Negative / Null Result ReportMedicine
Sachner L, Flynn JS, Hsu CW et al. · 2026 · Journal of pediatric psychology
Objective Children with cancer increasingly undergo germline genetic testing to identify genetic predispositions and inform clinical care options. Parents of children with pathogenic/likely pathogenic (P/LP) germline results have reported…
View details →DOI: 10.1093/jpepsy/jsaf026 Negative / Null Result ReportMedicine
Lee S, Lee J, Park D et al. · 2026 · NPJ digital medicine
Gastroesophageal reflux disease (GERD) diagnosis traditionally relies on acid exposure time (AET) obtained from 24-h multichannel intraluminal impedance-pH (MII-pH) monitoring, the gold standard for GERD diagnosis. However, a negative…
View details →DOI: 10.1038/s41746-026-02796-y Negative / Null Result ReportMedicine
Galloway NL, Sargeant GA, Powers JG et al. · 2026 · Journal of wildlife diseases
Effective wildlife disease management and research rely on trustworthy disease diagnostics. For chronic wasting disease (CWD), immunohistochemistry (IHC) is recognized as the gold standard, and ELISA is a reliable high-throughput screening…
View details →DOI: 10.7589/jwd-d-25-00164 Negative / Null Result ReportMedicine
Rincón-González AM, Galeano-Tamayo DC, Zuluaga LSD · 2025 · Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
Objective To explore the factors associated with the use of the antibiotic implicated in an adverse reaction following a negative challenge test in pediatric patients in a clinical allergology service of a health institution in Medellin.…
View details →DOI: 10.29262/ram.v72i3.1465 Negative / Null Result Report
Kilic A, Celiktas B · 2026 · Preprint
Abstract As Large Language Models (LLMs) are integrated into critical infrastructure, externally auditing their safety mechanism activation without internal access becomes essential. This paper investigates whether LLM safety refusals…
View details →DOI: 10.21203/rs.3.rs-9190463/v1 Negative / Null Result ReportMedicine
Warintaksa P, Youkhong C, Trikasemmart M et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Introduction True labor is characterized by regular uterine contractions and cervical changes. However, the precise diagnosis of the "onset" of true labor is challenging, as the examination of cervical changes requires multiple timepoints,…
View details →DOI: 10.1080/14767058.2026.2670757 Negative / Null Result ReportMedicine
Dincer M, Aydin O, Karakus V et al. · 2026 · Laboratory medicine
Introduction Electrophoresis tests are reported as negative, positive, or-rarely-as suspicious for monoclonal band (SfMB). This study aimed to determine the fate of patients with SfMB findings in long-term follow-up. Methods Patients with…
View details →DOI: 10.1093/labmed/lmag013 Negative / Null Result Report
Slade T · 2026 · Preprint
Large language models (LLMs) are increasingly deployed in academic and professional contexts where epistemic restraint, boundary recognition, and instruction adherence are as important as raw capability. However, existing evaluations…
View details →DOI: 10.22541/au.177023469.90459572/v1 Negative / Null Result ReportMedicine
Hidalgo CM, Yin LX, Bogan AW et al. · 2026 · Head and neck pathology
Purpose The uses for circulating tumor high risk human papillomavirus DNA (ctHPVDNA) in the diagnostic work-up and treatment of HPV-associated oropharyngeal squamous cell carcinoma (HPV( +)OPSCC) patients are actively being investigated.…
View details →DOI: 10.1007/s12105-026-01911-5 Negative / Null Result ReportOpen accessMedicine
Omari Y, Nohomovich B, Sallam D et al. · 2026 · Cureus
Multitarget stool DNA-fecal immunochemical testing (mt-sDNA-FIT) is validated for colorectal cancer (CRC) screening in asymptomatic, average-risk adults. However, its application in symptomatic patients represents a misuse of a screening…
