PDL) treatment in patients with port wine stain (PWS),…
View details →DOI: 10.1007/s10103-026-04906-4