Negative / Null Result ReportMedicine
Guarneri C, Reschini M, Pinna M et al. · 2024 · Journal of assisted reproduction and genetics
Purpose To evaluate whether a second biopsy, following a first diagnostic failure on blastocysts tested for preimplantation genetic testing for monogenic diseases (PGT-M), allows to obtain genetic diagnosis and to what extent this…
View details →DOI: 10.1007/s10815-024-03078-w Negative / Null Result Report
Mehta SP, Antonio Aguirre B, See WYN et al. · 2025 · Preprint
Purpose Whole exome or genome sequencing (WES and WGS, respectively) can be valuable in identifying the molecular basis of inherited retinal disorders (IRD), particularly when panel-based testing yields negative or inconclusive results.…
View details →DOI: 10.1101/2025.03.03.25322102 Negative / Null Result ReportOpen accessMedicine
Su XY, Schroder A, Tse LA et al. · 2025 · BMC research notes
Background Sex hormones may play a role in the development of nasopharyngeal carcinoma (NPC), but the evidence is limited. Methods This case-control study collected information on sex hormonal and reproductive factors of 99 female incident…
View details →DOI: 10.1186/s13104-025-07471-1 Negative / Null Result Report
Khorram A · 2024 · Preprint
Abstract Introduction: To date, studies exploring shockwave-assisted orthodontic tooth movement and tooth mobility have produced inconclusive results, largely attributable to varying methodologies and a lack of standardized reporting. This…
View details →DOI: 10.21203/rs.3.rs-5280491/v1 Negative / Null Result ReportOpen accessMedicine
Rosa ML, Bordignon C, Schuch JB et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Formalin-fixed paraffin-embedded tissue is widely used in pathology and molecular diagnostics, yet its variable quality can critically influence the accuracy of sequencing-based analyses. This study investigated…
View details →DOI: 10.3390/diagnostics16111595 Negative / Null Result ReportOpen accessMedicine
Gopalaswamy R, Kumar N, Vashistha H et al. · 2023 · Frontiers in public health
Introduction Truenat MTB-RIF assay (Truenat), a nucleic acid amplification test (NAAT), is a real-time polymerase chain reaction (RT-PCR) chip-based assay that can detect Mycobacterium tuberculosis ( Mtb ) and rifampicin (RIF) drug…
View details →DOI: 10.3389/fpubh.2023.1255756 Negative / Null Result ReportMedicine
Tavelli R, Callens M, Grootaert C et al. · 2024 · Trends in Food Science & Technology.
Microplastics (MPs) contaminate the global marine and terrestrial ecosystems. This environmental contamination can enter the food chain, with MPs found in drinking water, fishery products and other food categories. Consequently, ingestion…
View details →DOI: 10.1016/j.tifs.2022.08.021 Negative / Null Result Report
Mwakibete L, Hoarau AOG, Ahyong V et al. · 2024 · Preprint
Investigations of wildlife diseases and mortality events can sometimes lead to inconclusive results due to limitations in diagnostics combined with an ever-increasing number of emerging viruses. The use of tools such as unbiased…
View details →DOI: 10.1101/2024.12.21.629921 Negative / Null Result ReportMedicine
Juutilainen J, Khan MW, Naarala J et al. · 2024 · Occupational and environmental medicine
Objectives Studies assessing the association of adult cancers with extremely low frequency (ELF) magnetic fields (MF) have provided inconclusive results, probably affected by limitations such as low exposure levels, confounding and various…
View details →DOI: 10.1136/oemed-2024-109466 Negative / Null Result Report
Jäggi T, Sato S, Gygax P · 2024 · Preprint
Recently, researchers have started to experimentally investigate the claim that the grammaticalization of the future may impact our mental representations of future events. Yet, this research has mainly focused on the perceived distance of…
View details →DOI: 10.31234/osf.io/4h8gs Negative / Null Result ReportOpen accessMedicine
Hernández-Cuellar E, Tsuchiya K, Medina-Contreras O et al. · 2025 · Journal of clinical medicine
Background/Objectives : Sepsis is a life-threatening condition characterized by an uncontrolled immune response due to systemic infections. It is responsible for millions of deaths worldwide. Although inflammasomes play an important role…
View details →DOI: 10.3390/jcm14197102 Negative / Null Result Report
Teuwen CJ, Vorstermans K, Kusurkar RA et al. · 2024 · Preprint
Interprofessional education is one of the interventions used to increase health care students’ motivation for working with older patients. Previous research about such interventions has been conducted without the use of control groups and…
View details →DOI: 10.12688/mep.19773.2 Negative / Null Result ReportMedicine
Nielsen MK, Bartholdy ID, Kristensen KS et al. · 2025 · Veterinary parasitology
Equine strongylids are ubiquitous and can cause severe health issues. Anthelmintic resistance is widely common in cyathostomin parasites, and recent studies have documented increasing incidence of resistance to the macrocyclic lactone drug…
View details →DOI: 10.1016/j.vetpar.2025.110465 Negative / Null Result ReportMedicine
MacCarrick G, Aradhya S, Bailey M et al. · 2024 · American journal of medical genetics. Part A
Molecular genetics enables more precise diagnoses of skeletal dysplasia and other skeletal disorders (SDs). We investigated the clinical utility of multigene panel testing for 5011 unrelated individuals with SD in the United States…
View details →DOI: 10.1002/ajmg.a.63646 Negative / Null Result ReportOpen accessMedicine
Karvasarski E, Park J, Savaris S et al. · 2026 · CJC open
Background Resting hemodynamic assessment of suspected pulmonary hypertension (PH) in older adults with cardiovascular risk factors may not effectively discriminate pre-capillary from post-capillary disease. Exercise right-heart…