View details →DOI: 10.7759/cureus.110890 Negative / Null Result ReportMedicine
Bhangu G, Greutert S, Robert-Ebadi H et al. · 2026 · Journal of thrombosis and haemostasis : JTH
Background Pregnancy and the postpartum period increase the risk of venous thromboembolism including pulmonary embolism (PE), which is an important cause of maternal morbidity and mortality. While diagnostic strategies for suspected PE in…
View details →DOI: 10.1016/j.jtha.2026.05.010 Negative / Null Result Report
Byeongsoo · 2026 · Preprint
Abstract Background. Flux balance analysis (FBA) is widely used to simulate gene essentiality in genome-scale metabolic models (GEMs), and several studies have proposed using FBA-based combination simulations to predict antibiotic synergy.…
View details →DOI: 10.21203/rs.3.rs-9398278/v1 Negative / Null Result ReportMedicine
Ten Have L, Buil JB, van Dijk K · 2026 · Medical mycology
In this article, we evaluate a possible postzone effect for the Histoplasma antigen lateral flow assay (LFA). We re-tested urine samples that were Histoplasma-positive with the LFA, both for an undiluted and diluted sample. Of the 12…
View details →DOI: 10.1093/mmy/myag007 Negative / Null Result ReportOpen accessMedicine
Safiejko K, Juchimiuk M, Pierko J et al. · 2026 · Cancers
Background: Liquid biopsy using circulating tumor DNA (ctDNA) is rapidly reshaping gastrointestinal (GI) oncology. The highest-impact applications are molecular residual disease (mRD) detection after curative-intent therapy and early…
View details →DOI: 10.3390/cancers18061014 Negative / Null Result ReportMedicine
Knasmüller S, Nersesyan A, Mišík M et al. · 2026 · Mutagenesis
We describe the impact of lifestyle related factors on the formation of micronuclei (MN) in buccal cells. It is known that consumption of alcohol and of other drugs including tobacco and other plants cause damage of the genetic material…
View details →DOI: 10.1093/mutage/geag008 Negative / Null Result ReportOpen accessMedicine
Vardanega MJ, Longo T, Aceino A et al. · 2026 · Journal of veterinary internal medicine
Vulvovaginal squamous cell carcinoma (SCC) is an uncommon neoplasm in dogs. An 11-year-old female spayed German Shepherd dog presented with a history of excessive peri-vulvar grooming and a 3 cm × 3 cm irregular mass involving the vagina…
View details →DOI: 10.1093/jvimsj/aalag116 Negative / Null Result ReportMedicine
Goubeau L, Curis E, Delavenne X et al. · 2026 · Blood advances
Phase 3 trials evaluating inhibitors of coagulation factor (F) XI and/or its activated form (FXIa) as novel anticoagulant drugs are ongoing. These agents include parenteral monoclonal antibody (abelacimab) and oral small molecules…
View details →DOI: 10.1182/bloodadvances.2026020472 Negative / Null Result Report
Limbu N, Lamsal RR, Shrestha A · 2025 · Preprint
Abstract Citrus Decline, a complex and devastating disorder caused by various biotic and abiotic factors has emerged as a significant challenge for citrus cultivation in Nepal. This study on “Prevalence and severity of citrus decline and…
View details →DOI: 10.21203/rs.3.rs-7250604/v1 Negative / Null Result ReportOpen accessMedicine
Yin J, Wang Q, Lan T et al. · 2026 · Frontiers in pediatrics
Background Copy number variants of uncertain significance (VUS-CNVs) pose significant challenges in prenatal counseling for congenital heart malformations (CHMs). Their clinical relevance remains poorly defined, particularly in the absence…
View details →DOI: 10.3389/fped.2026.1696089 Negative / Null Result Report
Kazanskii M, Golikova M, Kasianov A et al. · 2025 · Preprint
We investigated the possibility of estimating the age of ancient biological samples directly from their DNA damage profiles using supervised machine learning. Traditional dating methods such as radiocarbon dating, dendrochronology rely on…
View details →DOI: 10.1101/2025.11.09.687346 Negative / Null Result ReportOpen accessMedicine
