Differential effects of hypothalamic ET<sub>B</sub> receptor blockade in fever, hypolocomotion and serotonin release during systemic inflammation in male and female rats.
Alencar TS; Santos MO; Schneider VMM; Fernandes SMA; Borges AP; Guaita GO; Costa RA; Zampronio AR · 2026 · Brain research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Systemic inflammation triggers a set of physiological and behavioral changes known as sickness behavior, including fever and hypolocomotion. Previous studies demonstrated that lipopolysaccharide (LPS) induces these responses in both sexes,…
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Metadata source: Europe PMC · DOI 10.1016/j.brainres.2026.150417