A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19830 results in Negative / Null Result Report · page 239 of 661
Kvistad AL, Jespersen L, Bjoerndal JR et al. · 2026 · Preprint
Transcranial direct current stimulation (tDCS) holds the potential to affect behavior by modulating ongoing neural activity, and tDCS paired with hand motor practice can enhance motor learning. While augmenting the behavioral benefits of…
Palatini U, Dabo S, Rosa-Villegas A et al. · 2026 · Preprint
ABSTRACT Billions of people each year are at risk from infection by dengue, Zika, yellow fever, and chikungunya viruses, which are transmitted by female Aedes aegypti mosquitoes. Mosquitoes themselves are infected by these arboviruses, but…
Vojjala N, Nassar M, Nanjareddy S et al. · 2026 · Leukemia & lymphoma
Myelodysplastic syndrome (MDS) is an identified risk for both venous and arterial thromboembolism (ATE). The thrombotic risk of drugs used in MDS, such as Luspatercept and Erythropoietin-stimulating agents (ESAs), has yielded conflicting…
Rick TJ, Girard A, Topalian A et al. · 2026 · Journal of cancer survivorship : research and practice
Purpose Sexual health concerns are highly prevalent and distressing among adolescent and young adult (AYA) breast cancer survivors, yet are rarely addressed in routine oncology care. Lack of provider training remains a key barrier to…
Salgado GC, Trivelin PCO, Razavi BS et al. · 2026 · Preprint
Abstract Aim This study aimed to evaluate the activity and spatial distribution of enzymes (phosphatase, chitinase, and β-glucosidase) in monoculture and intercropping systems of tomato (Solanum lycopersicum L.) and jack bean (Canavalia…
Azarpira M, Gascoin JC · 2026 · Studies in health technology and informatics
Osteoarticular infections (OAIs) remain challenging, particularly in the context of rising antimicrobial resistance. Using the MIMIC-IV database, this study applies a structured informatics workflow to characterize inflammatory marker (IM)…
Mans K, Lyden E, Burrows J et al. · 2026 · Academic pediatrics
Objective Documentation in the electronic medical record (EMR) is a core Entrustable Professional Activity for medical students, yet opportunities for participation remain limited. Following a policy change allowing physicians to bill…
Rojczyk A, Šturm P, Przedlacka J et al. · 2026 · Language and speech
Previous research on imitation in L1 has shown that explicit instructions generally generate more robust convergence with the model talker than implicit instructions. However, this regularity has not gained sufficient empirical attention…
Christensen AB, Cochran GL, Avedissian SN et al. · 2026 · Infection control and hospital epidemiology
Background Prospective audit and feedback (PAF) is a core antimicrobial stewardship strategy. Discontinuing PAF in favor of alternative interventions has not been previously evaluated. Methods This descriptive study assessed changes in…
Meng Y, Ren X, Li R et al. · 2026 · Experimental hematology
Platelets are produced via a canonical pathway emanating from multilineage hematopoietic stem cells (ML-HSCs) and a faster, direct pathway used by platelet-biased (P-) HSCs where the latter circumvents progenitors intermediate between HSCs…
Porat DB, Abuhasira S, Ekka-Zohar A · 2026 · Preprint
Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been hypothesized to increase vulnerability to post-traumatic stress disorder (PTSD) due to emotional dysregulation, impulsivity, and executive function deficits. Most…
Jadhav R, Demirbas Uzel G, Charest J et al. · 2026 · Microorganisms
The filamentous fungus Trichoderma reesei is one of the most important workhorses for industrial enzyme production, but the cellular mechanisms that balance protein folding stress with secretion, such as the unfolded protein response (UPR)…
Bayhan GI, Aydın Altuntaş C, Cevahir N · 2026 · Journal of infection in developing countries
Objective Hand hygiene (HH) is a fundamental infection prevention measure in healthcare settings, playing a crucial role in reducing healthcare-associated infections (HAIs). Despite its importance, HH compliance remains suboptimal…
Gassé E, Brill A · 2026 · The western journal of emergency medicine
Introduction As public access to tetrahydrocannabinol (THC) products expands under state legalization, there is concern for increased use in adolescents under 18 years of age and its subsequent effects. Adverse effects of THC use have been…
Panaitof SC, Kermagi MM · 2026 · Archives of insect biochemistry and physiology
Dopamine has diverse roles in the regulation of reproduction and social behaviors in insects. In the burying beetle, Nicrophorus orbicollis, a species with extended care, our previous work has shown that brain dopamine levels increase…