Iwata K, Mori N, Ogasawara K · 2025 · Cureus
Introduction Noninvasive methods for assessing liver fibrosis are increasingly important for early detection of advanced liver fibrosis (ALF), particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).…
View details →DOI: 10.7759/cureus.93549 Negative / Null Result ReportOpen accessMedicine
Zych-Krekora K, Sylwestrzak O, Krekora M · 2026 · Journal of clinical medicine
Background/Objectives : Maternal rectovaginal carriage of Group B Streptococcus (GBS, Streptococcus agalactiae ) is a major risk factor for vertical transmission and early-onset neonatal infection. Intrapartum antibiotic prophylaxis…
View details →DOI: 10.3390/jcm15031113 Negative / Null Result ReportOpen accessMedicine
Galván CA, Durán R, Larco JI et al. · 2026 · Immunity, inflammation and disease
Background Accurate identification of respiratory allergen sensitization is essential for managing asthma and allergic rhinitis (AR). While Skin Prick Test (SPT) and ImmunoCAP are standard diagnostic tools, exploratory comparative data for…
View details →DOI: 10.1002/iid3.70325 Negative / Null Result ReportMedicine
Nakai Y, Onishi K, Asakawa I et al. · 2026 · The Prostate
Background Long-term clinical data evaluating oncological outcomes and patient-reported quality of life (QOL) after combining celecoxib with radiotherapy are lacking. Therefore, we aimed to assess oncological outcomes and QOL with extended…
View details →DOI: 10.1002/pros.70136 Negative / Null Result ReportOpen accessMedicine
Oshiro Y, Kawashima A, Akashi M et al. · 2026 · Tropical medicine and health
Background Giardiasis and cryptosporidiosis are often misdiagnosed by stool ova and parasite test (classical O&P). Multiplex PCR and rapid antigen immunochromatography (rapid-IC) could offer high diagnostic accuracy; however, their cost…
View details →DOI: 10.1186/s41182-026-00907-9 Negative / Null Result ReportMedicine
Espigares LF, Panadero AF, Sánchez MD et al. · 2026 · Multiple sclerosis and related disorders
Objective Accurate anti-JC virus (JCV) antibody testing is essential for progressive multifocal leukoencephalopathy (PML) risk stratification in natalizumab-treated patients. This study assessed evaluated inter-assay concordance between…
View details →DOI: 10.1016/j.msard.2026.107023 Negative / Null Result ReportOpen accessMedicine
Grynkiewicz M, Buffi NM, Fasulo V et al. · 2025 · Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques
Introduction Research results suggest that high-resolution ultrasonography (microUS) can be used to estimate the risk of prostate cancer (PCa) and identify suspicious areas, enabling precise biopsy during examination. Aim The aim of the…
View details →DOI: 10.20452/wiitm.2025.17978 Negative / Null Result Report
Amate A, Lieberman M · 2025 · Preprint
Abstract Medetomidine has recently emerged in the illicit drug supply in the United States, and lateral flow immunoassay test strips are an inexpensive and easy-to-use field screening option for detecting this highly potent sedative.…
View details →DOI: 10.21203/rs.3.rs-7716096/v1 Negative / Null Result ReportMedicine
van Rooij JLM, Wessels PH, Niers JM et al. · 2026 · The Lancet. Haematology
Background Primary CNS lymphoma is typically diagnosed by brain biopsy, a procedure with risks and diagnostic delay. Emerging cerebrospinal fluid (CSF) biomarkers, including the myeloid differentiation primary response 88 (MYD88) L265P…
View details →DOI: 10.1016/s2352-3026(26)00098-0 Negative / Null Result ReportOpen accessMedicine
Newman A, Hansel S, Gerrard G et al. · 2026 · Cancers
Background Surveillance of non-muscle-invasive bladder cancer (NMIBC) relies on cystoscopy and urine cytology, both of which have well-recognised limitations. Molecular urine assays have been developed to reduce the burden of invasive…
View details →DOI: 10.3390/cancers18101650 