View details →DOI: 10.1016/j.cjco.2026.02.005 Negative / Null Result ReportMedicine
Crabtree D, Seidler K, Barrow M · 2025 · Clinical nutrition ESPEN
Background and aims Epidemiological studies have associated reduced bacterial diversity and abundance and food allergy. This mechanistic review investigated the link between gut dysbiosis and food allergy with a focus on the role of…
View details →DOI: 10.1016/j.clnesp.2024.11.019 Negative / Null Result ReportMedicine
Nohales M, Coello A, Martin A et al. · 2023 · Journal of assisted reproduction and genetics
Purpose To investigate whether embryo rebiopsy increases the yield of in vitro fertilization (IVF) cycles. Methods Retrospective study including 18,028 blastocysts submitted for trophectoderm biopsy and preimplantation genetic testing for…
View details →DOI: 10.1007/s10815-023-02875-z Negative / Null Result ReportMedicine
Cummings M, Madhavan S · 2024 · Experimental brain research
Ischemic Conditioning (IC) is a procedure involving brief periods of occlusion followed by reperfusion in stationary limbs. Blood Flow Restriction with Exercise (BFR-E) is a technique comprising blood flow restriction during aerobic or…
View details →DOI: 10.1007/s00221-024-06941-5 Negative / Null Result ReportOpen accessMedicine
Salgotra M, Bharti N, Sinha V et al. · 2024 · Journal of pharmacy & bioallied sciences
Introduction Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective…
View details →DOI: 10.4103/jpbs.jpbs_233_24 Negative / Null Result ReportMedicine
Linthorst J, Nivard M, Sistermans EA · 2024 · Cell reports
The properties of cell-free DNA (cfDNA) are intensely studied for their potential as non-invasive biomarkers. We explored the effect of common genetic variants on the concentration and fragmentation properties of cfDNA using a genome-wide…
View details →DOI: 10.1016/j.celrep.2024.114799 Negative / Null Result ReportMedicine
Pham YT, Nguyen BN, Nguyen TG et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Iron is one of the essential elements for human life. Prior studies provided inconclusive results about the association between dietary iron intake and gastric cancer risk. We determined the association between dietary iron…
View details →DOI: 10.1158/1055-9965.epi-25-1167 Negative / Null Result Report
Santiago-Torner C · 2024 · Preprint
Creativity in virtual work environments and its influence on emotional exhaustion is a relationship with inconclusive results. Furthermore, autonomy, when it loses its original purpose of acting as a job resource, takes on an ambiguous…
View details →DOI: 10.20944/preprints202407.0008.v1 Negative / Null Result ReportMedicine
Pardi C, Hellberg Å, Isakson P · 2024 · Blood transfusion = Trasfusione del sangue
Background The Rh blood group system is highly complex, polymorphic, and immunogenic. The presence of RHD gene variants in RhD negative pregnant women is a challenge in fetal RHD genotyping as it may influence the antenatal management of…
View details →DOI: 10.2450/bloodtransfus.741 Negative / Null Result ReportOpen accessMedicine
Boyarchuk O, Volianska L, Smashna O et al. · 2024 · Frontiers in genetics
Introduction Developmental delay (DD) in children is often caused by genetic abnormalities, which are challenging to diagnose due to the vast genetic variability. Methods This study presents a detailed analysis of whole-exome sequencing…
View details →DOI: 10.3389/fgene.2024.1505254 Negative / Null Result ReportOpen accessMedicine
Gutowska A, Bohdan M, Radtke-Łysek A et al. · 2026 · The American journal of case reports
BACKGROUND Cardiac myxomas are the most common primary cardiac tumors in the general population but are exceedingly rare in orthotopic heart transplant recipients. Fewer than 5 cases have been reported. Their pathogenesis in the setting of…
View details →DOI: 10.12659/ajcr.949982 Negative / Null Result ReportMedicine
Mattke S, Jun H, Hanson M et al. · 2024 · The journal of prevention of Alzheimer's disease
Introduction As treatments for secondary prevention of Alzheimer's disease (AD) are being studied, concerns about their value for money have appeared. We estimate cost-effectiveness of a hypothetical screening and prevention program.…
View details →DOI: 10.14283/jpad.2024.23 Negative / Null Result ReportMedicine
Harjunen L, Östman K, Pohl P · 2025 · Disability and rehabilitation
Purpose Ronnie Gardiner Method (RGM) is a music-based movement therapy that has long been used within rehabilitation. There is a need to (1) identify the scope of the use of RGM, (2) explore potential benefits, (3) examine qualitative…
View details →DOI: 10.1080/09638288.2024.2392037 Negative / Null Result ReportOpen accessMedicine
Portillo-Gallo JH, Sánchez-González JM, Saldaña-Cruz AM et al. · 2026 · Current issues in molecular biology
Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have…
View details →DOI: 10.3390/cimb48020168 Negative / Null Result ReportOpen accessMedicine
Beissat K, Lattard V, Picard-Meyer E et al. · 2025 · PloS one
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range of animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence of new variants has…
View details →DOI: 10.1371/journal.pone.0316882 Negative / Null Result ReportOpen accessMedicine
Xie J, Jiang Y, Zhou Y et al. · 2024 · Maternal-fetal medicine (Wolters Kluwer Health, Inc.)
Objective To conduct a hierarchical classification analysis of the nonreportable results of noninvasive prenatal testing in an attempt to reduce failure rates and provide pregnant women with accurate information to alleviate their anxiety.…
View details →DOI: 10.1097/fm9.0000000000000248 