Majoe M, Stolarek N, Vizueta J et al. · 2026 · Journal of evolutionary biology
Colonies of insects with morphologically distinct castes have been called superorganisms because the function of their queens and workers is analogous to the germline and soma in metazoan bodies. In the case of formicoid ants, workers…
Rodrigue JR, Fleishman A, Schold JD et al. · 2026 · Transplantation
Background Lost wages following living donation may deter patients from pursuing living donor kidney transplantation (LDKT) and potential donors from being evaluated. Methods We randomized patients undergoing transplant evaluation to 1 of…
Quispe M, Silva Rochefort B, Rojas MJ et al. · 2026 · Preprint
Seasonal reproduction in birds is commonly regulated by photoperiod, and passerines are generally considered long-day breeders. The Java sparrow (Padda oryzivora) has been proposed as a possible exception, but experimental evidence for…
Ichishima J, Nakakariya M, Kimura H · 2026 · Scientific reports
Narcolepsy type 1 (NT1) is caused by a significant loss of orexin-producing neurons. In clinical trials, multiple orexin receptor 2 (OX2R)-selective agonists (e.g., danavorexton, TAK-994, and oveporexton) improved wakefulness and decreased…
Toft S, Skalshøi MR, Brun-Witt L et al. · 2026 · Preprint
Balancing of macronutrient intake assumes that animals change their food preferences to increase consumption of the deficient nutrients and/or decrease consumption of nu-trients in excess. Harvestmen are generalist predators that consume…
Dulli L, Gbonon V, Touré F et al. · 2026 · Preprint
Background Mass Drug Administration (MDA) of azithromycin for the elimination of trachoma and, more recently, for the reduction of child mortality, are public health strategies shown, with mixed results, to contribute to the development of…
Ewers C, Keirsebelik H, Wang C et al. · 2026 · Preprint
Abstract Invasive species are one of the main drivers of global change. Gene flow among divergent lineages in the introduced range is frequently observed and has the potential to increase genetic diversity and adaptive potential. How much…
Wani MM, Yalcinkaya A, Ali AA et al. · 2026 · Preprint
Abstract Background Major international sporting events are commonly perceived to increase trauma-related healthcare utilization. However, data specific to pediatric orthopaedic trauma are limited, particularly within centralized…
Bachelder J, Tolu J, Winkel LH et al. · 2026 · Preprint
Organic amendments provide crops with nutrients, but can also add pollutants. Yet the fate of micronutrients such as zinc (Zn) and pollutants such as cadmium (Cd) in soil-crop systems is difficult to predict because of the complexity of…
Yun G, Seo JW, Koo JR et al. · 2026 · Kidney research and clinical practice
Background Hyponatremia undercorrection (i.e., nonoptimal correction) is insufficient to resolve cerebral edema and is associated with poor clinical outcomes. This study aimed to identify risk factors of undercorrection under controlled…
Normand-Gravier T, Solsona R, Bertrand-Gaday C et al. · 2026 · Experimental physiology
Recent evidence suggests that heat treatment (HT) and resistance training can limit skeletal muscle mass loss during immobilization. However, the effects of repeated HT sessions combined with hybrid exercises (EX), which promote both…
Yang Y, Zhou J, Zhao L et al. · 2026 · BMC pregnancy and childbirth
Introduction Compared with early cord clamping (ECC), delayed cord clamping (DCC) facilitates improved placental transfusion and increases blood volume in singleton pregnancies. However, evidence supporting the use of DCC in twins…
Bar-On O, Less Elazari S, Ben-Zvi H et al. · 2026 · Respiration; international review of thoracic diseases
Introduction The prevalence and clinical significance of non-tuberculous mycobacteria (NTM) in individuals with primary ciliary dyskinesia (PCD) remain unclear, with most data extrapolated from cystic fibrosis. This first national…
Berg J, Wang AI, Madssen E et al. · 2026 · Scientific reports
Insufficient physical activity (PA) among adolescents has deleterious consequences for their health. Exergaming, which combines exercise with gaming, is enjoyable, but the long-term effects of exergaming on adolescent health remain poorly…
Gong J, Xie B, Wei Y et al. · 2026 · Healthcare (Basel, Switzerland)
Background/objectives Pregnancy and childbirth are independent risk factors for pelvic floor injury. The choice of delivery position, as an interventionable factor during labor, has received much attention. This study aimed to assess the…